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The map label for this gene is tadA [H]

Identifier: 150009165

GI number: 150009165

Start: 3039101

End: 3039541

Strand: Direct

Name: tadA [H]

Synonym: BDI_2567

Alternate gene names: 150009165

Gene position: 3039101-3039541 (Clockwise)

Preceding gene: 150009164

Following gene: 150009171

Centisome position: 63.16

GC content: 49.66

Gene sequence:

>441_bases
ATGAATCCTTTCAATGACGAATATTTCATGAAGCAAGCGTTGGTGGAAGCTCGTGCGGCAGCGTCCGAGGGTGAGGTTCC
CGTAGGAGCTGTTATCGTCTGCAACAACCAGATCATAGCGAGGGCGCATAATCAAACCGAATGCTTGAACGACGTGACCG
CACATGCCGAGATGTTGGCGATTACGGCCGCCGCCGGAGTCTTAGGAGCGAAATACCTGACAAATTGTAGTCTATACGTA
ACCGTGGAACCCTGCATAATGTGTGCCGGCGCGATCGGATGGGCACAATTAAGCACGATCGTATACGGGGCATCCGATGA
TAAAAGAGGTTTCTCCAAATTCGCCCCTCAAGCCTTCCATCCGAAAGCGATTATCAAAAAAGGTATCCTTGAAAAAGAGT
GCGCGGAAGAAATGCAGCGTTTCTTTAAGCAAAGACGCTAA

Upstream 100 bases:

>100_bases
AGAATAAGTCCCGTTGGTACCGAGAGACGATCCTTTCTCACATCCTCAAGACCTTGGAGGAGGATTATCCGACTCTTTTC
AACGAAAATGAGATGAGAAG

Downstream 100 bases:

>100_bases
GCTCTATTTAACTTCCTCGTAATCCACATACTCCCCTTCATCCTTGGCGAATATCTTCTTACGGTGCACATAAGGTGTAC
GATCATCATCATCGTCCCGG

Product: putative cytosine/adenosine deaminase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 146; Mature: 146

Protein sequence:

>146_residues
MNPFNDEYFMKQALVEARAAASEGEVPVGAVIVCNNQIIARAHNQTECLNDVTAHAEMLAITAAAGVLGAKYLTNCSLYV
TVEPCIMCAGAIGWAQLSTIVYGASDDKRGFSKFAPQAFHPKAIIKKGILEKECAEEMQRFFKQRR

Sequences:

>Translated_146_residues
MNPFNDEYFMKQALVEARAAASEGEVPVGAVIVCNNQIIARAHNQTECLNDVTAHAEMLAITAAAGVLGAKYLTNCSLYV
TVEPCIMCAGAIGWAQLSTIVYGASDDKRGFSKFAPQAFHPKAIIKKGILEKECAEEMQRFFKQRR
>Mature_146_residues
MNPFNDEYFMKQALVEARAAASEGEVPVGAVIVCNNQIIARAHNQTECLNDVTAHAEMLAITAAAGVLGAKYLTNCSLYV
TVEPCIMCAGAIGWAQLSTIVYGASDDKRGFSKFAPQAFHPKAIIKKGILEKECAEEMQRFFKQRR

Specific function: Deaminates adenosine-34 to inosine in tRNA-Arg2 [H]

COG id: COG0590

COG function: function code FJ; Cytosine/adenosine deaminases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytidine and deoxycytidylate deaminase family [H]

Homologues:

Organism=Homo sapiens, GI124107608, Length=152, Percent_Identity=32.2368421052632, Blast_Score=79, Evalue=2e-15,
Organism=Escherichia coli, GI145693172, Length=148, Percent_Identity=40.5405405405405, Blast_Score=115, Evalue=2e-27,
Organism=Caenorhabditis elegans, GI17554608, Length=139, Percent_Identity=33.0935251798561, Blast_Score=78, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17541138, Length=108, Percent_Identity=38.8888888888889, Blast_Score=75, Evalue=9e-15,
Organism=Caenorhabditis elegans, GI17555996, Length=122, Percent_Identity=36.8852459016393, Blast_Score=71, Evalue=2e-13,
Organism=Drosophila melanogaster, GI21355527, Length=108, Percent_Identity=40.7407407407407, Blast_Score=78, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR016193 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1 [H]

EC number: NA

Molecular weight: Translated: 15945; Mature: 15945

Theoretical pI: Translated: 7.30; Mature: 7.30

Prosite motif: PS00903 CYT_DCMP_DEAMINASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.1 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
7.5 %Cys+Met (Translated Protein)
4.1 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
7.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNPFNDEYFMKQALVEARAAASEGEVPVGAVIVCNNQIIARAHNQTECLNDVTAHAEMLA
CCCCCHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCEEEEECCCHHHHHHHHHHHHHHHH
ITAAAGVLGAKYLTNCSLYVTVEPCIMCAGAIGWAQLSTIVYGASDDKRGFSKFAPQAFH
HHHHHHHHHHHHHHCCEEEEEECHHHHHHCCCCHHHHHHHEECCCCCCCCHHHCCCCCCC
PKAIIKKGILEKECAEEMQRFFKQRR
CHHHHHHCCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNPFNDEYFMKQALVEARAAASEGEVPVGAVIVCNNQIIARAHNQTECLNDVTAHAEMLA
CCCCCHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCEEEEECCCHHHHHHHHHHHHHHHH
ITAAAGVLGAKYLTNCSLYVTVEPCIMCAGAIGWAQLSTIVYGASDDKRGFSKFAPQAFH
HHHHHHHHHHHHHHCCEEEEEECHHHHHHCCCCHHHHHHHEECCCCCCCCHHHCCCCCCC
PKAIIKKGILEKECAEEMQRFFKQRR
CHHHHHHCCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1698458; 7584024; 9384377 [H]