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The map label for this gene is icfG [H]

Identifier: 150010173

GI number: 150010173

Start: 4406592

End: 4407755

Strand: Direct

Name: icfG [H]

Synonym: BDI_3596

Alternate gene names: 150010173

Gene position: 4406592-4407755 (Clockwise)

Preceding gene: 150010172

Following gene: 150010174

Centisome position: 91.59

GC content: 48.54

Gene sequence:

>1164_bases
ATGGCGATCAAGATATTAAGCGTAGACGACGAACAGGATCTGGAAGCGTTGCTAACCCAATATTTCCGTCGGAAGATCCG
TAAGGGAGAGTATGAGTTCTCCTTTGCCCATAATGGTTTGGAGGCGTTGAGGATGATGTTGGACCATCCGGACTTTGATA
TCATATTGAGCGATATCAATATGCCGGAGATGGATGGCTTGACATTGCTGACGAAGATTAACGAGATGCGTAACCCGGCC
TTGAAATGTATCATCGTATCGGCTTATGGGGATATGGAGAATATTCGTACCGCCATGAACCATGGTGCTTTCGACTTCGC
TACCAAGCCGATCGATATGGAGGATCTGGAACGTACGATCGAGAAGGCGGTCGAGCAGATTTCTTTTATCAAGGAGGCCC
AAAAGGAACATCATCAGCTAGAGGAGATACAATACGACTTGAACGTGGCACGTGAGATACAGCAATCGATCTTGCCGAAG
CAGTTCCCTCCGTTCCCGCAATATAAGCAATTCGATCTCTACGCGACCATGAGCGCGGCGAAGGCCGTGGGGGGTGATTT
CTATGATTTCTTCTTGGTGGACGATAATCATCTGGGTTTTACGATCGCTGACGTGTCGGATAAGGGGATTCCCGCCGCTA
TTTTCATGGCGATCAGCCGTACGGTGATCCGTGCTACGGCGCTTAGGCAGCTTTCCCCGGCGGTCTGCATGAAGGAATCG
AATGATCTATTGTGCCGTGAGAGTGTCAATGGGATGTTTGTCACTACTTTTTATGCGATCTTGAATATCCATACGGGCGA
CGTGGTTTATTGCAATGGGGGGCATAATCGTCCGGTTTGGATTCGTAAGAACGATAAGGTATCTCTTTTGCCGATGACTG
GTGGGATGGCCTTGGGAGTCGTGCCGGGATTAGCTTATAAAGAACAATCCTTGAAACTGGAAGCGGGAGACAGCTTGTTC
CTCTATACGGATGGAATCAGTGAGGCGATGAACCTGCGGAATGAGCAATATGGAGATATCCGTTTGGTAGAGGCTTGTAG
CTCCGTGAAGAACCAATCCCCCAAATCCATGATCGAAGGTATATCCGAATCCGTCCAATCATTCGTGAACGGCGCTACGC
AGAGCGATGATATTACGATGTTGGCGCTGACTTATAAAGGATAA

Upstream 100 bases:

>100_bases
TAGAGGAGAAGCATGACGGGAAGATAGAGGTGGAATCGAAAGAGGGTGAGTTTACCCGTTTCATATTCCTTATTCCATTA
ACGAAATAAACAGAAGAATT

Downstream 100 bases:

>100_bases
TCATCTGGATAAAGGTAATTTCTTAAAGTTTACTTATATGAAAAAAGCATTTTCTGTATTTTTATCATTTTGCCTGTGTA
CTATTACCATGCTAGGCTTT

Product: two-componnent system response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 387; Mature: 386

Protein sequence:

>387_residues
MAIKILSVDDEQDLEALLTQYFRRKIRKGEYEFSFAHNGLEALRMMLDHPDFDIILSDINMPEMDGLTLLTKINEMRNPA
LKCIIVSAYGDMENIRTAMNHGAFDFATKPIDMEDLERTIEKAVEQISFIKEAQKEHHQLEEIQYDLNVAREIQQSILPK
QFPPFPQYKQFDLYATMSAAKAVGGDFYDFFLVDDNHLGFTIADVSDKGIPAAIFMAISRTVIRATALRQLSPAVCMKES
NDLLCRESVNGMFVTTFYAILNIHTGDVVYCNGGHNRPVWIRKNDKVSLLPMTGGMALGVVPGLAYKEQSLKLEAGDSLF
LYTDGISEAMNLRNEQYGDIRLVEACSSVKNQSPKSMIEGISESVQSFVNGATQSDDITMLALTYKG

Sequences:

>Translated_387_residues
MAIKILSVDDEQDLEALLTQYFRRKIRKGEYEFSFAHNGLEALRMMLDHPDFDIILSDINMPEMDGLTLLTKINEMRNPA
LKCIIVSAYGDMENIRTAMNHGAFDFATKPIDMEDLERTIEKAVEQISFIKEAQKEHHQLEEIQYDLNVAREIQQSILPK
QFPPFPQYKQFDLYATMSAAKAVGGDFYDFFLVDDNHLGFTIADVSDKGIPAAIFMAISRTVIRATALRQLSPAVCMKES
NDLLCRESVNGMFVTTFYAILNIHTGDVVYCNGGHNRPVWIRKNDKVSLLPMTGGMALGVVPGLAYKEQSLKLEAGDSLF
LYTDGISEAMNLRNEQYGDIRLVEACSSVKNQSPKSMIEGISESVQSFVNGATQSDDITMLALTYKG
>Mature_386_residues
AIKILSVDDEQDLEALLTQYFRRKIRKGEYEFSFAHNGLEALRMMLDHPDFDIILSDINMPEMDGLTLLTKINEMRNPAL
KCIIVSAYGDMENIRTAMNHGAFDFATKPIDMEDLERTIEKAVEQISFIKEAQKEHHQLEEIQYDLNVAREIQQSILPKQ
FPPFPQYKQFDLYATMSAAKAVGGDFYDFFLVDDNHLGFTIADVSDKGIPAAIFMAISRTVIRATALRQLSPAVCMKESN
DLLCRESVNGMFVTTFYAILNIHTGDVVYCNGGHNRPVWIRKNDKVSLLPMTGGMALGVVPGLAYKEQSLKLEAGDSLFL
YTDGISEAMNLRNEQYGDIRLVEACSSVKNQSPKSMIEGISESVQSFVNGATQSDDITMLALTYKG

Specific function: Involved in cross-regulation of inorganic carbon and glucose metabolisms [H]

COG id: COG2208

COG function: function code TK; Serine phosphatase RsbU, regulator of sigma subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PP2C-like domain [H]

Homologues:

Organism=Escherichia coli, GI1788550, Length=140, Percent_Identity=35.7142857142857, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1790437, Length=126, Percent_Identity=36.5079365079365, Blast_Score=76, Evalue=5e-15,
Organism=Escherichia coli, GI1790299, Length=98, Percent_Identity=39.7959183673469, Blast_Score=69, Evalue=6e-13,
Organism=Escherichia coli, GI1788905, Length=96, Percent_Identity=36.4583333333333, Blast_Score=69, Evalue=7e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003660
- InterPro:   IPR001932
- InterPro:   IPR010822 [H]

Pfam domain/function: PF00672 HAMP; PF07228 SpoIIE [H]

EC number: NA

Molecular weight: Translated: 43434; Mature: 43303

Theoretical pI: Translated: 4.70; Mature: 4.70

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAIKILSVDDEQDLEALLTQYFRRKIRKGEYEFSFAHNGLEALRMMLDHPDFDIILSDIN
CEEEEEECCCHHHHHHHHHHHHHHHHHCCCEEEEHHHCCHHHHHHHHCCCCCEEEEECCC
MPEMDGLTLLTKINEMRNPALKCIIVSAYGDMENIRTAMNHGAFDFATKPIDMEDLERTI
CCCCCCHHHHHHHHHHCCCEEEEEEEECCCCHHHHHHHHHCCCCCCCCCCCCHHHHHHHH
EKAVEQISFIKEAQKEHHQLEEIQYDLNVAREIQQSILPKQFPPFPQYKQFDLYATMSAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEHHHHHHHH
KAVGGDFYDFFLVDDNHLGFTIADVSDKGIPAAIFMAISRTVIRATALRQLSPAVCMKES
HHHCCCEEEEEEEECCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHCCC
NDLLCRESVNGMFVTTFYAILNIHTGDVVYCNGGHNRPVWIRKNDKVSLLPMTGGMALGV
CCEEEHHCCCCCHHHHHHHHHEECCCCEEEECCCCCCCEEEECCCCEEEEEECCCCHHHH
VPGLAYKEQSLKLEAGDSLFLYTDGISEAMNLRNEQYGDIRLVEACSSVKNQSPKSMIEG
CCCCCCCCCCEEEECCCEEEEEECCHHHHHHCCCCCCCCCHHHHHHHHHHCCCHHHHHHH
ISESVQSFVNGATQSDDITMLALTYKG
HHHHHHHHHCCCCCCCCEEEEEEEECC
>Mature Secondary Structure 
AIKILSVDDEQDLEALLTQYFRRKIRKGEYEFSFAHNGLEALRMMLDHPDFDIILSDIN
EEEEEECCCHHHHHHHHHHHHHHHHHCCCEEEEHHHCCHHHHHHHHCCCCCEEEEECCC
MPEMDGLTLLTKINEMRNPALKCIIVSAYGDMENIRTAMNHGAFDFATKPIDMEDLERTI
CCCCCCHHHHHHHHHHCCCEEEEEEEECCCCHHHHHHHHHCCCCCCCCCCCCHHHHHHHH
EKAVEQISFIKEAQKEHHQLEEIQYDLNVAREIQQSILPKQFPPFPQYKQFDLYATMSAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEHHHHHHHH
KAVGGDFYDFFLVDDNHLGFTIADVSDKGIPAAIFMAISRTVIRATALRQLSPAVCMKES
HHHCCCEEEEEEEECCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHCCC
NDLLCRESVNGMFVTTFYAILNIHTGDVVYCNGGHNRPVWIRKNDKVSLLPMTGGMALGV
CCEEEHHCCCCCHHHHHHHHHEECCCCEEEECCCCCCCEEEECCCCEEEEEECCCCHHHH
VPGLAYKEQSLKLEAGDSLFLYTDGISEAMNLRNEQYGDIRLVEACSSVKNQSPKSMIEG
CCCCCCCCCCEEEECCCEEEEEECCHHHHHHCCCCCCCCCHHHHHHHHHHCCCHHHHHHH
ISESVQSFVNGATQSDDITMLALTYKG
HHHHHHHHHCCCCCCCCEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8075401; 8905231 [H]