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The map label for this gene is cvrA [H]

Identifier: 150009916

GI number: 150009916

Start: 4035633

End: 4037138

Strand: Direct

Name: cvrA [H]

Synonym: BDI_3333

Alternate gene names: 150009916

Gene position: 4035633-4037138 (Clockwise)

Preceding gene: 150009903

Following gene: 150009924

Centisome position: 83.88

GC content: 46.55

Gene sequence:

>1506_bases
TTGCGTATGTTTCAAAATCCTGAGCAAGTGCTATTAATAGCCTCGGTGATCCTGTTTTTTAGTATATTCGCAGGTAAGGC
CGGTTATCGTTTCGGCTTACCCGCTTTGTTGTTGTTCCTTGGTGTGGGAATGTTGTTTGGCAGCGATGGTCTGGGCATCC
AGTTCAGCGATCCGAATGTAGCCCAGTTTATCGGCATGTTGGCGTTGAGTATCATCTTGTTCTCGGGTGGTATGGACACG
AAAGTTGCGGAGGTCAAACCTATCGCCTCGCAAGGTGTGGTATTGGCTACGCTCGGGGTGTTGGCTACGACCTTTATCAC
GGGCGGGTTTATCTATTGGTTATTTGGTTTATTTGGCAAATATGTTACGTTGACTTTCCCGGAATCTTTATTGCTGGCGG
CGGTCATGTCCTCTACGGACTCAGCCTCGGTTTTCTCCATCTTGCGCAGTAAAGGGGTTTATTTGAAAGAGCGTCTGCGT
CCTACCTTGGAGCTGGAGAGTGGTAGTAATGACCCGATGGCTTATATGCTTACCTTGCTTCTGATCGCTTACATACAAAG
CGGAGGTATGAATATTTGGGAGGCCGGGCTATCCTTGGTCATTCAATTATCGGTGGGAGCTATCGCCGGTTTCTTATTGG
GGAGACTGGCTGTGTTGATTATCAATAAGATCGATATAGATAACGAGTCTTTGTATCCGATCCTTTTATTGGCTACGGCT
TTCTTCACCTTCGCCGCTACGACCTTATGTAAGGGTAATGGCTATTTAGCGGTTTATATCGCTGGTTTGGTGGTTGGTAA
CGCTAAGATTGTTCACAAGAAAAGTATGGGGACGTTCTTTGACGGTTTCGCTTGGTTGTGGCAGATCGTGATGTTCCTTA
CGTTAGGCTTGCTAGTGAACCCGCATGAGTTATTACCGGTGACGGGTGTAGGTGTTATGGTGGGAGTCTTTATGATCTTG
ATCGCCCGTCCGATTAGCGTGTTCCTTTGCTTGATACCTTATAAGAATTTCTCCTTCAAAGGTAAACTGTATATCTCATG
GGTGGGATTACGCGGGGCGGTTCCTATTATTTTCGCTACTTACCCGATGATCGCCGGGATCGAGCATGCCGGTATGTTCT
TTAATATCGTATTTTTTATCACGATTCTTTCTTTGCTGATTCAAGGAACCACGGTTACCCAAGCCGCTAAATGGCTGGAT
ATGGTGGATGAGCCGGAACGAAAGGATGAGTTTGGCATCGAGCTTCCCGAGGAGATCAAGAGCGCTATGAGCGAGATCGA
TATTACCCCGGCGGTATTATCCCATGGAAATAAATTGATGCAGCTGACTTTACCCGATCATACCTTGGCGGTAATGGTGA
AACGGGAAGGCCGCTATTTCATCCCGAAAGGAAATACGGAATTAAAGGAGAACGACAAGTTGTTAATGATCTCCGATAAT
GACGAGGCGCTTTTGCAGGCGTATGATTCCTTGGGGGTGAAGGATTATACGATGAAGAAGAATTGA

Upstream 100 bases:

>100_bases
GTAAATTTGGGACCGGATTTCTTCTTTTTGTGTGATTATAATTGCAAAAAGTTTACGAACTTTGTGACAAAGTATCAAAT
CACTAATCATAAAACCCGTT

Downstream 100 bases:

>100_bases
AATAATGTGCCAATGGGGGAATGTGCCAATATGCCAATGCAGATCTATTTGTGTAGAATAAGCATTGGCATATTGGTACA
TTATTTTTACCGTACCGGAA

Product: potassium/proton antiporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 501; Mature: 501

Protein sequence:

>501_residues
MRMFQNPEQVLLIASVILFFSIFAGKAGYRFGLPALLLFLGVGMLFGSDGLGIQFSDPNVAQFIGMLALSIILFSGGMDT
KVAEVKPIASQGVVLATLGVLATTFITGGFIYWLFGLFGKYVTLTFPESLLLAAVMSSTDSASVFSILRSKGVYLKERLR
PTLELESGSNDPMAYMLTLLLIAYIQSGGMNIWEAGLSLVIQLSVGAIAGFLLGRLAVLIINKIDIDNESLYPILLLATA
FFTFAATTLCKGNGYLAVYIAGLVVGNAKIVHKKSMGTFFDGFAWLWQIVMFLTLGLLVNPHELLPVTGVGVMVGVFMIL
IARPISVFLCLIPYKNFSFKGKLYISWVGLRGAVPIIFATYPMIAGIEHAGMFFNIVFFITILSLLIQGTTVTQAAKWLD
MVDEPERKDEFGIELPEEIKSAMSEIDITPAVLSHGNKLMQLTLPDHTLAVMVKREGRYFIPKGNTELKENDKLLMISDN
DEALLQAYDSLGVKDYTMKKN

Sequences:

>Translated_501_residues
MRMFQNPEQVLLIASVILFFSIFAGKAGYRFGLPALLLFLGVGMLFGSDGLGIQFSDPNVAQFIGMLALSIILFSGGMDT
KVAEVKPIASQGVVLATLGVLATTFITGGFIYWLFGLFGKYVTLTFPESLLLAAVMSSTDSASVFSILRSKGVYLKERLR
PTLELESGSNDPMAYMLTLLLIAYIQSGGMNIWEAGLSLVIQLSVGAIAGFLLGRLAVLIINKIDIDNESLYPILLLATA
FFTFAATTLCKGNGYLAVYIAGLVVGNAKIVHKKSMGTFFDGFAWLWQIVMFLTLGLLVNPHELLPVTGVGVMVGVFMIL
IARPISVFLCLIPYKNFSFKGKLYISWVGLRGAVPIIFATYPMIAGIEHAGMFFNIVFFITILSLLIQGTTVTQAAKWLD
MVDEPERKDEFGIELPEEIKSAMSEIDITPAVLSHGNKLMQLTLPDHTLAVMVKREGRYFIPKGNTELKENDKLLMISDN
DEALLQAYDSLGVKDYTMKKN
>Mature_501_residues
MRMFQNPEQVLLIASVILFFSIFAGKAGYRFGLPALLLFLGVGMLFGSDGLGIQFSDPNVAQFIGMLALSIILFSGGMDT
KVAEVKPIASQGVVLATLGVLATTFITGGFIYWLFGLFGKYVTLTFPESLLLAAVMSSTDSASVFSILRSKGVYLKERLR
PTLELESGSNDPMAYMLTLLLIAYIQSGGMNIWEAGLSLVIQLSVGAIAGFLLGRLAVLIINKIDIDNESLYPILLLATA
FFTFAATTLCKGNGYLAVYIAGLVVGNAKIVHKKSMGTFFDGFAWLWQIVMFLTLGLLVNPHELLPVTGVGVMVGVFMIL
IARPISVFLCLIPYKNFSFKGKLYISWVGLRGAVPIIFATYPMIAGIEHAGMFFNIVFFITILSLLIQGTTVTQAAKWLD
MVDEPERKDEFGIELPEEIKSAMSEIDITPAVLSHGNKLMQLTLPDHTLAVMVKREGRYFIPKGNTELKENDKLLMISDN
DEALLQAYDSLGVKDYTMKKN

Specific function: Participates in control of cell volume in low-osmolarity conditions [H]

COG id: COG3263

COG function: function code P; NhaP-type Na+/H+ and K+/H+ antiporters with a unique C-terminal domain

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 RCK C-terminal domain [H]

Homologues:

Organism=Escherichia coli, GI87081854, Length=455, Percent_Identity=40.8791208791209, Blast_Score=298, Evalue=4e-82,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018421
- InterPro:   IPR006153
- InterPro:   IPR018422
- InterPro:   IPR016169
- InterPro:   IPR006037
- InterPro:   IPR005170 [H]

Pfam domain/function: PF03471 CorC_HlyC; PF00999 Na_H_Exchanger; PF02080 TrkA_C [H]

EC number: NA

Molecular weight: Translated: 54829; Mature: 54829

Theoretical pI: Translated: 6.38; Mature: 6.38

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRMFQNPEQVLLIASVILFFSIFAGKAGYRFGLPALLLFLGVGMLFGSDGLGIQFSDPNV
CCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCCEEEECCCCH
AQFIGMLALSIILFSGGMDTKVAEVKPIASQGVVLATLGVLATTFITGGFIYWLFGLFGK
HHHHHHHHHHHHHHCCCCCCCHHHCCCCHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHC
YVTLTFPESLLLAAVMSSTDSASVFSILRSKGVYLKERLRPTLELESGSNDPMAYMLTLL
EEEEECCHHHHHHHHHCCCCHHHHHHHHHHCCCHHHHHCCCCEEECCCCCCHHHHHHHHH
LIAYIQSGGMNIWEAGLSLVIQLSVGAIAGFLLGRLAVLIINKIDIDNESLYPILLLATA
HHHHHHCCCCHHHHHHHHHEEEHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHH
FFTFAATTLCKGNGYLAVYIAGLVVGNAKIVHKKSMGTFFDGFAWLWQIVMFLTLGLLVN
HHHHHHHHHCCCCCEEEEEEEHHHCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCC
PHELLPVTGVGVMVGVFMILIARPISVFLCLIPYKNFSFKGKLYISWVGLRGAVPIIFAT
CHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEEECCCCCHHHHHH
YPMIAGIEHAGMFFNIVFFITILSLLIQGTTVTQAAKWLDMVDEPERKDEFGIELPEEIK
HHHHHCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCCCCCHHHHH
SAMSEIDITPAVLSHGNKLMQLTLPDHTLAVMVKREGRYFIPKGNTELKENDKLLMISDN
HHHHHCCCCHHHHHCCCEEEEEECCCCEEEEEEEECCCEECCCCCCCCCCCCCEEEEECC
DEALLQAYDSLGVKDYTMKKN
CHHHHHHHHHCCCCCEECCCC
>Mature Secondary Structure
MRMFQNPEQVLLIASVILFFSIFAGKAGYRFGLPALLLFLGVGMLFGSDGLGIQFSDPNV
CCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCCEEEECCCCH
AQFIGMLALSIILFSGGMDTKVAEVKPIASQGVVLATLGVLATTFITGGFIYWLFGLFGK
HHHHHHHHHHHHHHCCCCCCCHHHCCCCHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHC
YVTLTFPESLLLAAVMSSTDSASVFSILRSKGVYLKERLRPTLELESGSNDPMAYMLTLL
EEEEECCHHHHHHHHHCCCCHHHHHHHHHHCCCHHHHHCCCCEEECCCCCCHHHHHHHHH
LIAYIQSGGMNIWEAGLSLVIQLSVGAIAGFLLGRLAVLIINKIDIDNESLYPILLLATA
HHHHHHCCCCHHHHHHHHHEEEHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHH
FFTFAATTLCKGNGYLAVYIAGLVVGNAKIVHKKSMGTFFDGFAWLWQIVMFLTLGLLVN
HHHHHHHHHCCCCCEEEEEEEHHHCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCC
PHELLPVTGVGVMVGVFMILIARPISVFLCLIPYKNFSFKGKLYISWVGLRGAVPIIFAT
CHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEEECCCCCHHHHHH
YPMIAGIEHAGMFFNIVFFITILSLLIQGTTVTQAAKWLDMVDEPERKDEFGIELPEEIK
HHHHHCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCCCCCHHHHH
SAMSEIDITPAVLSHGNKLMQLTLPDHTLAVMVKREGRYFIPKGNTELKENDKLLMISDN
HHHHHCCCCHHHHHCCCEEEEEECCCCEEEEEEEECCCEECCCCCCCCCCCCCEEEEECC
DEALLQAYDSLGVKDYTMKKN
CHHHHHHHHHCCCCCEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA