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The map label for this gene is hypA

Identifier: 150008424

GI number: 150008424

Start: 2154569

End: 2154916

Strand: Reverse

Name: hypA

Synonym: BDI_1806

Alternate gene names: 150008424

Gene position: 2154916-2154569 (Counterclockwise)

Preceding gene: 150008425

Following gene: 150008423

Centisome position: 44.79

GC content: 47.41

Gene sequence:

>348_bases
ATGCATGAGTTGTCTATAGCCCGTAGCATCGTGGAGCTGGTCGAGGAACAAGCGGATAACCGGGGAGCCTCGGTGGTCGA
AGAGTTGGAGTTAGAGATAGGACATTTGTCCGGCGTAGAGATCCAAACCTTAGAGTTCGCATTGGATAGCGCCATAAAAG
GTAGCAAGCTGGAAAAGGCCCGGATTATCCGTCATTATATTGAGGGGGAAGGACAGTGTAGCGACTGTGAGACCATTTTC
CCAATGAACGCCTTGTTTTCCCCTTGTCCCCATTGTGGCTCCTATTTAGTTAAAATCCTTAAAGGGAAGGAACTTCGGGT
GAAGTCGATTGTTATTAAAAAGGAATGA

Upstream 100 bases:

>100_bases
CCCCGTCTATATTCCGTCTCGTATACCTTGTAACGATGGGGGGATAGCCGTGGGGCAATTAACGATCGCCTCGGTGACTC
CCTTTTAAAAGAGATCAGAT

Downstream 100 bases:

>100_bases
TATATTAATGAAATAAAAACTTAAATACTATGTGCGGAACTTGCGGATGCGGAGAGCATCATCACCATCACGATCATATG
CATGAGCATTCTCATGGCCA

Product: hydrogenase expression/formation protein HupA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 115; Mature: 115

Protein sequence:

>115_residues
MHELSIARSIVELVEEQADNRGASVVEELELEIGHLSGVEIQTLEFALDSAIKGSKLEKARIIRHYIEGEGQCSDCETIF
PMNALFSPCPHCGSYLVKILKGKELRVKSIVIKKE

Sequences:

>Translated_115_residues
MHELSIARSIVELVEEQADNRGASVVEELELEIGHLSGVEIQTLEFALDSAIKGSKLEKARIIRHYIEGEGQCSDCETIF
PMNALFSPCPHCGSYLVKILKGKELRVKSIVIKKE
>Mature_115_residues
MHELSIARSIVELVEEQADNRGASVVEELELEIGHLSGVEIQTLEFALDSAIKGSKLEKARIIRHYIEGEGQCSDCETIF
PMNALFSPCPHCGSYLVKILKGKELRVKSIVIKKE

Specific function: Probably plays a role in an hydrogenase nickel cofactor insertion step

COG id: COG0375

COG function: function code R; Zn finger protein HypA/HybF (possibly regulating hydrogenase expression)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hypA/hybF family

Homologues:

Organism=Escherichia coli, GI1789081, Length=119, Percent_Identity=32.7731092436975, Blast_Score=61, Evalue=1e-11,
Organism=Escherichia coli, GI1789365, Length=110, Percent_Identity=30.9090909090909, Blast_Score=59, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): HYPA_PARD8 (A6LCY1)

Other databases:

- EMBL:   CP000140
- RefSeq:   YP_001303167.1
- STRING:   A6LCY1
- GeneID:   5306956
- GenomeReviews:   CP000140_GR
- KEGG:   pdi:BDI_1806
- eggNOG:   COG0375
- HOGENOM:   HBG688671
- OMA:   KEFMIKE
- BioCyc:   PDIS435591:BDI_1806-MONOMER
- HAMAP:   MF_00213
- InterPro:   IPR000688
- TIGRFAMs:   TIGR00100

Pfam domain/function: PF01155 HypA

EC number: NA

Molecular weight: Translated: 12795; Mature: 12795

Theoretical pI: Translated: 5.25; Mature: 5.25

Prosite motif: PS01249 HYPA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.5 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
3.5 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHELSIARSIVELVEEQADNRGASVVEELELEIGHLSGVEIQTLEFALDSAIKGSKLEKA
CCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCHHHH
RIIRHYIEGEGQCSDCETIFPMNALFSPCPHCGSYLVKILKGKELRVKSIVIKKE
HHHHHHHCCCCCCCCCCHHCCCHHHHCCCCHHHHHHHHHHCCCCEEEEEEEEECC
>Mature Secondary Structure
MHELSIARSIVELVEEQADNRGASVVEELELEIGHLSGVEIQTLEFALDSAIKGSKLEKA
CCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCHHHH
RIIRHYIEGEGQCSDCETIFPMNALFSPCPHCGSYLVKILKGKELRVKSIVIKKE
HHHHHHHCCCCCCCCCCHHCCCHHHHCCCCHHHHHHHHHHCCCCEEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA