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The map label for this gene is fabH

Identifier: 150009040

GI number: 150009040

Start: 2865581

End: 2866585

Strand: Reverse

Name: fabH

Synonym: BDI_2436

Alternate gene names: 150009040

Gene position: 2866585-2865581 (Counterclockwise)

Preceding gene: 150009041

Following gene: 150009039

Centisome position: 59.58

GC content: 47.96

Gene sequence:

>1005_bases
ATGGATAAGATAAATGCGGTTATCACAGGAGTGGGTGGATACGTTCCTGAAGATGTATTGACGAATGAGGATATTTCCAA
GATGGTCGATACGACGGATGAGTGGATCATGACTCGTGTGGGTATTAAGGAGCGCAGGATATTGAAAGGGGAGGGCGTAG
GACTCTCTTACATGGGTATACGGGCCGTGAAGCAATTGCTCGAGAAAACGAACCTGAATCCGGAAGAAGTAGAGGTTGTC
TTGACCGCTACGACTACCCCGGATCATCATTTCCCGACAACTTCTTCTATCATCGCTTATCATACAGGTTGTAAGAATGC
GATGACTTTTGATATGCAAGGTGCGTGCGCAGGCTTCTTGTATGCTTTGGAGACGGGCGCTAATTATATTCGCTCGGGGC
GTTATAAGAAGGTGGTTGTCGTATCGGGTGATAAGATGACATCTATTACAGATTATCAAGATCGTTCTACTTGTCCTTTG
TTCGGGGATGCTTGCGGAGCGGTCTTGCTGGAGCCAACTACCGAGGAGTTCGGTGTCTTGGATACTATTTTACGGACAGA
CGGCGTAGGCTATCCGCATCTGATCATGAAATCGGGCGGCTCGGCTTATCCTCCTTCTCACGAGACGGTGGATAACCGTG
AGCATTTCGTTTATCAAGATGGACGTGTGGTGTTCAAGTACGCGGTTTCTTATATGGCGGACGTGGCCGCTGAGATTGCG
GAGAAGAATGGCTTGACGCATGATGATATCGCGTGGATCGTTCCTCATCAAGCGAACTTGCGGATTATCGACGCTACGGC
GAAACGCTTGGGCGTAGATATGGATAAGGTGATGATCAATATCCAGAAATACGGCAACACAAGCGCCGGTACGATTCCTA
TTTGTCTATGGGAATGGGAGAATCAATTGAAAAAAGGAGATAACCTGATCCTCGCCGCTTTTGGAGCGGGCTTTACGTGG
GGAGCGGTTTATCTGAAATGGGGGTATGATGGAAAAAAAGCATAA

Upstream 100 bases:

>100_bases
TTGTCAACTTATATGGTTTGATGAACAAAAGAAATAGCCCTAAAAGTTTTTTTAGGGCTTTTTTTTAATTGGGATAAGTA
GTCCTTTTATTTTTAAAGTT

Downstream 100 bases:

>100_bases
ATCGGGTTTTGTCAATATCGTTGGAAACCCAAACGTAGGTAAGTCTACGTTGATGAATCGTTTGGTCGGGGAGCGGATCT
CTATTATCACCTCGAAGGCG

Product: 3-oxoacyl-[acyl-carrier-protein] synthase III

Products: NA

Alternate protein names: 3-oxoacyl-[acyl-carrier-protein] synthase III; Beta-ketoacyl-ACP synthase III; KAS III

Number of amino acids: Translated: 334; Mature: 334

Protein sequence:

>334_residues
MDKINAVITGVGGYVPEDVLTNEDISKMVDTTDEWIMTRVGIKERRILKGEGVGLSYMGIRAVKQLLEKTNLNPEEVEVV
LTATTTPDHHFPTTSSIIAYHTGCKNAMTFDMQGACAGFLYALETGANYIRSGRYKKVVVVSGDKMTSITDYQDRSTCPL
FGDACGAVLLEPTTEEFGVLDTILRTDGVGYPHLIMKSGGSAYPPSHETVDNREHFVYQDGRVVFKYAVSYMADVAAEIA
EKNGLTHDDIAWIVPHQANLRIIDATAKRLGVDMDKVMINIQKYGNTSAGTIPICLWEWENQLKKGDNLILAAFGAGFTW
GAVYLKWGYDGKKA

Sequences:

>Translated_334_residues
MDKINAVITGVGGYVPEDVLTNEDISKMVDTTDEWIMTRVGIKERRILKGEGVGLSYMGIRAVKQLLEKTNLNPEEVEVV
LTATTTPDHHFPTTSSIIAYHTGCKNAMTFDMQGACAGFLYALETGANYIRSGRYKKVVVVSGDKMTSITDYQDRSTCPL
FGDACGAVLLEPTTEEFGVLDTILRTDGVGYPHLIMKSGGSAYPPSHETVDNREHFVYQDGRVVFKYAVSYMADVAAEIA
EKNGLTHDDIAWIVPHQANLRIIDATAKRLGVDMDKVMINIQKYGNTSAGTIPICLWEWENQLKKGDNLILAAFGAGFTW
GAVYLKWGYDGKKA
>Mature_334_residues
MDKINAVITGVGGYVPEDVLTNEDISKMVDTTDEWIMTRVGIKERRILKGEGVGLSYMGIRAVKQLLEKTNLNPEEVEVV
LTATTTPDHHFPTTSSIIAYHTGCKNAMTFDMQGACAGFLYALETGANYIRSGRYKKVVVVSGDKMTSITDYQDRSTCPL
FGDACGAVLLEPTTEEFGVLDTILRTDGVGYPHLIMKSGGSAYPPSHETVDNREHFVYQDGRVVFKYAVSYMADVAAEIA
EKNGLTHDDIAWIVPHQANLRIIDATAKRLGVDMDKVMINIQKYGNTSAGTIPICLWEWENQLKKGDNLILAAFGAGFTW
GAVYLKWGYDGKKA

Specific function: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the

COG id: COG0332

COG function: function code I; 3-oxoacyl-[acyl-carrier-protein] synthase III

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fabH family

Homologues:

Organism=Escherichia coli, GI1787333, Length=322, Percent_Identity=39.7515527950311, Blast_Score=236, Evalue=2e-63,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): FABH_PARD8 (A6LEP7)

Other databases:

- EMBL:   CP000140
- RefSeq:   YP_001303783.1
- ProteinModelPortal:   A6LEP7
- SMR:   A6LEP7
- STRING:   A6LEP7
- GeneID:   5307585
- GenomeReviews:   CP000140_GR
- KEGG:   pdi:BDI_2436
- eggNOG:   COG0332
- HOGENOM:   HBG649927
- BioCyc:   PDIS435591:BDI_2436-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_01815
- InterPro:   IPR013751
- InterPro:   IPR013747
- InterPro:   IPR004655
- InterPro:   IPR016039
- InterPro:   IPR016038
- Gene3D:   G3DSA:3.40.47.10
- TIGRFAMs:   TIGR00747

Pfam domain/function: PF08545 ACP_syn_III; PF08541 ACP_syn_III_C; SSF53901 Thiolase-like

EC number: =2.3.1.41

Molecular weight: Translated: 36767; Mature: 36767

Theoretical pI: Translated: 5.41; Mature: 5.41

Prosite motif: NA

Important sites: ACT_SITE 116-116 ACT_SITE 256-256 ACT_SITE 286-286

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDKINAVITGVGGYVPEDVLTNEDISKMVDTTDEWIMTRVGIKERRILKGEGVGLSYMGI
CCCCEEEEEECCCCCCCHHCCCHHHHHHHCCHHHHHHHHCCCCHHEEEECCCCCEEHHHH
RAVKQLLEKTNLNPEEVEVVLTATTTPDHHFPTTSSIIAYHTGCKNAMTFDMQGACAGFL
HHHHHHHHHHCCCHHHEEEEEEEECCCCCCCCCCCCEEEEECCCCCCEEEECCCHHHHHH
YALETGANYIRSGRYKKVVVVSGDKMTSITDYQDRSTCPLFGDACGAVLLEPTTEEFGVL
HHHHHCHHHHHCCCCEEEEEEECCCEEEECCCCCCCCCCCCCCCCCEEEECCCCHHHHHH
DTILRTDGVGYPHLIMKSGGSAYPPSHETVDNREHFVYQDGRVVFKYAVSYMADVAAEIA
HHHHHHCCCCCCEEEEECCCCCCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHH
EKNGLTHDDIAWIVPHQANLRIIDATAKRLGVDMDKVMINIQKYGNTSAGTIPICLWEWE
HHCCCCCCCEEEEECCCCCEEEEECCHHHHCCCHHHHEEEEECCCCCCCCEEEEEEEECH
NQLKKGDNLILAAFGAGFTWGAVYLKWGYDGKKA
HHHCCCCCEEEEEECCCCEEEEEEEEECCCCCCC
>Mature Secondary Structure
MDKINAVITGVGGYVPEDVLTNEDISKMVDTTDEWIMTRVGIKERRILKGEGVGLSYMGI
CCCCEEEEEECCCCCCCHHCCCHHHHHHHCCHHHHHHHHCCCCHHEEEECCCCCEEHHHH
RAVKQLLEKTNLNPEEVEVVLTATTTPDHHFPTTSSIIAYHTGCKNAMTFDMQGACAGFL
HHHHHHHHHHCCCHHHEEEEEEEECCCCCCCCCCCCEEEEECCCCCCEEEECCCHHHHHH
YALETGANYIRSGRYKKVVVVSGDKMTSITDYQDRSTCPLFGDACGAVLLEPTTEEFGVL
HHHHHCHHHHHCCCCEEEEEEECCCEEEECCCCCCCCCCCCCCCCCEEEECCCCHHHHHH
DTILRTDGVGYPHLIMKSGGSAYPPSHETVDNREHFVYQDGRVVFKYAVSYMADVAAEIA
HHHHHHCCCCCCEEEEECCCCCCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHH
EKNGLTHDDIAWIVPHQANLRIIDATAKRLGVDMDKVMINIQKYGNTSAGTIPICLWEWE
HHCCCCCCCEEEEECCCCCEEEEECCHHHHCCCHHHHEEEEECCCCCCCCEEEEEEEECH
NQLKKGDNLILAAFGAGFTWGAVYLKWGYDGKKA
HHHCCCCCEEEEEECCCCEEEEEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA