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The map label for this gene is afsQ1 [H]

Identifier: 150010077

GI number: 150010077

Start: 4282370

End: 4284271

Strand: Direct

Name: afsQ1 [H]

Synonym: BDI_3497

Alternate gene names: 150010077

Gene position: 4282370-4284271 (Clockwise)

Preceding gene: 150010071

Following gene: 150010078

Centisome position: 89.01

GC content: 42.48

Gene sequence:

>1902_bases
ATGAGATCAAAAGGTTTTAAAGCGAAATTTATGATGGCATTTTGGGGCTTGTTCGTTGAAGCTCATTATATTGCTGCGAA
CAATGATACAATGGAGGGCTCTCAAGGAATTCTACCTTTTATCATTTTACTGATAGTGTCCATATGTGTAATAGCTTTTT
TGAGTTATTATATGTATAGGTTGAAGAAAGAGAATATTGCCAAAGGTGGTGAGCTTATGGCGAGAAACGATGAGCTTCTT
CGGTCTGTCGATGCGTTAAGCGTAAAAAATCGGGAGATCCAACAAATGTTGGTCAATAAAATCCGTGAGACTGATAATTG
GAATAGGGATAATGAGGTAGAACGGGAGGATTTGAAAAAGCGCCTTGAGGAAATGGAAAAGCTCCATAATTCGTTTTTTG
TTGAAACGATTCATGAAATGCGTACTCCACTATCGCTTGTGCTTGGTTCGTTGAGTGAGTTGTTGCAACGTAAAAATGAT
ATTGACTCTAGTGAAGCGACTCAATTATTGTCTGCTTACCGTAATACTTTGGCTCTTCAAGACCTTATCGAGCAATTGCG
AAATACCCGTCATGGAGATGACGTGGCAAACCATCTTCGGATAGCTCGTTATGACATGATCAGTATAACAAAGCAGATTT
GTGATTTATTCGTGGACTGGATAGCCATGAATAATGTGGAATTTCATATTAATACCCAAACCTCTGTTCTTTGGGTCTGG
ATAGATCGTCGGAAGATGGAGTTTGCCTTGCGTGTACTTTTATCTAATGCGTTAAAAAATACCTATCGCTTTGGAAAGAT
CTCGATCAATATTTCCGTGGTGCGCTCGAATGGCAAGGCTTATTGTTCTTTCTCTATCCAAGATGATGGGTTAGGAGAAA
GCGAAAGTACCCGTTTGGGTTTGAAACAGATCGTGGATATGACAGAATCTTCCGGCGCTATTTTCGAAGGAATTTCATCG
GAGGACGAGACGGGAACCCAATATACGATATTGATTCCATTGGGGAGAAGCCATTATATGGAACGTGCCGTGGAATTCAT
CGAGCCGGATGGTGATCTGGTAAAGCTGAATGAGATGCAGAAGGAGGAGATCGCCGAGTTGATCCAAGTTGTTCCGAAAA
AGAAAGAGACCGGGAAGAAAATGTTGGTGATTGATGACAGTGATCAGATCCGTTGGTTCCTGCGTCATGTTTTTGCCAGT
GAGTATCATGTTTCGGAAGCTCATAATGGCCAGGAGGGTGTAGAGATCGCGCGAGTTGAACGGCCGGATTTTATTTTATG
TGACGTGATGATGCCCGTTAAAGATGGGCTTGCTACCTGTCGTGAAATCAAAGGCATCCCAGAATTAGCGCAAGTGCCGG
TTGTCTTGCTAACCGCAAAGGTAGAGAGTGAGGATGTTATAGCTGGCATTGAATGTGGCGCCGATGATTATATAACCAAG
CCATTCGATGTAGAGGTGTTACGAAGTAAGGTAAACAGTTTATTGAAACGTAGGGATGAGATGAGACGTTTCTATACGTC
GAATTCTGTAGGTGCGCATCCCGAGGGAGAGAAAACGGTAAAGAAAGATGATTCCCCTTCCAATCTTTTTATGGATGCGG
TTATCTCAACGATCGAGAAACATTTGGATGACCCTAGTTTTGAGGCGAAGATTTTGGCGGATTCTTTAAACATGAGTCTC
CCTACATTATATAGAAAGATAAAACTCTACTCGGATAGTAGTATATTGGAGCTTACCCGTATGGTACGTTTGAAGAAAGC
CGCCGAGCTGATCAGTATGCAGCGATACTCTATCCAAGAGGTTTCGGAAATGGTCGGCTTCAACGATACCGCCACTTTCC
GTAAGCGTTTTACGGAACAATACGGCGTCACTCCTTCACAGTATCTGCCGGGTAAGAATTAA

Upstream 100 bases:

>100_bases
CCTTTGTAAGGCTGCAAAAAAGTTGAAGATAAAAACGCAAGATTTAAACGAACGTTTTTTACTGGCGTTTTATATAAATA
ACATCTTAATAATCAATGAT

Downstream 100 bases:

>100_bases
TCGTTTTGCCATTTCCCGAATAATCGTCGGGGAATGGCAAAATTTTTTATTTGTTTTTTGAAACGATATTTTTCAACCTC
TTTTTGATAGCCTTACAACG

Product: two-component system sensor histidine kinase/response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 633; Mature: 633

Protein sequence:

>633_residues
MRSKGFKAKFMMAFWGLFVEAHYIAANNDTMEGSQGILPFIILLIVSICVIAFLSYYMYRLKKENIAKGGELMARNDELL
RSVDALSVKNREIQQMLVNKIRETDNWNRDNEVEREDLKKRLEEMEKLHNSFFVETIHEMRTPLSLVLGSLSELLQRKND
IDSSEATQLLSAYRNTLALQDLIEQLRNTRHGDDVANHLRIARYDMISITKQICDLFVDWIAMNNVEFHINTQTSVLWVW
IDRRKMEFALRVLLSNALKNTYRFGKISINISVVRSNGKAYCSFSIQDDGLGESESTRLGLKQIVDMTESSGAIFEGISS
EDETGTQYTILIPLGRSHYMERAVEFIEPDGDLVKLNEMQKEEIAELIQVVPKKKETGKKMLVIDDSDQIRWFLRHVFAS
EYHVSEAHNGQEGVEIARVERPDFILCDVMMPVKDGLATCREIKGIPELAQVPVVLLTAKVESEDVIAGIECGADDYITK
PFDVEVLRSKVNSLLKRRDEMRRFYTSNSVGAHPEGEKTVKKDDSPSNLFMDAVISTIEKHLDDPSFEAKILADSLNMSL
PTLYRKIKLYSDSSILELTRMVRLKKAAELISMQRYSIQEVSEMVGFNDTATFRKRFTEQYGVTPSQYLPGKN

Sequences:

>Translated_633_residues
MRSKGFKAKFMMAFWGLFVEAHYIAANNDTMEGSQGILPFIILLIVSICVIAFLSYYMYRLKKENIAKGGELMARNDELL
RSVDALSVKNREIQQMLVNKIRETDNWNRDNEVEREDLKKRLEEMEKLHNSFFVETIHEMRTPLSLVLGSLSELLQRKND
IDSSEATQLLSAYRNTLALQDLIEQLRNTRHGDDVANHLRIARYDMISITKQICDLFVDWIAMNNVEFHINTQTSVLWVW
IDRRKMEFALRVLLSNALKNTYRFGKISINISVVRSNGKAYCSFSIQDDGLGESESTRLGLKQIVDMTESSGAIFEGISS
EDETGTQYTILIPLGRSHYMERAVEFIEPDGDLVKLNEMQKEEIAELIQVVPKKKETGKKMLVIDDSDQIRWFLRHVFAS
EYHVSEAHNGQEGVEIARVERPDFILCDVMMPVKDGLATCREIKGIPELAQVPVVLLTAKVESEDVIAGIECGADDYITK
PFDVEVLRSKVNSLLKRRDEMRRFYTSNSVGAHPEGEKTVKKDDSPSNLFMDAVISTIEKHLDDPSFEAKILADSLNMSL
PTLYRKIKLYSDSSILELTRMVRLKKAAELISMQRYSIQEVSEMVGFNDTATFRKRFTEQYGVTPSQYLPGKN
>Mature_633_residues
MRSKGFKAKFMMAFWGLFVEAHYIAANNDTMEGSQGILPFIILLIVSICVIAFLSYYMYRLKKENIAKGGELMARNDELL
RSVDALSVKNREIQQMLVNKIRETDNWNRDNEVEREDLKKRLEEMEKLHNSFFVETIHEMRTPLSLVLGSLSELLQRKND
IDSSEATQLLSAYRNTLALQDLIEQLRNTRHGDDVANHLRIARYDMISITKQICDLFVDWIAMNNVEFHINTQTSVLWVW
IDRRKMEFALRVLLSNALKNTYRFGKISINISVVRSNGKAYCSFSIQDDGLGESESTRLGLKQIVDMTESSGAIFEGISS
EDETGTQYTILIPLGRSHYMERAVEFIEPDGDLVKLNEMQKEEIAELIQVVPKKKETGKKMLVIDDSDQIRWFLRHVFAS
EYHVSEAHNGQEGVEIARVERPDFILCDVMMPVKDGLATCREIKGIPELAQVPVVLLTAKVESEDVIAGIECGADDYITK
PFDVEVLRSKVNSLLKRRDEMRRFYTSNSVGAHPEGEKTVKKDDSPSNLFMDAVISTIEKHLDDPSFEAKILADSLNMSL
PTLYRKIKLYSDSSILELTRMVRLKKAAELISMQRYSIQEVSEMVGFNDTATFRKRFTEQYGVTPSQYLPGKN

Specific function: Forms part of a two-component regulatory system AfsQ1/AfsQ2 involved in secondary metabolism [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788394, Length=135, Percent_Identity=31.1111111111111, Blast_Score=85, Evalue=1e-17,
Organism=Escherichia coli, GI1786911, Length=118, Percent_Identity=34.7457627118644, Blast_Score=80, Evalue=6e-16,
Organism=Escherichia coli, GI1789809, Length=221, Percent_Identity=27.1493212669683, Blast_Score=79, Evalue=6e-16,
Organism=Escherichia coli, GI1788550, Length=134, Percent_Identity=31.3432835820896, Blast_Score=76, Evalue=5e-15,
Organism=Escherichia coli, GI1786599, Length=125, Percent_Identity=33.6, Blast_Score=74, Evalue=4e-14,
Organism=Escherichia coli, GI1790863, Length=118, Percent_Identity=36.4406779661017, Blast_Score=70, Evalue=4e-13,
Organism=Escherichia coli, GI1788191, Length=120, Percent_Identity=29.1666666666667, Blast_Score=69, Evalue=7e-13,
Organism=Escherichia coli, GI1790299, Length=104, Percent_Identity=34.6153846153846, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI2367329, Length=119, Percent_Identity=34.453781512605, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1788713, Length=386, Percent_Identity=23.5751295336788, Blast_Score=66, Evalue=7e-12,
Organism=Escherichia coli, GI1790860, Length=110, Percent_Identity=34.5454545454545, Blast_Score=66, Evalue=7e-12,
Organism=Escherichia coli, GI1786784, Length=119, Percent_Identity=31.9327731092437, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI1790437, Length=116, Percent_Identity=32.7586206896552, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI87082012, Length=134, Percent_Identity=29.8507462686567, Blast_Score=65, Evalue=2e-11,
Organism=Escherichia coli, GI1787229, Length=124, Percent_Identity=33.0645161290323, Blast_Score=64, Evalue=4e-11,
Organism=Escherichia coli, GI1787375, Length=119, Percent_Identity=27.7310924369748, Blast_Score=63, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 72447; Mature: 72447

Theoretical pI: Translated: 5.62; Mature: 5.62

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00041 HTH_ARAC_FAMILY_1 ; PS01124 HTH_ARAC_FAMILY_2 ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRSKGFKAKFMMAFWGLFVEAHYIAANNDTMEGSQGILPFIILLIVSICVIAFLSYYMYR
CCCCCCHHHHHHHHHHHHHHHEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
LKKENIAKGGELMARNDELLRSVDALSVKNREIQQMLVNKIRETDNWNRDNEVEREDLKK
HHHHHHCCCCCCEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHH
RLEEMEKLHNSFFVETIHEMRTPLSLVLGSLSELLQRKNDIDSSEATQLLSAYRNTLALQ
HHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
DLIEQLRNTRHGDDVANHLRIARYDMISITKQICDLFVDWIAMNNVEFHINTQTSVLWVW
HHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCEEEEEE
IDRRKMEFALRVLLSNALKNTYRFGKISINISVVRSNGKAYCSFSIQDDGLGESESTRLG
ECCHHHHHHHHHHHHHHHHHHHEEEEEEEEEEEEECCCCEEEEEEECCCCCCCCCHHHHH
LKQIVDMTESSGAIFEGISSEDETGTQYTILIPLGRSHYMERAVEFIEPDGDLVKLNEMQ
HHHHHHHHCCCCCCEECCCCCCCCCCEEEEEEECCHHHHHHHHHHHHCCCCCEEEHHHHH
KEEIAELIQVVPKKKETGKKMLVIDDSDQIRWFLRHVFASEYHVSEAHNGQEGVEIARVE
HHHHHHHHHHCCCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEC
RPDFILCDVMMPVKDGLATCREIKGIPELAQVPVVLLTAKVESEDVIAGIECGADDYITK
CCCEEEEEEHHHHHHHHHHHHHHCCCCHHHHCCEEEEEEECCCCCCEEEEECCCCCCCCC
PFDVEVLRSKVNSLLKRRDEMRRFYTSNSVGAHPEGEKTVKKDDSPSNLFMDAVISTIEK
CCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHH
HLDDPSFEAKILADSLNMSLPTLYRKIKLYSDSSILELTRMVRLKKAAELISMQRYSIQE
HCCCCCCCHHHHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
VSEMVGFNDTATFRKRFTEQYGVTPSQYLPGKN
HHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure
MRSKGFKAKFMMAFWGLFVEAHYIAANNDTMEGSQGILPFIILLIVSICVIAFLSYYMYR
CCCCCCHHHHHHHHHHHHHHHEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
LKKENIAKGGELMARNDELLRSVDALSVKNREIQQMLVNKIRETDNWNRDNEVEREDLKK
HHHHHHCCCCCCEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHH
RLEEMEKLHNSFFVETIHEMRTPLSLVLGSLSELLQRKNDIDSSEATQLLSAYRNTLALQ
HHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
DLIEQLRNTRHGDDVANHLRIARYDMISITKQICDLFVDWIAMNNVEFHINTQTSVLWVW
HHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCEEEEEE
IDRRKMEFALRVLLSNALKNTYRFGKISINISVVRSNGKAYCSFSIQDDGLGESESTRLG
ECCHHHHHHHHHHHHHHHHHHHEEEEEEEEEEEEECCCCEEEEEEECCCCCCCCCHHHHH
LKQIVDMTESSGAIFEGISSEDETGTQYTILIPLGRSHYMERAVEFIEPDGDLVKLNEMQ
HHHHHHHHCCCCCCEECCCCCCCCCCEEEEEEECCHHHHHHHHHHHHCCCCCEEEHHHHH
KEEIAELIQVVPKKKETGKKMLVIDDSDQIRWFLRHVFASEYHVSEAHNGQEGVEIARVE
HHHHHHHHHHCCCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEC
RPDFILCDVMMPVKDGLATCREIKGIPELAQVPVVLLTAKVESEDVIAGIECGADDYITK
CCCEEEEEEHHHHHHHHHHHHHHCCCCHHHHCCEEEEEEECCCCCCEEEEECCCCCCCCC
PFDVEVLRSKVNSLLKRRDEMRRFYTSNSVGAHPEGEKTVKKDDSPSNLFMDAVISTIEK
CCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHH
HLDDPSFEAKILADSLNMSLPTLYRKIKLYSDSSILELTRMVRLKKAAELISMQRYSIQE
HCCCCCCCHHHHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
VSEMVGFNDTATFRKRFTEQYGVTPSQYLPGKN
HHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1339426; 12000953 [H]