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The map label for this gene is purC [H]

Identifier: 150008601

GI number: 150008601

Start: 2351243

End: 2352193

Strand: Direct

Name: purC [H]

Synonym: BDI_1987

Alternate gene names: 150008601

Gene position: 2351243-2352193 (Clockwise)

Preceding gene: 150008600

Following gene: 150008602

Centisome position: 48.87

GC content: 46.9

Gene sequence:

>951_bases
ATGAAGAAGGCATTAGTTAAAACAGACTTCAATTTCCCGCGACAAAAGAGCGTATACCATGGGAAAGTACGCGACGTGTA
CAACATCAATGACGAGGTATTGGTAATGGTCGCTACAGACCGTATTTCCGCTTTCGATGTTATCTTGCCGGAAGGTATTC
CTTACAAGGGACAAATGTTAAACCAGATCGCCGCCAAGTTCCTTGACGCTACGACTGATATTTGTCCGAACTGGAAAATG
GCTACTCCGGACCCGATGGTAACGGTTGGCGTTCAATGCCAAGGTTTCCCGGTTGAGATGATCGTACGCGGTTATCTGTG
CGGAAGCGCATGGCGTGCTTATAAGAGCGGTGTACGTGAGATCTGCGGCGTGAAACTACCGGAGGGTATGCGTGAGAACC
AACGTTTCCCCGAACCCATCATCACCCCGACCACAAAGGCTGAGATCGGAGAGCATGATCAAGATATCTCTAAAGAGGAG
ATTCTCGCTAAAGGTTTGGTCTCTAAAGAGGACTACGAGGTTCTTGAGAAATATACGATGGCCTTGTTTAAACGCGGTAC
CGAGATCGCTAAGGAACGTGGCTTGATCTTGGTTGACACGAAATATGAGTTCGGTCATCGTGACGGCAAGATCTATTTGA
TCGACGAGATCCATACTCCGGATTCCTCCCGTTATTTCTACTCAGAAGGATACGAGGATCGTTTCGCCAAAGGGGAACCG
CAGAAGCAACTTTCCAAGGAGTTCGTCCGCGAATGGTTGATGGAAAATGGCTTCCAAGGTAAATCCGGACAGAAAGTTCC
TGAAATGACACCGGAGATCGTAGAAGGAATCAGCAACCGATATATCGAATTGTTCGAGCATATCACAGGGGAGACTTTCG
TAAAAGGCGAGACTGATAACTTGCTGAACCGCATCGAGAAAAACGTTACTGAATATTTACAGAATAAATAA

Upstream 100 bases:

>100_bases
TCGTAGAGGCTTATGATAAGTTCGATGATAAACGGAAGAAAGAGATCAAAGAGGCAAAAGAGAAGAAAACGAATATAGAC
AACAACTAAAAGTAAGAGTC

Downstream 100 bases:

>100_bases
GATACCGCACATGACACAGTATGGTTCAGAGACAATACTTCCTTATAACAAAGAGGAACAAAAGGGCACGCAAGTCAAAC
GTATGTTCGACTCGATAGCC

Product: phosphoribosylaminoimidazole-succinocarboxamide synthase

Products: NA

Alternate protein names: SAICAR synthetase [H]

Number of amino acids: Translated: 316; Mature: 316

Protein sequence:

>316_residues
MKKALVKTDFNFPRQKSVYHGKVRDVYNINDEVLVMVATDRISAFDVILPEGIPYKGQMLNQIAAKFLDATTDICPNWKM
ATPDPMVTVGVQCQGFPVEMIVRGYLCGSAWRAYKSGVREICGVKLPEGMRENQRFPEPIITPTTKAEIGEHDQDISKEE
ILAKGLVSKEDYEVLEKYTMALFKRGTEIAKERGLILVDTKYEFGHRDGKIYLIDEIHTPDSSRYFYSEGYEDRFAKGEP
QKQLSKEFVREWLMENGFQGKSGQKVPEMTPEIVEGISNRYIELFEHITGETFVKGETDNLLNRIEKNVTEYLQNK

Sequences:

>Translated_316_residues
MKKALVKTDFNFPRQKSVYHGKVRDVYNINDEVLVMVATDRISAFDVILPEGIPYKGQMLNQIAAKFLDATTDICPNWKM
ATPDPMVTVGVQCQGFPVEMIVRGYLCGSAWRAYKSGVREICGVKLPEGMRENQRFPEPIITPTTKAEIGEHDQDISKEE
ILAKGLVSKEDYEVLEKYTMALFKRGTEIAKERGLILVDTKYEFGHRDGKIYLIDEIHTPDSSRYFYSEGYEDRFAKGEP
QKQLSKEFVREWLMENGFQGKSGQKVPEMTPEIVEGISNRYIELFEHITGETFVKGETDNLLNRIEKNVTEYLQNK
>Mature_316_residues
MKKALVKTDFNFPRQKSVYHGKVRDVYNINDEVLVMVATDRISAFDVILPEGIPYKGQMLNQIAAKFLDATTDICPNWKM
ATPDPMVTVGVQCQGFPVEMIVRGYLCGSAWRAYKSGVREICGVKLPEGMRENQRFPEPIITPTTKAEIGEHDQDISKEE
ILAKGLVSKEDYEVLEKYTMALFKRGTEIAKERGLILVDTKYEFGHRDGKIYLIDEIHTPDSSRYFYSEGYEDRFAKGEP
QKQLSKEFVREWLMENGFQGKSGQKVPEMTPEIVEGISNRYIELFEHITGETFVKGETDNLLNRIEKNVTEYLQNK

Specific function: De novo purine biosynthesis; seventh step. [C]

COG id: COG0152

COG function: function code F; Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the SAICAR synthetase family [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6319326, Length=302, Percent_Identity=38.7417218543046, Blast_Score=193, Evalue=3e-50,

Paralogues:

None

Copy number: 1680 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 13,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013816
- InterPro:   IPR001636
- InterPro:   IPR018236 [H]

Pfam domain/function: PF01259 SAICAR_synt [H]

EC number: =6.3.2.6 [H]

Molecular weight: Translated: 36248; Mature: 36248

Theoretical pI: Translated: 5.35; Mature: 5.35

Prosite motif: PS01058 SAICAR_SYNTHETASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKALVKTDFNFPRQKSVYHGKVRDVYNINDEVLVMVATDRISAFDVILPEGIPYKGQML
CCCCEEECCCCCCCCCCCCCCCCHHEECCCCCEEEEEECCCCCEEEEECCCCCCCHHHHH
NQIAAKFLDATTDICPNWKMATPDPMVTVGVQCQGFPVEMIVRGYLCGSAWRAYKSGVRE
HHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHH
ICGVKLPEGMRENQRFPEPIITPTTKAEIGEHDQDISKEEILAKGLVSKEDYEVLEKYTM
HHCCCCCCCCHHCCCCCCCCCCCCCHHHCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHH
ALFKRGTEIAKERGLILVDTKYEFGHRDGKIYLIDEIHTPDSSRYFYSEGYEDRFAKGEP
HHHHHHHHHHHHCCEEEEECCHHCCCCCCEEEEEEEECCCCCCCEEECCCCHHHHCCCCC
QKQLSKEFVREWLMENGFQGKSGQKVPEMTPEIVEGISNRYIELFEHITGETFVKGETDN
HHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCEEECCCHHH
LLNRIEKNVTEYLQNK
HHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKKALVKTDFNFPRQKSVYHGKVRDVYNINDEVLVMVATDRISAFDVILPEGIPYKGQML
CCCCEEECCCCCCCCCCCCCCCCHHEECCCCCEEEEEECCCCCEEEEECCCCCCCHHHHH
NQIAAKFLDATTDICPNWKMATPDPMVTVGVQCQGFPVEMIVRGYLCGSAWRAYKSGVRE
HHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHH
ICGVKLPEGMRENQRFPEPIITPTTKAEIGEHDQDISKEEILAKGLVSKEDYEVLEKYTM
HHCCCCCCCCHHCCCCCCCCCCCCCHHHCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHH
ALFKRGTEIAKERGLILVDTKYEFGHRDGKIYLIDEIHTPDSSRYFYSEGYEDRFAKGEP
HHHHHHHHHHHHCCEEEEECCHHCCCCCCEEEEEEEECCCCCCCEEECCCCHHHHCCCCC
QKQLSKEFVREWLMENGFQGKSGQKVPEMTPEIVEGISNRYIELFEHITGETFVKGETDN
HHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCEEECCCHHH
LLNRIEKNVTEYLQNK
HHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA