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The map label for this gene is hypD [H]

Identifier: 150008427

GI number: 150008427

Start: 2157592

End: 2158671

Strand: Direct

Name: hypD [H]

Synonym: BDI_1809

Alternate gene names: 150008427

Gene position: 2157592-2158671 (Clockwise)

Preceding gene: 150008426

Following gene: 150008428

Centisome position: 44.84

GC content: 52.13

Gene sequence:

>1080_bases
GTGCGTTTCGTAGACGAATATAGAAGCAACGAGAAGGTACAAACTCTTCTGGAGGCCATCCGCAAAAAGGTGACACGACC
TTGGTATATCATGGAGATTTGTGGCGGGCAAACACATGCTATCGCCCGTTATCGGCTGGAAGAGATGTTGCCGCCGGATC
TTCAACTGCTCCATGGGCCGGGTTGCCCGGTCTGTGTAACACCGGTCGAGACAATCGACTACGCCTTGAAGTTGGCGACA
CAGCCGAATGTGATCTTAGCCTCTTTCGGGGATATGATGCGAGTTCCGGGAAGTAAGGAGGATTTATTGAGCGTAAAAGC
GAGAGGAGCGGATATCCGTATGCTATATACGCCCTTGGATGCCCTATCACTGGCCGAGGAGAACCCGGATAAGGAAATCG
TATTCTTCGCAATTGGTTTTGAGACGACCGCACCTGTTCACCTCATGGCTTTGAAAGAGGCCATACGCCGAGGACTTCCG
AACTTTTCCATATTGACTTCCCTATTCACGGTACCACCCGCTATCGAGGCTATCTTATCCGATCCGGAAAGTAAAGTAGA
CGGTTTCCTGACAGCCGGACATGTCTGCGCCATCACAGGCAACAGGGCCTATCACCGATTAACCGCCCGATATAAAATCC
CGATGGTCGTCACCGGATTCGAGCCGGTAGATCTATTATATGGTATCTACCGCTGTGTCTCCCAGTTGGAAGCCGGAAGT
TATGAGGTAGAGAACGCTTACAAACGGGCCGTCCCCGAACAAGGGAATGCCGCCGCCCGCCAACTTATGGACGAGATGCT
GGAACCTTGCGACCAAGACTGGCGGGGCATCGGAATCATCCCCTCCAGCGGGCTTCAACTTCGATCCGAATATAAAAGAT
ATTCCTCCCGAATGAGATTTCAATTGTGTCCGGAAGAAAACCAGATCGCATCCGAATGTATCGCCGGACTGATTATGAGA
GGTTTGAGACACCCCTCGGACTGTCCCCATTTCGGGAAGGCCTGCCATCCCACCCATCCGCTGGGAGCCCCGATGGTCTC
CTCGGAAGGGGTTTGTGCCGCTTATTATAGATATAAATAG

Upstream 100 bases:

>100_bases
AACAGGGGGATTATATCCTCGCTCACGCAGGGATCGCTATATCTGTTGTAGATGAGAAAGAAGCGGAGGAAACACTGAAA
GACCTTAAAGAATTACAAAA

Downstream 100 bases:

>100_bases
AAAGATATGGATATACACTTGAATTGCCCGATTCCTTTTACCGACTCAGACCGTGTGCTACTGGCGCACGGAGGAGGAGG
ACGCATGACACACCAACTGA

Product: hydrogenase isoenzymes formation protein HypD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 359; Mature: 359

Protein sequence:

>359_residues
MRFVDEYRSNEKVQTLLEAIRKKVTRPWYIMEICGGQTHAIARYRLEEMLPPDLQLLHGPGCPVCVTPVETIDYALKLAT
QPNVILASFGDMMRVPGSKEDLLSVKARGADIRMLYTPLDALSLAEENPDKEIVFFAIGFETTAPVHLMALKEAIRRGLP
NFSILTSLFTVPPAIEAILSDPESKVDGFLTAGHVCAITGNRAYHRLTARYKIPMVVTGFEPVDLLYGIYRCVSQLEAGS
YEVENAYKRAVPEQGNAAARQLMDEMLEPCDQDWRGIGIIPSSGLQLRSEYKRYSSRMRFQLCPEENQIASECIAGLIMR
GLRHPSDCPHFGKACHPTHPLGAPMVSSEGVCAAYYRYK

Sequences:

>Translated_359_residues
MRFVDEYRSNEKVQTLLEAIRKKVTRPWYIMEICGGQTHAIARYRLEEMLPPDLQLLHGPGCPVCVTPVETIDYALKLAT
QPNVILASFGDMMRVPGSKEDLLSVKARGADIRMLYTPLDALSLAEENPDKEIVFFAIGFETTAPVHLMALKEAIRRGLP
NFSILTSLFTVPPAIEAILSDPESKVDGFLTAGHVCAITGNRAYHRLTARYKIPMVVTGFEPVDLLYGIYRCVSQLEAGS
YEVENAYKRAVPEQGNAAARQLMDEMLEPCDQDWRGIGIIPSSGLQLRSEYKRYSSRMRFQLCPEENQIASECIAGLIMR
GLRHPSDCPHFGKACHPTHPLGAPMVSSEGVCAAYYRYK
>Mature_359_residues
MRFVDEYRSNEKVQTLLEAIRKKVTRPWYIMEICGGQTHAIARYRLEEMLPPDLQLLHGPGCPVCVTPVETIDYALKLAT
QPNVILASFGDMMRVPGSKEDLLSVKARGADIRMLYTPLDALSLAEENPDKEIVFFAIGFETTAPVHLMALKEAIRRGLP
NFSILTSLFTVPPAIEAILSDPESKVDGFLTAGHVCAITGNRAYHRLTARYKIPMVVTGFEPVDLLYGIYRCVSQLEAGS
YEVENAYKRAVPEQGNAAARQLMDEMLEPCDQDWRGIGIIPSSGLQLRSEYKRYSSRMRFQLCPEENQIASECIAGLIMR
GLRHPSDCPHFGKACHPTHPLGAPMVSSEGVCAAYYRYK

Specific function: Required for the formation of all three hydrogenase isoenzymes [H]

COG id: COG0409

COG function: function code O; Hydrogenase maturation factor

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hypD family [H]

Homologues:

Organism=Escherichia coli, GI1789084, Length=367, Percent_Identity=43.5967302452316, Blast_Score=340, Evalue=6e-95,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002780 [H]

Pfam domain/function: PF01924 HypD [H]

EC number: NA

Molecular weight: Translated: 40088; Mature: 40088

Theoretical pI: Translated: 6.77; Mature: 6.77

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.1 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
6.7 %Cys+Met (Translated Protein)
3.1 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
6.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRFVDEYRSNEKVQTLLEAIRKKVTRPWYIMEICGGQTHAIARYRLEEMLPPDLQLLHGP
CCCHHHHCCCHHHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHHCCCCCEEEECC
GCPVCVTPVETIDYALKLATQPNVILASFGDMMRVPGSKEDLLSVKARGADIRMLYTPLD
CCCEEECCHHHHHHHHHHCCCCCEEEECCCHHHCCCCCHHHHHHHHCCCCCEEEEECCHH
ALSLAEENPDKEIVFFAIGFETTAPVHLMALKEAIRRGLPNFSILTSLFTVPPAIEAILS
HHHHHCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHCCHHHHHHHC
DPESKVDGFLTAGHVCAITGNRAYHRLTARYKIPMVVTGFEPVDLLYGIYRCVSQLEAGS
CCHHHHCCCEECCEEEEEECCCHHHEEEEEEECCEEEECCCHHHHHHHHHHHHHHHCCCC
YEVENAYKRAVPEQGNAAARQLMDEMLEPCDQDWRGIGIIPSSGLQLRSEYKRYSSRMRF
CHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHCCEE
QLCPEENQIASECIAGLIMRGLRHPSDCPHFGKACHPTHPLGAPMVSSEGVCAAYYRYK
EECCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECC
>Mature Secondary Structure
MRFVDEYRSNEKVQTLLEAIRKKVTRPWYIMEICGGQTHAIARYRLEEMLPPDLQLLHGP
CCCHHHHCCCHHHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHHCCCCCEEEECC
GCPVCVTPVETIDYALKLATQPNVILASFGDMMRVPGSKEDLLSVKARGADIRMLYTPLD
CCCEEECCHHHHHHHHHHCCCCCEEEECCCHHHCCCCCHHHHHHHHCCCCCEEEEECCHH
ALSLAEENPDKEIVFFAIGFETTAPVHLMALKEAIRRGLPNFSILTSLFTVPPAIEAILS
HHHHHCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHCCHHHHHHHC
DPESKVDGFLTAGHVCAITGNRAYHRLTARYKIPMVVTGFEPVDLLYGIYRCVSQLEAGS
CCHHHHCCCEECCEEEEEECCCHHHEEEEEEECCEEEECCCHHHHHHHHHHHHHHHCCCC
YEVENAYKRAVPEQGNAAARQLMDEMLEPCDQDWRGIGIIPSSGLQLRSEYKRYSSRMRF
CHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHCCEE
QLCPEENQIASECIAGLIMRGLRHPSDCPHFGKACHPTHPLGAPMVSSEGVCAAYYRYK
EECCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1849603; 9278503 [H]