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The map label for this gene is hutU [H]

Identifier: 150010221

GI number: 150010221

Start: 4452475

End: 4454478

Strand: Direct

Name: hutU [H]

Synonym: BDI_3644

Alternate gene names: 150010221

Gene position: 4452475-4454478 (Clockwise)

Preceding gene: 150010220

Following gene: 150010222

Centisome position: 92.54

GC content: 48.65

Gene sequence:

>2004_bases
ATGGAAATACATCTTGATAACTATTTGCCGGAATATCCTTCCTTCGTTTCCGGTATTCGCCGTGCTCCCGATCGCGGCTA
TTCGCTTACGCCCGCTCAAACAGAAACGGCATTGATGAACGCGCTTCGTTACATCCCTGTTGAATTACATGAGAAGCTAG
CTCCTGAGTTCATGGAGGAATTATTGACCCGGGGACGGATCTATGGTTATCGTTACCGTCCGCAGGGAGACCTGAAAGCG
AAGCCTATCTCTGAATATAAAGGTAAATGTATCGAGGGAAAGGCCTTTCAAGTAATGATCGATAATAACCTTTGCTTTGA
TATCGCTTTGTATCCTTACGAGTTGGTTACGTATGGCGAGACTGGGCAGGTCTGCCAGAATTGGATGCAATATCGTTTGA
TTAAGAAGTATTTGGAGGAGCTGACCGAGGAGCAGACCTTGGTGATCGAATCCGGGCATCCTCTGGGATTGTTTCATTCC
AAGCCGGATGCCCCACGGGTAATTATCACGAACTCCATGATGGTGGGAATGTTCGATAACCAAAAGGATTGGCATGTCGC
CGCCCAGATGGGAGTCGCTAATTATGGACAGATGACGGCCGGAGGTTGGATGTATATCGGCCCGCAAGGTATCGTACACG
GTACGTTTAATACATTATTGAATGCCGGACGTAAGAAATTAGGGATTCCACAAGATAAGGATTTGCGAGGCTATCTGTTT
GTATCTTCCGGTTTAGGAGGAATGAGTGGGGCTCAACCTAAAGCCGCCGTGATTGCCGGTGCTGCCAGTATAATCGCCGA
GGTAGACGCTTCCCGTATCGAGACACGCCGATGCCAAGGATGGGTCCAGCATGTGACGGATGATATGGGGAAAGCTTTCT
CCTTAGCCGACGAGGCGATTCGTAAGAAAGAACCGATCTCTATCGCTTTTCATGGCAATATCGTGGATTTATTGGAATAT
GCCGATAAACAGGGGCTTTCCATCGACCTTTTGAGTGATCAGACCTCGTGTCATGCGGTCTATGAAGGTGGTTATTGTCC
GGTAGGCGTGACGTTTGAGGAACGTACGGAATTATTGGCTCATCACCGGGAAGACTTTTGTGCTTTGGTCGATAAAACGT
TGAAGAGACATTTCGAGGTGATCAAACGTCTGGTTGCCCGGGGTACCTATTTCTTTGACTATGGGAACTCCTTCATGAAA
GCGATCTATGATGCCGGTGTACATGAGATTTCCCGTAACGGTGTGGACGAGAAAGATGGTTTTATATGGCCTTCTTATGT
GGAAGATATCATGGGGCCGGAATTATTTGATTATGGGTACGGTCCTTTCCGCTGGGTATGTTTAAGCGGTAAGCCGGAAG
ATTTGATTCGCACGGATCATGCGGCTATGGCGTGTATCGATCCGACTCGAAGAGGGCAGGATATGGATAATTATAATTGG
ATACGTGACGCGGAGAAGAACCGTTTGGTGGTGGGTACGCAAGCCCGGATCTTATATCAAGACGCTGAGGGGCGCTTGAA
GATCGCCCTTGAGTTTAACCGAATGGTACGTGATGGGGAGGTAGGCCCGATTATGTTGGGACGAGACCATCATGACGTGA
GCGGTACGGATTCTCCATTCCGTGAGACCTCTAATATACGGGACGGAAGCAATGTGATGGCTGATATGGCGGTGCAGTGC
TTTGCTGGAAATGCCGCCCGGGGTATGAGCTTGGTCGCTCTTCATAATGGTGGAGGGGTTGGTATCGGTAAGGCGATAAA
CGGAGGTTTTGGTATGGTTCTCGATGGTAGTGAGCGGGTGGATGAGATACTTCGTTCCGCTATGATATGGGACGTGATGG
GGGGTGTCGCCCGTCGCTCATGGGCTCGTAACCCGAATGCGATGCGTACGAGCGCTACTTTCAATGAGAATCGTGGCGAA
CAGTATCATATTACCCTCCCGTATATCCCGGAGAAAGCGTTTATTCATGAAATCGTACAAACATCATTAAATAAAAAGGT
ATGA

Upstream 100 bases:

>100_bases
GGAATGATAATTGGCTGGGATTTGGATAATCGCTAACTTGTCGGCGCTGAATCCGTGAAATTCCTTGCAGATTGTAAGCA
CCTACTAAATCATTCACGTT

Downstream 100 bases:

>100_bases
GTACTTGGAATAAGATTATGGAATGTGTCCCTAACTTCAGTGAAGGACGGGATTTGGAGAAGATAGATAAGATCGTAGCG
CCTTTCCGGGCTAAGACGGG

Product: urocanate hydratase

Products: NA

Alternate protein names: Urocanase; Imidazolonepropionate hydrolase [H]

Number of amino acids: Translated: 667; Mature: 667

Protein sequence:

>667_residues
MEIHLDNYLPEYPSFVSGIRRAPDRGYSLTPAQTETALMNALRYIPVELHEKLAPEFMEELLTRGRIYGYRYRPQGDLKA
KPISEYKGKCIEGKAFQVMIDNNLCFDIALYPYELVTYGETGQVCQNWMQYRLIKKYLEELTEEQTLVIESGHPLGLFHS
KPDAPRVIITNSMMVGMFDNQKDWHVAAQMGVANYGQMTAGGWMYIGPQGIVHGTFNTLLNAGRKKLGIPQDKDLRGYLF
VSSGLGGMSGAQPKAAVIAGAASIIAEVDASRIETRRCQGWVQHVTDDMGKAFSLADEAIRKKEPISIAFHGNIVDLLEY
ADKQGLSIDLLSDQTSCHAVYEGGYCPVGVTFEERTELLAHHREDFCALVDKTLKRHFEVIKRLVARGTYFFDYGNSFMK
AIYDAGVHEISRNGVDEKDGFIWPSYVEDIMGPELFDYGYGPFRWVCLSGKPEDLIRTDHAAMACIDPTRRGQDMDNYNW
IRDAEKNRLVVGTQARILYQDAEGRLKIALEFNRMVRDGEVGPIMLGRDHHDVSGTDSPFRETSNIRDGSNVMADMAVQC
FAGNAARGMSLVALHNGGGVGIGKAINGGFGMVLDGSERVDEILRSAMIWDVMGGVARRSWARNPNAMRTSATFNENRGE
QYHITLPYIPEKAFIHEIVQTSLNKKV

Sequences:

>Translated_667_residues
MEIHLDNYLPEYPSFVSGIRRAPDRGYSLTPAQTETALMNALRYIPVELHEKLAPEFMEELLTRGRIYGYRYRPQGDLKA
KPISEYKGKCIEGKAFQVMIDNNLCFDIALYPYELVTYGETGQVCQNWMQYRLIKKYLEELTEEQTLVIESGHPLGLFHS
KPDAPRVIITNSMMVGMFDNQKDWHVAAQMGVANYGQMTAGGWMYIGPQGIVHGTFNTLLNAGRKKLGIPQDKDLRGYLF
VSSGLGGMSGAQPKAAVIAGAASIIAEVDASRIETRRCQGWVQHVTDDMGKAFSLADEAIRKKEPISIAFHGNIVDLLEY
ADKQGLSIDLLSDQTSCHAVYEGGYCPVGVTFEERTELLAHHREDFCALVDKTLKRHFEVIKRLVARGTYFFDYGNSFMK
AIYDAGVHEISRNGVDEKDGFIWPSYVEDIMGPELFDYGYGPFRWVCLSGKPEDLIRTDHAAMACIDPTRRGQDMDNYNW
IRDAEKNRLVVGTQARILYQDAEGRLKIALEFNRMVRDGEVGPIMLGRDHHDVSGTDSPFRETSNIRDGSNVMADMAVQC
FAGNAARGMSLVALHNGGGVGIGKAINGGFGMVLDGSERVDEILRSAMIWDVMGGVARRSWARNPNAMRTSATFNENRGE
QYHITLPYIPEKAFIHEIVQTSLNKKV
>Mature_667_residues
MEIHLDNYLPEYPSFVSGIRRAPDRGYSLTPAQTETALMNALRYIPVELHEKLAPEFMEELLTRGRIYGYRYRPQGDLKA
KPISEYKGKCIEGKAFQVMIDNNLCFDIALYPYELVTYGETGQVCQNWMQYRLIKKYLEELTEEQTLVIESGHPLGLFHS
KPDAPRVIITNSMMVGMFDNQKDWHVAAQMGVANYGQMTAGGWMYIGPQGIVHGTFNTLLNAGRKKLGIPQDKDLRGYLF
VSSGLGGMSGAQPKAAVIAGAASIIAEVDASRIETRRCQGWVQHVTDDMGKAFSLADEAIRKKEPISIAFHGNIVDLLEY
ADKQGLSIDLLSDQTSCHAVYEGGYCPVGVTFEERTELLAHHREDFCALVDKTLKRHFEVIKRLVARGTYFFDYGNSFMK
AIYDAGVHEISRNGVDEKDGFIWPSYVEDIMGPELFDYGYGPFRWVCLSGKPEDLIRTDHAAMACIDPTRRGQDMDNYNW
IRDAEKNRLVVGTQARILYQDAEGRLKIALEFNRMVRDGEVGPIMLGRDHHDVSGTDSPFRETSNIRDGSNVMADMAVQC
FAGNAARGMSLVALHNGGGVGIGKAINGGFGMVLDGSERVDEILRSAMIWDVMGGVARRSWARNPNAMRTSATFNENRGE
QYHITLPYIPEKAFIHEIVQTSLNKKV

Specific function: Unknown

COG id: COG2987

COG function: function code E; Urocanate hydratase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the urocanase family [H]

Homologues:

Organism=Homo sapiens, GI21389467, Length=655, Percent_Identity=48.3969465648855, Blast_Score=583, Evalue=1e-166,
Organism=Homo sapiens, GI260306182, Length=366, Percent_Identity=47.2677595628415, Blast_Score=315, Evalue=1e-85,
Organism=Caenorhabditis elegans, GI71997891, Length=670, Percent_Identity=46.865671641791, Blast_Score=581, Evalue=1e-166,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000193 [H]

Pfam domain/function: PF01175 Urocanase [H]

EC number: =4.2.1.49 [H]

Molecular weight: Translated: 74687; Mature: 74687

Theoretical pI: Translated: 6.21; Mature: 6.21

Prosite motif: PS01233 UROCANASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEIHLDNYLPEYPSFVSGIRRAPDRGYSLTPAQTETALMNALRYIPVELHEKLAPEFMEE
CEEECCCCCCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHH
LLTRGRIYGYRYRPQGDLKAKPISEYKGKCIEGKAFQVMIDNNLCFDIALYPYELVTYGE
HHHCCCEEEEEECCCCCCCCCCHHHHCCCEECCCEEEEEECCCCEEEEEECCEEEEEECC
TGQVCQNWMQYRLIKKYLEELTEEQTLVIESGHPLGLFHSKPDAPRVIITNSMMVGMFDN
CHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCEEEECCCCCCCEEEEECCEEEEEECC
QKDWHVAAQMGVANYGQMTAGGWMYIGPQGIVHGTFNTLLNAGRKKLGIPQDKDLRGYLF
CCCHHHHHHHCCCCCCCCCCCCEEEECCCCEEEHHHHHHHHCCHHHCCCCCCCCCEEEEE
VSSGLGGMSGAQPKAAVIAGAASIIAEVDASRIETRRCQGWVQHVTDDMGKAFSLADEAI
EECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RKKEPISIAFHGNIVDLLEYADKQGLSIDLLSDQTSCHAVYEGGYCPVGVTFEERTELLA
HCCCCEEEEECCCHHHHHHHHCCCCCEEEEECCCCCEEEEECCCCCEEECCHHHHHHHHH
HHREDFCALVDKTLKRHFEVIKRLVARGTYFFDYGNSFMKAIYDAGVHEISRNGVDEKDG
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCHHHHHHHHHHHHHHHHHCCCCCCCC
FIWPSYVEDIMGPELFDYGYGPFRWVCLSGKPEDLIRTDHAAMACIDPTRRGQDMDNYNW
EECHHHHHHHCCCCHHHCCCCCEEEEEECCCCHHHHHCCCCEEEEECCCCCCCCCCCCCH
IRDAEKNRLVVGTQARILYQDAEGRLKIALEFNRMVRDGEVGPIMLGRDHHDVSGTDSPF
HHCCCCCEEEEECCEEEEEECCCCCEEEEEEEEHHHCCCCCCCEEECCCCCCCCCCCCCC
RETSNIRDGSNVMADMAVQCFAGNAARGMSLVALHNGGGVGIGKAINGGFGMVLDGSERV
HHHCCCCCCHHHHHHHHHHHHCCCCCCCEEEEEEECCCCEEECCCCCCCEEEEECCHHHH
DEILRSAMIWDVMGGVARRSWARNPNAMRTSATFNENRGEQYHITLPYIPEKAFIHEIVQ
HHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCEEEEECCCCCCHHHHHHHHH
TSLNKKV
HHHCCCC
>Mature Secondary Structure
MEIHLDNYLPEYPSFVSGIRRAPDRGYSLTPAQTETALMNALRYIPVELHEKLAPEFMEE
CEEECCCCCCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHH
LLTRGRIYGYRYRPQGDLKAKPISEYKGKCIEGKAFQVMIDNNLCFDIALYPYELVTYGE
HHHCCCEEEEEECCCCCCCCCCHHHHCCCEECCCEEEEEECCCCEEEEEECCEEEEEECC
TGQVCQNWMQYRLIKKYLEELTEEQTLVIESGHPLGLFHSKPDAPRVIITNSMMVGMFDN
CHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCEEEECCCCCCCEEEEECCEEEEEECC
QKDWHVAAQMGVANYGQMTAGGWMYIGPQGIVHGTFNTLLNAGRKKLGIPQDKDLRGYLF
CCCHHHHHHHCCCCCCCCCCCCEEEECCCCEEEHHHHHHHHCCHHHCCCCCCCCCEEEEE
VSSGLGGMSGAQPKAAVIAGAASIIAEVDASRIETRRCQGWVQHVTDDMGKAFSLADEAI
EECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RKKEPISIAFHGNIVDLLEYADKQGLSIDLLSDQTSCHAVYEGGYCPVGVTFEERTELLA
HCCCCEEEEECCCHHHHHHHHCCCCCEEEEECCCCCEEEEECCCCCEEECCHHHHHHHHH
HHREDFCALVDKTLKRHFEVIKRLVARGTYFFDYGNSFMKAIYDAGVHEISRNGVDEKDG
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCHHHHHHHHHHHHHHHHHCCCCCCCC
FIWPSYVEDIMGPELFDYGYGPFRWVCLSGKPEDLIRTDHAAMACIDPTRRGQDMDNYNW
EECHHHHHHHCCCCHHHCCCCCEEEEEECCCCHHHHHCCCCEEEEECCCCCCCCCCCCCH
IRDAEKNRLVVGTQARILYQDAEGRLKIALEFNRMVRDGEVGPIMLGRDHHDVSGTDSPF
HHCCCCCEEEEECCEEEEEECCCCCEEEEEEEEHHHCCCCCCCEEECCCCCCCCCCCCCC
RETSNIRDGSNVMADMAVQCFAGNAARGMSLVALHNGGGVGIGKAINGGFGMVLDGSERV
HHHCCCCCCHHHHHHHHHHHHCCCCCCCEEEEEEECCCCEEECCCCCCCEEEEECCHHHH
DEILRSAMIWDVMGGVARRSWARNPNAMRTSATFNENRGEQYHITLPYIPEKAFIHEIVQ
HHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCEEEEECCCCCCHHHHHHHHH
TSLNKKV
HHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA