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The map label for this gene is corC [H]

Identifier: 150008606

GI number: 150008606

Start: 2355022

End: 2356374

Strand: Reverse

Name: corC [H]

Synonym: BDI_1992

Alternate gene names: 150008606

Gene position: 2356374-2355022 (Counterclockwise)

Preceding gene: 150008607

Following gene: 150008605

Centisome position: 48.98

GC content: 43.31

Gene sequence:

>1353_bases
TTGGACTCGGACTATTATTTATGGGGCTTATTTGAAAACGTAACGGTGCAGGCGCTGACAGCGGGTCCTGTGATCGCATT
AAGCCTCGCTTTTTTACTGCTGTTTGTTTCCGGCTTCGTGTCGGCCTCTGAAGTGGCATTCTTTTCTCTAACCCCGGGTG
ACCTAAATGAGATCGGGGAAGAGAATCGCCCGGCAGATCCTGTTATCAAACGTCTCCTTGAACGTTCGGAGTATCTATTG
GCATCTATATTGATCGCTAATAATTTTGTAAATGTGGCGGTCGTTATGCTGTGTACCTATGCGATTAACGCTTGGATTAA
TTTCTCGGCCGCTCCTCTTCTAGGCTTTGTGCTTGAGACGATTCTCTTGACTTTCTTGCTTTTACTTTTTGGGGAGATCA
TGCCTAAGATTTACGCACAGAAGAATTCTTTGCGTTTTGTTCGTTTTTCAGCCTCCGTATTAAGTGGTTTGGAACGCTTC
TGCCGCCCATTCTCGAAAATCTTGGTTAATTCCACATCGGTCATCAATAAAGCGTTAGCGAAAAAGAAATATGATATCTC
TGTAGATGAGCTTTCTAAAGCGTTAGAGCTAACCTCTACCGAGATCCCGGAGGAGAAGGAGATGCTGGCGGAGATTATCA
AGTTTTATAATAAGACCGCTGATGAGATCATGACTCCTCGTCTGGATATGGAAGATATCGAGATCAAGATCAGTTTCCGT
GAGGTGGTTGATTTTATTATCAAATCCGGCTATTCGCGTATTCCGGTATATTCCGAGACTGAGGATAATATAAAAGGTAT
CTTATATATCAAGGACTTATTGCCCTATATTGACAAGCCCGATACATTCCGTTGGCAGAGCTTGATCCGACCGGCCTATT
TCGTGCCGGAAACCAAGAAGATCGATGATTTGCTGGAAGAGTTCCGTACCAATAAAATTCATATGGCGATCGTGGTCGAT
GAGTTTGGCGGTACCTCCGGTATCGTGACGATGGAAGATATCCTAGAGGAAATTGTTGGAGAGATCTCCGATGAGTATGA
TGAGGATGAGCAACAATTCATCCGTTTAGCAGACGGTAGCTTGATCTTTGAGGCAAAGATATTATTGACGGATTTCTTCC
GGGTTATCGATGCCGATCCCTCAGATTTTGGTAAATTGACGGAAGAAGTGGAAACTTTGGCCGGTCTTTTGTTGGAGATA
AAAGGGGATTTTCCACGCCGTAGGGAGATTATAGATTTTAAGGAATATCGTTTCCAAGTGCTGGAAGTGGATAACAGGAG
GATATTAAAGGTTAAATTTAACCGTATCCTTGAAGATACAGGGAATGATGAGAATGGGAAAGATACGAAGTAA

Upstream 100 bases:

>100_bases
GCTTATCAACAGCCAGCCGCCTCGCAGCCTAGCGCATTCTCAGAATCCAGTGACGCGGATGATCTCCCGTTCTGATATTG
TTTAACTAATACTGTTTCCC

Downstream 100 bases:

>100_bases
ATGTTTATGAAATGGATAGCTGCTGTCATAGGAGGTTCTCTGTTTTTAGGGATATGCTGTATTTCGTGTGTGGAATATAC
GCCGAAGCCACGGGGCTATG

Product: hemolysin-like protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 450; Mature: 450

Protein sequence:

>450_residues
MDSDYYLWGLFENVTVQALTAGPVIALSLAFLLLFVSGFVSASEVAFFSLTPGDLNEIGEENRPADPVIKRLLERSEYLL
ASILIANNFVNVAVVMLCTYAINAWINFSAAPLLGFVLETILLTFLLLLFGEIMPKIYAQKNSLRFVRFSASVLSGLERF
CRPFSKILVNSTSVINKALAKKKYDISVDELSKALELTSTEIPEEKEMLAEIIKFYNKTADEIMTPRLDMEDIEIKISFR
EVVDFIIKSGYSRIPVYSETEDNIKGILYIKDLLPYIDKPDTFRWQSLIRPAYFVPETKKIDDLLEEFRTNKIHMAIVVD
EFGGTSGIVTMEDILEEIVGEISDEYDEDEQQFIRLADGSLIFEAKILLTDFFRVIDADPSDFGKLTEEVETLAGLLLEI
KGDFPRRREIIDFKEYRFQVLEVDNRRILKVKFNRILEDTGNDENGKDTK

Sequences:

>Translated_450_residues
MDSDYYLWGLFENVTVQALTAGPVIALSLAFLLLFVSGFVSASEVAFFSLTPGDLNEIGEENRPADPVIKRLLERSEYLL
ASILIANNFVNVAVVMLCTYAINAWINFSAAPLLGFVLETILLTFLLLLFGEIMPKIYAQKNSLRFVRFSASVLSGLERF
CRPFSKILVNSTSVINKALAKKKYDISVDELSKALELTSTEIPEEKEMLAEIIKFYNKTADEIMTPRLDMEDIEIKISFR
EVVDFIIKSGYSRIPVYSETEDNIKGILYIKDLLPYIDKPDTFRWQSLIRPAYFVPETKKIDDLLEEFRTNKIHMAIVVD
EFGGTSGIVTMEDILEEIVGEISDEYDEDEQQFIRLADGSLIFEAKILLTDFFRVIDADPSDFGKLTEEVETLAGLLLEI
KGDFPRRREIIDFKEYRFQVLEVDNRRILKVKFNRILEDTGNDENGKDTK
>Mature_450_residues
MDSDYYLWGLFENVTVQALTAGPVIALSLAFLLLFVSGFVSASEVAFFSLTPGDLNEIGEENRPADPVIKRLLERSEYLL
ASILIANNFVNVAVVMLCTYAINAWINFSAAPLLGFVLETILLTFLLLLFGEIMPKIYAQKNSLRFVRFSASVLSGLERF
CRPFSKILVNSTSVINKALAKKKYDISVDELSKALELTSTEIPEEKEMLAEIIKFYNKTADEIMTPRLDMEDIEIKISFR
EVVDFIIKSGYSRIPVYSETEDNIKGILYIKDLLPYIDKPDTFRWQSLIRPAYFVPETKKIDDLLEEFRTNKIHMAIVVD
EFGGTSGIVTMEDILEEIVGEISDEYDEDEQQFIRLADGSLIFEAKILLTDFFRVIDADPSDFGKLTEEVETLAGLLLEI
KGDFPRRREIIDFKEYRFQVLEVDNRRILKVKFNRILEDTGNDENGKDTK

Specific function: Plays a role in the transport of magnesium and cobalt ions [H]

COG id: COG1253

COG function: function code R; Hemolysins and related proteins containing CBS domains

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 CBS domains [H]

Homologues:

Organism=Homo sapiens, GI310128564, Length=402, Percent_Identity=24.3781094527363, Blast_Score=130, Evalue=3e-30,
Organism=Homo sapiens, GI94681046, Length=346, Percent_Identity=29.1907514450867, Blast_Score=102, Evalue=5e-22,
Organism=Homo sapiens, GI40068053, Length=351, Percent_Identity=27.6353276353276, Blast_Score=100, Evalue=3e-21,
Organism=Homo sapiens, GI40068055, Length=351, Percent_Identity=27.6353276353276, Blast_Score=100, Evalue=3e-21,
Organism=Homo sapiens, GI40068049, Length=164, Percent_Identity=35.3658536585366, Blast_Score=81, Evalue=2e-15,
Organism=Homo sapiens, GI40068051, Length=310, Percent_Identity=25.4838709677419, Blast_Score=77, Evalue=5e-14,
Organism=Homo sapiens, GI157412263, Length=295, Percent_Identity=24.0677966101695, Blast_Score=67, Evalue=4e-11,
Organism=Escherichia coli, GI1786879, Length=229, Percent_Identity=39.7379912663755, Blast_Score=153, Evalue=3e-38,
Organism=Escherichia coli, GI145693175, Length=406, Percent_Identity=24.384236453202, Blast_Score=127, Evalue=1e-30,
Organism=Escherichia coli, GI87082033, Length=379, Percent_Identity=26.9129287598945, Blast_Score=123, Evalue=3e-29,
Organism=Escherichia coli, GI1790664, Length=335, Percent_Identity=25.0746268656716, Blast_Score=99, Evalue=4e-22,
Organism=Escherichia coli, GI1788119, Length=242, Percent_Identity=27.2727272727273, Blast_Score=82, Evalue=5e-17,
Organism=Caenorhabditis elegans, GI71980512, Length=373, Percent_Identity=27.6139410187668, Blast_Score=93, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI17539402, Length=343, Percent_Identity=26.530612244898, Blast_Score=69, Evalue=7e-12,
Organism=Saccharomyces cerevisiae, GI6324512, Length=257, Percent_Identity=27.6264591439689, Blast_Score=66, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016169
- InterPro:   IPR000644
- InterPro:   IPR005170 [H]

Pfam domain/function: PF00571 CBS; PF03471 CorC_HlyC [H]

EC number: NA

Molecular weight: Translated: 51369; Mature: 51369

Theoretical pI: Translated: 4.33; Mature: 4.33

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDSDYYLWGLFENVTVQALTAGPVIALSLAFLLLFVSGFVSASEVAFFSLTPGDLNEIGE
CCCCEEEEEECCCCEEEEECCCHHHHHHHHHHHHHHHHCCCHHHEEEEEECCCCHHHCCC
ENRPADPVIKRLLERSEYLLASILIANNFVNVAVVMLCTYAINAWINFSAAPLLGFVLET
CCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
ILLTFLLLLFGEIMPKIYAQKNSLRFVRFSASVLSGLERFCRPFSKILVNSTSVINKALA
HHHHHHHHHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHH
KKKYDISVDELSKALELTSTEIPEEKEMLAEIIKFYNKTADEIMTPRLDMEDIEIKISFR
HCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCHHHHCCCCCCCCCEEEEEEHH
EVVDFIIKSGYSRIPVYSETEDNIKGILYIKDLLPYIDKPDTFRWQSLIRPAYFVPETKK
HHHHHHHHCCCCCCCCCCCCCCCCCCEEEHHHHHHHCCCCCCHHHHHHCCCHHCCCCCHH
IDDLLEEFRTNKIHMAIVVDEFGGTSGIVTMEDILEEIVGEISDEYDEDEQQFIRLADGS
HHHHHHHHCCCCEEEEEEEECCCCCCCCEEHHHHHHHHHHHHHHCCCCHHHHHHHHHCCC
LIFEAKILLTDFFRVIDADPSDFGKLTEEVETLAGLLLEIKGDFPRRREIIDFKEYRFQV
EEEHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHEEE
LEVDNRRILKVKFNRILEDTGNDENGKDTK
EEECCCEEEEEHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure
MDSDYYLWGLFENVTVQALTAGPVIALSLAFLLLFVSGFVSASEVAFFSLTPGDLNEIGE
CCCCEEEEEECCCCEEEEECCCHHHHHHHHHHHHHHHHCCCHHHEEEEEECCCCHHHCCC
ENRPADPVIKRLLERSEYLLASILIANNFVNVAVVMLCTYAINAWINFSAAPLLGFVLET
CCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
ILLTFLLLLFGEIMPKIYAQKNSLRFVRFSASVLSGLERFCRPFSKILVNSTSVINKALA
HHHHHHHHHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHH
KKKYDISVDELSKALELTSTEIPEEKEMLAEIIKFYNKTADEIMTPRLDMEDIEIKISFR
HCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCHHHHCCCCCCCCCEEEEEEHH
EVVDFIIKSGYSRIPVYSETEDNIKGILYIKDLLPYIDKPDTFRWQSLIRPAYFVPETKK
HHHHHHHHCCCCCCCCCCCCCCCCCCEEEHHHHHHHCCCCCCHHHHHHCCCHHCCCCCHH
IDDLLEEFRTNKIHMAIVVDEFGGTSGIVTMEDILEEIVGEISDEYDEDEQQFIRLADGS
HHHHHHHHCCCCEEEEEEEECCCCCCCCEEHHHHHHHHHHHHHHCCCCHHHHHHHHHCCC
LIFEAKILLTDFFRVIDADPSDFGKLTEEVETLAGLLLEIKGDFPRRREIIDFKEYRFQV
EEEHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHEEE
LEVDNRRILKVKFNRILEDTGNDENGKDTK
EEECCCEEEEEHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12522265 [H]