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The map label for this gene is surA [H]

Identifier: 150008996

GI number: 150008996

Start: 2801912

End: 2803480

Strand: Reverse

Name: surA [H]

Synonym: BDI_2392

Alternate gene names: 150008996

Gene position: 2803480-2801912 (Counterclockwise)

Preceding gene: 150008997

Following gene: 150008995

Centisome position: 58.27

GC content: 45.83

Gene sequence:

>1569_bases
ATGAAAAAGTTACTTATTTCATTAGGGGTATTCGCTTGTGTGACAGTTAACGCTCAAACCGCATCCGATTCGGTCGTTAT
GACGGTCGCTGGAAAACAAGTGCCTTTATCTGAATTTATTTTTATCGCGGAGAAGAATGGAGAGGTGGATTTATCGAATA
CAAAGTCCGTCAAAAACTATGTCGAGCTATTTAAAAATTTTAAGCTAAAAGTAGCGGAGGCGGAATCTTTAGGGATCGAC
CAGACATCCTCATTCAAAAGTGAGCTGGATGGATACCGGGCTCAGTTGATCGATAGCTATATGTCGGATAAGGAGGGTGA
GAAAGCGGCTGCCCGTGCGGTATATGACCGTGGGGATCACTCGGTAGAGTTGACCCACATCTTATTCCGTTTGCCGGAGA
AGACGGTCTCCAAAGATACGGTAGCTGTATATCAAGAAGCCATGCGAGTATACGAACGTCTCCAGAAAGGAGAGGATATG
GAAACAGTCGGAAAAGCTTTGGCCGAGAAGGATAAGGAGCATGTCGCTTGCGAATATGTACGTTGCTTGCTCCCGATGCA
ATCCCTAAAAGTGTTTGAGGATGCCGCCTATTCCTTGCCGATTGGCGTGGTGTCTGAACCGGTTCGCACGAAATTAGGAT
TTCATTTGATAAAAGTCCATAGTCGTAAACCCAATCCGGGGCGGATACATGTCGCTCATATCTTGATCGCCTTCCCGAAA
GATTCCGCTATTCAGGACTCATCGGCTTTTCTGGCAAAAGCGCAAGCTATCTATAAGCAAGTACAAGAGGGAGCTGATTT
TGGCGAGTTAGCGAAAGAATATTCTGGGGATGCTGCTTCCGCTAAGAAAGAGGGAGTATTACCTTGGTTTGGGGTAGGCG
AGATGGTCCAGCCTTTTGAGCAAGCCGCTTTTGCGTTGAGCAAGCCGGGTGATTTATCCGAGGTGGTGGAAACTCGTTTT
GGTTACCATATCATTAAGTTGATCGATAAGAAGGGACGCCCTTCGTTTGAGGAAGAGGAAAAAGCTTTGTCGAGACGTAT
GGGGCAGGGTGAACGTAACTTCGAGTTATATAAAGCTTTCGACGATCGTATGAAAAAAGAATACGGATACGTTTTCTATC
CGGAAGCCTATGCGGAGCTGCAAGCGTTATGTAATGATTGTTTCCCCACGGACGAGGCGTTTTATGAGAAAGCGAAGGAT
ATGAACAAGACGCTTATGCAATTGGATGGAAAGGATTTCCCGCAAGCGGAGTTCGCTTATTATATCCAACGTTGTCCGTT
CTCGACAAAAACGTATGCGGGTGATTTTATGCAAGAGATCTATGATTTGTTTATCCGCGATATCGTAACGACCGCCGAGC
GTAAGAATCTGGAGACAAAACATCCGGAGATCCCTCATTTGATGCAGGAGTACCGGGATGGGATTCTGTTGTTTGAGGTC
AGCAACCGGGAGATCTGGAGCAAACCCTCCGCCCAGCAGAAGGTGTTGGAAGCGAAGTGGATTGCGGATTTGAATAAAAA
ATATCCGGTGACTGTCAACTGGAAATTATTGAAGAAACTAAAGAAATAA

Upstream 100 bases:

>100_bases
AACACTAATTTAATGGGATAGCATACTTTTCTTGTCGGCTCTCCGTTAGATTAGTGTTATTTTTGTAATGTATATTCGTG
CTATGGTAAAAGAATTTTTG

Downstream 100 bases:

>100_bases
AATAAAGATAGATATGAGGATAGTCTTCATGTTCCTAACGTTCGTTGTGTTGTTGGGTGCCTGTAAAGGTTCTCAGCCAG
CTGATACTACGGATGTCTTG

Product: parvulin-like peptidyl-prolyl isomerase

Products: NA

Alternate protein names: Peptidyl-prolyl cis-trans isomerase surA; PPIase surA; Rotamase surA [H]

Number of amino acids: Translated: 522; Mature: 522

Protein sequence:

>522_residues
MKKLLISLGVFACVTVNAQTASDSVVMTVAGKQVPLSEFIFIAEKNGEVDLSNTKSVKNYVELFKNFKLKVAEAESLGID
QTSSFKSELDGYRAQLIDSYMSDKEGEKAAARAVYDRGDHSVELTHILFRLPEKTVSKDTVAVYQEAMRVYERLQKGEDM
ETVGKALAEKDKEHVACEYVRCLLPMQSLKVFEDAAYSLPIGVVSEPVRTKLGFHLIKVHSRKPNPGRIHVAHILIAFPK
DSAIQDSSAFLAKAQAIYKQVQEGADFGELAKEYSGDAASAKKEGVLPWFGVGEMVQPFEQAAFALSKPGDLSEVVETRF
GYHIIKLIDKKGRPSFEEEEKALSRRMGQGERNFELYKAFDDRMKKEYGYVFYPEAYAELQALCNDCFPTDEAFYEKAKD
MNKTLMQLDGKDFPQAEFAYYIQRCPFSTKTYAGDFMQEIYDLFIRDIVTTAERKNLETKHPEIPHLMQEYRDGILLFEV
SNREIWSKPSAQQKVLEAKWIADLNKKYPVTVNWKLLKKLKK

Sequences:

>Translated_522_residues
MKKLLISLGVFACVTVNAQTASDSVVMTVAGKQVPLSEFIFIAEKNGEVDLSNTKSVKNYVELFKNFKLKVAEAESLGID
QTSSFKSELDGYRAQLIDSYMSDKEGEKAAARAVYDRGDHSVELTHILFRLPEKTVSKDTVAVYQEAMRVYERLQKGEDM
ETVGKALAEKDKEHVACEYVRCLLPMQSLKVFEDAAYSLPIGVVSEPVRTKLGFHLIKVHSRKPNPGRIHVAHILIAFPK
DSAIQDSSAFLAKAQAIYKQVQEGADFGELAKEYSGDAASAKKEGVLPWFGVGEMVQPFEQAAFALSKPGDLSEVVETRF
GYHIIKLIDKKGRPSFEEEEKALSRRMGQGERNFELYKAFDDRMKKEYGYVFYPEAYAELQALCNDCFPTDEAFYEKAKD
MNKTLMQLDGKDFPQAEFAYYIQRCPFSTKTYAGDFMQEIYDLFIRDIVTTAERKNLETKHPEIPHLMQEYRDGILLFEV
SNREIWSKPSAQQKVLEAKWIADLNKKYPVTVNWKLLKKLKK
>Mature_522_residues
MKKLLISLGVFACVTVNAQTASDSVVMTVAGKQVPLSEFIFIAEKNGEVDLSNTKSVKNYVELFKNFKLKVAEAESLGID
QTSSFKSELDGYRAQLIDSYMSDKEGEKAAARAVYDRGDHSVELTHILFRLPEKTVSKDTVAVYQEAMRVYERLQKGEDM
ETVGKALAEKDKEHVACEYVRCLLPMQSLKVFEDAAYSLPIGVVSEPVRTKLGFHLIKVHSRKPNPGRIHVAHILIAFPK
DSAIQDSSAFLAKAQAIYKQVQEGADFGELAKEYSGDAASAKKEGVLPWFGVGEMVQPFEQAAFALSKPGDLSEVVETRF
GYHIIKLIDKKGRPSFEEEEKALSRRMGQGERNFELYKAFDDRMKKEYGYVFYPEAYAELQALCNDCFPTDEAFYEKAKD
MNKTLMQLDGKDFPQAEFAYYIQRCPFSTKTYAGDFMQEIYDLFIRDIVTTAERKNLETKHPEIPHLMQEYRDGILLFEV
SNREIWSKPSAQQKVLEAKWIADLNKKYPVTVNWKLLKKLKK

Specific function: Chaperone involved in the correct folding and assembly of outer membrane proteins. It recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act

COG id: COG0760

COG function: function code O; Parvulin-like peptidyl-prolyl isomerase

Gene ontology:

Cell location: Periplasm. Note=Is capable of associating with the outer membrane (By similarity) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 PpiC domains [H]

Homologues:

Organism=Escherichia coli, GI1786238, Length=247, Percent_Identity=27.5303643724696, Blast_Score=77, Evalue=3e-15,

Paralogues:

None

Copy number: 400 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 160 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000297
- InterPro:   IPR023058
- InterPro:   IPR023034
- InterPro:   IPR015391
- InterPro:   IPR008880 [H]

Pfam domain/function: PF00639 Rotamase; PF09312 SurA_N [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 59336; Mature: 59336

Theoretical pI: Translated: 6.69; Mature: 6.69

Prosite motif: PS50198 PPIC_PPIASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKLLISLGVFACVTVNAQTASDSVVMTVAGKQVPLSEFIFIAEKNGEVDLSNTKSVKNY
CCHHHHHHHHHHHEEECCCCCCCCEEEEECCCCCCHHHEEEEEECCCCEECCCHHHHHHH
VELFKNFKLKVAEAESLGIDQTSSFKSELDGYRAQLIDSYMSDKEGEKAAARAVYDRGDH
HHHHHCCCEEEECHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCC
SVELTHILFRLPEKTVSKDTVAVYQEAMRVYERLQKGEDMETVGKALAEKDKEHVACEYV
CCHHHHHHHHCCHHHHCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCHHHHHHHHH
RCLLPMQSLKVFEDAAYSLPIGVVSEPVRTKLGFHLIKVHSRKPNPGRIHVAHILIAFPK
HHHHCHHHHHHHHHHHHHCCCHHHCCHHHHHHCEEEEEEECCCCCCCEEEEEEEEEECCC
DSAIQDSSAFLAKAQAIYKQVQEGADFGELAKEYSGDAASAKKEGVLPWFGVGEMVQPFE
CCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCHHCHHHCCCCCCCCCHHHHHHHH
QAAFALSKPGDLSEVVETRFGYHIIKLIDKKGRPSFEEEEKALSRRMGQGERNFELYKAF
HHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCCHHHHHHH
DDRMKKEYGYVFYPEAYAELQALCNDCFPTDEAFYEKAKDMNKTLMQLDGKDFPQAEFAY
HHHHHHHCCEEECCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHH
YIQRCPFSTKTYAGDFMQEIYDLFIRDIVTTAERKNLETKHPEIPHLMQEYRDGILLFEV
HHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHCCCEEEEEE
SNREIWSKPSAQQKVLEAKWIADLNKKYPVTVNWKLLKKLKK
CCCHHCCCCCHHHHHHHHHHHHHCCCCCCEEECHHHHHHHCC
>Mature Secondary Structure
MKKLLISLGVFACVTVNAQTASDSVVMTVAGKQVPLSEFIFIAEKNGEVDLSNTKSVKNY
CCHHHHHHHHHHHEEECCCCCCCCEEEEECCCCCCHHHEEEEEECCCCEECCCHHHHHHH
VELFKNFKLKVAEAESLGIDQTSSFKSELDGYRAQLIDSYMSDKEGEKAAARAVYDRGDH
HHHHHCCCEEEECHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCC
SVELTHILFRLPEKTVSKDTVAVYQEAMRVYERLQKGEDMETVGKALAEKDKEHVACEYV
CCHHHHHHHHCCHHHHCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCHHHHHHHHH
RCLLPMQSLKVFEDAAYSLPIGVVSEPVRTKLGFHLIKVHSRKPNPGRIHVAHILIAFPK
HHHHCHHHHHHHHHHHHHCCCHHHCCHHHHHHCEEEEEEECCCCCCCEEEEEEEEEECCC
DSAIQDSSAFLAKAQAIYKQVQEGADFGELAKEYSGDAASAKKEGVLPWFGVGEMVQPFE
CCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCHHCHHHCCCCCCCCCHHHHHHHH
QAAFALSKPGDLSEVVETRFGYHIIKLIDKKGRPSFEEEEKALSRRMGQGERNFELYKAF
HHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCCHHHHHHH
DDRMKKEYGYVFYPEAYAELQALCNDCFPTDEAFYEKAKDMNKTLMQLDGKDFPQAEFAY
HHHHHHHCCEEECCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHH
YIQRCPFSTKTYAGDFMQEIYDLFIRDIVTTAERKNLETKHPEIPHLMQEYRDGILLFEV
HHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHCCCEEEEEE
SNREIWSKPSAQQKVLEAKWIADLNKKYPVTVNWKLLKKLKK
CCCHHCCCCCHHHHHHHHHHHHHCCCCCCEEECHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA