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The map label for this gene is aroE [H]

Identifier: 150008603

GI number: 150008603

Start: 2352962

End: 2353705

Strand: Direct

Name: aroE [H]

Synonym: BDI_1989

Alternate gene names: 150008603

Gene position: 2352962-2353705 (Clockwise)

Preceding gene: 150008602

Following gene: 150008609

Centisome position: 48.9

GC content: 43.01

Gene sequence:

>744_bases
ATGCAGAAATATGGCTTACTGGGATATCCCCTCGGACATTCGTTTTCTAAAACGTATTTCAACCAGAAGTTTGAGGCGGA
GAAGATCGACGCTGAGTACTTGAATTTCGAGATTCCCTCTATCAAGGAGATTAAGAACGTAATCAAAGAAAACCCTGAAC
TTAACGGTTTAAACGTGACCATTCCTTATAAGGAACAAGTAATCCCATATTTAGACGATTTGGATGACGATGCCCGTCAG
ATCGGAGCGGTAAATGTCATCAAGTTCACAAAAGGTCTTTTCGGCAAACTTAAACTGAAAGGATATAACTCGGATATTAT
CGGATTCAAGCAATCGATTGATCCTTTATTGAAAGAAACGCACCGGAAAGCGTTGATCCTTGGTACGGGAGGGGCGTCAA
AGGCAGTCTTCCATGGACTGAAACAGCTAGGTGTTGGTGCCACGCTGGTTTCTCGCAAACCGAAAGAATTTTGTATCACG
TACGATGAGATTACTCCGAAGACCATGGAGCAATATACGGTGATCGTGAATACGACTCCCTTAGGCATGTTCCCGAATAT
AGACTCATGTCCGGATATCCCGTACGATTTACTTACGCCGAATCATCTATTGTATGATTTACTTTACAATCCGGATGAGA
CCCTTTTCATGAAGAAAGGAAAAGAAAAAGGCGCCGTCGTGAAAAATGGTCTGGAAATGCTTCTATTACAGGCTTTCGCC
GCTTGGGAGATCTGGCAGAAATAG

Upstream 100 bases:

>100_bases
TACTCACCCGCCAAGGCTTCAAGCAGGCCCGTGTACGGACCTTTACCTTCGGGATCTGTTCATTATATACAGGATCTAAA
GAATAAACAATAAAAAGGTT

Downstream 100 bases:

>100_bases
ATCGAACGATATCTTTCCAACCACATGATTTGATGAAGCTAGCTTCGTGAGCCAATGAAGTTAGCTTCGTTAGTCAATGA
AGTTAACTTCACAAGCGTAT

Product: putative shikimate 5-dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 247; Mature: 247

Protein sequence:

>247_residues
MQKYGLLGYPLGHSFSKTYFNQKFEAEKIDAEYLNFEIPSIKEIKNVIKENPELNGLNVTIPYKEQVIPYLDDLDDDARQ
IGAVNVIKFTKGLFGKLKLKGYNSDIIGFKQSIDPLLKETHRKALILGTGGASKAVFHGLKQLGVGATLVSRKPKEFCIT
YDEITPKTMEQYTVIVNTTPLGMFPNIDSCPDIPYDLLTPNHLLYDLLYNPDETLFMKKGKEKGAVVKNGLEMLLLQAFA
AWEIWQK

Sequences:

>Translated_247_residues
MQKYGLLGYPLGHSFSKTYFNQKFEAEKIDAEYLNFEIPSIKEIKNVIKENPELNGLNVTIPYKEQVIPYLDDLDDDARQ
IGAVNVIKFTKGLFGKLKLKGYNSDIIGFKQSIDPLLKETHRKALILGTGGASKAVFHGLKQLGVGATLVSRKPKEFCIT
YDEITPKTMEQYTVIVNTTPLGMFPNIDSCPDIPYDLLTPNHLLYDLLYNPDETLFMKKGKEKGAVVKNGLEMLLLQAFA
AWEIWQK
>Mature_247_residues
MQKYGLLGYPLGHSFSKTYFNQKFEAEKIDAEYLNFEIPSIKEIKNVIKENPELNGLNVTIPYKEQVIPYLDDLDDDARQ
IGAVNVIKFTKGLFGKLKLKGYNSDIIGFKQSIDPLLKETHRKALILGTGGASKAVFHGLKQLGVGATLVSRKPKEFCIT
YDEITPKTMEQYTVIVNTTPLGMFPNIDSCPDIPYDLLTPNHLLYDLLYNPDETLFMKKGKEKGAVVKNGLEMLLLQAFA
AWEIWQK

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; fourth step. [C]

COG id: COG0169

COG function: function code E; Shikimate 5-dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the shikimate dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1789675, Length=268, Percent_Identity=27.9850746268657, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI1787983, Length=275, Percent_Identity=26.5454545454545, Blast_Score=82, Evalue=4e-17,
Organism=Saccharomyces cerevisiae, GI6320332, Length=265, Percent_Identity=28.3018867924528, Blast_Score=77, Evalue=3e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016040
- InterPro:   IPR011342
- InterPro:   IPR013708
- InterPro:   IPR022893
- InterPro:   IPR006151 [H]

Pfam domain/function: PF01488 Shikimate_DH; PF08501 Shikimate_dh_N [H]

EC number: =1.1.1.25 [H]

Molecular weight: Translated: 27912; Mature: 27912

Theoretical pI: Translated: 7.55; Mature: 7.55

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQKYGLLGYPLGHSFSKTYFNQKFEAEKIDAEYLNFEIPSIKEIKNVIKENPELNGLNVT
CCCCCCCCCCCCCCHHHHHHCCCCCHHHCCHHHEEECCCCHHHHHHHHHCCCCCCCEEEE
IPYKEQVIPYLDDLDDDARQIGAVNVIKFTKGLFGKLKLKGYNSDIIGFKQSIDPLLKET
ECCHHHCCCHHCCCCHHHHHHCCHHHHHHHHCCCEEEEEECCCCCCCCCHHHHHHHHHHH
HRKALILGTGGASKAVFHGLKQLGVGATLVSRKPKEFCITYDEITPKTMEQYTVIVNTTP
CCCEEEEECCCCHHHHHHHHHHHCCCHHHHCCCCHHHEEEECCCCCCCHHEEEEEEECCC
LGMFPNIDSCPDIPYDLLTPNHLLYDLLYNPDETLFMKKGKEKGAVVKNGLEMLLLQAFA
CCCCCCCCCCCCCCHHHCCCHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHH
AWEIWQK
HHHHHCC
>Mature Secondary Structure
MQKYGLLGYPLGHSFSKTYFNQKFEAEKIDAEYLNFEIPSIKEIKNVIKENPELNGLNVT
CCCCCCCCCCCCCCHHHHHHCCCCCHHHCCHHHEEECCCCHHHHHHHHHCCCCCCCEEEE
IPYKEQVIPYLDDLDDDARQIGAVNVIKFTKGLFGKLKLKGYNSDIIGFKQSIDPLLKET
ECCHHHCCCHHCCCCHHHHHHCCHHHHHHHHCCCEEEEEECCCCCCCCCHHHHHHHHHHH
HRKALILGTGGASKAVFHGLKQLGVGATLVSRKPKEFCITYDEITPKTMEQYTVIVNTTP
CCCEEEEECCCCHHHHHHHHHHHCCCHHHHCCCCHHHEEEECCCCCCCHHEEEEEEECCC
LGMFPNIDSCPDIPYDLLTPNHLLYDLLYNPDETLFMKKGKEKGAVVKNGLEMLLLQAFA
CCCCCCCCCCCCCCHHHCCCHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHH
AWEIWQK
HHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA