Click here to switch to the map view.

The map label for this gene is slyD [H]

Identifier: 150008691

GI number: 150008691

Start: 2464732

End: 2465307

Strand: Direct

Name: slyD [H]

Synonym: BDI_2081

Alternate gene names: 150008691

Gene position: 2464732-2465307 (Clockwise)

Preceding gene: 150008690

Following gene: 150008692

Centisome position: 51.23

GC content: 50.87

Gene sequence:

>576_bases
ATGAAAATTACAGCAAACAAATACGTTGCGGTTACATACGACCTGAACGTTGGCGAAGGTGAAGAACGTGAGTTAATGGA
AAAAGCGACGGTCGAGGCTCCTTTGAAATTCATCTACGGAACAGGCATGATGCTTCCGGCATTCGAGAAAGCCTTGAACG
GGCTGGAAGTAGGTGGCACGTTCAACTTCTCCATCGAGCCAGCCGAGGCTTATGGCGAATATAACGAGGAGCACGTATTG
GATCTTCCGAAGAATATCTTCGAGGTAGACGGTAAATTCGACGCCGAGATGATCAAGGAAGGTAATACCGTACCGATGAT
GGATTCTAATGGCAACCGTATGAACGGCTCCGTATTGGAAGTGAAGGATGATATCGTGGTAATGGACTTCAACCATCCGT
TGGCTGGCGAGACTTTGCATTTCAGCGGCGAGGTAATCGACGTACACGAACCGACAGCGGAAGAGATCGCTGCCTTCTCC
GCTCCCGCAGGTGGATGCAGTTGCGGTTGCGACGATTGCGGTAGCGATTGTGGCGATAACCACGAGGGTGGCTGCGGTTG
TGGTGGATGCCACTAA

Upstream 100 bases:

>100_bases
TGTTTTAGATAAAGCGATGAACGCTCTTAAAAAGGCGGTGGATAAGAAATAAAATCGTATCTTTGCGAGCATTTCTATAC
ATATTTAAAATACAAGACAA

Downstream 100 bases:

>100_bases
ATAAAGGGAAATTGAGAATTGAAAATTGAAAATTAGGAGAAGTGCCTAATCATCGGCTTTTGATTCTCAATTTTCAGTTT
TCAATTTTCAATTAGACAAA

Product: peptidyl-prolyl cis-trans isomerase SlyD

Products: NA

Alternate protein names: PPIase; Metallochaperone slyD [H]

Number of amino acids: Translated: 191; Mature: 191

Protein sequence:

>191_residues
MKITANKYVAVTYDLNVGEGEERELMEKATVEAPLKFIYGTGMMLPAFEKALNGLEVGGTFNFSIEPAEAYGEYNEEHVL
DLPKNIFEVDGKFDAEMIKEGNTVPMMDSNGNRMNGSVLEVKDDIVVMDFNHPLAGETLHFSGEVIDVHEPTAEEIAAFS
APAGGCSCGCDDCGSDCGDNHEGGCGCGGCH

Sequences:

>Translated_191_residues
MKITANKYVAVTYDLNVGEGEERELMEKATVEAPLKFIYGTGMMLPAFEKALNGLEVGGTFNFSIEPAEAYGEYNEEHVL
DLPKNIFEVDGKFDAEMIKEGNTVPMMDSNGNRMNGSVLEVKDDIVVMDFNHPLAGETLHFSGEVIDVHEPTAEEIAAFS
APAGGCSCGCDDCGSDCGDNHEGGCGCGGCH
>Mature_191_residues
MKITANKYVAVTYDLNVGEGEERELMEKATVEAPLKFIYGTGMMLPAFEKALNGLEVGGTFNFSIEPAEAYGEYNEEHVL
DLPKNIFEVDGKFDAEMIKEGNTVPMMDSNGNRMNGSVLEVKDDIVVMDFNHPLAGETLHFSGEVIDVHEPTAEEIAAFS
APAGGCSCGCDDCGSDCGDNHEGGCGCGGCH

Specific function: Also involved in hydrogenase metallocenter assembly, probably by participating in the nickel insertion step. This function in hydrogenase biosynthesis requires chaperone activity and the presence of the metal-binding domain, but not PPIase activity [H]

COG id: COG1047

COG function: function code O; FKBP-type peptidyl-prolyl cis-trans isomerases 2

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PPIase FKBP-type domain [H]

Homologues:

Organism=Escherichia coli, GI1789748, Length=163, Percent_Identity=33.7423312883436, Blast_Score=85, Evalue=4e-18,
Organism=Escherichia coli, GI1786211, Length=147, Percent_Identity=29.2517006802721, Blast_Score=63, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001179 [H]

Pfam domain/function: PF00254 FKBP_C [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 20457; Mature: 20457

Theoretical pI: Translated: 3.99; Mature: 3.99

Prosite motif: PS00022 EGF_1 ; PS50059 FKBP_PPIASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.2 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
8.9 %Cys+Met (Translated Protein)
4.2 %Cys     (Mature Protein)
4.7 %Met     (Mature Protein)
8.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKITANKYVAVTYDLNVGEGEERELMEKATVEAPLKFIYGTGMMLPAFEKALNGLEVGGT
CEEECCEEEEEEEEECCCCCHHHHHHHHHHHHHCHHEEECCCCCHHHHHHHHCCEECCCE
FNFSIEPAEAYGEYNEEHVLDLPKNIFEVDGKFDAEMIKEGNTVPMMDSNGNRMNGSVLE
EEEEECHHHHHCCCCCCHHHHCCCHHEECCCCCCHHHHHCCCEEEEECCCCCCCCCCEEE
VKDDIVVMDFNHPLAGETLHFSGEVIDVHEPTAEEIAAFSAPAGGCSCGCDDCGSDCGDN
EECCEEEEECCCCCCCCEEEECCCEEECCCCCHHHHHHHCCCCCCCCCCCHHHCCCCCCC
HEGGCGCGGCH
CCCCCCCCCCC
>Mature Secondary Structure
MKITANKYVAVTYDLNVGEGEERELMEKATVEAPLKFIYGTGMMLPAFEKALNGLEVGGT
CEEECCEEEEEEEEECCCCCHHHHHHHHHHHHHCHHEEECCCCCHHHHHHHHCCEECCCE
FNFSIEPAEAYGEYNEEHVLDLPKNIFEVDGKFDAEMIKEGNTVPMMDSNGNRMNGSVLE
EEEEECHHHHHCCCCCCHHHHCCCHHEECCCCCCHHHHHCCCEEEEECCCCCCCCCCEEE
VKDDIVVMDFNHPLAGETLHFSGEVIDVHEPTAEEIAAFSAPAGGCSCGCDDCGSDCGDN
EECCEEEEECCCCCCCCEEEECCCEEECCCCCHHHHHHHCCCCCCCCCCCHHHCCCCCCC
HEGGCGCGGCH
CCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11248100 [H]