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The map label for this gene is dtd

Identifier: 150009555

GI number: 150009555

Start: 3553190

End: 3553642

Strand: Direct

Name: dtd

Synonym: BDI_2968

Alternate gene names: 150009555

Gene position: 3553190-3553642 (Clockwise)

Preceding gene: 150009554

Following gene: 150009556

Centisome position: 73.85

GC content: 44.59

Gene sequence:

>453_bases
ATGAGAACAGTTACACAACGTGTGCAGCACGCTTCCGTCACGATAGACGGACAGCTTAAGTCCAAAATTGGAAAGGGGCT
ATTGGTATTAGTCGGTATCGAGGACAAGGATACGCAAGAAGACATTGAATGGTTGGCAAAAAAGATCACCAACCTACGCA
TATTTGACGATGAAAACGGGGTCATGAACCGCTCGGTTATCGAAGCGGGAGGCGAGATCATGGTTGTCAGCCAATTTACC
TTACACGCCTCTACGAAAAAAGGGAACCGCCCCTCCTACTTAAAAGCGTCTAAACCGGATATCGCCATTCCGATGTATAA
AGCTTTTTGCGAAGAGGTAGGGCTTCAACTCGGAAAACCTGTACAAACCGGAACATTCGGAGCTGATATGAAAATTGAAC
TTTTAAACGACGGGCCGGTTACTATTATTATCGACTCTCAAAATAAAGAATAA

Upstream 100 bases:

>100_bases
CTGAAGTCCGTGATTGGCGAGGCGAAAGCCAAGGCACTACAAGAGGGACTGGATGGAAAGCGAACAGAAAGCGAACAAAA
ATAGAACAAAAGCGAACAAG

Downstream 100 bases:

>100_bases
GTATGGCAGATATAACTTTACAACAAGCCCAGCAAATGGTAGACGCTTGGATCAAGACCTATGGGGTCCGTTATTTCAAT
GAGCTTACCAATATGACCAT

Product: D-tyrosyl-tRNA(Tyr) deacylase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 150; Mature: 150

Protein sequence:

>150_residues
MRTVTQRVQHASVTIDGQLKSKIGKGLLVLVGIEDKDTQEDIEWLAKKITNLRIFDDENGVMNRSVIEAGGEIMVVSQFT
LHASTKKGNRPSYLKASKPDIAIPMYKAFCEEVGLQLGKPVQTGTFGADMKIELLNDGPVTIIIDSQNKE

Sequences:

>Translated_150_residues
MRTVTQRVQHASVTIDGQLKSKIGKGLLVLVGIEDKDTQEDIEWLAKKITNLRIFDDENGVMNRSVIEAGGEIMVVSQFT
LHASTKKGNRPSYLKASKPDIAIPMYKAFCEEVGLQLGKPVQTGTFGADMKIELLNDGPVTIIIDSQNKE
>Mature_150_residues
MRTVTQRVQHASVTIDGQLKSKIGKGLLVLVGIEDKDTQEDIEWLAKKITNLRIFDDENGVMNRSVIEAGGEIMVVSQFT
LHASTKKGNRPSYLKASKPDIAIPMYKAFCEEVGLQLGKPVQTGTFGADMKIELLNDGPVTIIIDSQNKE

Specific function: Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine

COG id: COG1490

COG function: function code J; D-Tyr-tRNAtyr deacylase

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DTD family

Homologues:

Organism=Homo sapiens, GI30795227, Length=149, Percent_Identity=42.9530201342282, Blast_Score=113, Evalue=5e-26,
Organism=Escherichia coli, GI1790320, Length=144, Percent_Identity=45.8333333333333, Blast_Score=131, Evalue=2e-32,
Organism=Caenorhabditis elegans, GI115533292, Length=151, Percent_Identity=39.0728476821192, Blast_Score=107, Evalue=2e-24,
Organism=Saccharomyces cerevisiae, GI6319982, Length=148, Percent_Identity=45.2702702702703, Blast_Score=120, Evalue=6e-29,
Organism=Drosophila melanogaster, GI281361569, Length=147, Percent_Identity=43.5374149659864, Blast_Score=116, Evalue=4e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DTD_PARD8 (A6LG62)

Other databases:

- EMBL:   CP000140
- RefSeq:   YP_001304298.1
- ProteinModelPortal:   A6LG62
- SMR:   A6LG62
- STRING:   A6LG62
- GeneID:   5308117
- GenomeReviews:   CP000140_GR
- KEGG:   pdi:BDI_2968
- eggNOG:   COG1490
- HOGENOM:   HBG286048
- OMA:   MKAVIQR
- ProtClustDB:   PRK05273
- BioCyc:   PDIS435591:BDI_2968-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00518
- InterPro:   IPR003732
- Gene3D:   G3DSA:3.50.80.10
- PANTHER:   PTHR10472
- TIGRFAMs:   TIGR00256

Pfam domain/function: PF02580 Tyr_Deacylase; SSF69500 DTyrtRNA_deacyls

EC number: NA

Molecular weight: Translated: 16515; Mature: 16515

Theoretical pI: Translated: 6.53; Mature: 6.53

Prosite motif: NA

Important sites: ACT_SITE 80-80

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRTVTQRVQHASVTIDGQLKSKIGKGLLVLVGIEDKDTQEDIEWLAKKITNLRIFDDENG
CCCHHHHHHHCEEEECCHHHHCCCCCEEEEEECCCCCCHHHHHHHHHHHCEEEEEECCCC
VMNRSVIEAGGEIMVVSQFTLHASTKKGNRPSYLKASKPDIAIPMYKAFCEEVGLQLGKP
CCCHHHHHCCCCEEEEEEEEEEECCCCCCCCCEEECCCCCEECHHHHHHHHHHHHHCCCC
VQTGTFGADMKIELLNDGPVTIIIDSQNKE
CCCCCCCCCEEEEEECCCCEEEEEECCCCC
>Mature Secondary Structure
MRTVTQRVQHASVTIDGQLKSKIGKGLLVLVGIEDKDTQEDIEWLAKKITNLRIFDDENG
CCCHHHHHHHCEEEECCHHHHCCCCCEEEEEECCCCCCHHHHHHHHHHHCEEEEEECCCC
VMNRSVIEAGGEIMVVSQFTLHASTKKGNRPSYLKASKPDIAIPMYKAFCEEVGLQLGKP
CCCHHHHHCCCCEEEEEEEEEEECCCCCCCCCEEECCCCCEECHHHHHHHHHHHHHCCCC
VQTGTFGADMKIELLNDGPVTIIIDSQNKE
CCCCCCCCCEEEEEECCCCEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA