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The map label for this gene is eda [H]

Identifier: 150009770

GI number: 150009770

Start: 3857029

End: 3857703

Strand: Reverse

Name: eda [H]

Synonym: BDI_3185

Alternate gene names: 150009770

Gene position: 3857703-3857029 (Counterclockwise)

Preceding gene: 150009771

Following gene: 150009769

Centisome position: 80.18

GC content: 50.07

Gene sequence:

>675_bases
ATGGCTCAATTCAATAAAATACAAACATTACAGGCTATCATCCAAACCGGAATGGTGCCCGTTTATTATAATAAAGAGGT
AGAGATCGCAAAACAAGTTGTAAAAGCCTGTTACGAGGGAGGCGTCAGAGCCTTCGAGTTTACTAACCGGGGAGATTTCG
CCCACGAGGTATTTGGCGAGCTGGTAAAATACGCCGCCAAGGAATGCCCGGAATTAGTATTGGGCGTAGGTTCTATCGTA
GACCCGGCCACAGCCGCCTTATTCATACAGCTAGGCGCAAACTTCGTAGTCGGCCCGTTGTTCAACCCGGAGATAGCGAA
GATATGTAACCGTCGCCTCATCCCTTATACGCCCGGCTGCGGTTCCGTATCCGAGATCGGCTTTGCCCAAGAAGTTGGTT
GCGACCTTTGCAAGATATTCCCCGCCGGAAATGTAGGAGGTCCCTCATTTGTCAAGAACATAAAGGCACCCATGCCATGG
ACCCTAATCATGGCTACCGGTGCCGTGGAGCCGACAGAGGAGAATCTATCCGCTTGGTTCAAGGCCGGCGTGACCTGCGT
AGGAATGGGATCCAAACTCTTCCCCAAAGAAGCGATAGCGGGAAACGATTGGCAATCCATTACCGATTTATGCCGCAACG
CCTTATCTATCATTCAAAAGTATCGCCAAGTATGA

Upstream 100 bases:

>100_bases
AGTAACCGTAGAGGAAGTAGAAAAACTCATGTCCGGCGACACCTCCGGCCGTGTCTCCCGCTAATTTTCAATTCTCAACT
TTCAATTTTTAATTCCCAAT

Downstream 100 bases:

>100_bases
AAAACTTTTTAGATCAAGATTTCTTGCTCCAAACCGACACGGCCCGTGAGTTATATCACGAGCATGCGGCGAAGATGCCC
ATCATTGATTACCATTGCCA

Product: keto-hydroxyglutarate-aldolase/keto-deoxy- phosphogluconate aldolase

Products: NA

Alternate protein names: KDPG-aldolase; Phospho-2-dehydro-3-deoxygluconate aldolase; Phospho-2-keto-3-deoxygluconate aldolase [H]

Number of amino acids: Translated: 224; Mature: 223

Protein sequence:

>224_residues
MAQFNKIQTLQAIIQTGMVPVYYNKEVEIAKQVVKACYEGGVRAFEFTNRGDFAHEVFGELVKYAAKECPELVLGVGSIV
DPATAALFIQLGANFVVGPLFNPEIAKICNRRLIPYTPGCGSVSEIGFAQEVGCDLCKIFPAGNVGGPSFVKNIKAPMPW
TLIMATGAVEPTEENLSAWFKAGVTCVGMGSKLFPKEAIAGNDWQSITDLCRNALSIIQKYRQV

Sequences:

>Translated_224_residues
MAQFNKIQTLQAIIQTGMVPVYYNKEVEIAKQVVKACYEGGVRAFEFTNRGDFAHEVFGELVKYAAKECPELVLGVGSIV
DPATAALFIQLGANFVVGPLFNPEIAKICNRRLIPYTPGCGSVSEIGFAQEVGCDLCKIFPAGNVGGPSFVKNIKAPMPW
TLIMATGAVEPTEENLSAWFKAGVTCVGMGSKLFPKEAIAGNDWQSITDLCRNALSIIQKYRQV
>Mature_223_residues
AQFNKIQTLQAIIQTGMVPVYYNKEVEIAKQVVKACYEGGVRAFEFTNRGDFAHEVFGELVKYAAKECPELVLGVGSIVD
PATAALFIQLGANFVVGPLFNPEIAKICNRRLIPYTPGCGSVSEIGFAQEVGCDLCKIFPAGNVGGPSFVKNIKAPMPWT
LIMATGAVEPTEENLSAWFKAGVTCVGMGSKLFPKEAIAGNDWQSITDLCRNALSIIQKYRQV

Specific function: KEY ENZYME IN THE ENTNER-DOUDOROFF PATHWAY. PARTICIPATES IN THE REGULATION OF THE INTRACELLULAR LEVEL OF GLYOXYLATE. [C]

COG id: COG0800

COG function: function code G; 2-keto-3-deoxy-6-phosphogluconate aldolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the KHG/KDPG aldolase family [H]

Homologues:

Organism=Escherichia coli, GI1788156, Length=189, Percent_Identity=31.7460317460317, Blast_Score=90, Evalue=1e-19,
Organism=Escherichia coli, GI48994954, Length=156, Percent_Identity=29.4871794871795, Blast_Score=70, Evalue=8e-14,

Paralogues:

None

Copy number: 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000887
- InterPro:   IPR013785 [H]

Pfam domain/function: PF01081 Aldolase [H]

EC number: =4.1.2.14 [H]

Molecular weight: Translated: 24260; Mature: 24129

Theoretical pI: Translated: 6.99; Mature: 6.99

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.6 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
3.6 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAQFNKIQTLQAIIQTGMVPVYYNKEVEIAKQVVKACYEGGVRAFEFTNRGDFAHEVFGE
CCCHHHHHHHHHHHHHCCEEEEECCHHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHH
LVKYAAKECPELVLGVGSIVDPATAALFIQLGANFVVGPLFNPEIAKICNRRLIPYTPGC
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCEEECCCCCHHHHHHHCCCCCCCCCCC
GSVSEIGFAQEVGCDLCKIFPAGNVGGPSFVKNIKAPMPWTLIMATGAVEPTEENLSAWF
CCHHHCCCHHHHCCHHHHHCCCCCCCCHHHHHHCCCCCCEEEEEECCCCCCCHHHHHHHH
KAGVTCVGMGSKLFPKEAIAGNDWQSITDLCRNALSIIQKYRQV
HHCCEEEECCCCCCCHHHCCCCCHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
AQFNKIQTLQAIIQTGMVPVYYNKEVEIAKQVVKACYEGGVRAFEFTNRGDFAHEVFGE
CCHHHHHHHHHHHHHCCEEEEECCHHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHH
LVKYAAKECPELVLGVGSIVDPATAALFIQLGANFVVGPLFNPEIAKICNRRLIPYTPGC
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCEEECCCCCHHHHHHHCCCCCCCCCCC
GSVSEIGFAQEVGCDLCKIFPAGNVGGPSFVKNIKAPMPWTLIMATGAVEPTEENLSAWF
CCHHHCCCHHHHCCHHHHHCCCCCCCCHHHHHHCCCCCCEEEEEECCCCCCCHHHHHHHH
KAGVTCVGMGSKLFPKEAIAGNDWQSITDLCRNALSIIQKYRQV
HHCCEEEECCCCCCCHHHCCCCCHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]