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The map label for this gene is fimA [H]

Identifier: 150010078

GI number: 150010078

Start: 4284614

End: 4286005

Strand: Direct

Name: fimA [H]

Synonym: BDI_3498

Alternate gene names: 150010078

Gene position: 4284614-4286005 (Clockwise)

Preceding gene: 150010077

Following gene: 150010079

Centisome position: 89.05

GC content: 39.66

Gene sequence:

>1392_bases
ATGAAACTTAGAAATTTATTATTCGGGACAATGATCGCTTGCGTGTTCGCGGCGTGTTCAAACGAGGATGATCCTATCCC
TAGCGTGGATCCGACACCGGAGACAGGGATTGCGGATCTTACAGTTGTGGTAAAGAATTTGGCAAAGAATACACAGACAA
AAGCTGCTGATGATTCTAATGCTAAAGAGGGCGAAACTGCGATTCACAATTTGTTTGTGGTACTTTATAATGAGGATGGG
ACATTCTTGCAAGTTAGTGATATTACTGCTAATAAGGATGAAGAGCAAACTAATTCAAACAATGAGATTCAGTTTAAGGG
ATTAAAGGCTGGTGCTTCTTATCGTGCGTTGGCTTTCGCTAATGTCCCCAAAGAGGCTCTTACTGCAACTGCTAACTCTT
TTGATTTGACATCTGCTTACTATGTCTTAACCGGTGCAGAAGCGAATGGATTGCCTATGAGTAGTGGAATTAGTCCAGTA
TTCACTCTTGCTGAAGGTGAAAATTATTATGGTTACTCAAACGCTACAGGAGGAAACAGTATTGAATCTGGAAAACCTTT
AGGATTAATTAGAAATGTGGCTCGTGTGGAATTGAGTGCTCTTTCTTTGGATATGACTCAAGTCAAGGTTAATAATAGTC
AAAAATACAAATCAGGAACAATTAAGTTTGTGCCTAAAGATGTTTTTGTATTACATGGTCGTAAAAAAGCGAATGTGGCA
GACCAAAGCATAAGTAATACTGCGTGGTTCAATCTGCCAGATAAGGTTTGGGGTAATATTGCCGCTACTTATGAAACAGC
TAATAGTGATGATTATTATTCCGGAACCAACTCTAGTAACTCATTCGGCCGTTTTGCTGGAACTGTCGATGCTGCTAATT
ATATAAAGGCATTGAGTACAGCAGAAACAACATATACTCAGAATTGGGATGGTACTGCTATTACCGGAAGTAAAGCAATT
ACTCTTGCTAATTCTTTATATTTTTATGTGTTGCCTAATGATCAGACAAAAGCGGCCAGAGAACAAGAAGATCCGGAAGA
AGAAGGCCAGGCTTTCGTCTTGGATAAAACAACTTTGGCATCCGAATTGGTAATCAGTGGTGAAGTTTATATAAAAGCTA
TAATGAACGATAACACATCTTGGACATTCGGCGAAGAGAGTACTCCTGTATTGCGCTATTGGCCGATAAAGATTGGTATC
GATGGATTAGATAGTGAAGACACATATTATGGTCAGGTACATAGAAACGTGGTTTATAACATTTCCGCTACTATCGCAGG
TAATGGTTATGCAGATCCTACTCTTCCTAAGGGGGATCCTACAGCTGACTTGTTTGTAAAGACAATGGTTATGAACTGGG
GTACAGCCACTCAAGCTCCTGTTATCGAATAA

Upstream 100 bases:

>100_bases
TTTGAACAAAGAGTTCTTGTTATGTGACTGAAAACTTAAAAAGCAATTGAGAAAGAAAGGTTTATATAAAAGATTTATTA
ACTCATAAAATTATATGTAT

Downstream 100 bases:

>100_bases
TACTTATTCTTTGAATAATAATCAAAAGGCATTCTCTATCAACAGGGAATGCCTTTTTTGTTATAAATATAATATGTCAA
TGCCCGTTGGCAAAGTTAGA

Product: putative fimbrilin

Products: NA

Alternate protein names: Fimbrillin; Fimbrilin; Major fimbrial subunit protein type III [H]

Number of amino acids: Translated: 463; Mature: 463

Protein sequence:

>463_residues
MKLRNLLFGTMIACVFAACSNEDDPIPSVDPTPETGIADLTVVVKNLAKNTQTKAADDSNAKEGETAIHNLFVVLYNEDG
TFLQVSDITANKDEEQTNSNNEIQFKGLKAGASYRALAFANVPKEALTATANSFDLTSAYYVLTGAEANGLPMSSGISPV
FTLAEGENYYGYSNATGGNSIESGKPLGLIRNVARVELSALSLDMTQVKVNNSQKYKSGTIKFVPKDVFVLHGRKKANVA
DQSISNTAWFNLPDKVWGNIAATYETANSDDYYSGTNSSNSFGRFAGTVDAANYIKALSTAETTYTQNWDGTAITGSKAI
TLANSLYFYVLPNDQTKAAREQEDPEEEGQAFVLDKTTLASELVISGEVYIKAIMNDNTSWTFGEESTPVLRYWPIKIGI
DGLDSEDTYYGQVHRNVVYNISATIAGNGYADPTLPKGDPTADLFVKTMVMNWGTATQAPVIE

Sequences:

>Translated_463_residues
MKLRNLLFGTMIACVFAACSNEDDPIPSVDPTPETGIADLTVVVKNLAKNTQTKAADDSNAKEGETAIHNLFVVLYNEDG
TFLQVSDITANKDEEQTNSNNEIQFKGLKAGASYRALAFANVPKEALTATANSFDLTSAYYVLTGAEANGLPMSSGISPV
FTLAEGENYYGYSNATGGNSIESGKPLGLIRNVARVELSALSLDMTQVKVNNSQKYKSGTIKFVPKDVFVLHGRKKANVA
DQSISNTAWFNLPDKVWGNIAATYETANSDDYYSGTNSSNSFGRFAGTVDAANYIKALSTAETTYTQNWDGTAITGSKAI
TLANSLYFYVLPNDQTKAAREQEDPEEEGQAFVLDKTTLASELVISGEVYIKAIMNDNTSWTFGEESTPVLRYWPIKIGI
DGLDSEDTYYGQVHRNVVYNISATIAGNGYADPTLPKGDPTADLFVKTMVMNWGTATQAPVIE
>Mature_463_residues
MKLRNLLFGTMIACVFAACSNEDDPIPSVDPTPETGIADLTVVVKNLAKNTQTKAADDSNAKEGETAIHNLFVVLYNEDG
TFLQVSDITANKDEEQTNSNNEIQFKGLKAGASYRALAFANVPKEALTATANSFDLTSAYYVLTGAEANGLPMSSGISPV
FTLAEGENYYGYSNATGGNSIESGKPLGLIRNVARVELSALSLDMTQVKVNNSQKYKSGTIKFVPKDVFVLHGRKKANVA
DQSISNTAWFNLPDKVWGNIAATYETANSDDYYSGTNSSNSFGRFAGTVDAANYIKALSTAETTYTQNWDGTAITGSKAI
TLANSLYFYVLPNDQTKAAREQEDPEEEGQAFVLDKTTLASELVISGEVYIKAIMNDNTSWTFGEESTPVLRYWPIKIGI
DGLDSEDTYYGQVHRNVVYNISATIAGNGYADPTLPKGDPTADLFVKTMVMNWGTATQAPVIE

Specific function: Fimbrillin is the structural subunit of the fimbriae, that are filamentous appendages on the cell surface. Fimbriae of P.gingivalis are recognized as a major virulence factor as they mediate cell adhesion and play an important role in invasion of periodon

COG id: NA

COG function: NA

Gene ontology:

Cell location: Fimbrium [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the P.gingivalis fimbrillin family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008110 [H]

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 50050; Mature: 50050

Theoretical pI: Translated: 4.36; Mature: 4.36

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLRNLLFGTMIACVFAACSNEDDPIPSVDPTPETGIADLTVVVKNLAKNTQTKAADDSN
CCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCC
AKEGETAIHNLFVVLYNEDGTFLQVSDITANKDEEQTNSNNEIQFKGLKAGASYRALAFA
CCCCHHEEEEEEEEEECCCCCEEEEECCCCCCCHHHCCCCCEEEEEEEECCCCEEEEEEC
NVPKEALTATANSFDLTSAYYVLTGAEANGLPMSSGISPVFTLAEGENYYGYSNATGGNS
CCCHHHHHCCCCCCCCCEEEEEEECCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCC
IESGKPLGLIRNVARVELSALSLDMTQVKVNNSQKYKSGTIKFVPKDVFVLHGRKKANVA
CCCCCCHHHHHHHHHHEEEHEEEEEEEEEECCCCCCCCCCEEEECCEEEEEECCCCCCCC
DQSISNTAWFNLPDKVWGNIAATYETANSDDYYSGTNSSNSFGRFAGTVDAANYIKALST
CCCCCCCEEECCCHHHHCCEEEEEECCCCCCCCCCCCCCCCCCCEECCHHHHHHHHHHHH
AETTYTQNWDGTAITGSKAITLANSLYFYVLPNDQTKAAREQEDPEEEGQAFVLDKTTLA
CCCEEECCCCCCEEECCCEEEEEEEEEEEEECCCCHHHHHCCCCCHHHCCEEEEECHHHH
SELVISGEVYIKAIMNDNTSWTFGEESTPVLRYWPIKIGIDGLDSEDTYYGQVHRNVVYN
HHEEEECCEEEEEEECCCCCEECCCCCCCEEEEEEEEEECCCCCCCCCEEEEEECEEEEE
ISATIAGNGYADPTLPKGDPTADLFVKTMVMNWGTATQAPVIE
EEEEEECCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure
MKLRNLLFGTMIACVFAACSNEDDPIPSVDPTPETGIADLTVVVKNLAKNTQTKAADDSN
CCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCC
AKEGETAIHNLFVVLYNEDGTFLQVSDITANKDEEQTNSNNEIQFKGLKAGASYRALAFA
CCCCHHEEEEEEEEEECCCCCEEEEECCCCCCCHHHCCCCCEEEEEEEECCCCEEEEEEC
NVPKEALTATANSFDLTSAYYVLTGAEANGLPMSSGISPVFTLAEGENYYGYSNATGGNS
CCCHHHHHCCCCCCCCCEEEEEEECCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCC
IESGKPLGLIRNVARVELSALSLDMTQVKVNNSQKYKSGTIKFVPKDVFVLHGRKKANVA
CCCCCCHHHHHHHHHHEEEHEEEEEEEEEECCCCCCCCCCEEEECCEEEEEECCCCCCCC
DQSISNTAWFNLPDKVWGNIAATYETANSDDYYSGTNSSNSFGRFAGTVDAANYIKALST
CCCCCCCEEECCCHHHHCCEEEEEECCCCCCCCCCCCCCCCCCCEECCHHHHHHHHHHHH
AETTYTQNWDGTAITGSKAITLANSLYFYVLPNDQTKAAREQEDPEEEGQAFVLDKTTLA
CCCEEECCCCCCEEECCCEEEEEEEEEEEEECCCCHHHHHCCCCCHHHCCEEEEECHHHH
SELVISGEVYIKAIMNDNTSWTFGEESTPVLRYWPIKIGIDGLDSEDTYYGQVHRNVVYN
HHEEEECCEEEEEEECCCCCEECCCCCCCEEEEEEEEEECCCCCCCCCEEEEEECEEEEE
ISATIAGNGYADPTLPKGDPTADLFVKTMVMNWGTATQAPVIE
EEEEEECCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7902712; 11748193 [H]