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The map label for this gene is ttcA [H]

Identifier: 150008723

GI number: 150008723

Start: 2494832

End: 2495578

Strand: Reverse

Name: ttcA [H]

Synonym: BDI_2113

Alternate gene names: 150008723

Gene position: 2495578-2494832 (Counterclockwise)

Preceding gene: 150008729

Following gene: 150008722

Centisome position: 51.87

GC content: 46.99

Gene sequence:

>747_bases
ATGGCAAAATTGACAGAGGACGAACGTTTGTTTCGCAAGATAGAGGATAAGATAAAGAGAGCGATTTTCGACTATGGCTT
GATCAATGATGGCGACCGGATCTTGGTCGGGTTGTCCGGAGGAAAAGATTCCTTGGCCTTGGTGGATTTACTGGGGCGCA
GGTCGAAAATCTATTGTCCTCGGTTTGAGGTCGTGGTAGCGCATATCGTGATGACGAATATCCCTTATTGTTCGGATCGG
GAATATCTTAGAAGTTGCGCGGAGGAGCATGATTTGCCTTTCATTGTCCATGAGACAAGTTTCGATCCTTCTACGGACAC
TCGCAAATCCCCCTGCTTTTTATGCTCTTGGACTCGCCGGAAAGCTTTGTTTGAGATCGCTAAGGCGCATAAATGCAATA
AGATCGCTTTAGGCCATCATCAAGATGATATCCTTGAGACGCTGTTGATGAACCTGACCCACCAAGGGGCTTTCGGGACA
ATGCCTCCCCGGTTGAGAATGGATAAGTTTGATATGGAGATCATCCGTCCGATGTGTCTGGTGGAAGAGAGGGAGTTGAT
TCAGGTCGCCGCATGGAAAGGGTACCGGAAACAATTGAAGAACTGTCCTTATGAGTCGGGTTCCAGTCGTTCGGATATGA
AAGAGCTGCTGAGAAGTCTGGAAGCGATCAATCCGGAGGCTCGTTACAGTCTTTGGGGGAGCATGACGAATATACAAGAA
GATTATTTACCTCGAAAAATAAGATAA

Upstream 100 bases:

>100_bases
GATTATATATAGTTATGCAGTTTCAAAGATAAGAATATTTTTGTAGAGGCATACAAATCGAAAAGATAAATATATAATTT
TGCGCCCGTAAAGGAAGTAT

Downstream 100 bases:

>100_bases
TATGCAAAGTGTTTATACGATTTTATTGTTGATCGTGTCTAATATTTTTATGACATGCGCTTGGTATGGTCATTTGAAGA
TGAAGCAACAGTTTAGCTGG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 248; Mature: 247

Protein sequence:

>248_residues
MAKLTEDERLFRKIEDKIKRAIFDYGLINDGDRILVGLSGGKDSLALVDLLGRRSKIYCPRFEVVVAHIVMTNIPYCSDR
EYLRSCAEEHDLPFIVHETSFDPSTDTRKSPCFLCSWTRRKALFEIAKAHKCNKIALGHHQDDILETLLMNLTHQGAFGT
MPPRLRMDKFDMEIIRPMCLVEERELIQVAAWKGYRKQLKNCPYESGSSRSDMKELLRSLEAINPEARYSLWGSMTNIQE
DYLPRKIR

Sequences:

>Translated_248_residues
MAKLTEDERLFRKIEDKIKRAIFDYGLINDGDRILVGLSGGKDSLALVDLLGRRSKIYCPRFEVVVAHIVMTNIPYCSDR
EYLRSCAEEHDLPFIVHETSFDPSTDTRKSPCFLCSWTRRKALFEIAKAHKCNKIALGHHQDDILETLLMNLTHQGAFGT
MPPRLRMDKFDMEIIRPMCLVEERELIQVAAWKGYRKQLKNCPYESGSSRSDMKELLRSLEAINPEARYSLWGSMTNIQE
DYLPRKIR
>Mature_247_residues
AKLTEDERLFRKIEDKIKRAIFDYGLINDGDRILVGLSGGKDSLALVDLLGRRSKIYCPRFEVVVAHIVMTNIPYCSDRE
YLRSCAEEHDLPFIVHETSFDPSTDTRKSPCFLCSWTRRKALFEIAKAHKCNKIALGHHQDDILETLLMNLTHQGAFGTM
PPRLRMDKFDMEIIRPMCLVEERELIQVAAWKGYRKQLKNCPYESGSSRSDMKELLRSLEAINPEARYSLWGSMTNIQED
YLPRKIR

Specific function: Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) [H]

COG id: COG0037

COG function: function code D; Predicted ATPase of the PP-loop superfamily implicated in cell cycle control

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the TtcA family [H]

Homologues:

Organism=Escherichia coli, GI1787606, Length=241, Percent_Identity=29.8755186721992, Blast_Score=108, Evalue=4e-25,
Organism=Caenorhabditis elegans, GI193211090, Length=247, Percent_Identity=29.1497975708502, Blast_Score=86, Evalue=1e-17,
Organism=Drosophila melanogaster, GI24651972, Length=230, Percent_Identity=26.5217391304348, Blast_Score=66, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012089
- InterPro:   IPR014729
- InterPro:   IPR011063 [H]

Pfam domain/function: PF01171 ATP_bind_3 [H]

EC number: NA

Molecular weight: Translated: 28774; Mature: 28643

Theoretical pI: Translated: 8.21; Mature: 8.21

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.2 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
6.9 %Cys+Met (Translated Protein)
3.2 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
6.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKLTEDERLFRKIEDKIKRAIFDYGLINDGDRILVGLSGGKDSLALVDLLGRRSKIYCP
CCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCHHHHHHHHCCCCCCCCC
RFEVVVAHIVMTNIPYCSDREYLRSCAEEHDLPFIVHETSFDPSTDTRKSPCFLCSWTRR
HHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCEEEEHHHHH
KALFEIAKAHKCNKIALGHHQDDILETLLMNLTHQGAFGTMPPRLRMDKFDMEIIRPMCL
HHHHHHHHHHCCCCEECCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHH
VEERELIQVAAWKGYRKQLKNCPYESGSSRSDMKELLRSLEAINPEARYSLWGSMTNIQE
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
DYLPRKIR
HCCCCCCC
>Mature Secondary Structure 
AKLTEDERLFRKIEDKIKRAIFDYGLINDGDRILVGLSGGKDSLALVDLLGRRSKIYCP
CCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCHHHHHHHHCCCCCCCCC
RFEVVVAHIVMTNIPYCSDREYLRSCAEEHDLPFIVHETSFDPSTDTRKSPCFLCSWTRR
HHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCEEEEHHHHH
KALFEIAKAHKCNKIALGHHQDDILETLLMNLTHQGAFGTMPPRLRMDKFDMEIIRPMCL
HHHHHHHHHHCCCCEECCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHH
VEERELIQVAAWKGYRKQLKNCPYESGSSRSDMKELLRSLEAINPEARYSLWGSMTNIQE
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
DYLPRKIR
HCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA