Click here to switch to the map view.

The map label for this gene is era [H]

Identifier: 150009039

GI number: 150009039

Start: 2864707

End: 2865597

Strand: Reverse

Name: era [H]

Synonym: BDI_2435

Alternate gene names: 150009039

Gene position: 2865597-2864707 (Counterclockwise)

Preceding gene: 150009040

Following gene: 150009038

Centisome position: 59.56

GC content: 46.8

Gene sequence:

>891_bases
ATGGAAAAAAAGCATAAATCGGGTTTTGTCAATATCGTTGGAAACCCAAACGTAGGTAAGTCTACGTTGATGAATCGTTT
GGTCGGGGAGCGGATCTCTATTATCACCTCGAAGGCGCAAACGACAAGGCATCGTATTATGGGTATCGTGAATACCGACG
ATATGCAAATCGTGTATTCTGACACGCCGGGAGTCTTGCGGCCGAATTATAAGTTGCAGGAATCCATGCTTAATTTCTCT
CAATCCGCCTTAGGCGACGCCGACGTGCTGTTGTACGTGACGGATGTCGTCGAGACGATTGATAAAAATAATGAGTTCCT
AGCACGGGTACAGAGTATAGAGTGTCCGGTTCTCTTGTTGATCAATAAGATCGACCAGACCAATCAGCCGGAGCTGGAGA
AGCTCGTGGCCCAGTGGAAGGAATTGCTTCCGAAGGCCGAGATCATCCCGATCTCCGCGCTTTCGAATTTCAATATAGAT
TACGTGAAGCGTCGGGTGGAGGAGTTGATGCCTGATTCCCCGCCTTATTTCGAGAAAGACGCCTTGACCGATAAACCGGC
CCGTTTCTTCGTGACAGAGATCATTCGTGAGAAAATCTTGTTATATTATCAGAAGGAAATACCTTATGCGGTAGAAGTGG
TCGTCGAGTTGTTCAAGGAAGATGATGAGCTGATCCATATCAAGGCGCTGATCATCGTGGAGCGTGATACCCAGAAGGGG
ATCATCATCGGGCATCAAGGGCAAGCATTGAAGAAAGTAGGTGCTATGGCCCGGAAGGATATCGAACGTTTCTTCGGAAA
GAAGGTGTTTTTGGAAATGTTTGTCAAAGTGGAAAAAGACTGGCGTAACCGTGACAACATATTGAAGAACTTCGGTTATC
AGCTGGACTAA

Upstream 100 bases:

>100_bases
TGGGAATGGGAGAATCAATTGAAAAAAGGAGATAACCTGATCCTCGCCGCTTTTGGAGCGGGCTTTACGTGGGGAGCGGT
TTATCTGAAATGGGGGTATG

Downstream 100 bases:

>100_bases
TAATAGCATACGAAAGGAGAATTTATGGGAAATATAGTAGCGATAGTGGGGAGACCCAATGTAGGTAAGTCAACCCTTTT
CAACCGGTTGACGGGTACCC

Product: GTP-binding protein Era

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 296; Mature: 296

Protein sequence:

>296_residues
MEKKHKSGFVNIVGNPNVGKSTLMNRLVGERISIITSKAQTTRHRIMGIVNTDDMQIVYSDTPGVLRPNYKLQESMLNFS
QSALGDADVLLYVTDVVETIDKNNEFLARVQSIECPVLLLINKIDQTNQPELEKLVAQWKELLPKAEIIPISALSNFNID
YVKRRVEELMPDSPPYFEKDALTDKPARFFVTEIIREKILLYYQKEIPYAVEVVVELFKEDDELIHIKALIIVERDTQKG
IIIGHQGQALKKVGAMARKDIERFFGKKVFLEMFVKVEKDWRNRDNILKNFGYQLD

Sequences:

>Translated_296_residues
MEKKHKSGFVNIVGNPNVGKSTLMNRLVGERISIITSKAQTTRHRIMGIVNTDDMQIVYSDTPGVLRPNYKLQESMLNFS
QSALGDADVLLYVTDVVETIDKNNEFLARVQSIECPVLLLINKIDQTNQPELEKLVAQWKELLPKAEIIPISALSNFNID
YVKRRVEELMPDSPPYFEKDALTDKPARFFVTEIIREKILLYYQKEIPYAVEVVVELFKEDDELIHIKALIIVERDTQKG
IIIGHQGQALKKVGAMARKDIERFFGKKVFLEMFVKVEKDWRNRDNILKNFGYQLD
>Mature_296_residues
MEKKHKSGFVNIVGNPNVGKSTLMNRLVGERISIITSKAQTTRHRIMGIVNTDDMQIVYSDTPGVLRPNYKLQESMLNFS
QSALGDADVLLYVTDVVETIDKNNEFLARVQSIECPVLLLINKIDQTNQPELEKLVAQWKELLPKAEIIPISALSNFNID
YVKRRVEELMPDSPPYFEKDALTDKPARFFVTEIIREKILLYYQKEIPYAVEVVVELFKEDDELIHIKALIIVERDTQKG
IIIGHQGQALKKVGAMARKDIERFFGKKVFLEMFVKVEKDWRNRDNILKNFGYQLD

Specific function: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism [H]

COG id: COG1159

COG function: function code R; GTPase

Gene ontology:

Cell location: Cytoplasm. Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 KH type-2 domain [H]

Homologues:

Organism=Homo sapiens, GI24307899, Length=326, Percent_Identity=24.2331288343558, Blast_Score=80, Evalue=3e-15,
Organism=Escherichia coli, GI1788919, Length=297, Percent_Identity=37.037037037037, Blast_Score=209, Evalue=2e-55,
Organism=Escherichia coli, GI87082120, Length=145, Percent_Identity=31.7241379310345, Blast_Score=62, Evalue=6e-11,
Organism=Drosophila melanogaster, GI24646434, Length=306, Percent_Identity=22.2222222222222, Blast_Score=77, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005662
- InterPro:   IPR006073
- InterPro:   IPR015946
- InterPro:   IPR009019
- InterPro:   IPR004044
- InterPro:   IPR002917
- InterPro:   IPR005225 [H]

Pfam domain/function: PF07650 KH_2; PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 34129; Mature: 34129

Theoretical pI: Translated: 6.97; Mature: 6.97

Prosite motif: PS50823 KH_TYPE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEKKHKSGFVNIVGNPNVGKSTLMNRLVGERISIITSKAQTTRHRIMGIVNTDDMQIVYS
CCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCEEEEEC
DTPGVLRPNYKLQESMLNFSQSALGDADVLLYVTDVVETIDKNNEFLARVQSIECPVLLL
CCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCEEE
INKIDQTNQPELEKLVAQWKELLPKAEIIPISALSNFNIDYVKRRVEELMPDSPPYFEKD
EHHCCCCCCHHHHHHHHHHHHHCCCCCEEEEHHHCCCCHHHHHHHHHHHCCCCCCCCCCC
ALTDKPARFFVTEIIREKILLYYQKEIPYAVEVVVELFKEDDELIHIKALIIVERDTQKG
CCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCEEEEEEEEEEEECCCCC
IIIGHQGQALKKVGAMARKDIERFFGKKVFLEMFVKVEKDWRNRDNILKNFGYQLD
EEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCC
>Mature Secondary Structure
MEKKHKSGFVNIVGNPNVGKSTLMNRLVGERISIITSKAQTTRHRIMGIVNTDDMQIVYS
CCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCEEEEEC
DTPGVLRPNYKLQESMLNFSQSALGDADVLLYVTDVVETIDKNNEFLARVQSIECPVLLL
CCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCEEE
INKIDQTNQPELEKLVAQWKELLPKAEIIPISALSNFNIDYVKRRVEELMPDSPPYFEKD
EHHCCCCCCHHHHHHHHHHHHHCCCCCEEEEHHHCCCCHHHHHHHHHHHCCCCCCCCCCC
ALTDKPARFFVTEIIREKILLYYQKEIPYAVEVVVELFKEDDELIHIKALIIVERDTQKG
CCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCEEEEEEEEEEEECCCCC
IIIGHQGQALKKVGAMARKDIERFFGKKVFLEMFVKVEKDWRNRDNILKNFGYQLD
EEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA