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The map label for this gene is lolC [H]

Identifier: 150009889

GI number: 150009889

Start: 3998065

End: 3999294

Strand: Direct

Name: lolC [H]

Synonym: BDI_3305

Alternate gene names: 150009889

Gene position: 3998065-3999294 (Clockwise)

Preceding gene: 150009888

Following gene: 150009891

Centisome position: 83.1

GC content: 44.47

Gene sequence:

>1230_bases
TTGAATCTTCCGTTCTATATAGCCCGGCGATATCTCTTTTCGAAGAAGTCGCACAATGCCATAAATATCATATCGATGGT
ATCGGTATGCGGGGTTGTTGTCGCCACGATCGCCTTAGTATGCGCCTTGTCGGTCTATAATGGTTTCAACGATTTGGTAT
CTTCTCTCTTCAGCAATTTTGATCCGGAGTTGAAGATCATGCCCCGGAAAGGGAAGGTTTTCGACCCGACCTCGGAAGAG
ATACGTAAGGTGAGGGAATTGCCCGGCATTGTTTGTTTTAGTGAGGTATTGCAGGACAATGCCTTGGTCCGTTATCGAGA
TCGTCAGGGTGTAGCTACCTTGAAAGGTGTAGACGAGCAATATGAGAAACTGGCGCAGATCGATAGTATCTTGATCGATG
GAAAGTTCCTTCTGAATGACGAGGTAGCGAATTATGCGAATATGGGGATCGGATTGGCTTTCTCGCTAGGAATAAACGCA
GGCTTTGTCTCTCCGCTGGAGATCTACGCTCCGAAGCGGGAGGAGAAGGTGAACATGGCGAATCCGGCTTCTTCTTTCAA
TTTGGAATATGCTTATATCGGTGCTGTCTTTCGTACGGACCAACAGGTTTACGATGATTCATATATGATCGTGCCTTTGT
CATTGGCCCGTTCTTTATTTAATTATGATAAAGAAGTGACAGCGGTGGAATTGAAGGTGAAAGATAGCGGAGATATCGCT
CCGGTAAAGAAAGAGATTCAACGTATCCTAGGTGATCAATATATCGTGCAAGACCGTTTTGAGCAACAAGAGGCTTCTTT
CAAGATGATGCAAGTCGAGAAATGGATGACCTTCTTGATCCTTACTTTTATATTGGCGATCGCCTTATTCAACGTGGTGG
GTTCTTTATCCATGTTGATGATCGAGAAACAGGAGGATGTGAGTACACTGCGTAATATGGGGGCTGATGACAGTCTGATC
CGTCGGATTTTCTTGTTTGAAGGCTGGATGATCTCCGGTTTTGGAGCTTTGATCGGAGTCTTGATCGGGGTTGTACTTTG
CTTGCTACAACAAGAGTTTGGCTTTATAAAACTAGGGGAAGCTGCCGGAGCGTTTATTATAGAGGCTTATCCAGTACGTG
TAGTCACGGTGGATATAATAACAGTCTTTGTAACGGTATTAACGATAGGCTTTTTGGCTGCGTGGTATCCTGTACGATAT
CTTGCTAAGAAGTTGAAAATTGAGAATTGA

Upstream 100 bases:

>100_bases
TGCAGGTTCGTAAGATTCCTGAATTGAGCTTCTTTATAGACGATTCATTGGATTATATCGAGAATATCGACAATCTTTTG
CATAAGTAATCAGAGGAGCC

Downstream 100 bases:

>100_bases
GAATGAATACCGCTTGCCGATAATTCTCAATTCTCAATTCTTAATTAGTTGTATTCTTTTCCGTATTTGATTTTAGCGTC
GGCTACGAATTGTTTGATAC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 409; Mature: 409

Protein sequence:

>409_residues
MNLPFYIARRYLFSKKSHNAINIISMVSVCGVVVATIALVCALSVYNGFNDLVSSLFSNFDPELKIMPRKGKVFDPTSEE
IRKVRELPGIVCFSEVLQDNALVRYRDRQGVATLKGVDEQYEKLAQIDSILIDGKFLLNDEVANYANMGIGLAFSLGINA
GFVSPLEIYAPKREEKVNMANPASSFNLEYAYIGAVFRTDQQVYDDSYMIVPLSLARSLFNYDKEVTAVELKVKDSGDIA
PVKKEIQRILGDQYIVQDRFEQQEASFKMMQVEKWMTFLILTFILAIALFNVVGSLSMLMIEKQEDVSTLRNMGADDSLI
RRIFLFEGWMISGFGALIGVLIGVVLCLLQQEFGFIKLGEAAGAFIIEAYPVRVVTVDIITVFVTVLTIGFLAAWYPVRY
LAKKLKIEN

Sequences:

>Translated_409_residues
MNLPFYIARRYLFSKKSHNAINIISMVSVCGVVVATIALVCALSVYNGFNDLVSSLFSNFDPELKIMPRKGKVFDPTSEE
IRKVRELPGIVCFSEVLQDNALVRYRDRQGVATLKGVDEQYEKLAQIDSILIDGKFLLNDEVANYANMGIGLAFSLGINA
GFVSPLEIYAPKREEKVNMANPASSFNLEYAYIGAVFRTDQQVYDDSYMIVPLSLARSLFNYDKEVTAVELKVKDSGDIA
PVKKEIQRILGDQYIVQDRFEQQEASFKMMQVEKWMTFLILTFILAIALFNVVGSLSMLMIEKQEDVSTLRNMGADDSLI
RRIFLFEGWMISGFGALIGVLIGVVLCLLQQEFGFIKLGEAAGAFIIEAYPVRVVTVDIITVFVTVLTIGFLAAWYPVRY
LAKKLKIEN
>Mature_409_residues
MNLPFYIARRYLFSKKSHNAINIISMVSVCGVVVATIALVCALSVYNGFNDLVSSLFSNFDPELKIMPRKGKVFDPTSEE
IRKVRELPGIVCFSEVLQDNALVRYRDRQGVATLKGVDEQYEKLAQIDSILIDGKFLLNDEVANYANMGIGLAFSLGINA
GFVSPLEIYAPKREEKVNMANPASSFNLEYAYIGAVFRTDQQVYDDSYMIVPLSLARSLFNYDKEVTAVELKVKDSGDIA
PVKKEIQRILGDQYIVQDRFEQQEASFKMMQVEKWMTFLILTFILAIALFNVVGSLSMLMIEKQEDVSTLRNMGADDSLI
RRIFLFEGWMISGFGALIGVLIGVVLCLLQQEFGFIKLGEAAGAFIIEAYPVRVVTVDIITVFVTVLTIGFLAAWYPVRY
LAKKLKIEN

Specific function: Part of an ATP-dependent transport system responsible for the release of lipoproteins targeted to the outer membrane from the inner membrane. Such a release is dependent of the sorting-signal (absence of an Asp at position 2 of the mature lipoprotein) and

COG id: COG4591

COG function: function code M; ABC-type transport system, involved in lipoprotein release, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787362, Length=417, Percent_Identity=24.220623501199, Blast_Score=101, Evalue=9e-23,
Organism=Escherichia coli, GI1787360, Length=335, Percent_Identity=24.1791044776119, Blast_Score=69, Evalue=7e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003838
- InterPro:   IPR011925 [H]

Pfam domain/function: PF02687 FtsX [H]

EC number: NA

Molecular weight: Translated: 45910; Mature: 45910

Theoretical pI: Translated: 5.04; Mature: 5.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLPFYIARRYLFSKKSHNAINIISMVSVCGVVVATIALVCALSVYNGFNDLVSSLFSNF
CCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCC
DPELKIMPRKGKVFDPTSEEIRKVRELPGIVCFSEVLQDNALVRYRDRQGVATLKGVDEQ
CCCEEEECCCCCCCCCCHHHHHHHHHCCCHHHHHHHHCCCCEEEEECCCCCHHHHCCHHH
YEKLAQIDSILIDGKFLLNDEVANYANMGIGLAFSLGINAGFVSPLEIYAPKREEKVNMA
HHHHHHHHHHHCCCEEEECHHHHHHHCCCCCEEEEECCCCCCCCCHHHCCCCCCCCCCCC
NPASSFNLEYAYIGAVFRTDQQVYDDSYMIVPLSLARSLFNYDKEVTAVELKVKDSGDIA
CCCCCCCCEEEEEHHHHHCCHHHHCCCEEEEEHHHHHHHHCCCCCEEEEEEEECCCCCCC
PVKKEIQRILGDQYIVQDRFEQQEASFKMMQVEKWMTFLILTFILAIALFNVVGSLSMLM
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IEKQEDVSTLRNMGADDSLIRRIFLFEGWMISGFGALIGVLIGVVLCLLQQEFGFIKLGE
EECHHHHHHHHHCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECC
AAGAFIIEAYPVRVVTVDIITVFVTVLTIGFLAAWYPVRYLAKKLKIEN
CCCEEEEEECCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MNLPFYIARRYLFSKKSHNAINIISMVSVCGVVVATIALVCALSVYNGFNDLVSSLFSNF
CCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCC
DPELKIMPRKGKVFDPTSEEIRKVRELPGIVCFSEVLQDNALVRYRDRQGVATLKGVDEQ
CCCEEEECCCCCCCCCCHHHHHHHHHCCCHHHHHHHHCCCCEEEEECCCCCHHHHCCHHH
YEKLAQIDSILIDGKFLLNDEVANYANMGIGLAFSLGINAGFVSPLEIYAPKREEKVNMA
HHHHHHHHHHHCCCEEEECHHHHHHHCCCCCEEEEECCCCCCCCCHHHCCCCCCCCCCCC
NPASSFNLEYAYIGAVFRTDQQVYDDSYMIVPLSLARSLFNYDKEVTAVELKVKDSGDIA
CCCCCCCCEEEEEHHHHHCCHHHHCCCEEEEEHHHHHHHHCCCCCEEEEEEEECCCCCCC
PVKKEIQRILGDQYIVQDRFEQQEASFKMMQVEKWMTFLILTFILAIALFNVVGSLSMLM
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IEKQEDVSTLRNMGADDSLIRRIFLFEGWMISGFGALIGVLIGVVLCLLQQEFGFIKLGE
EECHHHHHHHHHCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECC
AAGAFIIEAYPVRVVTVDIITVFVTVLTIGFLAAWYPVRYLAKKLKIEN
CCCEEEEEECCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10761919 [H]