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The map label for this gene is xylR [H]

Identifier: 150009465

GI number: 150009465

Start: 3428992

End: 3429918

Strand: Direct

Name: xylR [H]

Synonym: BDI_2878

Alternate gene names: 150009465

Gene position: 3428992-3429918 (Clockwise)

Preceding gene: 150009464

Following gene: 150009466

Centisome position: 71.27

GC content: 48.11

Gene sequence:

>927_bases
ATGAAATACGCTATCGCATTAGACATTGGAGGAACAAGCATAAAATATACTCTTGTGAACCAGAATGGCGACATTCTTTA
CGAATCGTCGGAAACCACACAATCAAAAGAGAATCCACGCCCATTATCCGATACCATAAAAAGTATCGTACGGAAAATGA
CAGACTACGCCCGTTCCCGGGACTGGGGGATTTACGGAATTGGCATAGGTGTACCTTCCGTAGTAGATAAGGGGGTGGTT
CTCTTTGCCAATAATCTTCCTGAACTGGACAACCAACAATTGGATCTTGCGTTAGCGGAATTTAATCTACCGGTATTCAT
CGACAACGACGCAAACCTTATGGGGTTGGGCGAGGTGATATATGGGGCGGCTAAGGGCCTCTCCGATATCGTTTTCTTGA
CGGTGGGTACCGGCATAGGGGGCGCCTTGTTCTTGAACGGCCGGCTTTATGGCGGCTACCGGAACCGGGGCACCGAACTT
GGGCACTTAATTATTCATGGTCTGAATGGGAATCAATGTACTTGCGGAGCGTCCGGTTGCCTAGAGGCACACGCTTCCGT
AAGTGCGTTGATCGCCTTATATCGGCAATTATTGGAGAAGAACGGACGGGAGATACCTTCCCGTATCGATGGAAAATATA
TAGTAGAGCGCTATAAAGCTCAAGAGAAAGAGGCCGTACTCGCTATGGAGGATCATTTCCGGAATCTGTCCCTAGGCGTA
GCGAGCCTTATCAACATTTTCGCTCCGCAAAAGGTGATTATCGGCGGAGGCATTTCGGAATCCGGAGATTTCTACATTAA
TAATATACGGGAACAGGTCTGGAAATTCGTGATGAAGGAAACCTCGTACTTCACGACTATCGAACTTGCCCGATTAGGAA
ATAAGGCCGGATGCCTCGGGGCGGCGGCATTGGTGTTTAATCATTGA

Upstream 100 bases:

>100_bases
GACGGAGTTGCCGGCCTCCTTATTGTGGCTGCACCCGAACGTGATTTGCCTGATCGACAGGGAAGCGGCGCATAGTTCTA
ATTAAGCTTTTACAATTATC

Downstream 100 bases:

>100_bases
ATCTATCTATCATGAATAAGAATAATTGGATCGTACTCCTCATCTTGTGTATTTGGTTTGTCATTTCTTTTGTTACCAAT
ATATTAGGCCCTATGCTACC

Product: ROK family transcriptional repressor

Products: ADP; D-glucose 6-phosphate

Alternate protein names: NA

Number of amino acids: Translated: 308; Mature: 308

Protein sequence:

>308_residues
MKYAIALDIGGTSIKYTLVNQNGDILYESSETTQSKENPRPLSDTIKSIVRKMTDYARSRDWGIYGIGIGVPSVVDKGVV
LFANNLPELDNQQLDLALAEFNLPVFIDNDANLMGLGEVIYGAAKGLSDIVFLTVGTGIGGALFLNGRLYGGYRNRGTEL
GHLIIHGLNGNQCTCGASGCLEAHASVSALIALYRQLLEKNGREIPSRIDGKYIVERYKAQEKEAVLAMEDHFRNLSLGV
ASLINIFAPQKVIIGGGISESGDFYINNIREQVWKFVMKETSYFTTIELARLGNKAGCLGAAALVFNH

Sequences:

>Translated_308_residues
MKYAIALDIGGTSIKYTLVNQNGDILYESSETTQSKENPRPLSDTIKSIVRKMTDYARSRDWGIYGIGIGVPSVVDKGVV
LFANNLPELDNQQLDLALAEFNLPVFIDNDANLMGLGEVIYGAAKGLSDIVFLTVGTGIGGALFLNGRLYGGYRNRGTEL
GHLIIHGLNGNQCTCGASGCLEAHASVSALIALYRQLLEKNGREIPSRIDGKYIVERYKAQEKEAVLAMEDHFRNLSLGV
ASLINIFAPQKVIIGGGISESGDFYINNIREQVWKFVMKETSYFTTIELARLGNKAGCLGAAALVFNH
>Mature_308_residues
MKYAIALDIGGTSIKYTLVNQNGDILYESSETTQSKENPRPLSDTIKSIVRKMTDYARSRDWGIYGIGIGVPSVVDKGVV
LFANNLPELDNQQLDLALAEFNLPVFIDNDANLMGLGEVIYGAAKGLSDIVFLTVGTGIGGALFLNGRLYGGYRNRGTEL
GHLIIHGLNGNQCTCGASGCLEAHASVSALIALYRQLLEKNGREIPSRIDGKYIVERYKAQEKEAVLAMEDHFRNLSLGV
ASLINIFAPQKVIIGGGISESGDFYINNIREQVWKFVMKETSYFTTIELARLGNKAGCLGAAALVFNH

Specific function: Transcriptional repressor of xylose-utilizing enzymes [H]

COG id: COG1940

COG function: function code KG; Transcriptional regulator/sugar kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ROK (nagC/xylR) family [H]

Homologues:

Organism=Homo sapiens, GI298566315, Length=284, Percent_Identity=28.8732394366197, Blast_Score=93, Evalue=3e-19,
Organism=Homo sapiens, GI298566325, Length=284, Percent_Identity=28.8732394366197, Blast_Score=93, Evalue=3e-19,
Organism=Homo sapiens, GI4885285, Length=286, Percent_Identity=28.6713286713287, Blast_Score=93, Evalue=3e-19,
Organism=Homo sapiens, GI190014632, Length=286, Percent_Identity=28.6713286713287, Blast_Score=92, Evalue=4e-19,
Organism=Escherichia coli, GI87081733, Length=311, Percent_Identity=27.3311897106109, Blast_Score=96, Evalue=4e-21,
Organism=Escherichia coli, GI1787878, Length=314, Percent_Identity=23.2484076433121, Blast_Score=88, Evalue=6e-19,
Organism=Escherichia coli, GI1787363, Length=310, Percent_Identity=26.7741935483871, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1786891, Length=315, Percent_Identity=27.3015873015873, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI1790522, Length=284, Percent_Identity=26.7605633802817, Blast_Score=85, Evalue=5e-18,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000835
- InterPro:   IPR000600
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01047 MarR; PF00480 ROK [H]

EC number: 2.7.1.2

Molecular weight: Translated: 33487; Mature: 33487

Theoretical pI: Translated: 6.36; Mature: 6.36

Prosite motif: PS01125 ROK

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKYAIALDIGGTSIKYTLVNQNGDILYESSETTQSKENPRPLSDTIKSIVRKMTDYARSR
CCEEEEEEECCCEEEEEEEECCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCC
DWGIYGIGIGVPSVVDKGVVLFANNLPELDNQQLDLALAEFNLPVFIDNDANLMGLGEVI
CCCEEEECCCCHHHHCCCEEEEECCCCCCCCCCEEEEEEECCCCEEECCCCCEEEHHHHH
YGAAKGLSDIVFLTVGTGIGGALFLNGRLYGGYRNRGTELGHLIIHGLNGNQCTCGASGC
HHHHCCCCEEEEEEECCCCCEEEEECCEEECCCCCCCCEEEEEEEECCCCCEEECCCCHH
LEAHASVSALIALYRQLLEKNGREIPSRIDGKYIVERYKAQEKEAVLAMEDHFRNLSLGV
HHHHHHHHHHHHHHHHHHHCCCCCCCHHCCCHHHHHHHHHHHHHHEEEHHHHHHHHHHHH
ASLINIFAPQKVIIGGGISESGDFYINNIREQVWKFVMKETSYFTTIELARLGNKAGCLG
HHHHHHHCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHCCCHHEEEEHHHCCCCCCHHH
AAALVFNH
HHHHEECC
>Mature Secondary Structure
MKYAIALDIGGTSIKYTLVNQNGDILYESSETTQSKENPRPLSDTIKSIVRKMTDYARSR
CCEEEEEEECCCEEEEEEEECCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCC
DWGIYGIGIGVPSVVDKGVVLFANNLPELDNQQLDLALAEFNLPVFIDNDANLMGLGEVI
CCCEEEECCCCHHHHCCCEEEEECCCCCCCCCCEEEEEEECCCCEEECCCCCEEEHHHHH
YGAAKGLSDIVFLTVGTGIGGALFLNGRLYGGYRNRGTELGHLIIHGLNGNQCTCGASGC
HHHHCCCCEEEEEEECCCCCEEEEECCEEECCCCCCCCEEEEEEEECCCCCEEECCCCHH
LEAHASVSALIALYRQLLEKNGREIPSRIDGKYIVERYKAQEKEAVLAMEDHFRNLSLGV
HHHHHHHHHHHHHHHHHHHCCCCCCCHHCCCHHHHHHHHHHHHHHEEEHHHHHHHHHHHH
ASLINIFAPQKVIIGGGISESGDFYINNIREQVWKFVMKETSYFTTIELARLGNKAGCLG
HHHHHHHCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHCCCHHEEEEHHHCCCCCCHHH
AAALVFNH
HHHHEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; D-glucose

Specific reaction: ATP + D-glucose = ADP + D-glucose 6-phosphate

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8920183 [H]