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The map label for this gene is dnaX [H]

Identifier: 150008698

GI number: 150008698

Start: 2470376

End: 2472136

Strand: Reverse

Name: dnaX [H]

Synonym: BDI_2088

Alternate gene names: 150008698

Gene position: 2472136-2470376 (Counterclockwise)

Preceding gene: 150008701

Following gene: 150008694

Centisome position: 51.38

GC content: 48.15

Gene sequence:

>1761_bases
ATGGATAATTATATTGTATCGGCAAGAAAATATCGCCCGTCCACTTTCCGGAGTGTAGTAGGGCAGAAGTCTCTTACCAC
TACGCTGAAAAACGCGATACAAAGTAACAAATTAGCGCATGCTTACCTGTTTTGCGGTCCTCGTGGAGTAGGAAAGACCT
CGTGTGCCCGTATCTTTGCGAAGACGATCAATTGCTTGAATCCGACGGCGGATGGCGAGGCTTGCAATGCGTGCGAGTCG
TGCCGGGCTTTCAATGAGCAGCGTTCTTACAATATCCATGAACTGGATGCCGCCTCGAATAACTCGGTGGACGATATCCG
TACCTTGATCGACCAAGTGCGTATCCCGCCTCCAATCGGTAAATACAAAGTCTTCATTATTGACGAGGTCCATATGTTGA
CAACCGCCGCTTTCAACGCATTCTTGAAGACATTGGAGGAACCTCCGCATCATGCTCTCTTTATCTTGGCTACGACCGAG
AAGCACAAGGTGCTTCCCACGATCCTTTCCCGTTGTCAGATCTATGATTTCTCCCGTATATCCATCGCCGACATGGTGGA
GCATTTGCAATATGTCTCTTCGCAAGAGGGGGTAACTGCGGAACCGGAAGCCTTGAACGTGATCGCTCAGAAGGCGGATG
GAGGTATGCGCGACGCTTTGTCTATCTTTGACCAAGTGGTAAGTTTCACGAATGGCAATATCACGTATCAAGCGGTTATC
GATAACTTGAACGTGCTGGATTATGAGTATTATTTTCGTCTGACAGATGCGATCTTATCCGGCAATGTGCGGGCTTCTTT
ATTGATCTTGAATGAGATATTAGGCAAAGGATTCGACGGGCAGAATATCATAACCGGTTTGGCTGGGCATTTCCGGGACT
TATTGGTATGCCGGGATGAGTCCACCTTGGTGCTATTCGAGGTGGGAGCTTCTATACGGGAACGATATAAGGAGATGGCG
AAACATTGTCCGGATCAACTTCTGTTCAAGGCGATAGAGCTAGCGAATACGTGCGATTTGAATTACCGTGCCAGCCGCAA
TAAGCGTCTTTTATTGGAATTGACGTTGATTCAGCTCTGTCAATTAACACAGGTGGCCGTCGACGATAAAAAAAAAGCGT
TAATTGAGCCGATTGCTGGGACGAATCCGTCTTCTCAAGCGGTGAATAGCGGGCAGCCCCAACAGCCGCCTCAAGCTCCT
TCAGTTACGGCAGCGGCCGGTGCTCCACAAGTTATGAGTACGCACATGCCGAGCTCGGTTCCTGCGCCACCTCCGTCTAC
AGCGCCTAATCCGGCTCGTAAAACGGCTCGTCCGATGGGGATCTCCATGAAGGAGATCGGAGTGGAGAAGCCTAAGCAAC
AAACCGTTCAACAAGCGACAACGAACGTAAAGGAGGTAGTAACTCCCTTTGACAATGATTCCTTGGTTCGTGAATGGGAT
AATTACGCCGCAACGATTGACAAGAAAGTGTATCTTAAGAATACGATGATCAATTGCAAGCCTACCTTGCAAGAGAATTA
TTATTTCGAGGTAGCTGTACATAACCCGGGGCAGCAAGAGGAATTGATCAATAATGCGATCCATATCCTGCCATTTCTCC
GCCAGCATCTTAATAACAGCCGCATCCAGATGCGTGTCCGGATCGTAGAGGGAAATGAGAAGCACTTGGCTTATACATCC
ACGGAGAAGCTAGAGCTGCTGATGAAGATAAATCCTACCTTGGGTCGTTTGAGGGATGAGTTTAATTTGACGTTAGATTA
A

Upstream 100 bases:

>100_bases
ACTTTATGTAAAACTCTTTTATGCGTGACATCAGAACATCGTTTTCGCGAAGATAATGAATTATTTTGTTTATCTTTGTC
TTATCAATAAAAAGCAGAGA

Downstream 100 bases:

>100_bases
GTAGATGTGCTAAAGATCCCAAGAAGGGATCTTTAGTCTTATTTTTTATTCCTTTGTCTCAAGATAAACCACTTGAGTTT
GCAAATACTCCTCAAGTCCA

Product: DNA polymerase III subunit gamma/tau

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 586; Mature: 586

Protein sequence:

>586_residues
MDNYIVSARKYRPSTFRSVVGQKSLTTTLKNAIQSNKLAHAYLFCGPRGVGKTSCARIFAKTINCLNPTADGEACNACES
CRAFNEQRSYNIHELDAASNNSVDDIRTLIDQVRIPPPIGKYKVFIIDEVHMLTTAAFNAFLKTLEEPPHHALFILATTE
KHKVLPTILSRCQIYDFSRISIADMVEHLQYVSSQEGVTAEPEALNVIAQKADGGMRDALSIFDQVVSFTNGNITYQAVI
DNLNVLDYEYYFRLTDAILSGNVRASLLILNEILGKGFDGQNIITGLAGHFRDLLVCRDESTLVLFEVGASIRERYKEMA
KHCPDQLLFKAIELANTCDLNYRASRNKRLLLELTLIQLCQLTQVAVDDKKKALIEPIAGTNPSSQAVNSGQPQQPPQAP
SVTAAAGAPQVMSTHMPSSVPAPPPSTAPNPARKTARPMGISMKEIGVEKPKQQTVQQATTNVKEVVTPFDNDSLVREWD
NYAATIDKKVYLKNTMINCKPTLQENYYFEVAVHNPGQQEELINNAIHILPFLRQHLNNSRIQMRVRIVEGNEKHLAYTS
TEKLELLMKINPTLGRLRDEFNLTLD

Sequences:

>Translated_586_residues
MDNYIVSARKYRPSTFRSVVGQKSLTTTLKNAIQSNKLAHAYLFCGPRGVGKTSCARIFAKTINCLNPTADGEACNACES
CRAFNEQRSYNIHELDAASNNSVDDIRTLIDQVRIPPPIGKYKVFIIDEVHMLTTAAFNAFLKTLEEPPHHALFILATTE
KHKVLPTILSRCQIYDFSRISIADMVEHLQYVSSQEGVTAEPEALNVIAQKADGGMRDALSIFDQVVSFTNGNITYQAVI
DNLNVLDYEYYFRLTDAILSGNVRASLLILNEILGKGFDGQNIITGLAGHFRDLLVCRDESTLVLFEVGASIRERYKEMA
KHCPDQLLFKAIELANTCDLNYRASRNKRLLLELTLIQLCQLTQVAVDDKKKALIEPIAGTNPSSQAVNSGQPQQPPQAP
SVTAAAGAPQVMSTHMPSSVPAPPPSTAPNPARKTARPMGISMKEIGVEKPKQQTVQQATTNVKEVVTPFDNDSLVREWD
NYAATIDKKVYLKNTMINCKPTLQENYYFEVAVHNPGQQEELINNAIHILPFLRQHLNNSRIQMRVRIVEGNEKHLAYTS
TEKLELLMKINPTLGRLRDEFNLTLD
>Mature_586_residues
MDNYIVSARKYRPSTFRSVVGQKSLTTTLKNAIQSNKLAHAYLFCGPRGVGKTSCARIFAKTINCLNPTADGEACNACES
CRAFNEQRSYNIHELDAASNNSVDDIRTLIDQVRIPPPIGKYKVFIIDEVHMLTTAAFNAFLKTLEEPPHHALFILATTE
KHKVLPTILSRCQIYDFSRISIADMVEHLQYVSSQEGVTAEPEALNVIAQKADGGMRDALSIFDQVVSFTNGNITYQAVI
DNLNVLDYEYYFRLTDAILSGNVRASLLILNEILGKGFDGQNIITGLAGHFRDLLVCRDESTLVLFEVGASIRERYKEMA
KHCPDQLLFKAIELANTCDLNYRASRNKRLLLELTLIQLCQLTQVAVDDKKKALIEPIAGTNPSSQAVNSGQPQQPPQAP
SVTAAAGAPQVMSTHMPSSVPAPPPSTAPNPARKTARPMGISMKEIGVEKPKQQTVQQATTNVKEVVTPFDNDSLVREWD
NYAATIDKKVYLKNTMINCKPTLQENYYFEVAVHNPGQQEELINNAIHILPFLRQHLNNSRIQMRVRIVEGNEKHLAYTS
TEKLELLMKINPTLGRLRDEFNLTLD

Specific function: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria [H]

COG id: COG2812

COG function: function code L; DNA polymerase III, gamma/tau subunits

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI6677723, Length=250, Percent_Identity=26, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI194306571, Length=250, Percent_Identity=26, Blast_Score=82, Evalue=2e-15,
Organism=Homo sapiens, GI194306567, Length=250, Percent_Identity=26, Blast_Score=82, Evalue=2e-15,
Organism=Homo sapiens, GI31563534, Length=304, Percent_Identity=23.3552631578947, Blast_Score=74, Evalue=5e-13,
Organism=Homo sapiens, GI4506491, Length=297, Percent_Identity=22.5589225589226, Blast_Score=72, Evalue=2e-12,
Organism=Homo sapiens, GI31881687, Length=297, Percent_Identity=22.5589225589226, Blast_Score=72, Evalue=2e-12,
Organism=Escherichia coli, GI1786676, Length=358, Percent_Identity=37.1508379888268, Blast_Score=253, Evalue=2e-68,
Organism=Caenorhabditis elegans, GI17541988, Length=356, Percent_Identity=22.1910112359551, Blast_Score=79, Evalue=8e-15,
Organism=Caenorhabditis elegans, GI17554730, Length=219, Percent_Identity=26.4840182648402, Blast_Score=75, Evalue=9e-14,
Organism=Caenorhabditis elegans, GI71986063, Length=246, Percent_Identity=23.9837398373984, Blast_Score=65, Evalue=8e-11,
Organism=Saccharomyces cerevisiae, GI6324478, Length=283, Percent_Identity=26.1484098939929, Blast_Score=88, Evalue=5e-18,
Organism=Saccharomyces cerevisiae, GI6324039, Length=216, Percent_Identity=27.3148148148148, Blast_Score=84, Evalue=5e-17,
Organism=Saccharomyces cerevisiae, GI6322528, Length=299, Percent_Identity=23.0769230769231, Blast_Score=75, Evalue=3e-14,
Organism=Drosophila melanogaster, GI17647857, Length=296, Percent_Identity=27.7027027027027, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI18859927, Length=224, Percent_Identity=26.3392857142857, Blast_Score=78, Evalue=1e-14,
Organism=Drosophila melanogaster, GI19921076, Length=220, Percent_Identity=25, Blast_Score=67, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR003959
- InterPro:   IPR001270
- InterPro:   IPR008921
- InterPro:   IPR022754
- InterPro:   IPR012763 [H]

Pfam domain/function: PF00004 AAA; PF12169 DNA_pol3_gamma3 [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 65318; Mature: 65318

Theoretical pI: Translated: 7.51; Mature: 7.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDNYIVSARKYRPSTFRSVVGQKSLTTTLKNAIQSNKLAHAYLFCGPRGVGKTSCARIFA
CCCCEEEHHHCCCHHHHHHHCCHHHHHHHHHHHHCCCCEEEEEEECCCCCCHHHHHHHHH
KTINCLNPTADGEACNACESCRAFNEQRSYNIHELDAASNNSVDDIRTLIDQVRIPPPIG
HHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCEEECCCCCCCHHHHHHHHHHCCCCCCCC
KYKVFIIDEVHMLTTAAFNAFLKTLEEPPHHALFILATTEKHKVLPTILSRCQIYDFSRI
CEEEEEEECHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCHHHHHHHHHHCCCCCCCC
SIADMVEHLQYVSSQEGVTAEPEALNVIAQKADGGMRDALSIFDQVVSFTNGNITYQAVI
CHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCEEEEEEE
DNLNVLDYEYYFRLTDAILSGNVRASLLILNEILGKGFDGQNIITGLAGHFRDLLVCRDE
CCCCEEEHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHEEEECCC
STLVLFEVGASIRERYKEMAKHCPDQLLFKAIELANTCDLNYRASRNKRLLLELTLIQLC
CEEEEEECCHHHHHHHHHHHHHCHHHHHHHHHHHHHHCCCCEECCCCCEEEEHHHHHHHH
QLTQVAVDDKKKALIEPIAGTNPSSQAVNSGQPQQPPQAPSVTAAAGAPQVMSTHMPSSV
HHHHHHHCCHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCEECCCCCHHHHHCCCCCC
PAPPPSTAPNPARKTARPMGISMKEIGVEKPKQQTVQQATTNVKEVVTPFDNDSLVREWD
CCCCCCCCCCCHHHCCCCCCCCHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHH
NYAATIDKKVYLKNTMINCKPTLQENYYFEVAVHNPGQQEELINNAIHILPFLRQHLNNS
HHHHHHCCEEEEECCEECCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCC
RIQMRVRIVEGNEKHLAYTSTEKLELLMKINPTLGRLRDEFNLTLD
EEEEEEEEEECCCCEEEEECHHHEEEEEEECCHHHHHHHCCCCCCC
>Mature Secondary Structure
MDNYIVSARKYRPSTFRSVVGQKSLTTTLKNAIQSNKLAHAYLFCGPRGVGKTSCARIFA
CCCCEEEHHHCCCHHHHHHHCCHHHHHHHHHHHHCCCCEEEEEEECCCCCCHHHHHHHHH
KTINCLNPTADGEACNACESCRAFNEQRSYNIHELDAASNNSVDDIRTLIDQVRIPPPIG
HHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCEEECCCCCCCHHHHHHHHHHCCCCCCCC
KYKVFIIDEVHMLTTAAFNAFLKTLEEPPHHALFILATTEKHKVLPTILSRCQIYDFSRI
CEEEEEEECHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCHHHHHHHHHHCCCCCCCC
SIADMVEHLQYVSSQEGVTAEPEALNVIAQKADGGMRDALSIFDQVVSFTNGNITYQAVI
CHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCEEEEEEE
DNLNVLDYEYYFRLTDAILSGNVRASLLILNEILGKGFDGQNIITGLAGHFRDLLVCRDE
CCCCEEEHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHEEEECCC
STLVLFEVGASIRERYKEMAKHCPDQLLFKAIELANTCDLNYRASRNKRLLLELTLIQLC
CEEEEEECCHHHHHHHHHHHHHCHHHHHHHHHHHHHHCCCCEECCCCCEEEEHHHHHHHH
QLTQVAVDDKKKALIEPIAGTNPSSQAVNSGQPQQPPQAPSVTAAAGAPQVMSTHMPSSV
HHHHHHHCCHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCEECCCCCHHHHHCCCCCC
PAPPPSTAPNPARKTARPMGISMKEIGVEKPKQQTVQQATTNVKEVVTPFDNDSLVREWD
CCCCCCCCCCCHHHCCCCCCCCHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHH
NYAATIDKKVYLKNTMINCKPTLQENYYFEVAVHNPGQQEELINNAIHILPFLRQHLNNS
HHHHHHCCEEEEECCEECCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCC
RIQMRVRIVEGNEKHLAYTSTEKLELLMKINPTLGRLRDEFNLTLD
EEEEEEEEEECCCCEEEEECHHHEEEEEEECCHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2124672; 7584024; 9384377; 2452406; 2468993; 1698458 [H]