Click here to switch to the map view.

The map label for this gene is sdaA [H]

Identifier: 150007978

GI number: 150007978

Start: 1558580

End: 1559791

Strand: Reverse

Name: sdaA [H]

Synonym: BDI_1340

Alternate gene names: 150007978

Gene position: 1559791-1558580 (Counterclockwise)

Preceding gene: 150007979

Following gene: 150007977

Centisome position: 32.42

GC content: 52.39

Gene sequence:

>1212_bases
ATGGAATCAATCAAACAAATATACCGGATGGGTCATGGCCCTTCAAGTAGTCATACTATGGGGCCGATGCGTGCGGCACA
AATGTTCTTGGAACGTAACCGGGGCGCTGTTCGTTTTAACGTAACCTTATATGGTAGTCTGGCGGCTACGGGAAAAGGCC
ATATGACGGACGCGGCTATTCTTGAGGTATTACAGCCGGTCGCGAAGACAAATATTACTTGGGAACCCAAGACTTTCTTG
CCGTTCCACCCGAACGGGATGTTGTTCGAGTCGTATAATGAGAGTGGCGAGGAGCTGGATACGTGGACCGTATATAGTAT
CGGCGGGGGAACCTTGGCGAACGAGTCTTTCAATGAGTTGAGGACGGAGCAAGTATACGATATGCATACGATCAAGGAGA
TACAGGCTTGGTGTGAGAAGACTGGCCATTCCTATTGGGAATATGTCGAGCAGCACGAAGGCCCTTCTATCTGGGATTAT
CTGGCTGAGGTATGGGAAGTGATGCAGGATGCGGTTCGTCGTGGTCTGGAAGCGGAAGGCATCTTGCCGGGAGGTTTGGG
CATTCGTCGTAAGGCTTCCGATTATATGATCCGTGCGAAAGGTTATGGCAGCAGTATCAAGAGCCGGGGAATGGTGTATG
CCTATGCCTTGGCGGTGTCTGAGGAGAATGCGTGCGGTGGGAAGATCGTGACCGCTCCGACTTGTGGTTCTTGCGGTGTA
ATGCCTGCGGTCCTTTATCACTTGAAGGAGACGCGTGAGTTCCGTGATTCCCGTATATTGCGTGCGTTGGCTACGGCAGG
CTTGTTTGGAAATGTGGTGCGTACGAATGCCTCCGTATCGGGGGCAGAGGTAGGTTGCCAAGGTGAGGTTGGCGTGGCTT
GCGCTATGGCTGCCGCTGCCGCCAGTCAGTTGTTTGGTGGTACGCCCGCGCAGATCGAGTATGCCGCCGAGATGGGATTG
GAGCATCACTTGGGATTGACTTGCGATCCTGTTTGTGGCTTGGTACAAATCCCTTGTATCGAGCGAAACGCTTTTGCCGC
CGCCCGTGCACTTGACGCGAATACGTTCTCGAACTTCTCCGACGGAAAACACCGGGTAAGTTTTGATCAGGTGGTTGAGG
TGATGCGCCAGACAGGTAATGATTTGCCCAGTCTTTATAAGGAGACCTCGGAAGGTGGTTTGGCGAAGAACATGGAGAAC
TCGAATAATTAA

Upstream 100 bases:

>100_bases
CATGTGCAATGTATCGGTAATTTATGTACTTTTGTATGCGTTTTATAAACATAATATTTTCCTTAAAGTATAGAAACAAG
AAAACTTAGATCGAAGAAAG

Downstream 100 bases:

>100_bases
AAGATACTATTTGATTTACTAATAAATAATCTACTATTGATGATAAACGGAAAGAAAAGCCTGTTTTACACAGTATTGAT
GGCCGGTGCCTTGATGTCCT

Product: L-serine dehydratase

Products: NA

Alternate protein names: SDH; L-serine deaminase; L-SD [H]

Number of amino acids: Translated: 403; Mature: 403

Protein sequence:

>403_residues
MESIKQIYRMGHGPSSSHTMGPMRAAQMFLERNRGAVRFNVTLYGSLAATGKGHMTDAAILEVLQPVAKTNITWEPKTFL
PFHPNGMLFESYNESGEELDTWTVYSIGGGTLANESFNELRTEQVYDMHTIKEIQAWCEKTGHSYWEYVEQHEGPSIWDY
LAEVWEVMQDAVRRGLEAEGILPGGLGIRRKASDYMIRAKGYGSSIKSRGMVYAYALAVSEENACGGKIVTAPTCGSCGV
MPAVLYHLKETREFRDSRILRALATAGLFGNVVRTNASVSGAEVGCQGEVGVACAMAAAAASQLFGGTPAQIEYAAEMGL
EHHLGLTCDPVCGLVQIPCIERNAFAAARALDANTFSNFSDGKHRVSFDQVVEVMRQTGNDLPSLYKETSEGGLAKNMEN
SNN

Sequences:

>Translated_403_residues
MESIKQIYRMGHGPSSSHTMGPMRAAQMFLERNRGAVRFNVTLYGSLAATGKGHMTDAAILEVLQPVAKTNITWEPKTFL
PFHPNGMLFESYNESGEELDTWTVYSIGGGTLANESFNELRTEQVYDMHTIKEIQAWCEKTGHSYWEYVEQHEGPSIWDY
LAEVWEVMQDAVRRGLEAEGILPGGLGIRRKASDYMIRAKGYGSSIKSRGMVYAYALAVSEENACGGKIVTAPTCGSCGV
MPAVLYHLKETREFRDSRILRALATAGLFGNVVRTNASVSGAEVGCQGEVGVACAMAAAAASQLFGGTPAQIEYAAEMGL
EHHLGLTCDPVCGLVQIPCIERNAFAAARALDANTFSNFSDGKHRVSFDQVVEVMRQTGNDLPSLYKETSEGGLAKNMEN
SNN
>Mature_403_residues
MESIKQIYRMGHGPSSSHTMGPMRAAQMFLERNRGAVRFNVTLYGSLAATGKGHMTDAAILEVLQPVAKTNITWEPKTFL
PFHPNGMLFESYNESGEELDTWTVYSIGGGTLANESFNELRTEQVYDMHTIKEIQAWCEKTGHSYWEYVEQHEGPSIWDY
LAEVWEVMQDAVRRGLEAEGILPGGLGIRRKASDYMIRAKGYGSSIKSRGMVYAYALAVSEENACGGKIVTAPTCGSCGV
MPAVLYHLKETREFRDSRILRALATAGLFGNVVRTNASVSGAEVGCQGEVGVACAMAAAAASQLFGGTPAQIEYAAEMGL
EHHLGLTCDPVCGLVQIPCIERNAFAAARALDANTFSNFSDGKHRVSFDQVVEVMRQTGNDLPSLYKETSEGGLAKNMEN
SNN

Specific function: Anaerobic degradation of L-threonine to propionate. [C]

COG id: COG1760

COG function: function code E; L-serine deaminase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the iron-sulfur dependent L-serine dehydratase family [H]

Homologues:

Organism=Escherichia coli, GI48994925, Length=452, Percent_Identity=41.5929203539823, Blast_Score=308, Evalue=4e-85,
Organism=Escherichia coli, GI1788116, Length=455, Percent_Identity=40.6593406593407, Blast_Score=299, Evalue=2e-82,
Organism=Escherichia coli, GI1789161, Length=454, Percent_Identity=38.5462555066079, Blast_Score=291, Evalue=4e-80,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004644
- InterPro:   IPR005130
- InterPro:   IPR005131 [H]

Pfam domain/function: PF03313 SDH_alpha; PF03315 SDH_beta [H]

EC number: =4.3.1.17 [H]

Molecular weight: Translated: 43911; Mature: 43911

Theoretical pI: Translated: 5.61; Mature: 5.61

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
6.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MESIKQIYRMGHGPSSSHTMGPMRAAQMFLERNRGAVRFNVTLYGSLAATGKGHMTDAAI
CHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCCEEEEEEEEEEEEEECCCCCCHHHHH
LEVLQPVAKTNITWEPKTFLPFHPNGMLFESYNESGEELDTWTVYSIGGGTLANESFNEL
HHHHHHHHHCCCCCCCCEECCCCCCCCEEECCCCCCCCCCCEEEEEECCCCCCCCCHHHH
RTEQVYDMHTIKEIQAWCEKTGHSYWEYVEQHEGPSIWDYLAEVWEVMQDAVRRGLEAEG
HHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCC
ILPGGLGIRRKASDYMIRAKGYGSSIKSRGMVYAYALAVSEENACGGKIVTAPTCGSCGV
CCCCCCCCCCCCCCEEEEECCCCCHHHHCCEEEEEEEEECCCCCCCCEEEECCCCCCCCH
MPAVLYHLKETREFRDSRILRALATAGLFGNVVRTNASVSGAEVGCQGEVGVACAMAAAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHH
ASQLFGGTPAQIEYAAEMGLEHHLGLTCDPVCGLVQIPCIERNAFAAARALDANTFSNFS
HHHHHCCCCHHHHHHHHCCHHHCCCCCCCCCCCCEECCCCCCCHHHHHHHHCCHHCCCCC
DGKHRVSFDQVVEVMRQTGNDLPSLYKETSEGGLAKNMENSNN
CCCCCCCHHHHHHHHHHCCCCHHHHHHHHCCCCCHHCCCCCCC
>Mature Secondary Structure
MESIKQIYRMGHGPSSSHTMGPMRAAQMFLERNRGAVRFNVTLYGSLAATGKGHMTDAAI
CHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCCEEEEEEEEEEEEEECCCCCCHHHHH
LEVLQPVAKTNITWEPKTFLPFHPNGMLFESYNESGEELDTWTVYSIGGGTLANESFNEL
HHHHHHHHHCCCCCCCCEECCCCCCCCEEECCCCCCCCCCCEEEEEECCCCCCCCCHHHH
RTEQVYDMHTIKEIQAWCEKTGHSYWEYVEQHEGPSIWDYLAEVWEVMQDAVRRGLEAEG
HHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCC
ILPGGLGIRRKASDYMIRAKGYGSSIKSRGMVYAYALAVSEENACGGKIVTAPTCGSCGV
CCCCCCCCCCCCCCEEEEECCCCCHHHHCCEEEEEEEEECCCCCCCCEEEECCCCCCCCH
MPAVLYHLKETREFRDSRILRALATAGLFGNVVRTNASVSGAEVGCQGEVGVACAMAAAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHH
ASQLFGGTPAQIEYAAEMGLEHHLGLTCDPVCGLVQIPCIERNAFAAARALDANTFSNFS
HHHHHCCCCHHHHHHHHCCHHHCCCCCCCCCCCCEECCCCCCCHHHHHHHHCCHHCCCCC
DGKHRVSFDQVVEVMRQTGNDLPSLYKETSEGGLAKNMENSNN
CCCCCCCHHHHHHHHHHCCCCHHHHHHHHCCCCCHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12000953 [H]