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The map label for this gene is napA [H]

Identifier: 150398815

GI number: 150398815

Start: 55010

End: 56176

Strand: Reverse

Name: napA [H]

Synonym: Mevan_0056

Alternate gene names: 150398815

Gene position: 56176-55010 (Counterclockwise)

Preceding gene: 150398816

Following gene: 150398810

Centisome position: 3.27

GC content: 27.93

Gene sequence:

>1167_bases
TTGGAACTTTCTTGGGTGCTTTTTACTATTGGAATATTTCTGATTCTTGGAAAAATTGGAAACGAAATAATGTGGCGAAT
CGGGCTTCCAAGTGTTTTTGGGGAATTACTTGTTGGTATAATCTTTGGAAATCTTTTATTTTTTGGAATAATTGATCCAA
AATACATAACTATTCATGAAAATGAAGTTTTTAGTTTTTTATCAACTCTTGGAATAATGTTTCTTTTGTTTTTAAGTGGG
CTTGAAATAGACATACATAAAATTAAAAAAACAGAAGGGATATCTATTATAACCGCACTTCTTGGCGTGGTTTTTCCATT
AATTTTAGGATATATTATTCTTTCAAATTTTGGATATACCAGTAAAGAATCAGTTATTGGCGGAGTAATTCTTACTGCAA
CTAGTATAGGCATAACTACACGACTTTTAATGGATTTAAATGTTTTAAAAACCGATGTAGGTGCTGTAGCCATTAGTGCA
AGCATTATTGATGATTTTTTAGGGATTATTCTTTTAATTGTAGTGATTGGTTCTGGAAATTTATTTGAAATTGCTGGAAA
AATTATATTATTTTTTATATTAACCGGGTATTTAGGCTTTAAATTAATTAAAAAATATATAAATTTAGCTGAAAAATTGC
ACATTGAAAAAAGTGTTTTATCATTTACACTCGGATTAATGTTTTTATTTTCTTTTTTATCCCAAAACTGGTTTGACGTT
GCAATTGAAGGTGCGTTTATGGCTGGTTTAATATTATCGAAAACTTCAGAAGGAAAAATGCTTTCAAAAGAATTGAAATC
TATTGGAAATTCGTTTTTAATCCCTTTATTTTTTATATATACTGGAGCAAAACTTAATTTATACGCATTTTTAAATTTTG
ATGCCCTCTTTCTTTCAGCAATATTTATTATTGTTGGAGTATTCAGTAAATTTTTAGGCTGGGGAATTGGAGCAAAAGTA
TTTGGAAAATGGAATCTTAAAGAAGCATTACAACTTGCTTCAACATCAGTTCCAAGGGCAGAAATTGCGCTAATTAACTT
AATGATTGCAGTTACTGCCGGAATAATTTTGGAAAAAAATATATCAACATTTATTGCTGCAACATTGATATTTATAATGT
TTACAATAATTTTAACACCATTTTTATTTAAAAAAGTATTTAGATAA

Upstream 100 bases:

>100_bases
GTTACTTGCAGTAGTAAATGATGAAAATAGGCTTATAGGAGAAATAAGTCTTAGGATTTTAATAAATAAGTTTTTAGAAC
TATGTTTTTAAGGTGTTTTT

Downstream 100 bases:

>100_bases
GTAATAAAATCGAGTAATTTATATTTAAAAAATAATTATAATTACTAAATATTATAGTATTTTTTCAGCTAAAAGTTCTG
AAATTGACTCATAAATTTTT

Product: sodium/hydrogen exchanger

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 388; Mature: 388

Protein sequence:

>388_residues
MELSWVLFTIGIFLILGKIGNEIMWRIGLPSVFGELLVGIIFGNLLFFGIIDPKYITIHENEVFSFLSTLGIMFLLFLSG
LEIDIHKIKKTEGISIITALLGVVFPLILGYIILSNFGYTSKESVIGGVILTATSIGITTRLLMDLNVLKTDVGAVAISA
SIIDDFLGIILLIVVIGSGNLFEIAGKIILFFILTGYLGFKLIKKYINLAEKLHIEKSVLSFTLGLMFLFSFLSQNWFDV
AIEGAFMAGLILSKTSEGKMLSKELKSIGNSFLIPLFFIYTGAKLNLYAFLNFDALFLSAIFIIVGVFSKFLGWGIGAKV
FGKWNLKEALQLASTSVPRAEIALINLMIAVTAGIILEKNISTFIAATLIFIMFTIILTPFLFKKVFR

Sequences:

>Translated_388_residues
MELSWVLFTIGIFLILGKIGNEIMWRIGLPSVFGELLVGIIFGNLLFFGIIDPKYITIHENEVFSFLSTLGIMFLLFLSG
LEIDIHKIKKTEGISIITALLGVVFPLILGYIILSNFGYTSKESVIGGVILTATSIGITTRLLMDLNVLKTDVGAVAISA
SIIDDFLGIILLIVVIGSGNLFEIAGKIILFFILTGYLGFKLIKKYINLAEKLHIEKSVLSFTLGLMFLFSFLSQNWFDV
AIEGAFMAGLILSKTSEGKMLSKELKSIGNSFLIPLFFIYTGAKLNLYAFLNFDALFLSAIFIIVGVFSKFLGWGIGAKV
FGKWNLKEALQLASTSVPRAEIALINLMIAVTAGIILEKNISTFIAATLIFIMFTIILTPFLFKKVFR
>Mature_388_residues
MELSWVLFTIGIFLILGKIGNEIMWRIGLPSVFGELLVGIIFGNLLFFGIIDPKYITIHENEVFSFLSTLGIMFLLFLSG
LEIDIHKIKKTEGISIITALLGVVFPLILGYIILSNFGYTSKESVIGGVILTATSIGITTRLLMDLNVLKTDVGAVAISA
SIIDDFLGIILLIVVIGSGNLFEIAGKIILFFILTGYLGFKLIKKYINLAEKLHIEKSVLSFTLGLMFLFSFLSQNWFDV
AIEGAFMAGLILSKTSEGKMLSKELKSIGNSFLIPLFFIYTGAKLNLYAFLNFDALFLSAIFIIVGVFSKFLGWGIGAKV
FGKWNLKEALQLASTSVPRAEIALINLMIAVTAGIILEKNISTFIAATLIFIMFTIILTPFLFKKVFR

Specific function: This is a Na(+)/H(+) antiporter. It can mediate sodium uptake when a transmembrane pH gradient is applied [H]

COG id: COG0475

COG function: function code P; Kef-type K+ transport systems, membrane components

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6322367, Length=400, Percent_Identity=25, Blast_Score=73, Evalue=9e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006153
- InterPro:   IPR004771 [H]

Pfam domain/function: PF00999 Na_H_Exchanger [H]

EC number: NA

Molecular weight: Translated: 42742; Mature: 42742

Theoretical pI: Translated: 9.59; Mature: 9.59

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MELSWVLFTIGIFLILGKIGNEIMWRIGLPSVFGELLVGIIFGNLLFFGIIDPKYITIHE
CCCHHHHHHHHHHHHHHHHCCHHEEECCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEC
NEVFSFLSTLGIMFLLFLSGLEIDIHKIKKTEGISIITALLGVVFPLILGYIILSNFGYT
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCC
SKESVIGGVILTATSIGITTRLLMDLNVLKTDVGAVAISASIIDDFLGIILLIVVIGSGN
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
LFEIAGKIILFFILTGYLGFKLIKKYINLAEKLHIEKSVLSFTLGLMFLFSFLSQNWFDV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHH
AIEGAFMAGLILSKTSEGKMLSKELKSIGNSFLIPLFFIYTGAKLNLYAFLNFDALFLSA
HHHHHHHHHHHHHCCCCCHHHHHHHHHHCCHHHHHHHHHHCCCCEEEEEEECHHHHHHHH
IFIIVGVFSKFLGWGIGAKVFGKWNLKEALQLASTSVPRAEIALINLMIAVTAGIILEKN
HHHHHHHHHHHHCCCCCHHHCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCC
ISTFIAATLIFIMFTIILTPFLFKKVFR
HHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MELSWVLFTIGIFLILGKIGNEIMWRIGLPSVFGELLVGIIFGNLLFFGIIDPKYITIHE
CCCHHHHHHHHHHHHHHHHCCHHEEECCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEC
NEVFSFLSTLGIMFLLFLSGLEIDIHKIKKTEGISIITALLGVVFPLILGYIILSNFGYT
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCC
SKESVIGGVILTATSIGITTRLLMDLNVLKTDVGAVAISASIIDDFLGIILLIVVIGSGN
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
LFEIAGKIILFFILTGYLGFKLIKKYINLAEKLHIEKSVLSFTLGLMFLFSFLSQNWFDV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHH
AIEGAFMAGLILSKTSEGKMLSKELKSIGNSFLIPLFFIYTGAKLNLYAFLNFDALFLSA
HHHHHHHHHHHHHCCCCCHHHHHHHHHHCCHHHHHHHHHHCCCCEEEEEEECHHHHHHHH
IFIIVGVFSKFLGWGIGAKVFGKWNLKEALQLASTSVPRAEIALINLMIAVTAGIILEKN
HHHHHHHHHHHHCCCCCHHHCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCC
ISTFIAATLIFIMFTIILTPFLFKKVFR
HHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1312090; 1325937 [H]