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The map label for this gene is lpxH [H]

Identifier: 150009189

GI number: 150009189

Start: 3067395

End: 3068174

Strand: Direct

Name: lpxH [H]

Synonym: BDI_2591

Alternate gene names: 150009189

Gene position: 3067395-3068174 (Clockwise)

Preceding gene: 150009188

Following gene: 150009192

Centisome position: 63.75

GC content: 46.79

Gene sequence:

>780_bases
ATGAAAATATATTTCGCCTCAGACGCACATCTGGGAGCCCGTTTCCACAAGGACCCTTTAGCCATCGAGAAGAAACTGGT
ACGTTGGCTGGATAGCATCAAGGAAGACGCTTCCGCCATTTGGTTTCTGGGAGATCTATTCGACTATTGGTACGAATACA
AATACGTCGTGCCGAAAGGCCATGTACGTTTTCTGGGGAAATTGGCCGAGTTAGCGGACAGAGGTATAGAAATACATATC
TTTATCGGTAACCATGACATCTGGATGTTCGACTACTTGCCGAAAGAGATAGGCGCCATCATCCATCGGGATACCTTGAC
AGTCGATTTATTAGGGAAACGTTTCTTCCTCGGGCATGGCGATGAGGTAGATTTCCGGAGTAAGGCATTCCGTCTGATCA
GGGCTATTTTCCGGAACAAGTTCTGCCAATGGTTATATGCGGGAATACATCCCCGCTGGACGTTCGGGTTCGCTTTAGGC
TGGTCGCTCAACAGCCGGAAGAGCGGACTGGAAAAGCAAGAGGCTAAAAAGTATCAAGGGGAAGACGCAGAATATATGGT
TGTTTTCGCCAAGGAATATCTAAAGACGCATCCCGATATAAACTTCTTCATTTTCGGCCATCGCCACATCATGTTGGACT
TGATGTTAAGCCGTACCTCCCGTATTCTCATAGCCGGGGATTGGATGCAATTCTTCTCTTATATCGTATGGGATGGCGAG
AATCTGTATATGGATCAGTTTCTGGAAGAGACGGACGGACAATCTTATCCCAACACATAA

Upstream 100 bases:

>100_bases
CGGTCGATGGGGTGAACAATGTAGAGGTAAACCTCGTCTTCGAGCCGGAATGGGACAAGGACATGATGACGGAGGAGGCT
AAACTGGAATTAGGTTTTCT

Downstream 100 bases:

>100_bases
GACAGCGTTGTCTTAACACCTTAGACAGTACTGTCGAAGCACCTTAGACAGCGTTGTATGATGTGCTCATACAACGCTGT
CCGGATTCTCCGCTTACTTT

Product: UDP-2,3-diacylglucosamine hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 259; Mature: 259

Protein sequence:

>259_residues
MKIYFASDAHLGARFHKDPLAIEKKLVRWLDSIKEDASAIWFLGDLFDYWYEYKYVVPKGHVRFLGKLAELADRGIEIHI
FIGNHDIWMFDYLPKEIGAIIHRDTLTVDLLGKRFFLGHGDEVDFRSKAFRLIRAIFRNKFCQWLYAGIHPRWTFGFALG
WSLNSRKSGLEKQEAKKYQGEDAEYMVVFAKEYLKTHPDINFFIFGHRHIMLDLMLSRTSRILIAGDWMQFFSYIVWDGE
NLYMDQFLEETDGQSYPNT

Sequences:

>Translated_259_residues
MKIYFASDAHLGARFHKDPLAIEKKLVRWLDSIKEDASAIWFLGDLFDYWYEYKYVVPKGHVRFLGKLAELADRGIEIHI
FIGNHDIWMFDYLPKEIGAIIHRDTLTVDLLGKRFFLGHGDEVDFRSKAFRLIRAIFRNKFCQWLYAGIHPRWTFGFALG
WSLNSRKSGLEKQEAKKYQGEDAEYMVVFAKEYLKTHPDINFFIFGHRHIMLDLMLSRTSRILIAGDWMQFFSYIVWDGE
NLYMDQFLEETDGQSYPNT
>Mature_259_residues
MKIYFASDAHLGARFHKDPLAIEKKLVRWLDSIKEDASAIWFLGDLFDYWYEYKYVVPKGHVRFLGKLAELADRGIEIHI
FIGNHDIWMFDYLPKEIGAIIHRDTLTVDLLGKRFFLGHGDEVDFRSKAFRLIRAIFRNKFCQWLYAGIHPRWTFGFALG
WSLNSRKSGLEKQEAKKYQGEDAEYMVVFAKEYLKTHPDINFFIFGHRHIMLDLMLSRTSRILIAGDWMQFFSYIVWDGE
NLYMDQFLEETDGQSYPNT

Specific function: Catalyzes the hydrolysis of the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1- phosphate (lipid X) and UMP [H]

COG id: COG2908

COG function: function code S; Uncharacterized protein conserved in bacteria

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the lpxH family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004843
- InterPro:   IPR010138 [H]

Pfam domain/function: PF00149 Metallophos [H]

EC number: 3.6.1.-

Molecular weight: Translated: 30677; Mature: 30677

Theoretical pI: Translated: 7.14; Mature: 7.14

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIYFASDAHLGARFHKDPLAIEKKLVRWLDSIKEDASAIWFLGDLFDYWYEYKYVVPKG
CEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCC
HVRFLGKLAELADRGIEIHIFIGNHDIWMFDYLPKEIGAIIHRDTLTVDLLGKRFFLGHG
HHHHHHHHHHHHHCCEEEEEEECCCCEEEEECCHHHHHHHHHCCCEEEEECCCEEEECCC
DEVDFRSKAFRLIRAIFRNKFCQWLYAGIHPRWTFGFALGWSLNSRKSGLEKQEAKKYQG
CCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCHHCCCCHHHHHHHCC
EDAEYMVVFAKEYLKTHPDINFFIFGHRHIMLDLMLSRTSRILIAGDWMQFFSYIVWDGE
CCCCEEEEEEHHHHHHCCCCEEEEEECHHHHHHHHHHCCCEEEEEECHHHHHHEEEECCC
NLYMDQFLEETDGQSYPNT
CHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MKIYFASDAHLGARFHKDPLAIEKKLVRWLDSIKEDASAIWFLGDLFDYWYEYKYVVPKG
CEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCC
HVRFLGKLAELADRGIEIHIFIGNHDIWMFDYLPKEIGAIIHRDTLTVDLLGKRFFLGHG
HHHHHHHHHHHHHCCEEEEEEECCCCEEEEECCHHHHHHHHHCCCEEEEECCCEEEECCC
DEVDFRSKAFRLIRAIFRNKFCQWLYAGIHPRWTFGFALGWSLNSRKSGLEKQEAKKYQG
CCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCHHCCCCHHHHHHHCC
EDAEYMVVFAKEYLKTHPDINFFIFGHRHIMLDLMLSRTSRILIAGDWMQFFSYIVWDGE
CCCCEEEEEEHHHHHHCCCCEEEEEECHHHHHHHHHHCCCEEEEEECHHHHHHEEEECCC
NLYMDQFLEETDGQSYPNT
CHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA