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The map label for this gene is ntrY [H]

Identifier: 150008023

GI number: 150008023

Start: 1607693

End: 1609012

Strand: Direct

Name: ntrY [H]

Synonym: BDI_1386

Alternate gene names: 150008023

Gene position: 1607693-1609012 (Clockwise)

Preceding gene: 150008022

Following gene: 150008024

Centisome position: 33.41

GC content: 53.64

Gene sequence:

>1320_bases
ATGAACTTTAAAGGCATTTATTACAGCCTCACCTTCCGCCTCGCCCTCGCTATCGGGCTGACGGCGGCACTCACCTACCA
GGCCTTGGAGAAAGAATGGGGATGGTTCCTGTTCTTAGGCATCGGATGGCTGGCTGCCTTGCGGGGCATCAGCCTTTTGT
TCAAGCGGAACGCGCAAAAGGTAGCCTTCATGTTCGACGCGATCGACAATAGCGATTACGCCTTCAAGTACGCTACCCGG
GGGCGCTCCTCCAACGACAAGCTGGTTAGCGAGTCCTTAAACCGCATCACCCAAATACTTTTTCAAGCGAAAGCCGAGGC
GATCCAGAAAGAGAAATATTACGAGTTGATCATGAACCAAGTGAATACGGGTATCATCGTAGAAGATGATAAGGGCAATA
TTTTCCAGACCAACAACGAGGCCTTGCGACTGCTGGGATTGACGGTCTTTACCCATGCCCGCCAGCTCGGACGTATCGAC
GAGAATCTAGAGCGCCTCATCAGCGACGTTCGTCCCGGCGAGAAACATCAGATCTCTTTTATCAACGAGCGGGGCACGGT
ACATCTCTCGGTCCGTGTCTCCGAGATGACGCTCCAAGAGAAACACGTCCGCATCATTGCGATCAATGATATCAACAGCG
AGCTGGACGATAAGGAGATCGAGTCATGGATACGACTGACACGGGTCTTGACCCATGAGATCATGAACTCCGTCACCCCT
ATCACCTCCTTGAGCGACACCTTGCTTTCCCTCCACCAGAATGTCGACGAGGAGATACGGGGCGGCTTGGAGGTAATCAG
CTCTACCGGAAAGAGCTTGATCGCGTTCGTCGAGTCGTACCGTAAGTTTACACATATACCGACGCCTCAGCCCTCTTTAT
TCTACGTCAATAAGTTCGCCGAACGGCTCACGCGGTTGGCCCGCCACCACAATAACTACCCGAACATAACCATTCGTATC
GACGTGGAACCGGAGGACTTGATCGTCTACGCCGACGAGAACCTGATCACGCAAGTAGTCTTGAACCTCTTGAAGAACGC
CATGCAAGCGATCGGGCACGAGCAAGAAAACGGCCTTATCTTGTTCAAGGCGTATTGCGACCCCAACGAGGCCGTTATCC
TAGAAGTGACGAACAACGGCCCCATCATCCCCCCCGAGGAAGCCGAGCATATATTCGTGCCGTTCTTCACCACGAAAGAA
GGTGGAAGCGGTATCGGGCTGTCCATCTCACGACAGATCATGCGCTTGTCCGGCGGCAGCATCGCATTGAGAAGCAACCC
GGCCCAGCGGCAGACCACCTTCGTGTTGACATTCCCGTAG

Upstream 100 bases:

>100_bases
ATGATCAAGGCCGCCATGGATAAATTTGGCGGTAATCTCTCGCTCGTGGCGAACCAGTTGGGTATCTCACGGCAAACGCT
TTATAATAAGATCAAGCGGT

Downstream 100 bases:

>100_bases
CTCGTTTACCGTATCCGCATAAACGCGGACACGCGGCCGGGCGGATACGCGGACACACAAGCCCGGATACACGGGCGCGA
CCGTACGGGTACACCCGCGT

Product: putative two-component system sensor histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 439; Mature: 439

Protein sequence:

>439_residues
MNFKGIYYSLTFRLALAIGLTAALTYQALEKEWGWFLFLGIGWLAALRGISLLFKRNAQKVAFMFDAIDNSDYAFKYATR
GRSSNDKLVSESLNRITQILFQAKAEAIQKEKYYELIMNQVNTGIIVEDDKGNIFQTNNEALRLLGLTVFTHARQLGRID
ENLERLISDVRPGEKHQISFINERGTVHLSVRVSEMTLQEKHVRIIAINDINSELDDKEIESWIRLTRVLTHEIMNSVTP
ITSLSDTLLSLHQNVDEEIRGGLEVISSTGKSLIAFVESYRKFTHIPTPQPSLFYVNKFAERLTRLARHHNNYPNITIRI
DVEPEDLIVYADENLITQVVLNLLKNAMQAIGHEQENGLILFKAYCDPNEAVILEVTNNGPIIPPEEAEHIFVPFFTTKE
GGSGIGLSISRQIMRLSGGSIALRSNPAQRQTTFVLTFP

Sequences:

>Translated_439_residues
MNFKGIYYSLTFRLALAIGLTAALTYQALEKEWGWFLFLGIGWLAALRGISLLFKRNAQKVAFMFDAIDNSDYAFKYATR
GRSSNDKLVSESLNRITQILFQAKAEAIQKEKYYELIMNQVNTGIIVEDDKGNIFQTNNEALRLLGLTVFTHARQLGRID
ENLERLISDVRPGEKHQISFINERGTVHLSVRVSEMTLQEKHVRIIAINDINSELDDKEIESWIRLTRVLTHEIMNSVTP
ITSLSDTLLSLHQNVDEEIRGGLEVISSTGKSLIAFVESYRKFTHIPTPQPSLFYVNKFAERLTRLARHHNNYPNITIRI
DVEPEDLIVYADENLITQVVLNLLKNAMQAIGHEQENGLILFKAYCDPNEAVILEVTNNGPIIPPEEAEHIFVPFFTTKE
GGSGIGLSISRQIMRLSGGSIALRSNPAQRQTTFVLTFP
>Mature_439_residues
MNFKGIYYSLTFRLALAIGLTAALTYQALEKEWGWFLFLGIGWLAALRGISLLFKRNAQKVAFMFDAIDNSDYAFKYATR
GRSSNDKLVSESLNRITQILFQAKAEAIQKEKYYELIMNQVNTGIIVEDDKGNIFQTNNEALRLLGLTVFTHARQLGRID
ENLERLISDVRPGEKHQISFINERGTVHLSVRVSEMTLQEKHVRIIAINDINSELDDKEIESWIRLTRVLTHEIMNSVTP
ITSLSDTLLSLHQNVDEEIRGGLEVISSTGKSLIAFVESYRKFTHIPTPQPSLFYVNKFAERLTRLARHHNNYPNITIRI
DVEPEDLIVYADENLITQVVLNLLKNAMQAIGHEQENGLILFKAYCDPNEAVILEVTNNGPIIPPEEAEHIFVPFFTTKE
GGSGIGLSISRQIMRLSGGSIALRSNPAQRQTTFVLTFP

Specific function: Member of the two-component regulatory system ntrY/ntrX involved in nitrogen level control. Probably activates ntrX by phosphorylation [H]

COG id: COG5000

COG function: function code T; Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1790436, Length=119, Percent_Identity=37.8151260504202, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI1788549, Length=378, Percent_Identity=24.6031746031746, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI1790300, Length=154, Percent_Identity=31.8181818181818, Blast_Score=69, Evalue=9e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR017232 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 49740; Mature: 49740

Theoretical pI: Translated: 6.45; Mature: 6.45

Prosite motif: PS50112 PAS ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNFKGIYYSLTFRLALAIGLTAALTYQALEKEWGWFLFLGIGWLAALRGISLLFKRNAQK
CCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHCCCCE
VAFMFDAIDNSDYAFKYATRGRSSNDKLVSESLNRITQILFQAKAEAIQKEKYYELIMNQ
EEEEEEECCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VNTGIIVEDDKGNIFQTNNEALRLLGLTVFTHARQLGRIDENLERLISDVRPGEKHQISF
CCCCEEEECCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEE
INERGTVHLSVRVSEMTLQEKHVRIIAINDINSELDDKEIESWIRLTRVLTHEIMNSVTP
EECCCEEEEEEEEEHHHHCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHCCC
ITSLSDTLLSLHQNVDEEIRGGLEVISSTGKSLIAFVESYRKFTHIPTPQPSLFYVNKFA
HHHHHHHHHHHHHCCCHHHHHHHHHHHHCHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHH
ERLTRLARHHNNYPNITIRIDVEPEDLIVYADENLITQVVLNLLKNAMQAIGHEQENGLI
HHHHHHHHHCCCCCCEEEEEEECCCCEEEEECCHHHHHHHHHHHHHHHHHCCCCCCCCEE
LFKAYCDPNEAVILEVTNNGPIIPPEEAEHIFVPFFTTKEGGSGIGLSISRQIMRLSGGS
EEEEECCCCCEEEEEECCCCCCCCCCCCCEEEEEEEEECCCCCCCCHHHHHHHHHHCCCE
IALRSNPAQRQTTFVLTFP
EEEECCCCCCCEEEEEECC
>Mature Secondary Structure
MNFKGIYYSLTFRLALAIGLTAALTYQALEKEWGWFLFLGIGWLAALRGISLLFKRNAQK
CCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHCCCCE
VAFMFDAIDNSDYAFKYATRGRSSNDKLVSESLNRITQILFQAKAEAIQKEKYYELIMNQ
EEEEEEECCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VNTGIIVEDDKGNIFQTNNEALRLLGLTVFTHARQLGRIDENLERLISDVRPGEKHQISF
CCCCEEEECCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEE
INERGTVHLSVRVSEMTLQEKHVRIIAINDINSELDDKEIESWIRLTRVLTHEIMNSVTP
EECCCEEEEEEEEEHHHHCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHCCC
ITSLSDTLLSLHQNVDEEIRGGLEVISSTGKSLIAFVESYRKFTHIPTPQPSLFYVNKFA
HHHHHHHHHHHHHCCCHHHHHHHHHHHHCHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHH
ERLTRLARHHNNYPNITIRIDVEPEDLIVYADENLITQVVLNLLKNAMQAIGHEQENGLI
HHHHHHHHHCCCCCCEEEEEEECCCCEEEEECCHHHHHHHHHHHHHHHHHCCCCCCCCEE
LFKAYCDPNEAVILEVTNNGPIIPPEEAEHIFVPFFTTKEGGSGIGLSISRQIMRLSGGS
EEEEECCCCCEEEEEECCCCCCCCCCCCCEEEEEEEEECCCCCCCCHHHHHHHHHHCCCE
IALRSNPAQRQTTFVLTFP
EEEECCCCCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1661370 [H]