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The map label for this gene is frr

Identifier: 150009958

GI number: 150009958

Start: 4095889

End: 4096452

Strand: Direct

Name: frr

Synonym: BDI_3376

Alternate gene names: 150009958

Gene position: 4095889-4096452 (Clockwise)

Preceding gene: 150009957

Following gene: 150009959

Centisome position: 85.13

GC content: 46.99

Gene sequence:

>564_bases
ATGATAGATACGAAACAATTGATCAAAGCAGGGGAAGAGAAGATGACGTTCGCCATTGAGTATCTGGACGAGCAATTGTC
TCACATTCGGGCTGGTAAGGCTAATCCGAAAATCCTCGATTGTGTGAAGGTAATGTATTATGGGGCGCCTGTTCCTCTTA
CTAACGTGGCTACGGTGACGGTTCCAGACGCACGGACTATCATGATCACTCCGTGGGAGAAGAAGATCATCCGCGATATT
GAGAAAGGTATTCTGGATTCTGAGTTAGGTATCACGCCGGAGAATAACGGTGAGGTGATCCGCTTAGGTATTCCTCCGTT
GACTGAGGAGCGTCGCCGTCAATTGGTGAAACAATGTAAGCAGGAGGCGGAGAATGCGAAGATCAGCGTTCGTAACGCTC
GTCGTGACGCTATTGAGGCTTTGAAGAAAAGCATCAAGTCTGATGGGGTTCCCGAGGACGTAGAGAAAGACGCCGAGGCA
GAGGTTCAGAAAATCCATGATAAGTTTATCAAAAAGATCGATGAGCTTTACGCCGCTAAAGAAAAAGAAGTAATGACCGT
TTAA

Upstream 100 bases:

>100_bases
AAATCTTTTGTTAGGGAGTATTTTAATTATATGTTTGCGAAGTTGGAAATCTTTATTACTTTTGTTAATTAAAAGATTCG
CAAACAAAAAACGTATATTT

Downstream 100 bases:

>100_bases
ATAATTGAAAGTTGAAACTTGAGAATTGAGAATTAAGGAACCCCATTGAGTCCTTATTCCAATTCTCAATTTTCAATTCT
CAATTTTCAATTCTCATGAG

Product: ribosome recycling factor

Products: NA

Alternate protein names: RRF; Ribosome-releasing factor

Number of amino acids: Translated: 187; Mature: 187

Protein sequence:

>187_residues
MIDTKQLIKAGEEKMTFAIEYLDEQLSHIRAGKANPKILDCVKVMYYGAPVPLTNVATVTVPDARTIMITPWEKKIIRDI
EKGILDSELGITPENNGEVIRLGIPPLTEERRRQLVKQCKQEAENAKISVRNARRDAIEALKKSIKSDGVPEDVEKDAEA
EVQKIHDKFIKKIDELYAAKEKEVMTV

Sequences:

>Translated_187_residues
MIDTKQLIKAGEEKMTFAIEYLDEQLSHIRAGKANPKILDCVKVMYYGAPVPLTNVATVTVPDARTIMITPWEKKIIRDI
EKGILDSELGITPENNGEVIRLGIPPLTEERRRQLVKQCKQEAENAKISVRNARRDAIEALKKSIKSDGVPEDVEKDAEA
EVQKIHDKFIKKIDELYAAKEKEVMTV
>Mature_187_residues
MIDTKQLIKAGEEKMTFAIEYLDEQLSHIRAGKANPKILDCVKVMYYGAPVPLTNVATVTVPDARTIMITPWEKKIIRDI
EKGILDSELGITPENNGEVIRLGIPPLTEERRRQLVKQCKQEAENAKISVRNARRDAIEALKKSIKSDGVPEDVEKDAEA
EVQKIHDKFIKKIDELYAAKEKEVMTV

Specific function: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another

COG id: COG0233

COG function: function code J; Ribosome recycling factor

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RRF family

Homologues:

Organism=Homo sapiens, GI20270317, Length=174, Percent_Identity=28.1609195402299, Blast_Score=68, Evalue=5e-12,
Organism=Escherichia coli, GI1786368, Length=177, Percent_Identity=42.9378531073446, Blast_Score=149, Evalue=2e-37,
Organism=Saccharomyces cerevisiae, GI6321827, Length=194, Percent_Identity=24.7422680412371, Blast_Score=73, Evalue=3e-14,

Paralogues:

None

Copy number: 840 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): RRF_PARD8 (A6LHB5)

Other databases:

- EMBL:   CP000140
- RefSeq:   YP_001304701.1
- ProteinModelPortal:   A6LHB5
- SMR:   A6LHB5
- STRING:   A6LHB5
- GeneID:   5308525
- GenomeReviews:   CP000140_GR
- KEGG:   pdi:BDI_3376
- eggNOG:   COG0233
- HOGENOM:   HBG533975
- OMA:   YYGAETP
- ProtClustDB:   PRK00083
- BioCyc:   PDIS435591:BDI_3376-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00040
- InterPro:   IPR002661
- InterPro:   IPR015998
- PANTHER:   PTHR20982
- PANTHER:   PTHR20982:SF3
- TIGRFAMs:   TIGR00496

Pfam domain/function: PF01765 RRF; SSF55194 Ribosome_recyc_fac

EC number: NA

Molecular weight: Translated: 21139; Mature: 21139

Theoretical pI: Translated: 6.56; Mature: 6.56

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIDTKQLIKAGEEKMTFAIEYLDEQLSHIRAGKANPKILDCVKVMYYGAPVPLTNVATVT
CCCHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCEEEEE
VPDARTIMITPWEKKIIRDIEKGILDSELGITPENNGEVIRLGIPPLTEERRRQLVKQCK
ECCCCEEEECCHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEECCCCCCHHHHHHHHHHHH
QEAENAKISVRNARRDAIEALKKSIKSDGVPEDVEKDAEAEVQKIHDKFIKKIDELYAAK
HHHHCCEEEHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
EKEVMTV
CCHHCCC
>Mature Secondary Structure
MIDTKQLIKAGEEKMTFAIEYLDEQLSHIRAGKANPKILDCVKVMYYGAPVPLTNVATVT
CCCHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCEEEEE
VPDARTIMITPWEKKIIRDIEKGILDSELGITPENNGEVIRLGIPPLTEERRRQLVKQCK
ECCCCEEEECCHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEECCCCCCHHHHHHHHHHHH
QEAENAKISVRNARRDAIEALKKSIKSDGVPEDVEKDAEAEVQKIHDKFIKKIDELYAAK
HHHHCCEEEHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
EKEVMTV
CCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA