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The map label for this gene is aroC

Identifier: 150008692

GI number: 150008692

Start: 2465411

End: 2466487

Strand: Direct

Name: aroC

Synonym: BDI_2082

Alternate gene names: 150008692

Gene position: 2465411-2466487 (Clockwise)

Preceding gene: 150008691

Following gene: 150008693

Centisome position: 51.24

GC content: 49.03

Gene sequence:

>1077_bases
GTGAATACTTTTGGTAATATTTATAGATTAACATCGTTCGGCGAATCGCACGGTCCCGGTATCGGCGGCGTGATCGACGG
ATGCCCAGCCGGGATCGAATTAGATACGGCATTCATCCAGCAAGAGCTGAACCGTCGTAAACCGGGACAATCCCGTATCA
CGACCCCCCGTAAAGAGGATGATGAGGTACAGTTTCTTTCCGGTATCTACGAGGGAAAGACAACCGGTACGCCGATAGGT
TTCATCATCTGGAACAAAAACCAACATTCCTCGGACTATGACAATATGAAAACGGTTTACCGTCCTTCCCATGCTGATTA
TACCTATCAAACGAAATATGGAATCCGTGATCCCCGTGGAGGTGGACGTTCGTCCGCCCGGGAAACGATCGCTCGTTGCG
TGGCTGGGGCTATCGCTAAACTCGCCCTTAAGCAATACGGCATACAGATTCAAGCTTATACCTCGCAGGTCGGCCCGATC
AAATTAGCGGGTAGTTACCAAGATTATGATTTAAGCTTGACGGAAAAGAGCGATGTACGTTGCCCGGACCCGAAGACCGC
CTCAGAGATGGAAACCTTGATCGCTGAGGTCAAATCAAAAGGAGATACGATCGGCGGTGTTATTACCTGTGTGGCGAAAG
GGGTTCCCGTCGGATTGGGAGAGCCTGTGTTCGGCAAGTTACATGCCGCGTTGGGACATGCGATGCTTACGATCAACGCC
GTGAAAGGCTTCGAGTATGGAGACGGATTCAACGCCGCCTTCTTCCGCGGATCGGAAAGGAACGATCGCTTTTTCAATGA
TAACGGGCATATCAATACTCGTACCAATAATTCCGGCGGTATCCAAGGAGGGATATCCAACGGACAAGATATTTATTTCC
GGGTAGCCTTTAAATCGGTCGCTACGATCTTGATGGAACAAGAAACGGTTAATATGGAGGGAGAGGATACGATATTAAAG
GCACGCGGACGTCATGATCCATGCGTATTGCCTCGTGCGGTACCTATCGTCGAGTCTATGACCGCCATGACTTTATTGGA
TTATTTATTGATCCAAAAGACACGGGAAAACTTTTAA

Upstream 100 bases:

>100_bases
AAGGGAAATTGAGAATTGAAAATTGAAAATTAGGAGAAGTGCCTAATCATCGGCTTTTGATTCTCAATTTTCAGTTTTCA
ATTTTCAATTAGACAAAACG

Downstream 100 bases:

>100_bases
GACTAATTCTATATGGCTTGGATTCTGTTAATTATAGCCGGATTATTCGAGATCGGCTGGCCGCTGGGCTTTAAATTAGC
AAGTATGCATTCCAAATATT

Product: chorismate synthase

Products: NA

Alternate protein names: 5-enolpyruvylshikimate-3-phosphate phospholyase

Number of amino acids: Translated: 358; Mature: 358

Protein sequence:

>358_residues
MNTFGNIYRLTSFGESHGPGIGGVIDGCPAGIELDTAFIQQELNRRKPGQSRITTPRKEDDEVQFLSGIYEGKTTGTPIG
FIIWNKNQHSSDYDNMKTVYRPSHADYTYQTKYGIRDPRGGGRSSARETIARCVAGAIAKLALKQYGIQIQAYTSQVGPI
KLAGSYQDYDLSLTEKSDVRCPDPKTASEMETLIAEVKSKGDTIGGVITCVAKGVPVGLGEPVFGKLHAALGHAMLTINA
VKGFEYGDGFNAAFFRGSERNDRFFNDNGHINTRTNNSGGIQGGISNGQDIYFRVAFKSVATILMEQETVNMEGEDTILK
ARGRHDPCVLPRAVPIVESMTAMTLLDYLLIQKTRENF

Sequences:

>Translated_358_residues
MNTFGNIYRLTSFGESHGPGIGGVIDGCPAGIELDTAFIQQELNRRKPGQSRITTPRKEDDEVQFLSGIYEGKTTGTPIG
FIIWNKNQHSSDYDNMKTVYRPSHADYTYQTKYGIRDPRGGGRSSARETIARCVAGAIAKLALKQYGIQIQAYTSQVGPI
KLAGSYQDYDLSLTEKSDVRCPDPKTASEMETLIAEVKSKGDTIGGVITCVAKGVPVGLGEPVFGKLHAALGHAMLTINA
VKGFEYGDGFNAAFFRGSERNDRFFNDNGHINTRTNNSGGIQGGISNGQDIYFRVAFKSVATILMEQETVNMEGEDTILK
ARGRHDPCVLPRAVPIVESMTAMTLLDYLLIQKTRENF
>Mature_358_residues
MNTFGNIYRLTSFGESHGPGIGGVIDGCPAGIELDTAFIQQELNRRKPGQSRITTPRKEDDEVQFLSGIYEGKTTGTPIG
FIIWNKNQHSSDYDNMKTVYRPSHADYTYQTKYGIRDPRGGGRSSARETIARCVAGAIAKLALKQYGIQIQAYTSQVGPI
KLAGSYQDYDLSLTEKSDVRCPDPKTASEMETLIAEVKSKGDTIGGVITCVAKGVPVGLGEPVFGKLHAALGHAMLTINA
VKGFEYGDGFNAAFFRGSERNDRFFNDNGHINTRTNNSGGIQGGISNGQDIYFRVAFKSVATILMEQETVNMEGEDTILK
ARGRHDPCVLPRAVPIVESMTAMTLLDYLLIQKTRENF

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; seventh step. [C]

COG id: COG0082

COG function: function code E; Chorismate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the chorismate synthase family

Homologues:

Organism=Escherichia coli, GI1788669, Length=355, Percent_Identity=49.2957746478873, Blast_Score=327, Evalue=5e-91,
Organism=Saccharomyces cerevisiae, GI6321290, Length=369, Percent_Identity=50.6775067750677, Blast_Score=367, Evalue=1e-102,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): AROC_PARD8 (A6LDP9)

Other databases:

- EMBL:   CP000140
- RefSeq:   YP_001303435.1
- ProteinModelPortal:   A6LDP9
- SMR:   A6LDP9
- STRING:   A6LDP9
- GeneID:   5307231
- GenomeReviews:   CP000140_GR
- KEGG:   pdi:BDI_2082
- eggNOG:   COG0082
- HOGENOM:   HBG292336
- OMA:   TATIGKE
- ProtClustDB:   PRK05382
- BioCyc:   PDIS435591:BDI_2082-MONOMER
- HAMAP:   MF_00300_B
- InterPro:   IPR000453
- InterPro:   IPR020541
- PANTHER:   PTHR21085
- PIRSF:   PIRSF001456
- TIGRFAMs:   TIGR00033

Pfam domain/function: PF01264 Chorismate_synt; SSF103263 Chorismate_synth

EC number: =4.2.3.5

Molecular weight: Translated: 39156; Mature: 39156

Theoretical pI: Translated: 7.53; Mature: 7.53

Prosite motif: PS00787 CHORISMATE_SYNTHASE_1; PS00788 CHORISMATE_SYNTHASE_2; PS00789 CHORISMATE_SYNTHASE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTFGNIYRLTSFGESHGPGIGGVIDGCPAGIELDTAFIQQELNRRKPGQSRITTPRKED
CCCCCCEEEEECCCCCCCCCCCCHHCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCC
DEVQFLSGIYEGKTTGTPIGFIIWNKNQHSSDYDNMKTVYRPSHADYTYQTKYGIRDPRG
CHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCCCCCHHHCCCCCCCEEEEEECCCCCCCC
GGRSSARETIARCVAGAIAKLALKQYGIQIQAYTSQVGPIKLAGSYQDYDLSLTEKSDVR
CCCHHHHHHHHHHHHHHHHHHHHHHHCEEEEEECCCCCCEEEECCCCCCEEEECCCCCCC
CPDPKTASEMETLIAEVKSKGDTIGGVITCVAKGVPVGLGEPVFGKLHAALGHAMLTINA
CCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHEEEEEE
VKGFEYGDGFNAAFFRGSERNDRFFNDNGHINTRTNNSGGIQGGISNGQDIYFRVAFKSV
ECCCCCCCCCCEEEEECCCCCCCEECCCCEEEEECCCCCCCCCCCCCCCEEEEEEHHHHH
ATILMEQETVNMEGEDTILKARGRHDPCVLPRAVPIVESMTAMTLLDYLLIQKTRENF
HHHHHHHHHCCCCCCCCEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNTFGNIYRLTSFGESHGPGIGGVIDGCPAGIELDTAFIQQELNRRKPGQSRITTPRKED
CCCCCCEEEEECCCCCCCCCCCCHHCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCC
DEVQFLSGIYEGKTTGTPIGFIIWNKNQHSSDYDNMKTVYRPSHADYTYQTKYGIRDPRG
CHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCCCCCHHHCCCCCCCEEEEEECCCCCCCC
GGRSSARETIARCVAGAIAKLALKQYGIQIQAYTSQVGPIKLAGSYQDYDLSLTEKSDVR
CCCHHHHHHHHHHHHHHHHHHHHHHHCEEEEEECCCCCCEEEECCCCCCEEEECCCCCCC
CPDPKTASEMETLIAEVKSKGDTIGGVITCVAKGVPVGLGEPVFGKLHAALGHAMLTINA
CCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHEEEEEE
VKGFEYGDGFNAAFFRGSERNDRFFNDNGHINTRTNNSGGIQGGISNGQDIYFRVAFKSV
ECCCCCCCCCCEEEEECCCCCCCEECCCCEEEEECCCCCCCCCCCCCCCEEEEEEHHHHH
ATILMEQETVNMEGEDTILKARGRHDPCVLPRAVPIVESMTAMTLLDYLLIQKTRENF
HHHHHHHHHCCCCCCCCEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA