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The map label for this gene is nadA [H]

Identifier: 150009601

GI number: 150009601

Start: 3608754

End: 3609740

Strand: Reverse

Name: nadA [H]

Synonym: BDI_3014

Alternate gene names: 150009601

Gene position: 3609740-3608754 (Counterclockwise)

Preceding gene: 150009603

Following gene: 150009600

Centisome position: 75.03

GC content: 49.34

Gene sequence:

>987_bases
ATGTTGACAAACCAATCAATCGGGTACATGGATGCGCCCGTTCCTAAGGATTTAGACCTTAAGGAAGCGATCGACAAGTT
ACGTAAAGAGAAGAATGCGATTATTTTGGCGCATTACTATCAAACAGGCGATATACAAGATATAGCGGACTATGTGGGAG
ACAGTCTGGCCTTGGCACAATGGGCGGCTAAGACGAAGGCGGATATCATCGTGCTTTGTGGGGTTCACTTTATGGGAGAA
ACGGCGAAGATCCTCTGTCCGGATAAGAAAGTGCTGGTACCGGACTTGAATGCCGGTTGCTCCTTGGCGGATAGTTGTCC
GGCTCCGGAGTTTGCCGAGTTCGTCAAGCAACATCCCGGTCATACGGTAATCTCTTACGTGAATACGACCGCCGCCGTGA
AAGCGGTCACGGATGTGGTGGTTACTTCCACGAACGCCCGCCAGATCGTGGAGAGCTTCCCGGAAGGTACACCGATGATT
TTCGGTCCGGATCGTAACTTAGGTAATTATATCAATAGCATCACGGGACGTAATATGTTGCTTTGGGATGGCGCTTGCCA
CGTGCATGAGCAATTCTCATTGGAGAAGATCTTATCTTTGAAGAAACAGTACCCGAATGCGGAAGTGATCACCCATCCGG
AATGCAAGCAGCCGGTTATACAGGTCTCAGACTTCGTAGGATCGACCGCGGCTTTGCTGAAGCATACCATTAAGTCCGAC
GCGAAACAATTCATTGTAGCGACGGAAAGTGGCGTTATTCACGAGATGCGCAAGCAGAGTCCGGATAAGGAATTCATCCC
GGCTCCTCCGAACGACAGTACTTGCGCTTGCAACGAATGTAATTTCATGCGCTTGAACACGATGGAGAAGCTATATAATT
GCTTGAAGTTCGAGATGCCGGAGATATTCGTGGACGAGGAGGTACAGAAGAAGGCGATCAAACCGATCAAGAAGATGTTG
GAGATCTCTGAGAAGCTGGGACTCTGA

Upstream 100 bases:

>100_bases
ATGAAGATTATCAGTAATACTTTCTGTGGATAATATTGTTTATATATAGTGAAAAGCCTATTGGGAGCAGTAGAAACAGG
AATCATTAATATATAAGGCT

Downstream 100 bases:

>100_bases
TCCAAACAAATGCGGGATAGGTCTCAACCGATAGGCCGGACTTAAATGATATAAAAGCTAAGCCCGGTCTATTATATGTA
AATAATCAAAATTATGTACA

Product: quinolinate synthetase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 328; Mature: 328

Protein sequence:

>328_residues
MLTNQSIGYMDAPVPKDLDLKEAIDKLRKEKNAIILAHYYQTGDIQDIADYVGDSLALAQWAAKTKADIIVLCGVHFMGE
TAKILCPDKKVLVPDLNAGCSLADSCPAPEFAEFVKQHPGHTVISYVNTTAAVKAVTDVVVTSTNARQIVESFPEGTPMI
FGPDRNLGNYINSITGRNMLLWDGACHVHEQFSLEKILSLKKQYPNAEVITHPECKQPVIQVSDFVGSTAALLKHTIKSD
AKQFIVATESGVIHEMRKQSPDKEFIPAPPNDSTCACNECNFMRLNTMEKLYNCLKFEMPEIFVDEEVQKKAIKPIKKML
EISEKLGL

Sequences:

>Translated_328_residues
MLTNQSIGYMDAPVPKDLDLKEAIDKLRKEKNAIILAHYYQTGDIQDIADYVGDSLALAQWAAKTKADIIVLCGVHFMGE
TAKILCPDKKVLVPDLNAGCSLADSCPAPEFAEFVKQHPGHTVISYVNTTAAVKAVTDVVVTSTNARQIVESFPEGTPMI
FGPDRNLGNYINSITGRNMLLWDGACHVHEQFSLEKILSLKKQYPNAEVITHPECKQPVIQVSDFVGSTAALLKHTIKSD
AKQFIVATESGVIHEMRKQSPDKEFIPAPPNDSTCACNECNFMRLNTMEKLYNCLKFEMPEIFVDEEVQKKAIKPIKKML
EISEKLGL
>Mature_328_residues
MLTNQSIGYMDAPVPKDLDLKEAIDKLRKEKNAIILAHYYQTGDIQDIADYVGDSLALAQWAAKTKADIIVLCGVHFMGE
TAKILCPDKKVLVPDLNAGCSLADSCPAPEFAEFVKQHPGHTVISYVNTTAAVKAVTDVVVTSTNARQIVESFPEGTPMI
FGPDRNLGNYINSITGRNMLLWDGACHVHEQFSLEKILSLKKQYPNAEVITHPECKQPVIQVSDFVGSTAALLKHTIKSD
AKQFIVATESGVIHEMRKQSPDKEFIPAPPNDSTCACNECNFMRLNTMEKLYNCLKFEMPEIFVDEEVQKKAIKPIKKML
EISEKLGL

Specific function: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate [H]

COG id: COG0379

COG function: function code H; Quinolinate synthase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the quinolinate synthase A family. Type 2 subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786964, Length=328, Percent_Identity=39.0243902439024, Blast_Score=250, Evalue=7e-68,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003473
- InterPro:   IPR023066 [H]

Pfam domain/function: PF02445 NadA [H]

EC number: =2.5.1.72 [H]

Molecular weight: Translated: 36355; Mature: 36355

Theoretical pI: Translated: 6.05; Mature: 6.05

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
6.1 %Cys+Met (Translated Protein)
3.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
6.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLTNQSIGYMDAPVPKDLDLKEAIDKLRKEKNAIILAHYYQTGDIQDIADYVGDSLALAQ
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCEEEEEEEECCCCHHHHHHHHCCHHHHHH
WAAKTKADIIVLCGVHFMGETAKILCPDKKVLVPDLNAGCSLADSCPAPEFAEFVKQHPG
HHHHCCCCEEEEECCHHCCCCCEEECCCCEEECCCCCCCCCCCCCCCCHHHHHHHHHCCC
HTVISYVNTTAAVKAVTDVVVTSTNARQIVESFPEGTPMIFGPDRNLGNYINSITGRNML
CEEEHHHHHHHHHHHHHHHHEECCCHHHHHHHCCCCCCEEECCCCCHHHHHHHHCCCEEE
LWDGACHVHEQFSLEKILSLKKQYPNAEVITHPECKQPVIQVSDFVGSTAALLKHTIKSD
EECCCHHHHHHHHHHHHHHHHHHCCCCCEEECCCHHCHHHHHHHHHHHHHHHHHHHHHHH
AKQFIVATESGVIHEMRKQSPDKEFIPAPPNDSTCACNECNFMRLNTMEKLYNCLKFEMP
HHHEEEECCCHHHHHHHHCCCCCCCCCCCCCCCCEEECCCCCEEHHHHHHHHHHHHHCCC
EIFVDEEVQKKAIKPIKKMLEISEKLGL
HHHCCHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MLTNQSIGYMDAPVPKDLDLKEAIDKLRKEKNAIILAHYYQTGDIQDIADYVGDSLALAQ
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCEEEEEEEECCCCHHHHHHHHCCHHHHHH
WAAKTKADIIVLCGVHFMGETAKILCPDKKVLVPDLNAGCSLADSCPAPEFAEFVKQHPG
HHHHCCCCEEEEECCHHCCCCCEEECCCCEEECCCCCCCCCCCCCCCCHHHHHHHHHCCC
HTVISYVNTTAAVKAVTDVVVTSTNARQIVESFPEGTPMIFGPDRNLGNYINSITGRNML
CEEEHHHHHHHHHHHHHHHHEECCCHHHHHHHCCCCCCEEECCCCCHHHHHHHHCCCEEE
LWDGACHVHEQFSLEKILSLKKQYPNAEVITHPECKQPVIQVSDFVGSTAALLKHTIKSD
EECCCHHHHHHHHHHHHHHHHHHCCCCCEEECCCHHCHHHHHHHHHHHHHHHHHHHHHHH
AKQFIVATESGVIHEMRKQSPDKEFIPAPPNDSTCACNECNFMRLNTMEKLYNCLKFEMP
HHHEEEECCCHHHHHHHHCCCCCCCCCCCCCCCCEEECCCCCEEHHHHHHHHHHHHHCCC
EIFVDEEVQKKAIKPIKKMLEISEKLGL
HHHCCHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12240834 [H]