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The map label for this gene is ispD [H]

Identifier: 150009298

GI number: 150009298

Start: 3208301

End: 3208999

Strand: Reverse

Name: ispD [H]

Synonym: BDI_2700

Alternate gene names: 150009298

Gene position: 3208999-3208301 (Counterclockwise)

Preceding gene: 150009299

Following gene: 150009297

Centisome position: 66.7

GC content: 51.5

Gene sequence:

>699_bases
ATGGATAAGTACGTCTTGATCGTTGCCGGGGGTAAAGGGCTTCGTATGGGTGGAGATCTGCCGAAGCAGTTTATTCCTAT
GCGGGGGAAACCTCTTTTGATGCATACCTTAGAGGCTTTTCATCGTTGGGATGCTTCCGCACGTATAATCCTTGTGCTTC
CGGAGGATCATCAGCCGTATTGGAATATGCTTTGCAAGGAAATCGGCTGCAAGGTCCCGCATGCGATCGTGAAAGGGGGA
GATACTCGCTTCTTCTCGGTTAAGAATGGGTTGGATTGGCTTTTGGCGGAGAGGCGTCGGAAGGGGGAGGAGGATAGCGG
TCTGAGTTTGGTCGCTGTGCACGATGGCGTTCGTCCTTTCGTCTCTCCGGAGGTTGTTGAGGCCTGCTTTGATAAAGCGG
CTGTCACGGGAGCCGTTATCCCGGTTGTTCCGATGATTGATTCCCTGCGTGAGACAGATGAAAAAGGGAGCCATCCGGTG
GACCGTTCCCGCTATATGGCTGTACAAACCCCGCAAGTCTTCCTTCTGGAATTATTGACAAAAGCCTATGAGCAACCTTA
TTCGTCTTTATTTACGGACGACGCTTCCGTGGTGGAGGCGATGGGGCATGCGATTGATACGGTTCCCGGTGATCGTGAGA
ATATCAAGATTACCACGCCCTTTGATTTGTTAATAGCGGAAGCGATGTTTGCCCGGTAA

Upstream 100 bases:

>100_bases
CCGAGAAGGTAAAAGAAGCTACCCGTCTGATCAAGCTCTGCAAGGAGAAGCTGTATAAAGTGGATGAGGAAGTTAAAAAA
GTTTTGGAGGAATTGGATTG

Downstream 100 bases:

>100_bases
ACCCTAAAAACTCATAGACGTTATGCTGGACCTTGATAAGCGATCGATTACGTACTTGCCGGGAGTAGGACCCAAGAAGG
CGGATATCCTGCAAAAGGAA

Product: 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase

Products: NA

Alternate protein names: 4-diphosphocytidyl-2C-methyl-D-erythritol synthase; MEP cytidylyltransferase; MCT [H]

Number of amino acids: Translated: 232; Mature: 232

Protein sequence:

>232_residues
MDKYVLIVAGGKGLRMGGDLPKQFIPMRGKPLLMHTLEAFHRWDASARIILVLPEDHQPYWNMLCKEIGCKVPHAIVKGG
DTRFFSVKNGLDWLLAERRRKGEEDSGLSLVAVHDGVRPFVSPEVVEACFDKAAVTGAVIPVVPMIDSLRETDEKGSHPV
DRSRYMAVQTPQVFLLELLTKAYEQPYSSLFTDDASVVEAMGHAIDTVPGDRENIKITTPFDLLIAEAMFAR

Sequences:

>Translated_232_residues
MDKYVLIVAGGKGLRMGGDLPKQFIPMRGKPLLMHTLEAFHRWDASARIILVLPEDHQPYWNMLCKEIGCKVPHAIVKGG
DTRFFSVKNGLDWLLAERRRKGEEDSGLSLVAVHDGVRPFVSPEVVEACFDKAAVTGAVIPVVPMIDSLRETDEKGSHPV
DRSRYMAVQTPQVFLLELLTKAYEQPYSSLFTDDASVVEAMGHAIDTVPGDRENIKITTPFDLLIAEAMFAR
>Mature_232_residues
MDKYVLIVAGGKGLRMGGDLPKQFIPMRGKPLLMHTLEAFHRWDASARIILVLPEDHQPYWNMLCKEIGCKVPHAIVKGG
DTRFFSVKNGLDWLLAERRRKGEEDSGLSLVAVHDGVRPFVSPEVVEACFDKAAVTGAVIPVVPMIDSLRETDEKGSHPV
DRSRYMAVQTPQVFLLELLTKAYEQPYSSLFTDDASVVEAMGHAIDTVPGDRENIKITTPFDLLIAEAMFAR

Specific function: Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) [H]

COG id: COG1211

COG function: function code I; 4-diphosphocytidyl-2-methyl-D-erithritol synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ispD family [H]

Homologues:

Organism=Homo sapiens, GI157412259, Length=186, Percent_Identity=32.7956989247312, Blast_Score=81, Evalue=7e-16,
Organism=Escherichia coli, GI1789104, Length=241, Percent_Identity=26.9709543568465, Blast_Score=70, Evalue=8e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001228 [H]

Pfam domain/function: PF01128 IspD [H]

EC number: =2.7.7.60 [H]

Molecular weight: Translated: 25818; Mature: 25818

Theoretical pI: Translated: 6.16; Mature: 6.16

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDKYVLIVAGGKGLRMGGDLPKQFIPMRGKPLLMHTLEAFHRWDASARIILVLPEDHQPY
CCCEEEEEECCCCCCCCCCCCHHHCCCCCCHHHHHHHHHHHHCCCCCEEEEEECCCCCHH
WNMLCKEIGCKVPHAIVKGGDTRFFSVKNGLDWLLAERRRKGEEDSGLSLVAVHDGVRPF
HHHHHHHHCCCCCHHHHCCCCEEEEEECCCHHHHHHHHHHCCCCCCCEEEEEEECCCCCC
VSPEVVEACFDKAAVTGAVIPVVPMIDSLRETDEKGSHPVDRSRYMAVQTPQVFLLELLT
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCHHHHHHHHHH
KAYEQPYSSLFTDDASVVEAMGHAIDTVPGDRENIKITTPFDLLIAEAMFAR
HHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCEEEECHHHHHHHHHHHCC
>Mature Secondary Structure
MDKYVLIVAGGKGLRMGGDLPKQFIPMRGKPLLMHTLEAFHRWDASARIILVLPEDHQPY
CCCEEEEEECCCCCCCCCCCCHHHCCCCCCHHHHHHHHHHHHCCCCCEEEEEECCCCCHH
WNMLCKEIGCKVPHAIVKGGDTRFFSVKNGLDWLLAERRRKGEEDSGLSLVAVHDGVRPF
HHHHHHHHCCCCCHHHHCCCCEEEEEECCCHHHHHHHHHHCCCCCCCEEEEEEECCCCCC
VSPEVVEACFDKAAVTGAVIPVVPMIDSLRETDEKGSHPVDRSRYMAVQTPQVFLLELLT
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCHHHHHHHHHH
KAYEQPYSSLFTDDASVVEAMGHAIDTVPGDRENIKITTPFDLLIAEAMFAR
HHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCEEEECHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA