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The map label for this gene is appC [H]

Identifier: 150009246

GI number: 150009246

Start: 3128603

End: 3130159

Strand: Direct

Name: appC [H]

Synonym: BDI_2648

Alternate gene names: 150009246

Gene position: 3128603-3130159 (Clockwise)

Preceding gene: 150009238

Following gene: 150009247

Centisome position: 65.03

GC content: 45.86

Gene sequence:

>1557_bases
ATGATTGAAAACATTGACACTTCATTGATCGATTGGTCGAGGGCCCAATTTGCCCTTACGGCCATGTATCATTGGCTCTT
CGTGCCACTAACACTAGGACTTGGCGTTATCCAAGCTATTATGGAGACGATTTATTATCGGACAGGTAATGAGGCATGGA
AAAAGACCGCCCAATTTTGGATGAAATTATTCGGTATCAATTTCGCTATCGGTGTCGCTACGGGATTGATCCTCGAGTTC
GAGTTTGGAACCAACTGGTCTAACTATAGTTGGTTTGTAGGGGATATCTTCGGGGCACCTTTGGCTATCGAGGGAATTCT
CGCCTTCTTTATGGAAGCCACCTTTATCGCTGTTATGTTTTTTGGTTGGGACAAAGTTAGCAAACGCTTCCATCTCGCCT
CCACTTGGCTGACGATTATCGGCGCTACTCTTTCCGCCCTCTGGATCTTGATCGCTAACGCATGGATGCAATATCCGGTC
GGTATGCATTTCAATCCGGATACGGTCCGTAACGAGATGTTCGATTTCTGGGCCGTAGCTTTATCGCCTGTCGCCATTAA
TAAGTTTTTCCATACGGTATTGTCCGGTTGGATCGTAGGCGCCTTGTTCGTACTAGGAATCAGCTGCTGGTATTTATTAA
AGAAACGGAATACCGAATTCGCTTTGTCAAGTATCAAGGTCAGCGCTATATTCGGGTTGGTAGCCTCCATCCTTATTATC
TGGACGGGTGATGGCTCCGCTTACCAAGTCGCTCAAAAGCAGCCGATGAAACTAGCCGCCATGGAAGGTCTTTATGAGGG
TGGCAACGGAGTAGGACTCGTAGGTATCGGCATCTTAAATCCGGCAAAGACGAGTTATCTGGATAACCAGAACGCATTTA
TTTTTGACATTAAGTTCCCAAAACTCCTCTCCTTCTTAGCAGAACGTGACATCAACGCATACGTTCCGGGTATCGTAAAC
TTGATAGAGGGAGGCTATACGACCAATAAGGGAACGGTAGCGCTCTCCGCCAAAGAAAAAATTGAGAAAGGTAAAGCCGC
TATCAAAGCGTTAGCTGATTATCGTAAAGCGGTCAAAGATAAAGATACCGCAGCCGCCGGGCAATACAGGGTAACTTTGG
AAGAAAATTTCCCCTATTTCGGATATGGTTATATTAAGGATCCGGCAGAGTTAATCCCGCATGTAGGATTGACATTCTAT
TCTTTCCGTGTGATGGTGATCCTTGGTTGTTTCTTCATCTTACTATTCATTATTACGTTGATATGGGATAAAAAAGGGAA
AATCGCTAATACACGTTGGTTGCAATACGTGGGCCTATGGTCTATACCTTTAGGATATATAGCGGGACAAGCCGGTTGGA
TCGTAGCGGAGGTAGGACGTCAACCTTGGGCTATACAGGATATCTTGCCGACCAGCGCTTCGATATCCAAGTTAAACCCG
TCCTCGGTACAGACCACTTTCTACCTGTTCCTTATCTTATTTACGATCCTGCTGATCGCAGAGATTGGAATCATGGTTAA
GGCCATCAAGAAAGGGCCGGAAGCTGCCGCCCACTAA

Upstream 100 bases:

>100_bases
CCTAATTATCTCGGGCAATTCGATAGCGATAGTGAGAAGGAGAACCACGTATCGAACGAACTCATACAACGGGCAATAAA
TCCTTAAAACATTAATAAAT

Downstream 100 bases:

>100_bases
TTTTCAATTTTCAAATATCAATTCTTAATTAGAAAGTCCTATGGATAGTACATATATATTGTTACAACATTACTGGTGGT
TTCTGGTATCTCTACTGGGA

Product: cytochrome D ubiquinol oxidase subunit I

Products: ubiquinone-8; H2O [C]

Alternate protein names: Cytochrome bd-II oxidase subunit I [H]

Number of amino acids: Translated: 518; Mature: 518

Protein sequence:

>518_residues
MIENIDTSLIDWSRAQFALTAMYHWLFVPLTLGLGVIQAIMETIYYRTGNEAWKKTAQFWMKLFGINFAIGVATGLILEF
EFGTNWSNYSWFVGDIFGAPLAIEGILAFFMEATFIAVMFFGWDKVSKRFHLASTWLTIIGATLSALWILIANAWMQYPV
GMHFNPDTVRNEMFDFWAVALSPVAINKFFHTVLSGWIVGALFVLGISCWYLLKKRNTEFALSSIKVSAIFGLVASILII
WTGDGSAYQVAQKQPMKLAAMEGLYEGGNGVGLVGIGILNPAKTSYLDNQNAFIFDIKFPKLLSFLAERDINAYVPGIVN
LIEGGYTTNKGTVALSAKEKIEKGKAAIKALADYRKAVKDKDTAAAGQYRVTLEENFPYFGYGYIKDPAELIPHVGLTFY
SFRVMVILGCFFILLFIITLIWDKKGKIANTRWLQYVGLWSIPLGYIAGQAGWIVAEVGRQPWAIQDILPTSASISKLNP
SSVQTTFYLFLILFTILLIAEIGIMVKAIKKGPEAAAH

Sequences:

>Translated_518_residues
MIENIDTSLIDWSRAQFALTAMYHWLFVPLTLGLGVIQAIMETIYYRTGNEAWKKTAQFWMKLFGINFAIGVATGLILEF
EFGTNWSNYSWFVGDIFGAPLAIEGILAFFMEATFIAVMFFGWDKVSKRFHLASTWLTIIGATLSALWILIANAWMQYPV
GMHFNPDTVRNEMFDFWAVALSPVAINKFFHTVLSGWIVGALFVLGISCWYLLKKRNTEFALSSIKVSAIFGLVASILII
WTGDGSAYQVAQKQPMKLAAMEGLYEGGNGVGLVGIGILNPAKTSYLDNQNAFIFDIKFPKLLSFLAERDINAYVPGIVN
LIEGGYTTNKGTVALSAKEKIEKGKAAIKALADYRKAVKDKDTAAAGQYRVTLEENFPYFGYGYIKDPAELIPHVGLTFY
SFRVMVILGCFFILLFIITLIWDKKGKIANTRWLQYVGLWSIPLGYIAGQAGWIVAEVGRQPWAIQDILPTSASISKLNP
SSVQTTFYLFLILFTILLIAEIGIMVKAIKKGPEAAAH
>Mature_518_residues
MIENIDTSLIDWSRAQFALTAMYHWLFVPLTLGLGVIQAIMETIYYRTGNEAWKKTAQFWMKLFGINFAIGVATGLILEF
EFGTNWSNYSWFVGDIFGAPLAIEGILAFFMEATFIAVMFFGWDKVSKRFHLASTWLTIIGATLSALWILIANAWMQYPV
GMHFNPDTVRNEMFDFWAVALSPVAINKFFHTVLSGWIVGALFVLGISCWYLLKKRNTEFALSSIKVSAIFGLVASILII
WTGDGSAYQVAQKQPMKLAAMEGLYEGGNGVGLVGIGILNPAKTSYLDNQNAFIFDIKFPKLLSFLAERDINAYVPGIVN
LIEGGYTTNKGTVALSAKEKIEKGKAAIKALADYRKAVKDKDTAAAGQYRVTLEENFPYFGYGYIKDPAELIPHVGLTFY
SFRVMVILGCFFILLFIITLIWDKKGKIANTRWLQYVGLWSIPLGYIAGQAGWIVAEVGRQPWAIQDILPTSASISKLNP
SSVQTTFYLFLILFTILLIAEIGIMVKAIKKGPEAAAH

Specific function: Cytochrome oxidase subunit [H]

COG id: COG1271

COG function: function code C; Cytochrome bd-type quinol oxidase, subunit 1

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytochrome ubiquinol oxidase subunit 1 family [H]

Homologues:

Organism=Escherichia coli, GI1787212, Length=528, Percent_Identity=43.5606060606061, Blast_Score=413, Evalue=1e-116,
Organism=Escherichia coli, GI87081779, Length=533, Percent_Identity=41.6510318949343, Blast_Score=391, Evalue=1e-110,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002585 [H]

Pfam domain/function: PF01654 Bac_Ubq_Cox [H]

EC number: 1.10.3.- [C]

Molecular weight: Translated: 57681; Mature: 57681

Theoretical pI: Translated: 9.14; Mature: 9.14

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIENIDTSLIDWSRAQFALTAMYHWLFVPLTLGLGVIQAIMETIYYRTGNEAWKKTAQFW
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
MKLFGINFAIGVATGLILEFEFGTNWSNYSWFVGDIFGAPLAIEGILAFFMEATFIAVMF
HHHHCCHHHHHHHHCEEEEEEECCCCCCCCEEEHHHCCCCHHHHHHHHHHHHHHHHHHHH
FGWDKVSKRFHLASTWLTIIGATLSALWILIANAWMQYPVGMHFNPDTVRNEMFDFWAVA
HCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHH
LSPVAINKFFHTVLSGWIVGALFVLGISCWYLLKKRNTEFALSSIKVSAIFGLVASILII
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHEEE
WTGDGSAYQVAQKQPMKLAAMEGLYEGGNGVGLVGIGILNPAKTSYLDNQNAFIFDIKFP
ECCCCCEEEHHHCCCHHHHHHHHHHCCCCEEEEEEEEECCCHHHHHCCCCCCEEEEECHH
KLLSFLAERDINAYVPGIVNLIEGGYTTNKGTVALSAKEKIEKGKAAIKALADYRKAVKD
HHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHCC
KDTAAAGQYRVTLEENFPYFGYGYIKDPAELIPHVGLTFYSFRVMVILGCFFILLFIITL
CCCCCCCEEEEEEECCCCEECCCCCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHH
IWDKKGKIANTRWLQYVGLWSIPLGYIAGQAGWIVAEVGRQPWAIQDILPTSASISKLNP
HHCCCCCCCCHHHHHHHHHHHCCHHHHCCCCCEEEEECCCCCCCHHHHCCCCCCCCCCCC
SSVQTTFYLFLILFTILLIAEIGIMVKAIKKGPEAAAH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MIENIDTSLIDWSRAQFALTAMYHWLFVPLTLGLGVIQAIMETIYYRTGNEAWKKTAQFW
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
MKLFGINFAIGVATGLILEFEFGTNWSNYSWFVGDIFGAPLAIEGILAFFMEATFIAVMF
HHHHCCHHHHHHHHCEEEEEEECCCCCCCCEEEHHHCCCCHHHHHHHHHHHHHHHHHHHH
FGWDKVSKRFHLASTWLTIIGATLSALWILIANAWMQYPVGMHFNPDTVRNEMFDFWAVA
HCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHH
LSPVAINKFFHTVLSGWIVGALFVLGISCWYLLKKRNTEFALSSIKVSAIFGLVASILII
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHEEE
WTGDGSAYQVAQKQPMKLAAMEGLYEGGNGVGLVGIGILNPAKTSYLDNQNAFIFDIKFP
ECCCCCEEEHHHCCCHHHHHHHHHHCCCCEEEEEEEEECCCHHHHHCCCCCCEEEEECHH
KLLSFLAERDINAYVPGIVNLIEGGYTTNKGTVALSAKEKIEKGKAAIKALADYRKAVKD
HHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHCC
KDTAAAGQYRVTLEENFPYFGYGYIKDPAELIPHVGLTFYSFRVMVILGCFFILLFIITL
CCCCCCCEEEEEEECCCCEECCCCCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHH
IWDKKGKIANTRWLQYVGLWSIPLGYIAGQAGWIVAEVGRQPWAIQDILPTSASISKLNP
HHCCCCCCCCHHHHHHHHHHHCCHHHHCCCCCEEEEECCCCCCCHHHHCCCCCCCCCCCC
SSVQTTFYLFLILFTILLIAEIGIMVKAIKKGPEAAAH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Fe [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ubiquinol-8; O2 [C]

Specific reaction: ubiquinol-8 + O2 = ubiquinone-8 + H2O [C]

General reaction: Oxidoreductases; Acting on diphenols and related substances as donors; With oxygen as acceptor [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1658595; 8905232; 9278503; 8626304 [H]