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The map label for this gene is map [H]

Identifier: 150008963

GI number: 150008963

Start: 2779034

End: 2779819

Strand: Reverse

Name: map [H]

Synonym: BDI_2359

Alternate gene names: 150008963

Gene position: 2779819-2779034 (Counterclockwise)

Preceding gene: 150008964

Following gene: 150008962

Centisome position: 57.78

GC content: 44.4

Gene sequence:

>786_bases
ATGATCTATTTAAAGACAGATGAAGAGATTGAGTTGATGCGTGAGGCTAATCAACTGGTAGGTAAGACACTTGGCGAGGT
AGCTAAGCATATTGTCCCCGGAGTCTCCACACTTCAACTTGATAAGATTGCGGAAGAGTTCATTAGAGATAATGGTGCTG
TTCCGGCTTTTTTGGGATATGGTGGTTTCCCTAATTCAATATGTGCCTCAGTGAATGATCAGGTGGTGCATGGTATTCCT
TCTTCTAAGATGATCTTGAAAGAGGGTGACGTGATCTCTGTGGATTGTGGGACGATATTGAATGGTTTTGTCGGTGACTC
CGCTTACACTTTCTGTGTAGGTGAGGTTGCGCCGGAAGTGAAGAAATTGTTGAAAGCGACGAAGGATTCACTTTATTTAG
GTATCCAATGTGCTGTTGAAGGTCACCGTTTGGGTGATATCAGTAATGCGATTCAGACTTATTGCGAGTCTCAAGGTTAC
TCTGTCGTAAGAGAGCTGGTGGGACATGGTATAGGTCGGAAAATGCATGAGGAACCGGAAGTGCCTAATTATGGCAGACG
TGGATGCGGACCGTTATTGCGTAACGGAATGTGTATCTGCATCGAGCCGATGATCAACATGGGAAGCAAGAACGTTGCAT
TTGAGAAAGACGGATGGACGGTTCGCACAAAGGACAGAAAGCCTTCTGCTCATTTCGAGCATTGTATCGCTATACGTCCG
GATGGTCCCCAGATCTTATCTTCATTTAAGTTTTTAGAGGAAGTTCTAGGAGAAAACGCAATTTAA

Upstream 100 bases:

>100_bases
CAGCAAGTTGAAAGTCATTTGCTAATGCGTCATTATGACGGTTTGTTGAAGTCAGGAAGAATTAAAGGCCGTACAGGCTC
TGTTGCCGCTTATTAATAGA

Downstream 100 bases:

>100_bases
TTGGATTTATATGGCTAAACAATCAGCAATAGAGAAAGATGGAGTAATTGTAGAAGCATTGTCAAACGCGATGTTTCGTG
TAGAATTGGAGAACGGACAT

Product: methionine aminopeptidase, type I

Products: NA

Alternate protein names: MAP; Peptidase M [H]

Number of amino acids: Translated: 261; Mature: 261

Protein sequence:

>261_residues
MIYLKTDEEIELMREANQLVGKTLGEVAKHIVPGVSTLQLDKIAEEFIRDNGAVPAFLGYGGFPNSICASVNDQVVHGIP
SSKMILKEGDVISVDCGTILNGFVGDSAYTFCVGEVAPEVKKLLKATKDSLYLGIQCAVEGHRLGDISNAIQTYCESQGY
SVVRELVGHGIGRKMHEEPEVPNYGRRGCGPLLRNGMCICIEPMINMGSKNVAFEKDGWTVRTKDRKPSAHFEHCIAIRP
DGPQILSSFKFLEEVLGENAI

Sequences:

>Translated_261_residues
MIYLKTDEEIELMREANQLVGKTLGEVAKHIVPGVSTLQLDKIAEEFIRDNGAVPAFLGYGGFPNSICASVNDQVVHGIP
SSKMILKEGDVISVDCGTILNGFVGDSAYTFCVGEVAPEVKKLLKATKDSLYLGIQCAVEGHRLGDISNAIQTYCESQGY
SVVRELVGHGIGRKMHEEPEVPNYGRRGCGPLLRNGMCICIEPMINMGSKNVAFEKDGWTVRTKDRKPSAHFEHCIAIRP
DGPQILSSFKFLEEVLGENAI
>Mature_261_residues
MIYLKTDEEIELMREANQLVGKTLGEVAKHIVPGVSTLQLDKIAEEFIRDNGAVPAFLGYGGFPNSICASVNDQVVHGIP
SSKMILKEGDVISVDCGTILNGFVGDSAYTFCVGEVAPEVKKLLKATKDSLYLGIQCAVEGHRLGDISNAIQTYCESQGY
SVVRELVGHGIGRKMHEEPEVPNYGRRGCGPLLRNGMCICIEPMINMGSKNVAFEKDGWTVRTKDRKPSAHFEHCIAIRP
DGPQILSSFKFLEEVLGENAI

Specific function: Removes the amino-terminal methionine from nascent proteins [H]

COG id: COG0024

COG function: function code J; Methionine aminopeptidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M24A family [H]

Homologues:

Organism=Homo sapiens, GI164420681, Length=246, Percent_Identity=37.3983739837398, Blast_Score=159, Evalue=3e-39,
Organism=Homo sapiens, GI40385867, Length=248, Percent_Identity=35.0806451612903, Blast_Score=150, Evalue=2e-36,
Organism=Escherichia coli, GI1786364, Length=250, Percent_Identity=44.4, Blast_Score=218, Evalue=3e-58,
Organism=Caenorhabditis elegans, GI71996291, Length=248, Percent_Identity=37.5, Blast_Score=157, Evalue=7e-39,
Organism=Saccharomyces cerevisiae, GI6323273, Length=248, Percent_Identity=34.2741935483871, Blast_Score=152, Evalue=6e-38,
Organism=Saccharomyces cerevisiae, GI6319380, Length=203, Percent_Identity=31.0344827586207, Blast_Score=66, Evalue=7e-12,
Organism=Drosophila melanogaster, GI21355531, Length=241, Percent_Identity=38.5892116182573, Blast_Score=164, Evalue=7e-41,
Organism=Drosophila melanogaster, GI24583427, Length=244, Percent_Identity=36.4754098360656, Blast_Score=156, Evalue=1e-38,

Paralogues:

None

Copy number: 3,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001714
- InterPro:   IPR000994
- InterPro:   IPR002467 [H]

Pfam domain/function: PF00557 Peptidase_M24 [H]

EC number: =3.4.11.18 [H]

Molecular weight: Translated: 28486; Mature: 28486

Theoretical pI: Translated: 5.63; Mature: 5.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.4 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
6.1 %Cys+Met (Translated Protein)
3.4 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
6.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIYLKTDEEIELMREANQLVGKTLGEVAKHIVPGVSTLQLDKIAEEFIRDNGAVPAFLGY
CEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCEEEECC
GGFPNSICASVNDQVVHGIPSSKMILKEGDVISVDCGTILNGFVGDSAYTFCVGEVAPEV
CCCCHHHHHCCCCHHHCCCCCCCEEEECCCEEEEEHHHHHHHHCCCCHHHHHHHHHHHHH
KKLLKATKDSLYLGIQCAVEGHRLGDISNAIQTYCESQGYSVVRELVGHGIGRKMHEEPE
HHHHHHHHCCEEEEEEEEECCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCC
VPNYGRRGCGPLLRNGMCICIEPMINMGSKNVAFEKDGWTVRTKDRKPSAHFEHCIAIRP
CCCCCCCCCCHHHHCCCEEEEEHHHCCCCCCCEEECCCCEEEECCCCCCCCCCEEEEECC
DGPQILSSFKFLEEVLGENAI
CCHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MIYLKTDEEIELMREANQLVGKTLGEVAKHIVPGVSTLQLDKIAEEFIRDNGAVPAFLGY
CEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCEEEECC
GGFPNSICASVNDQVVHGIPSSKMILKEGDVISVDCGTILNGFVGDSAYTFCVGEVAPEV
CCCCHHHHHCCCCHHHCCCCCCCEEEECCCEEEEEHHHHHHHHCCCCHHHHHHHHHHHHH
KKLLKATKDSLYLGIQCAVEGHRLGDISNAIQTYCESQGYSVVRELVGHGIGRKMHEEPE
HHHHHHHHCCEEEEEEEEECCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCC
VPNYGRRGCGPLLRNGMCICIEPMINMGSKNVAFEKDGWTVRTKDRKPSAHFEHCIAIRP
CCCCCCCCCCHHHHCCCEEEEEHHHCCCCCCCEEECCCCEEEECCCCCCCCCCEEEEECC
DGPQILSSFKFLEEVLGENAI
CCHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11466286 [H]