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The map label for this gene is gatD [H]

Identifier: 150007988

GI number: 150007988

Start: 1569164

End: 1570207

Strand: Reverse

Name: gatD [H]

Synonym: BDI_1350

Alternate gene names: 150007988

Gene position: 1570207-1569164 (Counterclockwise)

Preceding gene: 150007989

Following gene: 150007987

Centisome position: 32.64

GC content: 34.96

Gene sequence:

>1044_bases
ATGAAAGCAAATGTGTTATTTGGTATAGGTGATTTAAAGTATACGAATATACCACTGCCTAGATTAAAATCAGATGAAGT
ATTAGTTAAAGTTAAGGCGGCTGGGATTTGTGGATCGGATATTGCTAGAGTATTTAAAACTGGAACATATCATTTTCCTA
CTGTTATAGGTCATGAATTTTCAGGTGTAGTTAGTGATATTGGAAGTTCAACATATTTATCTTGGTTGGGTAAGCGAGTG
TCTGTTTTCCCTTTGAAACCTTGTTTTAAGTGTAATAATTGTAAAAATAAGGAATATGAATTATGTTCGAATTATGATTA
CTTAGGATCAAGATGTAATGGGGGTTTTGCGGAATATGTTGCTGTTCCTGTTTGGAATCTCTTGGAGATTCCGGATTGCG
TTTGTTATGAAGAAGCGGCTATGCTAGAACCAGCAGCGGTTGCCTTACATGCATTAAAACGATCTGGTTTTAAAAAAGGA
GATACAGTTGTTGTTATCGGTCCAGGAACAATTGGGATGATATTATCTCAAATGGTAAAACTTTTGGGAGCATCAAAAGT
GGTATTAGTAGGTAGGACTCAAACAAAGTTGGATTTTGCAAAGACTTATGGGGTAGAGAATATCTGTAATTCTACTACTT
CAGATGTATCTGAATGGGTATCAAGGAATATAGATAGCTCCGGAGCCGATATTGTTTTTGAGGGGACTGGGGCATCTATG
TCGTTCAATACTAGCTTGAAAATAGTGAAATCTTCGGGTACTATTGTTGCTTTAGGTAATCCAATTGATGATATGACTTT
AGAGAAAGATTTTTATTGGAAACTATTGCGAAAGCAATTGCAGATTTATGGTACTTGGAACTCTAGTTTTGGCATCAATG
ATAATGATTGGACTCAAGTTTTATATTGGTTGGAGAATGAAAAATTGGATCTCAAAAGATTGATTACCCATCGTTTGGAT
TTTAGCCAGTTAATGGAAGGCTTGATGCTTATGCGTGATAATTCTATTTATTCAAATAAAGTAATGTTGGTAGATCATGA
ATAG

Upstream 100 bases:

>100_bases
ATAAGGCAGGAATGAAAGTAAAGTTAATAAAAGGTGATGAACGAAATTTTAAAGTAACGGTACCGGAGGATTTAGTTCGT
TTAAAATTATTGTTGGAAAA

Downstream 100 bases:

>100_bases
AATATCTAAATTATCCGTTTCGCTTATGTGTGCTGACTTGGTAAACTTGGAGCGTGACATCCATATTTTAGAAGAAAATG
GAGTTGATTATTTACATGTA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 347; Mature: 347

Protein sequence:

>347_residues
MKANVLFGIGDLKYTNIPLPRLKSDEVLVKVKAAGICGSDIARVFKTGTYHFPTVIGHEFSGVVSDIGSSTYLSWLGKRV
SVFPLKPCFKCNNCKNKEYELCSNYDYLGSRCNGGFAEYVAVPVWNLLEIPDCVCYEEAAMLEPAAVALHALKRSGFKKG
DTVVVIGPGTIGMILSQMVKLLGASKVVLVGRTQTKLDFAKTYGVENICNSTTSDVSEWVSRNIDSSGADIVFEGTGASM
SFNTSLKIVKSSGTIVALGNPIDDMTLEKDFYWKLLRKQLQIYGTWNSSFGINDNDWTQVLYWLENEKLDLKRLITHRLD
FSQLMEGLMLMRDNSIYSNKVMLVDHE

Sequences:

>Translated_347_residues
MKANVLFGIGDLKYTNIPLPRLKSDEVLVKVKAAGICGSDIARVFKTGTYHFPTVIGHEFSGVVSDIGSSTYLSWLGKRV
SVFPLKPCFKCNNCKNKEYELCSNYDYLGSRCNGGFAEYVAVPVWNLLEIPDCVCYEEAAMLEPAAVALHALKRSGFKKG
DTVVVIGPGTIGMILSQMVKLLGASKVVLVGRTQTKLDFAKTYGVENICNSTTSDVSEWVSRNIDSSGADIVFEGTGASM
SFNTSLKIVKSSGTIVALGNPIDDMTLEKDFYWKLLRKQLQIYGTWNSSFGINDNDWTQVLYWLENEKLDLKRLITHRLD
FSQLMEGLMLMRDNSIYSNKVMLVDHE
>Mature_347_residues
MKANVLFGIGDLKYTNIPLPRLKSDEVLVKVKAAGICGSDIARVFKTGTYHFPTVIGHEFSGVVSDIGSSTYLSWLGKRV
SVFPLKPCFKCNNCKNKEYELCSNYDYLGSRCNGGFAEYVAVPVWNLLEIPDCVCYEEAAMLEPAAVALHALKRSGFKKG
DTVVVIGPGTIGMILSQMVKLLGASKVVLVGRTQTKLDFAKTYGVENICNSTTSDVSEWVSRNIDSSGADIVFEGTGASM
SFNTSLKIVKSSGTIVALGNPIDDMTLEKDFYWKLLRKQLQIYGTWNSSFGINDNDWTQVLYWLENEKLDLKRLITHRLD
FSQLMEGLMLMRDNSIYSNKVMLVDHE

Specific function: Converts galactitol 1-phosphate to tagatose 6-phosphate [H]

COG id: COG1063

COG function: function code ER; Threonine dehydrogenase and related Zn-dependent dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI156627571, Length=335, Percent_Identity=28.955223880597, Blast_Score=140, Evalue=1e-33,
Organism=Homo sapiens, GI71743840, Length=353, Percent_Identity=26.628895184136, Blast_Score=92, Evalue=7e-19,
Organism=Homo sapiens, GI262073058, Length=353, Percent_Identity=26.628895184136, Blast_Score=92, Evalue=7e-19,
Organism=Homo sapiens, GI4501933, Length=341, Percent_Identity=25.8064516129032, Blast_Score=80, Evalue=4e-15,
Organism=Homo sapiens, GI4501929, Length=338, Percent_Identity=25.7396449704142, Blast_Score=79, Evalue=5e-15,
Organism=Homo sapiens, GI156523966, Length=343, Percent_Identity=23.6151603498542, Blast_Score=79, Evalue=7e-15,
Organism=Homo sapiens, GI4501939, Length=343, Percent_Identity=23.9067055393586, Blast_Score=79, Evalue=8e-15,
Organism=Escherichia coli, GI1788407, Length=328, Percent_Identity=32.6219512195122, Blast_Score=197, Evalue=7e-52,
Organism=Escherichia coli, GI1790045, Length=333, Percent_Identity=29.4294294294294, Blast_Score=150, Evalue=1e-37,
Organism=Escherichia coli, GI1788073, Length=327, Percent_Identity=28.1345565749235, Blast_Score=150, Evalue=2e-37,
Organism=Escherichia coli, GI1788075, Length=357, Percent_Identity=29.1316526610644, Blast_Score=147, Evalue=1e-36,
Organism=Escherichia coli, GI1787863, Length=347, Percent_Identity=27.3775216138329, Blast_Score=141, Evalue=5e-35,
Organism=Escherichia coli, GI226510992, Length=315, Percent_Identity=27.3015873015873, Blast_Score=135, Evalue=3e-33,
Organism=Escherichia coli, GI1790718, Length=328, Percent_Identity=27.4390243902439, Blast_Score=119, Evalue=3e-28,
Organism=Escherichia coli, GI87082125, Length=333, Percent_Identity=25.8258258258258, Blast_Score=107, Evalue=2e-24,
Organism=Escherichia coli, GI1786825, Length=387, Percent_Identity=24.5478036175711, Blast_Score=92, Evalue=7e-20,
Organism=Escherichia coli, GI87081918, Length=340, Percent_Identity=25.5882352941176, Blast_Score=82, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI17562876, Length=326, Percent_Identity=30.0613496932515, Blast_Score=152, Evalue=2e-37,
Organism=Caenorhabditis elegans, GI17562878, Length=340, Percent_Identity=27.0588235294118, Blast_Score=139, Evalue=2e-33,
Organism=Caenorhabditis elegans, GI71988145, Length=264, Percent_Identity=26.1363636363636, Blast_Score=84, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17562584, Length=262, Percent_Identity=27.4809160305344, Blast_Score=72, Evalue=4e-13,
Organism=Saccharomyces cerevisiae, GI6322619, Length=335, Percent_Identity=30.7462686567164, Blast_Score=155, Evalue=6e-39,
Organism=Saccharomyces cerevisiae, GI6319955, Length=335, Percent_Identity=30.7462686567164, Blast_Score=155, Evalue=7e-39,
Organism=Saccharomyces cerevisiae, GI6323099, Length=338, Percent_Identity=30.4733727810651, Blast_Score=151, Evalue=1e-37,
Organism=Saccharomyces cerevisiae, GI6319258, Length=286, Percent_Identity=32.5174825174825, Blast_Score=135, Evalue=1e-32,
Organism=Saccharomyces cerevisiae, GI6319257, Length=376, Percent_Identity=25.2659574468085, Blast_Score=109, Evalue=6e-25,
Organism=Saccharomyces cerevisiae, GI6319520, Length=260, Percent_Identity=27.6923076923077, Blast_Score=81, Evalue=3e-16,
Organism=Saccharomyces cerevisiae, GI6324486, Length=264, Percent_Identity=25.7575757575758, Blast_Score=74, Evalue=3e-14,
Organism=Saccharomyces cerevisiae, GI6323729, Length=270, Percent_Identity=25.9259259259259, Blast_Score=72, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6319621, Length=257, Percent_Identity=25.6809338521401, Blast_Score=72, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6320033, Length=353, Percent_Identity=22.6628895184136, Blast_Score=71, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6323961, Length=259, Percent_Identity=25.0965250965251, Blast_Score=71, Evalue=3e-13,
Organism=Saccharomyces cerevisiae, GI6323980, Length=255, Percent_Identity=27.843137254902, Blast_Score=68, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6319949, Length=295, Percent_Identity=26.7796610169492, Blast_Score=67, Evalue=4e-12,
Organism=Drosophila melanogaster, GI17737897, Length=349, Percent_Identity=28.6532951289398, Blast_Score=155, Evalue=3e-38,
Organism=Drosophila melanogaster, GI17137530, Length=348, Percent_Identity=28.448275862069, Blast_Score=151, Evalue=7e-37,
Organism=Drosophila melanogaster, GI17737895, Length=359, Percent_Identity=23.3983286908078, Blast_Score=73, Evalue=4e-13,
Organism=Drosophila melanogaster, GI45550770, Length=321, Percent_Identity=21.183800623053, Blast_Score=65, Evalue=5e-11,
Organism=Drosophila melanogaster, GI221457811, Length=321, Percent_Identity=21.183800623053, Blast_Score=65, Evalue=6e-11,
Organism=Drosophila melanogaster, GI45551930, Length=321, Percent_Identity=21.183800623053, Blast_Score=65, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR002328
- InterPro:   IPR011032
- InterPro:   IPR016040 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: =1.1.1.251 [H]

Molecular weight: Translated: 38547; Mature: 38547

Theoretical pI: Translated: 7.33; Mature: 7.33

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKANVLFGIGDLKYTNIPLPRLKSDEVLVKVKAAGICGSDIARVFKTGTYHFPTVIGHEF
CCCEEEEEECCCEECCCCCCCCCCCCEEEEEEECCCCCHHHHHHHHCCCEECCHHHCCHH
SGVVSDIGSSTYLSWLGKRVSVFPLKPCFKCNNCKNKEYELCSNYDYLGSRCNGGFAEYV
HHHHHHCCCHHHHHHHCCCEEEEECCCCCCCCCCCCCCHHHHCCCHHHCCCCCCCHHHHH
AVPVWNLLEIPDCVCYEEAAMLEPAAVALHALKRSGFKKGDTVVVIGPGTIGMILSQMVK
HHHHHHHHCCCCHHHHHHHHHCCHHHHHHHHHHHCCCCCCCEEEEECCCHHHHHHHHHHH
LLGASKVVLVGRTQTKLDFAKTYGVENICNSTTSDVSEWVSRNIDSSGADIVFEGTGASM
HHCCCEEEEEECCCHHHHHHHHCCHHHHHCCCHHHHHHHHHCCCCCCCCEEEEECCCCCE
SFNTSLKIVKSSGTIVALGNPIDDMTLEKDFYWKLLRKQLQIYGTWNSSFGINDNDWTQV
EECCEEEEEECCCCEEEECCCCCCCCCCHHHHHHHHHHHEEEEEEECCCCCCCCCCCEEE
LYWLENEKLDLKRLITHRLDFSQLMEGLMLMRDNSIYSNKVMLVDHE
EEEECCCCCHHHHHHHHCCCHHHHHHHHHHHCCCCEECCEEEEEECC
>Mature Secondary Structure
MKANVLFGIGDLKYTNIPLPRLKSDEVLVKVKAAGICGSDIARVFKTGTYHFPTVIGHEF
CCCEEEEEECCCEECCCCCCCCCCCCEEEEEEECCCCCHHHHHHHHCCCEECCHHHCCHH
SGVVSDIGSSTYLSWLGKRVSVFPLKPCFKCNNCKNKEYELCSNYDYLGSRCNGGFAEYV
HHHHHHCCCHHHHHHHCCCEEEEECCCCCCCCCCCCCCHHHHCCCHHHCCCCCCCHHHHH
AVPVWNLLEIPDCVCYEEAAMLEPAAVALHALKRSGFKKGDTVVVIGPGTIGMILSQMVK
HHHHHHHHCCCCHHHHHHHHHCCHHHHHHHHHHHCCCCCCCEEEEECCCHHHHHHHHHHH
LLGASKVVLVGRTQTKLDFAKTYGVENICNSTTSDVSEWVSRNIDSSGADIVFEGTGASM
HHCCCEEEEEECCCHHHHHHHHCCHHHHHCCCHHHHHHHHHCCCCCCCCEEEEECCCCCE
SFNTSLKIVKSSGTIVALGNPIDDMTLEKDFYWKLLRKQLQIYGTWNSSFGINDNDWTQV
EECCEEEEEECCCCEEEECCCCCCCCCCHHHHHHHHHHHEEEEEEECCCCCCCCCCCEEE
LYWLENEKLDLKRLITHRLDFSQLMEGLMLMRDNSIYSNKVMLVDHE
EEEECCCCCHHHHHHHHCCCHHHHHHHHHHHCCCCEECCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]