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The map label for this gene is nanH [H]

Identifier: 150009533

GI number: 150009533

Start: 3525685

End: 3527310

Strand: Direct

Name: nanH [H]

Synonym: BDI_2946

Alternate gene names: 150009533

Gene position: 3525685-3527310 (Clockwise)

Preceding gene: 150009532

Following gene: 150009534

Centisome position: 73.28

GC content: 50.25

Gene sequence:

>1626_bases
ATGAAAAAAACTTTCCTGTATTTCTGCCTTCTTTTCATCGTACAAACGGCTTTTGCGGCAGACAGTATTTATGTGCGAGA
GCAACAAATCCCCATCTTGATAGACCGGATCGACAATGTACTTTACGAGATGCGGATACCGGCCCAAAAAGGGGATGTAT
TAAACGAGATCACGATACAGATCGGAGACAATGTCGACCTGTCGGACATCCAAGCGATACGTCTATTTTATAGCGGAGTG
GAAGCTCCTTCCCGCAAAGGGGAACATTTCAGTCCCGTTACGTACATATCCAGCCATATACCGGGAAATACCCGTAAGGC
TCTTGAATCTTATTCCGTACGGCAAGATGAGGTTACCGCCCCCTTGTCGCGCACGGTAAAACTAACCTCTAAGCAACCGA
TGCTTAAAGGCATCAACTATTTCTGGGTAAGTATCCAGATGAAGCCTGAGACTTCCTTATTGGCAAAAGTAGCGACCACG
ATGCCTAACGCCCAGATCAACAACAAACCGATCAACATCACTTGGAAAGGAAAGGTGGACGAACGCCATGTAGGTATCGG
CGTACGCCAAGCCGGGGATGACGGATCGGCGGCCTTCCGCATCCCGGGATTAGTGACGACGAATAACGGAACATTACTCG
GAGTCTACGATATTCGCTATAATAGCAGCGTGGACCTGCAAGAGAAAATCGATATCGGAGTAAGCCGCAGTACCGATAAG
GGACAAACTTGGGAACCGATGCGAGTAGCCATGACTTTCAAACAAACGGATGGCCTGCCCCACGGACAAAACGGCGTGGG
AGACCCATCGATCTTGGTAGACGAAAAGACCAATACGATCTGGGTAGTAGCCGCATGGACGCATGGTATGGGTAACGAAC
GGGCTTGGTGGAACTCCATGCCGGGAATGACACCGGACGAGACCGCCCAACTTATGCTCGTGAAAAGTGAGGACGATGGT
AAGACGTGGAGCGAACCGATCAACATCACGTCTCAAGTAAAAGACCCGTCTTGGTATTTCTTATTGCAAGGCCCGGGACG
AGGCATCACGATGCAAGACGGTACTTTGGTCTTCCCCATCCAGTTTATCGACGCTACCCGTGTGCCGAACGCCGGTATCA
TGTATAGCAAAGACCGAGGGAAAACATGGCATCTACACAACTTGGCCCGCACGAATACCACCGAGGCGCAAGTTGCCGAG
GTAGAACCGGGCGTATTGATGCTAAATATGCGCGATAACCGAGGCGGTAGCCGTGCCGTAGCCACTACAAAGGATTTAGG
CAAGACATGGACGGAGCATCCTTCCAGCCGTAGCGCCTTACAGGAATCCGTTTGTATGGCCAGCTTGATCAAGGTAAACG
CCAAGGATAACATCACCGGCAAGGACCTTCTACTCTTCTCCAACCCGAACACGACGAAAGGGCGTAATCATATCACGATC
AAGGCGAGTCTGGACGGTGGACTTACTTGGCCCACGGAGCATCAAGTCTTATTAGACGAGGCCGAGGGGTGGGGATATTC
CTGTCTTTCGATGATCGATAAGGAAACGGTAGGAATCTTCTACGAGTCAAGCGTAGCGCATATGACCTTCCAAGCTGTCA
AATTACAGGATCTCATTCATCAATAA

Upstream 100 bases:

>100_bases
TTTTGGCACGAATTCCAAAGGGGCTTTGTTCATATGAATGAATATCGCTACCTTTGGAATTCACATATCTATTAATTTCA
ACCTACAAACAAAAAACATC

Downstream 100 bases:

>100_bases
TCTAAGTATATGCGATATATACTGCATTTTGCAATTGTTTTAAGTTTCTTGTATTCCGGGCCTCTGATGGCCCGGAATCC
TGTTTTATTGCCCTTGCCCC

Product: sialidase

Products: NA

Alternate protein names: Neuraminidase [H]

Number of amino acids: Translated: 541; Mature: 541

Protein sequence:

>541_residues
MKKTFLYFCLLFIVQTAFAADSIYVREQQIPILIDRIDNVLYEMRIPAQKGDVLNEITIQIGDNVDLSDIQAIRLFYSGV
EAPSRKGEHFSPVTYISSHIPGNTRKALESYSVRQDEVTAPLSRTVKLTSKQPMLKGINYFWVSIQMKPETSLLAKVATT
MPNAQINNKPINITWKGKVDERHVGIGVRQAGDDGSAAFRIPGLVTTNNGTLLGVYDIRYNSSVDLQEKIDIGVSRSTDK
GQTWEPMRVAMTFKQTDGLPHGQNGVGDPSILVDEKTNTIWVVAAWTHGMGNERAWWNSMPGMTPDETAQLMLVKSEDDG
KTWSEPINITSQVKDPSWYFLLQGPGRGITMQDGTLVFPIQFIDATRVPNAGIMYSKDRGKTWHLHNLARTNTTEAQVAE
VEPGVLMLNMRDNRGGSRAVATTKDLGKTWTEHPSSRSALQESVCMASLIKVNAKDNITGKDLLLFSNPNTTKGRNHITI
KASLDGGLTWPTEHQVLLDEAEGWGYSCLSMIDKETVGIFYESSVAHMTFQAVKLQDLIHQ

Sequences:

>Translated_541_residues
MKKTFLYFCLLFIVQTAFAADSIYVREQQIPILIDRIDNVLYEMRIPAQKGDVLNEITIQIGDNVDLSDIQAIRLFYSGV
EAPSRKGEHFSPVTYISSHIPGNTRKALESYSVRQDEVTAPLSRTVKLTSKQPMLKGINYFWVSIQMKPETSLLAKVATT
MPNAQINNKPINITWKGKVDERHVGIGVRQAGDDGSAAFRIPGLVTTNNGTLLGVYDIRYNSSVDLQEKIDIGVSRSTDK
GQTWEPMRVAMTFKQTDGLPHGQNGVGDPSILVDEKTNTIWVVAAWTHGMGNERAWWNSMPGMTPDETAQLMLVKSEDDG
KTWSEPINITSQVKDPSWYFLLQGPGRGITMQDGTLVFPIQFIDATRVPNAGIMYSKDRGKTWHLHNLARTNTTEAQVAE
VEPGVLMLNMRDNRGGSRAVATTKDLGKTWTEHPSSRSALQESVCMASLIKVNAKDNITGKDLLLFSNPNTTKGRNHITI
KASLDGGLTWPTEHQVLLDEAEGWGYSCLSMIDKETVGIFYESSVAHMTFQAVKLQDLIHQ
>Mature_541_residues
MKKTFLYFCLLFIVQTAFAADSIYVREQQIPILIDRIDNVLYEMRIPAQKGDVLNEITIQIGDNVDLSDIQAIRLFYSGV
EAPSRKGEHFSPVTYISSHIPGNTRKALESYSVRQDEVTAPLSRTVKLTSKQPMLKGINYFWVSIQMKPETSLLAKVATT
MPNAQINNKPINITWKGKVDERHVGIGVRQAGDDGSAAFRIPGLVTTNNGTLLGVYDIRYNSSVDLQEKIDIGVSRSTDK
GQTWEPMRVAMTFKQTDGLPHGQNGVGDPSILVDEKTNTIWVVAAWTHGMGNERAWWNSMPGMTPDETAQLMLVKSEDDG
KTWSEPINITSQVKDPSWYFLLQGPGRGITMQDGTLVFPIQFIDATRVPNAGIMYSKDRGKTWHLHNLARTNTTEAQVAE
VEPGVLMLNMRDNRGGSRAVATTKDLGKTWTEHPSSRSALQESVCMASLIKVNAKDNITGKDLLLFSNPNTTKGRNHITI
KASLDGGLTWPTEHQVLLDEAEGWGYSCLSMIDKETVGIFYESSVAHMTFQAVKLQDLIHQ

Specific function: Sialidases have been suggested to be pathogenic factors in microbial infections [H]

COG id: COG4409

COG function: function code G; Neuraminidase (sialidase)

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 5 BNR repeats [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002860
- InterPro:   IPR011040
- InterPro:   IPR008377 [H]

Pfam domain/function: PF02012 BNR [H]

EC number: =3.2.1.18 [H]

Molecular weight: Translated: 60191; Mature: 60191

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKTFLYFCLLFIVQTAFAADSIYVREQQIPILIDRIDNVLYEMRIPAQKGDVLNEITIQ
CCCHHHHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHEEEECCCCCCCCEEEEEEE
IGDNVDLSDIQAIRLFYSGVEAPSRKGEHFSPVTYISSHIPGNTRKALESYSVRQDEVTA
ECCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHCCCCCHHHHHHHCCCCCHHHCC
PLSRTVKLTSKQPMLKGINYFWVSIQMKPETSLLAKVATTMPNAQINNKPINITWKGKVD
CHHHEEEECCCCCHHCCCEEEEEEEEECCCHHHHHHHHHHCCCCEECCCCEEEEECCCCC
ERHVGIGVRQAGDDGSAAFRIPGLVTTNNGTLLGVYDIRYNSSVDLQEKIDIGVSRSTDK
CEEECEEEEECCCCCCEEEEECEEEECCCCEEEEEEEEEECCCCCHHHHHCCCCCCCCCC
GQTWEPMRVAMTFKQTDGLPHGQNGVGDPSILVDEKTNTIWVVAAWTHGMGNERAWWNSM
CCCCCCEEEEEEEECCCCCCCCCCCCCCCCEEEECCCCEEEEEEEEECCCCCCCCHHCCC
PGMTPDETAQLMLVKSEDDGKTWSEPINITSQVKDPSWYFLLQGPGRGITMQDGTLVFPI
CCCCCCCCEEEEEEEECCCCCCCCCCCCCEEECCCCCEEEEEECCCCEEEEECCEEEEEE
QFIDATRVPNAGIMYSKDRGKTWHLHNLARTNTTEAQVAEVEPGVLMLNMRDNRGGSRAV
EEEECCCCCCCCEEEECCCCCEEEEECCCCCCCCCEEEEECCCCEEEEEEECCCCCCEEE
ATTKDLGKTWTEHPSSRSALQESVCMASLIKVNAKDNITGKDLLLFSNPNTTKGRNHITI
EECHHHHHHHHCCCCHHHHHHHHHHHHHHHEECCCCCCCCCEEEEECCCCCCCCCEEEEE
KASLDGGLTWPTEHQVLLDEAEGWGYSCLSMIDKETVGIFYESSVAHMTFQAVKLQDLIH
EEECCCCCCCCCCCEEEEECCCCCCHHHHHHHCCCCEEEEEECCEEEHHHHHHHHHHHHC
Q
C
>Mature Secondary Structure
MKKTFLYFCLLFIVQTAFAADSIYVREQQIPILIDRIDNVLYEMRIPAQKGDVLNEITIQ
CCCHHHHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHEEEECCCCCCCCEEEEEEE
IGDNVDLSDIQAIRLFYSGVEAPSRKGEHFSPVTYISSHIPGNTRKALESYSVRQDEVTA
ECCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHCCCCCHHHHHHHCCCCCHHHCC
PLSRTVKLTSKQPMLKGINYFWVSIQMKPETSLLAKVATTMPNAQINNKPINITWKGKVD
CHHHEEEECCCCCHHCCCEEEEEEEEECCCHHHHHHHHHHCCCCEECCCCEEEEECCCCC
ERHVGIGVRQAGDDGSAAFRIPGLVTTNNGTLLGVYDIRYNSSVDLQEKIDIGVSRSTDK
CEEECEEEEECCCCCCEEEEECEEEECCCCEEEEEEEEEECCCCCHHHHHCCCCCCCCCC
GQTWEPMRVAMTFKQTDGLPHGQNGVGDPSILVDEKTNTIWVVAAWTHGMGNERAWWNSM
CCCCCCEEEEEEEECCCCCCCCCCCCCCCCEEEECCCCEEEEEEEEECCCCCCCCHHCCC
PGMTPDETAQLMLVKSEDDGKTWSEPINITSQVKDPSWYFLLQGPGRGITMQDGTLVFPI
CCCCCCCCEEEEEEEECCCCCCCCCCCCCEEECCCCCEEEEEECCCCEEEEECCEEEEEE
QFIDATRVPNAGIMYSKDRGKTWHLHNLARTNTTEAQVAEVEPGVLMLNMRDNRGGSRAV
EEEECCCCCCCCEEEECCCCCEEEEECCCCCCCCCEEEEECCCCEEEEEEECCCCCCEEE
ATTKDLGKTWTEHPSSRSALQESVCMASLIKVNAKDNITGKDLLLFSNPNTTKGRNHITI
EECHHHHHHHHCCCCHHHHHHHHHHHHHHHEECCCCCCCCCEEEEECCCCCCCCCEEEEE
KASLDGGLTWPTEHQVLLDEAEGWGYSCLSMIDKETVGIFYESSVAHMTFQAVKLQDLIH
EEECCCCCCCCCCCEEEEECCCCCCHHHHHHHCCCCEEEEEECCEEEHHHHHHHHHHHHC
Q
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8093075; 2158974 [H]