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The map label for this gene is ydeN [H]

Identifier: 150010519

GI number: 150010519

Start: 4805825

End: 4807594

Strand: Direct

Name: ydeN [H]

Synonym: BDI_3966

Alternate gene names: 150010519

Gene position: 4805825-4807594 (Clockwise)

Preceding gene: 150010518

Following gene: 150010520

Centisome position: 99.88

GC content: 46.33

Gene sequence:

>1770_bases
ATGACAAAGTTAGGCGTATTGTTTAGTGTTTTGGGAGTGGGGGCCGGTTGTATTCCGGCTTTCGCTCAAAAACAACTCCC
CAATATCATCGTAATGTTATCGGATGACCAAGGTTGGGGCGATTTGGGCTTCACGGGGAATACCTTCGTGCAAACTCCTA
ATATAGATCGTATCGCTCATGAGGGAACGATTTTGGAGAATTTTTATGTCTGTCCGGTGTCATCCCCGACGAGGGCGGAG
TTCTTGACCGGACGCTATCATGTACGGAGTGGCGTTAATTCTACGACCGGGGGAGGCGAGCGCTTTAATCTAGGAGAGAA
AACGATCGCGGAATATTTCCGGGAGGCCGGATACGCTACCTCTCTATTTGGAAAATGGCATAGTGGTACGCAATATCCCT
ACCATCCGAACGCAAGGGGCTTCGAGGAGTTCTATGGTTTTTGTTCCGGGCATTGGGGGAATTATTGGAACCCGGTGTTG
GAACATAACGGAGAGATTATTTCGGGCGAGGGCTTTATCATAGATGATCTGACCGATAAAGCCTTGGATTATATACGTGA
TCATAAAGAACATCCATTCTTTATGTTCTTGTCTTATAACACACCTCATAGTCCGATGCAAGTCCCGGATAGTTGGTGGA
ACCGTGTAAAAGATCGTACCTTGTCGCAGCGAGCTACTTTCCCGGAGCAAGAAGATACTACGTTTACGAAAGCGGCTTTG
GCCTTGGCCGAGAATTTAGATTGGAATATCGGACGTGTATTGTCTTTGTTACATTCATTGGATTTGGAACAAGAGACGAT
TGTTATTTATTTCTCGGATAACGGCCCGAATAGTTTCCGGTGGAATGGTGGGATGAAAGGGCGAAAAGGCTCTACGGATG
AAGGGGGTGTTCGTTCGCCGTTTTGTATCCGTTGGCCGGGACACATAAGGAAAGGGGCCGTGGAAACCCAGTTGTCCGGG
GCTATAGACTTAATCCCTACTTTATTAGGTTTGGCGGGAATAGAATATACCCCGTTAAGGAAACTGGACGGAATCGATTG
GGGACAGCGATTGCTGGATGAGAAAGCTCCTGCTATAGATCGGGTTTTATATAGTTATTGGGGAGGTAAGACGAGTGTGC
GTATCTCATATTATCTATTGGATGCGGAAGATCATTTATATAAAACGGATATAGATCGTGAGCAACGGAAGGATGTATCG
GATAAAGAACCCGAGATATATGAGCGGATGAAGCGTTATTCGAATTGGTTTAAGGATGAGTTACTGGCGGATTTCCCGAA
GAAGGATACCCGTCCGTTTATAATCGGTCATCCGCGGGAAACCTATTCAAAGCTACCGGCCCGGGATGCGAGGATATCTG
GCCCGATCGAACGCTCCAACCGTTATCCGAATTGTTCTTATTTTACGAATTGGAAAAGCCCGGAAGCGGAGATAAGCTGG
AATGTGGAGGTTGAGGAATCCGGTTTGTTCGAGGCTTTTATCTATTATACTTGCGATAAACGAAATATAGGCTCTACTTT
TGAACTTCGTACGGACCGGGATGCCGAGAATCTTGTATTTACATTGGATCAAGTAAATGACCAACCCATGCTCGGTGCGG
ATTTGGATAGGGTTCTCCGGGAGGAGTCTTATGTGAAAGGATTTGCTCCTTGCTCTGTCGGTATGATTTCCTTATCGAAA
GGTGCGGCTACTTTATCCTTGCAAGCGAAAACGATCCGGAATGAGGAGGCCATGAATTTTTGGATGTTGGTGCTAAAACG
AGTGAAATGA

Upstream 100 bases:

>100_bases
CATTGCGAATGAGCTTTCCGCGTTGTTGAAGAAATTGTTGGATCAAGGATATAGCCGTCCGCAATAAAGGTAATCTTGAT
TAGGCAAAAAGTTGAATCGA

Downstream 100 bases:

>100_bases
GTCTAAGATTGAAAAAAGTTGTATAACTATTTGCCAGTTATCAAATAATCACTACCTTTGCACCGCAAAATTTTTTATTA
ATCAATATTAAACAGCGTTT

Product: N-acetylgalactosamine 6-sulfatase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 589; Mature: 588

Protein sequence:

>589_residues
MTKLGVLFSVLGVGAGCIPAFAQKQLPNIIVMLSDDQGWGDLGFTGNTFVQTPNIDRIAHEGTILENFYVCPVSSPTRAE
FLTGRYHVRSGVNSTTGGGERFNLGEKTIAEYFREAGYATSLFGKWHSGTQYPYHPNARGFEEFYGFCSGHWGNYWNPVL
EHNGEIISGEGFIIDDLTDKALDYIRDHKEHPFFMFLSYNTPHSPMQVPDSWWNRVKDRTLSQRATFPEQEDTTFTKAAL
ALAENLDWNIGRVLSLLHSLDLEQETIVIYFSDNGPNSFRWNGGMKGRKGSTDEGGVRSPFCIRWPGHIRKGAVETQLSG
AIDLIPTLLGLAGIEYTPLRKLDGIDWGQRLLDEKAPAIDRVLYSYWGGKTSVRISYYLLDAEDHLYKTDIDREQRKDVS
DKEPEIYERMKRYSNWFKDELLADFPKKDTRPFIIGHPRETYSKLPARDARISGPIERSNRYPNCSYFTNWKSPEAEISW
NVEVEESGLFEAFIYYTCDKRNIGSTFELRTDRDAENLVFTLDQVNDQPMLGADLDRVLREESYVKGFAPCSVGMISLSK
GAATLSLQAKTIRNEEAMNFWMLVLKRVK

Sequences:

>Translated_589_residues
MTKLGVLFSVLGVGAGCIPAFAQKQLPNIIVMLSDDQGWGDLGFTGNTFVQTPNIDRIAHEGTILENFYVCPVSSPTRAE
FLTGRYHVRSGVNSTTGGGERFNLGEKTIAEYFREAGYATSLFGKWHSGTQYPYHPNARGFEEFYGFCSGHWGNYWNPVL
EHNGEIISGEGFIIDDLTDKALDYIRDHKEHPFFMFLSYNTPHSPMQVPDSWWNRVKDRTLSQRATFPEQEDTTFTKAAL
ALAENLDWNIGRVLSLLHSLDLEQETIVIYFSDNGPNSFRWNGGMKGRKGSTDEGGVRSPFCIRWPGHIRKGAVETQLSG
AIDLIPTLLGLAGIEYTPLRKLDGIDWGQRLLDEKAPAIDRVLYSYWGGKTSVRISYYLLDAEDHLYKTDIDREQRKDVS
DKEPEIYERMKRYSNWFKDELLADFPKKDTRPFIIGHPRETYSKLPARDARISGPIERSNRYPNCSYFTNWKSPEAEISW
NVEVEESGLFEAFIYYTCDKRNIGSTFELRTDRDAENLVFTLDQVNDQPMLGADLDRVLREESYVKGFAPCSVGMISLSK
GAATLSLQAKTIRNEEAMNFWMLVLKRVK
>Mature_588_residues
TKLGVLFSVLGVGAGCIPAFAQKQLPNIIVMLSDDQGWGDLGFTGNTFVQTPNIDRIAHEGTILENFYVCPVSSPTRAEF
LTGRYHVRSGVNSTTGGGERFNLGEKTIAEYFREAGYATSLFGKWHSGTQYPYHPNARGFEEFYGFCSGHWGNYWNPVLE
HNGEIISGEGFIIDDLTDKALDYIRDHKEHPFFMFLSYNTPHSPMQVPDSWWNRVKDRTLSQRATFPEQEDTTFTKAALA
LAENLDWNIGRVLSLLHSLDLEQETIVIYFSDNGPNSFRWNGGMKGRKGSTDEGGVRSPFCIRWPGHIRKGAVETQLSGA
IDLIPTLLGLAGIEYTPLRKLDGIDWGQRLLDEKAPAIDRVLYSYWGGKTSVRISYYLLDAEDHLYKTDIDREQRKDVSD
KEPEIYERMKRYSNWFKDELLADFPKKDTRPFIIGHPRETYSKLPARDARISGPIERSNRYPNCSYFTNWKSPEAEISWN
VEVEESGLFEAFIYYTCDKRNIGSTFELRTDRDAENLVFTLDQVNDQPMLGADLDRVLREESYVKGFAPCSVGMISLSKG
AATLSLQAKTIRNEEAMNFWMLVLKRVK

Specific function: Unknown

COG id: COG3119

COG function: function code P; Arylsulfatase A and related enzymes

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sulfatase family [H]

Homologues:

Organism=Homo sapiens, GI4503899, Length=401, Percent_Identity=32.1695760598504, Blast_Score=186, Evalue=7e-47,
Organism=Homo sapiens, GI146229331, Length=367, Percent_Identity=32.9700272479564, Blast_Score=149, Evalue=7e-36,
Organism=Homo sapiens, GI146229329, Length=367, Percent_Identity=32.9700272479564, Blast_Score=149, Evalue=7e-36,
Organism=Homo sapiens, GI6005990, Length=367, Percent_Identity=32.9700272479564, Blast_Score=149, Evalue=7e-36,
Organism=Homo sapiens, GI146229324, Length=367, Percent_Identity=32.9700272479564, Blast_Score=149, Evalue=7e-36,
Organism=Homo sapiens, GI109389362, Length=369, Percent_Identity=28.4552845528455, Blast_Score=144, Evalue=2e-34,
Organism=Homo sapiens, GI38569407, Length=362, Percent_Identity=28.7292817679558, Blast_Score=142, Evalue=7e-34,
Organism=Homo sapiens, GI38569405, Length=362, Percent_Identity=28.7292817679558, Blast_Score=142, Evalue=1e-33,
Organism=Homo sapiens, GI59797060, Length=341, Percent_Identity=31.0850439882698, Blast_Score=141, Evalue=2e-33,
Organism=Homo sapiens, GI45430057, Length=425, Percent_Identity=26.5882352941176, Blast_Score=126, Evalue=6e-29,
Organism=Homo sapiens, GI71852586, Length=146, Percent_Identity=40.4109589041096, Blast_Score=107, Evalue=3e-23,
Organism=Homo sapiens, GI157266309, Length=136, Percent_Identity=41.9117647058824, Blast_Score=107, Evalue=3e-23,
Organism=Homo sapiens, GI71852584, Length=146, Percent_Identity=39.7260273972603, Blast_Score=106, Evalue=7e-23,
Organism=Homo sapiens, GI53831991, Length=135, Percent_Identity=41.4814814814815, Blast_Score=101, Evalue=2e-21,
Organism=Homo sapiens, GI58743319, Length=136, Percent_Identity=41.9117647058824, Blast_Score=100, Evalue=5e-21,
Organism=Homo sapiens, GI31742482, Length=138, Percent_Identity=39.8550724637681, Blast_Score=98, Evalue=2e-20,
Organism=Homo sapiens, GI146229327, Length=294, Percent_Identity=29.9319727891156, Blast_Score=96, Evalue=7e-20,
Organism=Homo sapiens, GI4557659, Length=415, Percent_Identity=24.3373493975904, Blast_Score=87, Evalue=7e-17,
Organism=Homo sapiens, GI5360208, Length=326, Percent_Identity=25.1533742331288, Blast_Score=79, Evalue=9e-15,
Organism=Escherichia coli, GI87081924, Length=407, Percent_Identity=30.2211302211302, Blast_Score=147, Evalue=2e-36,
Organism=Escherichia coli, GI1790233, Length=416, Percent_Identity=27.4038461538462, Blast_Score=118, Evalue=1e-27,
Organism=Escherichia coli, GI1790112, Length=359, Percent_Identity=27.0194986072423, Blast_Score=97, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI115533416, Length=438, Percent_Identity=27.6255707762557, Blast_Score=134, Evalue=1e-31,
Organism=Caenorhabditis elegans, GI115533418, Length=430, Percent_Identity=27.4418604651163, Blast_Score=125, Evalue=6e-29,
Organism=Caenorhabditis elegans, GI17568795, Length=365, Percent_Identity=28.2191780821918, Blast_Score=100, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI17559078, Length=218, Percent_Identity=31.651376146789, Blast_Score=86, Evalue=4e-17,
Organism=Drosophila melanogaster, GI281366397, Length=358, Percent_Identity=33.2402234636872, Blast_Score=170, Evalue=2e-42,
Organism=Drosophila melanogaster, GI281366395, Length=358, Percent_Identity=33.2402234636872, Blast_Score=170, Evalue=2e-42,
Organism=Drosophila melanogaster, GI24666163, Length=358, Percent_Identity=33.2402234636872, Blast_Score=170, Evalue=2e-42,
Organism=Drosophila melanogaster, GI24666109, Length=376, Percent_Identity=32.4468085106383, Blast_Score=164, Evalue=1e-40,
Organism=Drosophila melanogaster, GI281363223, Length=377, Percent_Identity=29.1777188328912, Blast_Score=154, Evalue=2e-37,
Organism=Drosophila melanogaster, GI24666175, Length=379, Percent_Identity=30.6068601583113, Blast_Score=144, Evalue=1e-34,
Organism=Drosophila melanogaster, GI24653364, Length=397, Percent_Identity=27.7078085642317, Blast_Score=96, Evalue=7e-20,
Organism=Drosophila melanogaster, GI19922168, Length=407, Percent_Identity=27.2727272727273, Blast_Score=95, Evalue=1e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017849
- InterPro:   IPR017850
- InterPro:   IPR000917 [H]

Pfam domain/function: PF00884 Sulfatase [H]

EC number: 3.1.6.- [C]

Molecular weight: Translated: 67065; Mature: 66934

Theoretical pI: Translated: 5.68; Mature: 5.68

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS00523 SULFATASE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKLGVLFSVLGVGAGCIPAFAQKQLPNIIVMLSDDQGWGDLGFTGNTFVQTPNIDRIAH
CCHHHHHHHHHHCCCCHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCEEEECCCCHHHHC
EGTILENFYVCPVSSPTRAEFLTGRYHVRSGVNSTTGGGERFNLGEKTIAEYFREAGYAT
CCEEEECEEEECCCCCCHHHHHCCHHHHHCCCCCCCCCCCEECCCHHHHHHHHHHCCCEE
SLFGKWHSGTQYPYHPNARGFEEFYGFCSGHWGNYWNPVLEHNGEIISGEGFIIDDLTDK
HHHHCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCHHHHCCCCEEECCCEEEECHHHH
ALDYIRDHKEHPFFMFLSYNTPHSPMQVPDSWWNRVKDRTLSQRATFPEQEDTTFTKAAL
HHHHHHCCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHH
ALAENLDWNIGRVLSLLHSLDLEQETIVIYFSDNGPNSFRWNGGMKGRKGSTDEGGVRSP
HHHHCCCCCHHHHHHHHHHCCCCCCEEEEEEECCCCCCEEECCCCCCCCCCCCCCCCCCC
FCIRWPGHIRKGAVETQLSGAIDLIPTLLGLAGIEYTPLRKLDGIDWGQRLLDEKAPAID
EEEECCCHHHCCCHHHHHCCHHHHHHHHHHHCCCCCCCCHHCCCCCHHHHHHHHCCCHHH
RVLYSYWGGKTSVRISYYLLDAEDHLYKTDIDREQRKDVSDKEPEIYERMKRYSNWFKDE
HHHHHHCCCCEEEEEEEEEECCCCCEEECCCCHHHHCCCCCCCCHHHHHHHHHHHHHHHH
LLADFPKKDTRPFIIGHPRETYSKLPARDARISGPIERSNRYPNCSYFTNWKSPEAEISW
HHHHCCCCCCCCEEEECCHHHHHHCCCCCCCCCCCHHHCCCCCCCCEEECCCCCCCEEEE
NVEVEESGLFEAFIYYTCDKRNIGSTFELRTDRDAENLVFTLDQVNDQPMLGADLDRVLR
EEEECCCCCEEEEEEEEECCCCCCCEEEEECCCCCCCEEEEEECCCCCCCCCHHHHHHHH
EESYVKGFAPCSVGMISLSKGAATLSLQAKTIRNEEAMNFWMLVLKRVK
HHHHHCCCCCCCCCEEEECCCCEEEEEEHHHHCCHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TKLGVLFSVLGVGAGCIPAFAQKQLPNIIVMLSDDQGWGDLGFTGNTFVQTPNIDRIAH
CHHHHHHHHHHCCCCHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCEEEECCCCHHHHC
EGTILENFYVCPVSSPTRAEFLTGRYHVRSGVNSTTGGGERFNLGEKTIAEYFREAGYAT
CCEEEECEEEECCCCCCHHHHHCCHHHHHCCCCCCCCCCCEECCCHHHHHHHHHHCCCEE
SLFGKWHSGTQYPYHPNARGFEEFYGFCSGHWGNYWNPVLEHNGEIISGEGFIIDDLTDK
HHHHCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCHHHHCCCCEEECCCEEEECHHHH
ALDYIRDHKEHPFFMFLSYNTPHSPMQVPDSWWNRVKDRTLSQRATFPEQEDTTFTKAAL
HHHHHHCCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHH
ALAENLDWNIGRVLSLLHSLDLEQETIVIYFSDNGPNSFRWNGGMKGRKGSTDEGGVRSP
HHHHCCCCCHHHHHHHHHHCCCCCCEEEEEEECCCCCCEEECCCCCCCCCCCCCCCCCCC
FCIRWPGHIRKGAVETQLSGAIDLIPTLLGLAGIEYTPLRKLDGIDWGQRLLDEKAPAID
EEEECCCHHHCCCHHHHHCCHHHHHHHHHHHCCCCCCCCHHCCCCCHHHHHHHHCCCHHH
RVLYSYWGGKTSVRISYYLLDAEDHLYKTDIDREQRKDVSDKEPEIYERMKRYSNWFKDE
HHHHHHCCCCEEEEEEEEEECCCCCEEECCCCHHHHCCCCCCCCHHHHHHHHHHHHHHHH
LLADFPKKDTRPFIIGHPRETYSKLPARDARISGPIERSNRYPNCSYFTNWKSPEAEISW
HHHHCCCCCCCCEEEECCHHHHHHCCCCCCCCCCCHHHCCCCCCCCEEECCCCCCCEEEE
NVEVEESGLFEAFIYYTCDKRNIGSTFELRTDRDAENLVFTLDQVNDQPMLGADLDRVLR
EEEECCCCCEEEEEEEEECCCCCCCEEEEECCCCCCCEEEEEECCCCCCCCCHHHHHHHH
EESYVKGFAPCSVGMISLSKGAATLSLQAKTIRNEEAMNFWMLVLKRVK
HHHHHCCCCCCCCCEEEECCCCEEEEEEHHHHCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503 [H]