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The map label for this gene is ubiE [H]

Identifier: 150008602

GI number: 150008602

Start: 2352204

End: 2352947

Strand: Direct

Name: ubiE [H]

Synonym: BDI_1988

Alternate gene names: 150008602

Gene position: 2352204-2352947 (Clockwise)

Preceding gene: 150008601

Following gene: 150008603

Centisome position: 48.89

GC content: 47.18

Gene sequence:

>744_bases
ATGACACAGTATGGTTCAGAGACAATACTTCCTTATAACAAAGAGGAACAAAAGGGCACGCAAGTCAAACGTATGTTCGA
CTCGATAGCCGAAACGTATGATCAACTCAACCATACTCTCTCATTTGGTATCGACAAGATATGGCGCAGGAAAGGGATCG
CTTTCCTGCGTCCTTTCTCTCCTAAAACGATACTGGATATCGCTACCGGTACCGGAGACTTGGCTATCTCCATGTACAAA
AAGCTGCGACCCGACCATATCGTCGGTGCCGACATCTCGTTAGGCATGATGGAAGTGGGACGGAAAAAAGTAGCTGCCGC
CGGTTATTCGGAGCATATATCCTTCGAGCAACAGGACTGTACGGCCTTGACCTACGAGGAAAACTCGTTCGATGCCGTAA
CCGCCGCTTTCGGGGTTCGTAATTTTGAGAACATAGAGCAAGGTATCTCAGAGATGTACCGGGTGCTGAAACCCGGTGGA
CATATCATGATCTTGGAACTTTCCACACCGGAACATTTTCCCATGAGACAACTCTACCAGATCTATTCAAAGACCGTCAT
CCCCTTTATCGGACGTCTACTCTCTAAAGAAAAAGTCGCGTATAATTATTTGCCGGCTTCCATCAAGGTAGTTCCTCAGG
GAAAGGTCATGACGGATTTACTCACCCGCCAAGGCTTCAAGCAGGCCCGTGTACGGACCTTTACCTTCGGGATCTGTTCA
TTATATACAGGATCTAAAGAATAA

Upstream 100 bases:

>100_bases
ATCACAGGGGAGACTTTCGTAAAAGGCGAGACTGATAACTTGCTGAACCGCATCGAGAAAAACGTTACTGAATATTTACA
GAATAAATAAGATACCGCAC

Downstream 100 bases:

>100_bases
ACAATAAAAAGGTTATGCAGAAATATGGCTTACTGGGATATCCCCTCGGACATTCGTTTTCTAAAACGTATTTCAACCAG
AAGTTTGAGGCGGAGAAGAT

Product: ubiquinone/menaquinone biosynthesis methyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 247; Mature: 246

Protein sequence:

>247_residues
MTQYGSETILPYNKEEQKGTQVKRMFDSIAETYDQLNHTLSFGIDKIWRRKGIAFLRPFSPKTILDIATGTGDLAISMYK
KLRPDHIVGADISLGMMEVGRKKVAAAGYSEHISFEQQDCTALTYEENSFDAVTAAFGVRNFENIEQGISEMYRVLKPGG
HIMILELSTPEHFPMRQLYQIYSKTVIPFIGRLLSKEKVAYNYLPASIKVVPQGKVMTDLLTRQGFKQARVRTFTFGICS
LYTGSKE

Sequences:

>Translated_247_residues
MTQYGSETILPYNKEEQKGTQVKRMFDSIAETYDQLNHTLSFGIDKIWRRKGIAFLRPFSPKTILDIATGTGDLAISMYK
KLRPDHIVGADISLGMMEVGRKKVAAAGYSEHISFEQQDCTALTYEENSFDAVTAAFGVRNFENIEQGISEMYRVLKPGG
HIMILELSTPEHFPMRQLYQIYSKTVIPFIGRLLSKEKVAYNYLPASIKVVPQGKVMTDLLTRQGFKQARVRTFTFGICS
LYTGSKE
>Mature_246_residues
TQYGSETILPYNKEEQKGTQVKRMFDSIAETYDQLNHTLSFGIDKIWRRKGIAFLRPFSPKTILDIATGTGDLAISMYKK
LRPDHIVGADISLGMMEVGRKKVAAAGYSEHISFEQQDCTALTYEENSFDAVTAAFGVRNFENIEQGISEMYRVLKPGGH
IMILELSTPEHFPMRQLYQIYSKTVIPFIGRLLSKEKVAYNYLPASIKVVPQGKVMTDLLTRQGFKQARVRTFTFGICSL
YTGSKE

Specific function: Methyltransferase required for the conversion of dimethylmenaquinone (DMKH2) to menaquinone (MKH2) [H]

COG id: COG2226

COG function: function code H; Methylase involved in ubiquinone/menaquinone biosynthesis

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. UbiE family [H]

Homologues:

Organism=Homo sapiens, GI116063536, Length=279, Percent_Identity=30.1075268817204, Blast_Score=154, Evalue=1e-37,
Organism=Escherichia coli, GI48994983, Length=246, Percent_Identity=34.1463414634146, Blast_Score=161, Evalue=4e-41,
Organism=Caenorhabditis elegans, GI17557039, Length=235, Percent_Identity=31.9148936170213, Blast_Score=140, Evalue=5e-34,
Organism=Saccharomyces cerevisiae, GI6323526, Length=266, Percent_Identity=31.9548872180451, Blast_Score=128, Evalue=1e-30,
Organism=Drosophila melanogaster, GI24641702, Length=259, Percent_Identity=32.8185328185328, Blast_Score=155, Evalue=3e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004033 [H]

Pfam domain/function: PF01209 Ubie_methyltran [H]

EC number: 2.1.1.-

Molecular weight: Translated: 27962; Mature: 27830

Theoretical pI: Translated: 9.34; Mature: 9.34

Prosite motif: PS01183 UBIE_1 ; PS01184 UBIE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQYGSETILPYNKEEQKGTQVKRMFDSIAETYDQLNHTLSFGIDKIWRRKGIAFLRPFS
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCC
PKTILDIATGTGDLAISMYKKLRPDHIVGADISLGMMEVGRKKVAAAGYSEHISFEQQDC
CCEEEEEECCCCHHHHHHHHHCCCCCEECCCCHHHHHHHHHHHHHHCCHHHHCCCCCCCC
TALTYEENSFDAVTAAFGVRNFENIEQGISEMYRVLKPGGHIMILELSTPEHFPMRQLYQ
EEEEECCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCHHHHHH
IYSKTVIPFIGRLLSKEKVAYNYLPASIKVVPQGKVMTDLLTRQGFKQARVRTFTFGICS
HHHHHHHHHHHHHHHHHHHHHEECCCEEEEEECCHHHHHHHHHCCHHHHHHHHHHHHHHH
LYTGSKE
HCCCCCC
>Mature Secondary Structure 
TQYGSETILPYNKEEQKGTQVKRMFDSIAETYDQLNHTLSFGIDKIWRRKGIAFLRPFS
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCC
PKTILDIATGTGDLAISMYKKLRPDHIVGADISLGMMEVGRKKVAAAGYSEHISFEQQDC
CCEEEEEECCCCHHHHHHHHHCCCCCEECCCCHHHHHHHHHHHHHHCCHHHHCCCCCCCC
TALTYEENSFDAVTAAFGVRNFENIEQGISEMYRVLKPGGHIMILELSTPEHFPMRQLYQ
EEEEECCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCHHHHHH
IYSKTVIPFIGRLLSKEKVAYNYLPASIKVVPQGKVMTDLLTRQGFKQARVRTFTFGICS
HHHHHHHHHHHHHHHHHHHHHEECCCEEEEEECCHHHHHHHHHCCHHHHHHHHHHHHHHH
LYTGSKE
HCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Transferring one-carbon groups; Methyltransferases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12663928 [H]