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The map label for this gene is zraR [H]

Identifier: 150008022

GI number: 150008022

Start: 1606354

End: 1607703

Strand: Direct

Name: zraR [H]

Synonym: BDI_1385

Alternate gene names: 150008022

Gene position: 1606354-1607703 (Clockwise)

Preceding gene: 150008020

Following gene: 150008023

Centisome position: 33.39

GC content: 51.04

Gene sequence:

>1350_bases
ATGGCAAAACAAGGCACTATACTAGTTGTGGATGATAATAAAGGTATCCTGACCGCCGTACAAATGCTGTTAGGAACTTG
CTTCGAGAAGGTTATCACCATCTCTACCCCGAACAAGATAAAAAACACGCTGCACGACGAGAACGTGGATGTCGTATTGC
TCGACATGAATTTCAGCGCCGGTATAAACAGCGGCAACGAGGGGTTGTTCTGGCTCTCCGAGATCAAGAAGGCTTATCCC
TCGATACAAGTCGTTCTCTTTACCGCCTACGCCGACATCGATCTGGCGGTACGAGGAATCAAGGAAGGGGCTACCGATTT
CGTGGTAAAGCCTTGGGACAACGCTAAATTATTGGAAACCTTGCAAGCCGCTTACCAAATCCGCTCGGCCAATCATAAAG
GCGGTGTCGGCAACAAGCAGTTGGTATCCAAGGAAAGCGGTATGTTCTGGGGAGACAGCAACGCCATGCAGCAACTACGG
ATGCTGATAGAGAAAGTAGCCAAGACAGACGCCAATATATTAATCACGGGAGAGAACGGAACCGGTAAGGAAATGCTGGC
CCGGGAAATACACCTGCTATCCCCCCGCAAGGATGAGGCCATGGTACCGGTGGATATGGGCGCTATCACGGAGACGCTGT
TCGAGAGCGAGCTGTTCGGACACGTAAAAGGGGCCTTCACCGACGCCCGGACGGATCGCCCCGGTAAGTTCGAGGTAGCG
AACAACGGAAGCTTGTTCCTCGACGAGATCGGTAACCTGTCTTATCATCTGCAAGCCAAATTACTGACCGCCTTGCAACG
CCGGAGCATCGTACGGGTAGGTAGCAATACCCCGATCCCCATCAATATCCGCCTGATCTGCGCCACGAACCGGGACTTGC
AGGAGATGGTACAGAAAGAGCAATTCCGCGAGGACTTGCTGTATCGTATCAATACGATACACGTAGAGATCCCGCCCTTG
AGGGAGCGGCCGGAGGATATCGTACCGCTTGCTGAGATATTCATCACGAAATATACCAATATCTACGGTAAAAAGCCCAT
GGCCCTCACCGACGACGCCAAGGAAAAGCTGAAAGCCCAACCTTGGCTGGGTAATATCCGCGAACTGGAACATACCGTGG
AGAAAGCGATTATCATTGCCGATGGTGATACTTTAGATGGCAGCAATTTCGATTTCCCTCGTAAGCGGGAGGCGCCCGTC
AAGAATGACATCACTACGCTCGAGGAAATGGAGTATACTATGATCAAGGCCGCCATGGATAAATTTGGCGGTAATCTCTC
GCTCGTGGCGAACCAGTTGGGTATCTCACGGCAAACGCTTTATAATAAGATCAAGCGGTATGAACTTTAA

Upstream 100 bases:

>100_bases
ATTTCTTTATCCATACGGTATATGAAACAGAAATAGGATGTATCTGGTTTAGGAAGTATCGACCAGATCGAGTATCTTTG
CCCGTATAAATGGACATGAC

Downstream 100 bases:

>100_bases
AGGCATTTATTACAGCCTCACCTTCCGCCTCGCCCTCGCTATCGGGCTGACGGCGGCACTCACCTACCAGGCCTTGGAGA
AAGAATGGGGATGGTTCCTG

Product: two-component system response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 449; Mature: 448

Protein sequence:

>449_residues
MAKQGTILVVDDNKGILTAVQMLLGTCFEKVITISTPNKIKNTLHDENVDVVLLDMNFSAGINSGNEGLFWLSEIKKAYP
SIQVVLFTAYADIDLAVRGIKEGATDFVVKPWDNAKLLETLQAAYQIRSANHKGGVGNKQLVSKESGMFWGDSNAMQQLR
MLIEKVAKTDANILITGENGTGKEMLAREIHLLSPRKDEAMVPVDMGAITETLFESELFGHVKGAFTDARTDRPGKFEVA
NNGSLFLDEIGNLSYHLQAKLLTALQRRSIVRVGSNTPIPINIRLICATNRDLQEMVQKEQFREDLLYRINTIHVEIPPL
RERPEDIVPLAEIFITKYTNIYGKKPMALTDDAKEKLKAQPWLGNIRELEHTVEKAIIIADGDTLDGSNFDFPRKREAPV
KNDITTLEEMEYTMIKAAMDKFGGNLSLVANQLGISRQTLYNKIKRYEL

Sequences:

>Translated_449_residues
MAKQGTILVVDDNKGILTAVQMLLGTCFEKVITISTPNKIKNTLHDENVDVVLLDMNFSAGINSGNEGLFWLSEIKKAYP
SIQVVLFTAYADIDLAVRGIKEGATDFVVKPWDNAKLLETLQAAYQIRSANHKGGVGNKQLVSKESGMFWGDSNAMQQLR
MLIEKVAKTDANILITGENGTGKEMLAREIHLLSPRKDEAMVPVDMGAITETLFESELFGHVKGAFTDARTDRPGKFEVA
NNGSLFLDEIGNLSYHLQAKLLTALQRRSIVRVGSNTPIPINIRLICATNRDLQEMVQKEQFREDLLYRINTIHVEIPPL
RERPEDIVPLAEIFITKYTNIYGKKPMALTDDAKEKLKAQPWLGNIRELEHTVEKAIIIADGDTLDGSNFDFPRKREAPV
KNDITTLEEMEYTMIKAAMDKFGGNLSLVANQLGISRQTLYNKIKRYEL
>Mature_448_residues
AKQGTILVVDDNKGILTAVQMLLGTCFEKVITISTPNKIKNTLHDENVDVVLLDMNFSAGINSGNEGLFWLSEIKKAYPS
IQVVLFTAYADIDLAVRGIKEGATDFVVKPWDNAKLLETLQAAYQIRSANHKGGVGNKQLVSKESGMFWGDSNAMQQLRM
LIEKVAKTDANILITGENGTGKEMLAREIHLLSPRKDEAMVPVDMGAITETLFESELFGHVKGAFTDARTDRPGKFEVAN
NGSLFLDEIGNLSYHLQAKLLTALQRRSIVRVGSNTPIPINIRLICATNRDLQEMVQKEQFREDLLYRINTIHVEIPPLR
ERPEDIVPLAEIFITKYTNIYGKKPMALTDDAKEKLKAQPWLGNIRELEHTVEKAIIIADGDTLDGSNFDFPRKREAPVK
NDITTLEEMEYTMIKAAMDKFGGNLSLVANQLGISRQTLYNKIKRYEL

Specific function: Member of the two-component regulatory system zraS/zraR. When activated by zraS it acts in conjunction with sigma-54 to regulate the expression of zraP. Positively autoregulates the expression of the zraSR operon [H]

COG id: COG2204

COG function: function code T; Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1790437, Length=445, Percent_Identity=39.5505617977528, Blast_Score=291, Evalue=6e-80,
Organism=Escherichia coli, GI1788550, Length=464, Percent_Identity=38.1465517241379, Blast_Score=271, Evalue=8e-74,
Organism=Escherichia coli, GI1790299, Length=474, Percent_Identity=32.9113924050633, Blast_Score=244, Evalue=6e-66,
Organism=Escherichia coli, GI87082117, Length=312, Percent_Identity=41.9871794871795, Blast_Score=241, Evalue=7e-65,
Organism=Escherichia coli, GI1788905, Length=456, Percent_Identity=33.5526315789474, Blast_Score=237, Evalue=1e-63,
Organism=Escherichia coli, GI1789233, Length=317, Percent_Identity=40.6940063091483, Blast_Score=236, Evalue=3e-63,
Organism=Escherichia coli, GI1789087, Length=310, Percent_Identity=41.2903225806452, Blast_Score=232, Evalue=4e-62,
Organism=Escherichia coli, GI87082152, Length=274, Percent_Identity=44.1605839416058, Blast_Score=219, Evalue=4e-58,
Organism=Escherichia coli, GI1786524, Length=315, Percent_Identity=36.1904761904762, Blast_Score=194, Evalue=8e-51,
Organism=Escherichia coli, GI1787583, Length=293, Percent_Identity=35.8361774744027, Blast_Score=181, Evalue=1e-46,
Organism=Escherichia coli, GI87081872, Length=229, Percent_Identity=41.4847161572052, Blast_Score=179, Evalue=3e-46,
Organism=Escherichia coli, GI1789828, Length=227, Percent_Identity=38.7665198237885, Blast_Score=136, Evalue=2e-33,
Organism=Escherichia coli, GI87081858, Length=302, Percent_Identity=28.1456953642384, Blast_Score=114, Evalue=2e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR011006
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR002078
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02954 HTH_8; PF00072 Response_reg; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 50254; Mature: 50122

Theoretical pI: Translated: 6.21; Mature: 6.21

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00676 SIGMA54_INTERACT_2 ; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKQGTILVVDDNKGILTAVQMLLGTCFEKVITISTPNKIKNTLHDENVDVVLLDMNFSA
CCCCCEEEEEECCCCHHHHHHHHHHHHHHHHEECCCCHHHHHHHCCCCCCEEEEEECCCC
GINSGNEGLFWLSEIKKAYPSIQVVLFTAYADIDLAVRGIKEGATDFVVKPWDNAKLLET
CCCCCCCCEEEHHHHHHHCCCEEEEEEEEECCHHHHHHHHHCCCCCEEEECCCCHHHHHH
LQAAYQIRSANHKGGVGNKQLVSKESGMFWGDSNAMQQLRMLIEKVAKTDANILITGENG
HHHHHHHHCCCCCCCCCCHHHHHCCCCCEECCHHHHHHHHHHHHHHHCCCCCEEEECCCC
TGKEMLAREIHLLSPRKDEAMVPVDMGAITETLFESELFGHVKGAFTDARTDRPGKFEVA
CCHHHHHHHHHHCCCCCCCCCCEECHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEE
NNGSLFLDEIGNLSYHLQAKLLTALQRRSIVRVGSNTPIPINIRLICATNRDLQEMVQKE
CCCCEEEEHHCCCEEHHHHHHHHHHHHCCEEEECCCCCEEEEEEEEEECCHHHHHHHHHH
QFREDLLYRINTIHVEIPPLRERPEDIVPLAEIFITKYTNIYGKKPMALTDDAKEKLKAQ
HHHHHHHHEEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCEECCCHHHHHCCC
PWLGNIRELEHTVEKAIIIADGDTLDGSNFDFPRKREAPVKNDITTLEEMEYTMIKAAMD
CCCCHHHHHHHHHHEEEEEECCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHH
KFGGNLSLVANQLGISRQTLYNKIKRYEL
HHCCCCEEHHHHHCCHHHHHHHHHHHCCC
>Mature Secondary Structure 
AKQGTILVVDDNKGILTAVQMLLGTCFEKVITISTPNKIKNTLHDENVDVVLLDMNFSA
CCCCEEEEEECCCCHHHHHHHHHHHHHHHHEECCCCHHHHHHHCCCCCCEEEEEECCCC
GINSGNEGLFWLSEIKKAYPSIQVVLFTAYADIDLAVRGIKEGATDFVVKPWDNAKLLET
CCCCCCCCEEEHHHHHHHCCCEEEEEEEEECCHHHHHHHHHCCCCCEEEECCCCHHHHHH
LQAAYQIRSANHKGGVGNKQLVSKESGMFWGDSNAMQQLRMLIEKVAKTDANILITGENG
HHHHHHHHCCCCCCCCCCHHHHHCCCCCEECCHHHHHHHHHHHHHHHCCCCCEEEECCCC
TGKEMLAREIHLLSPRKDEAMVPVDMGAITETLFESELFGHVKGAFTDARTDRPGKFEVA
CCHHHHHHHHHHCCCCCCCCCCEECHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEE
NNGSLFLDEIGNLSYHLQAKLLTALQRRSIVRVGSNTPIPINIRLICATNRDLQEMVQKE
CCCCEEEEHHCCCEEHHHHHHHHHHHHCCEEEECCCCCEEEEEEEEEECCHHHHHHHHHH
QFREDLLYRINTIHVEIPPLRERPEDIVPLAEIFITKYTNIYGKKPMALTDDAKEKLKAQ
HHHHHHHHEEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCEECCCHHHHHCCC
PWLGNIRELEHTVEKAIIIADGDTLDGSNFDFPRKREAPVKNDITTLEEMEYTMIKAAMD
CCCCHHHHHHHHHHEEEEEECCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHH
KFGGNLSLVANQLGISRQTLYNKIKRYEL
HHCCCCEEHHHHHCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11243806 [H]