| Definition | Parabacteroides distasonis ATCC 8503 chromosome, complete genome. |
|---|---|
| Accession | NC_009615 |
| Length | 4,811,379 |
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The map label for this gene is gyrA [H]
Identifier: 150007732
GI number: 150007732
Start: 1266140
End: 1268752
Strand: Direct
Name: gyrA [H]
Synonym: BDI_1090
Alternate gene names: 150007732
Gene position: 1266140-1268752 (Clockwise)
Preceding gene: 150007730
Following gene: 150007733
Centisome position: 26.32
GC content: 43.86
Gene sequence:
>2613_bases ATGGTTGATCAAGACAGAATTATTAAGATTAACATCGAAGAGGAAATGAAATCGGCATACATTGATTATTCAATGTCTGT CATTGTTTCACGTGCTCTTCCTGATGTTAGGGATGGCTTTAAGCCGGTTCACCGCCGTATTTTATTTGGAATGAATGAAC TGGGTAACACATCCGACAAACCTTATAAAAAATCTGCGAGAATAGTTGGTGAAGTTTTAGGTAAATATCATCCACATGGC GACTCGTCTGTATATTTCGCCATGGTTCGTATGGCCCAGACATGGTCTATGCGTTATCCGTTAGTAGACGGACAAGGTAA CTTCGGTTCAGTGGACGGTGATAGTCCTGCCGCTATGCGTTATACAGAGGCACGACTGAGTAAACTCGCCGAAGAAATGC TCCGGGATATCGATAAGGACACGGTAGATTTCCAGCTTAACTTCGATGATACGTTGAAGGAGCCGACCGTATTACCGACT CGTGTTCCTAACTTACTTGTAAATGGTGGATCGGGTATCGCCGTTGGTATGGCTACGAATATGCCAACTCATAACTTGAG CGAGGTATTAGATGGTTGTATCGCTTATATCGATGCCAAGGGAGATATCGAGGTAGAGGGCTTAATGCAATATATCAAGG CTCCGGACTTCCCTACAGGCGCTACAATTTATGGCTACGCAGGCGTGAAAGACGCTTTCGAGACGGGTAGGGGACGTATC ATCCTTCGCGGTAAAGCCGAGATTGAGGTGGAGAATAATCATGAGAAGATTATTATTACCGAGATTCCTTATTTGGTAAA TAAGGCTGAGTTGATCAAGTATATCGCTGACCTGGTAAACGAGAAGCGTATCGATGGCATTTCCAATGTCAATGATGAGT CCGACCGTAGCGGTATGCGTATCGTAGTTGACGTGAAACGTGATGCGAACTCGAGTGTCGTACTGAATAAATTGTATAAG CTTACGGCTCTGCAATCCTCATTCAGCGTTAATAATATCGCTTTGGTGAACGGCCGTCCGAGGTTGCTTAACTTAAAAGA CTTAATCAAGGCGTTTGTTGAGCACCGTCATGAGGTCGTTATCCGGCGTACAAAATATGAATTGAGGAAAGCGGAAGAGA GAGCCCATATATTGGAAGGCTTGATCATCGCTTCCGATAATATAGACGAGGTAATCGCGATTATCAAGTCTTCCAAGAGC CCGCAAGAGGCTATCGAGCGTTTGATCGAACGTTTCTCTTTATCTGAGCTTCAAGCACGTGCGATTGTAGAGATGAGACT TCGTCAGTTGACAGGTCTGGAACAAGACAAATTGCGTGCGGAATATGAGGAGATCGAGAAGTTGATCGCTTATTTGAATG AGATTCTGGAGAATGAGGACCTTTGTATGAAGGTTATCAAAGATGAATTATTGGAAATCAAGGATAAATTTGGCGACGAA CGTAAGACGGATATCGTTTACGCCTCTGAGGAATTAAATCCGGAGGATTTCTATGCGGATGATGAGATGATCATTACCGT ATCTCATATGGGATATATCAAACGTACCCCGTTGAGTGAGTTCCGTGCGCAAGGCCGTGGTGGTGTAGGAGCGAAGGGTT CCGAGACTAGAGACGAGGATTTCGTTGAGTATATCTATCCGGCATCCATGCACGCGACCTTATTATTCTTCACGGCAAAA GGTAAATGTTATTGGTTGAAGGTATTCGAGATTCCGGAAGGGGCTAAGAACGCTAAAGGACGTGCGATCCAGAATCTTCT GAATATCGAGCCGGATGATAAGGTACAAGCTTTTATACGTGTTAAGAAATTAACCACCGATACGGAATTCATTAATTCTC ATTACCTATTATTCTGTACGAAGAAAGGTGTGATCAAAAAGACTTTGTTGGAGGCCTATTCCCGTCCTCGTCAAAACGGT GTGAACGCTATTACATTGCGTGAAGACGATGGCTTGATCCAAGTATGTATGACGAATGGTAACAACGAGGTGATCATAGC GAACCGTAACGGCCGGGCGATCCGTTTCCATGAAAGCGCGGTACGTGTAATGGGCCGTACGGCTTCCGGAGTGAAAGGTA TGACTTTGGACGAGGATAATACCGATGAAGTCGTTGGTATGATCTGTATCAAGGACAAGGAAAAAGAGACCGTACTCGTC GTATCAGAGCAGGGATATGGAAAACGTTCCTCTATCGAGGATTATCGTATAACGAATCGTGGCGGTAAAGGCGTAAAAAC CATTAATATCACGGAGAAGACCGGTAAATTAGTTGCCATCAAGAATGTTACGGACGAGAACGATTTAATGATTATCAATA AGTCGGGTATCGCTATCCGTATGAAAGTGGCCGATTTAAACGTAATAGGACGTGCTACTCAAGGTGTTCGTTTGATTAAT CTAGAAAAGCGCAACGACGAAATCGCTTCTGTATGTAAAGTATTGTCTGAGAGTGAAGAGGAGATAGCCGAGCAAAAAGC GGAACAAGAAGCCAGACAAGAGAATGAGGGAAGAGAGTTCAGTGAGAATCAAGCTAGTCTAGGTACTGATGTTGATCTAC CGGAATCAGAGGAGGATAACGAACAAAATGATAACGAAGAAATAACTGAATAA
Upstream 100 bases:
>100_bases TCAAAATTTCAAGACAAATTCTTTCGTAGTATACGGAAAAACCTTACCTTAGTGCAATTTTTCAGAGGTGAGATATTGAG TGTAATTAATATAAAACTAA
Downstream 100 bases:
>100_bases TTTTAAACAAATAGAAATATTAATCTCAAAATTACTATCACAATGAAACGAGTATTATTAACAGTGGCACTATGTGTCGC AGCATCGGTCTCTTTTGCAC
Product: DNA gyrase subunit A
Products: NA
Alternate protein names: NA
Number of amino acids: Translated: 870; Mature: 870
Protein sequence:
>870_residues MVDQDRIIKINIEEEMKSAYIDYSMSVIVSRALPDVRDGFKPVHRRILFGMNELGNTSDKPYKKSARIVGEVLGKYHPHG DSSVYFAMVRMAQTWSMRYPLVDGQGNFGSVDGDSPAAMRYTEARLSKLAEEMLRDIDKDTVDFQLNFDDTLKEPTVLPT RVPNLLVNGGSGIAVGMATNMPTHNLSEVLDGCIAYIDAKGDIEVEGLMQYIKAPDFPTGATIYGYAGVKDAFETGRGRI ILRGKAEIEVENNHEKIIITEIPYLVNKAELIKYIADLVNEKRIDGISNVNDESDRSGMRIVVDVKRDANSSVVLNKLYK LTALQSSFSVNNIALVNGRPRLLNLKDLIKAFVEHRHEVVIRRTKYELRKAEERAHILEGLIIASDNIDEVIAIIKSSKS PQEAIERLIERFSLSELQARAIVEMRLRQLTGLEQDKLRAEYEEIEKLIAYLNEILENEDLCMKVIKDELLEIKDKFGDE RKTDIVYASEELNPEDFYADDEMIITVSHMGYIKRTPLSEFRAQGRGGVGAKGSETRDEDFVEYIYPASMHATLLFFTAK GKCYWLKVFEIPEGAKNAKGRAIQNLLNIEPDDKVQAFIRVKKLTTDTEFINSHYLLFCTKKGVIKKTLLEAYSRPRQNG VNAITLREDDGLIQVCMTNGNNEVIIANRNGRAIRFHESAVRVMGRTASGVKGMTLDEDNTDEVVGMICIKDKEKETVLV VSEQGYGKRSSIEDYRITNRGGKGVKTINITEKTGKLVAIKNVTDENDLMIINKSGIAIRMKVADLNVIGRATQGVRLIN LEKRNDEIASVCKVLSESEEEIAEQKAEQEARQENEGREFSENQASLGTDVDLPESEEDNEQNDNEEITE
Sequences:
>Translated_870_residues MVDQDRIIKINIEEEMKSAYIDYSMSVIVSRALPDVRDGFKPVHRRILFGMNELGNTSDKPYKKSARIVGEVLGKYHPHG DSSVYFAMVRMAQTWSMRYPLVDGQGNFGSVDGDSPAAMRYTEARLSKLAEEMLRDIDKDTVDFQLNFDDTLKEPTVLPT RVPNLLVNGGSGIAVGMATNMPTHNLSEVLDGCIAYIDAKGDIEVEGLMQYIKAPDFPTGATIYGYAGVKDAFETGRGRI ILRGKAEIEVENNHEKIIITEIPYLVNKAELIKYIADLVNEKRIDGISNVNDESDRSGMRIVVDVKRDANSSVVLNKLYK LTALQSSFSVNNIALVNGRPRLLNLKDLIKAFVEHRHEVVIRRTKYELRKAEERAHILEGLIIASDNIDEVIAIIKSSKS PQEAIERLIERFSLSELQARAIVEMRLRQLTGLEQDKLRAEYEEIEKLIAYLNEILENEDLCMKVIKDELLEIKDKFGDE RKTDIVYASEELNPEDFYADDEMIITVSHMGYIKRTPLSEFRAQGRGGVGAKGSETRDEDFVEYIYPASMHATLLFFTAK GKCYWLKVFEIPEGAKNAKGRAIQNLLNIEPDDKVQAFIRVKKLTTDTEFINSHYLLFCTKKGVIKKTLLEAYSRPRQNG VNAITLREDDGLIQVCMTNGNNEVIIANRNGRAIRFHESAVRVMGRTASGVKGMTLDEDNTDEVVGMICIKDKEKETVLV VSEQGYGKRSSIEDYRITNRGGKGVKTINITEKTGKLVAIKNVTDENDLMIINKSGIAIRMKVADLNVIGRATQGVRLIN LEKRNDEIASVCKVLSESEEEIAEQKAEQEARQENEGREFSENQASLGTDVDLPESEEDNEQNDNEEITE >Mature_870_residues MVDQDRIIKINIEEEMKSAYIDYSMSVIVSRALPDVRDGFKPVHRRILFGMNELGNTSDKPYKKSARIVGEVLGKYHPHG DSSVYFAMVRMAQTWSMRYPLVDGQGNFGSVDGDSPAAMRYTEARLSKLAEEMLRDIDKDTVDFQLNFDDTLKEPTVLPT RVPNLLVNGGSGIAVGMATNMPTHNLSEVLDGCIAYIDAKGDIEVEGLMQYIKAPDFPTGATIYGYAGVKDAFETGRGRI ILRGKAEIEVENNHEKIIITEIPYLVNKAELIKYIADLVNEKRIDGISNVNDESDRSGMRIVVDVKRDANSSVVLNKLYK LTALQSSFSVNNIALVNGRPRLLNLKDLIKAFVEHRHEVVIRRTKYELRKAEERAHILEGLIIASDNIDEVIAIIKSSKS PQEAIERLIERFSLSELQARAIVEMRLRQLTGLEQDKLRAEYEEIEKLIAYLNEILENEDLCMKVIKDELLEIKDKFGDE RKTDIVYASEELNPEDFYADDEMIITVSHMGYIKRTPLSEFRAQGRGGVGAKGSETRDEDFVEYIYPASMHATLLFFTAK GKCYWLKVFEIPEGAKNAKGRAIQNLLNIEPDDKVQAFIRVKKLTTDTEFINSHYLLFCTKKGVIKKTLLEAYSRPRQNG VNAITLREDDGLIQVCMTNGNNEVIIANRNGRAIRFHESAVRVMGRTASGVKGMTLDEDNTDEVVGMICIKDKEKETVLV VSEQGYGKRSSIEDYRITNRGGKGVKTINITEKTGKLVAIKNVTDENDLMIINKSGIAIRMKVADLNVIGRATQGVRLIN LEKRNDEIASVCKVLSESEEEIAEQKAEQEARQENEGREFSENQASLGTDVDLPESEEDNEQNDNEEITE
Specific function: DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings [H]
COG id: COG0188
COG function: function code L; Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), A subunit
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the topoisomerase gyrA/parC subunit family [H]
Homologues:
Organism=Homo sapiens, GI19913408, Length=442, Percent_Identity=24.2081447963801, Blast_Score=81, Evalue=4e-15, Organism=Homo sapiens, GI19913406, Length=202, Percent_Identity=29.7029702970297, Blast_Score=72, Evalue=2e-12, Organism=Escherichia coli, GI1788562, Length=829, Percent_Identity=48.7334137515078, Blast_Score=802, Evalue=0.0, Organism=Escherichia coli, GI1789396, Length=680, Percent_Identity=35.2941176470588, Blast_Score=390, Evalue=1e-109, Organism=Caenorhabditis elegans, GI212645845, Length=197, Percent_Identity=29.9492385786802, Blast_Score=78, Evalue=2e-14, Organism=Caenorhabditis elegans, GI17535065, Length=166, Percent_Identity=31.9277108433735, Blast_Score=72, Evalue=1e-12, Organism=Saccharomyces cerevisiae, GI6324241, Length=237, Percent_Identity=28.2700421940928, Blast_Score=74, Evalue=9e-14, Organism=Drosophila melanogaster, GI17136538, Length=167, Percent_Identity=30.5389221556886, Blast_Score=70, Evalue=4e-12,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR020899 - InterPro: IPR005743 - InterPro: IPR006691 - InterPro: IPR010235 - InterPro: IPR002205 - InterPro: IPR013758 - InterPro: IPR013757 - InterPro: IPR013760 [H]
Pfam domain/function: PF03989 DNA_gyraseA_C; PF00521 DNA_topoisoIV; PF08780 NTase_sub_bind [H]
EC number: =5.99.1.3 [H]
Molecular weight: Translated: 97940; Mature: 97940
Theoretical pI: Translated: 4.93; Mature: 4.93
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.8 %Cys (Translated Protein) 2.8 %Met (Translated Protein) 3.6 %Cys+Met (Translated Protein) 0.8 %Cys (Mature Protein) 2.8 %Met (Mature Protein) 3.6 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MVDQDRIIKINIEEEMKSAYIDYSMSVIVSRALPDVRDGFKPVHRRILFGMNELGNTSDK CCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCHHHHCCCCCC PYKKSARIVGEVLGKYHPHGDSSVYFAMVRMAQTWSMRYPLVDGQGNFGSVDGDSPAAMR CHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCEECCCCCCCCCCCCCCHHHH YTEARLSKLAEEMLRDIDKDTVDFQLNFDDTLKEPTVLPTRVPNLLVNGGSGIAVGMATN HHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCCCCCEEEECCCEEEEEEECC MPTHNLSEVLDGCIAYIDAKGDIEVEGLMQYIKAPDFPTGATIYGYAGVKDAFETGRGRI CCCCCHHHHHHHHHEEECCCCCEEHHHHHHHHHCCCCCCCCEEEECCCCHHHHHCCCCEE ILRGKAEIEVENNHEKIIITEIPYLVNKAELIKYIADLVNEKRIDGISNVNDESDRSGMR EEECCEEEEEECCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCE IVVDVKRDANSSVVLNKLYKLTALQSSFSVNNIALVNGRPRLLNLKDLIKAFVEHRHEVV EEEEECCCCCCHHHHHHHHHHHHHHCCCCCCCEEEECCCCCEECHHHHHHHHHHHHHHEE IRRTKYELRKAEERAHILEGLIIASDNIDEVIAIIKSSKSPQEAIERLIERFSLSELQAR HHHHHHHHHHHHHHHHHHHCEEEECCCHHHHHHHHHCCCCHHHHHHHHHHHHCHHHHHHH AIVEMRLRQLTGLEQDKLRAEYEEIEKLIAYLNEILENEDLCMKVIKDELLEIKDKFGDE HHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCC RKTDIVYASEELNPEDFYADDEMIITVSHMGYIKRTPLSEFRAQGRGGVGAKGSETRDED CCCEEEEECCCCCHHHCCCCCCEEEEEECCCCEECCCHHHHHHCCCCCCCCCCCCCCCHH FVEYIYPASMHATLLFFTAKGKCYWLKVFEIPEGAKNAKGRAIQNLLNIEPDDKVQAFIR HHHHHCCCCCEEEEEEEEECCCEEEEEEEECCCCCCCCCCHHHHHHHCCCCCHHHHHHHH VKKLTTDTEFINSHYLLFCTKKGVIKKTLLEAYSRPRQNGVNAITLREDDGLIQVCMTNG HHHHCCCHHHHCCCEEEEEECCCHHHHHHHHHHCCHHHCCCCEEEEECCCCEEEEEEECC NNEVIIANRNGRAIRFHESAVRVMGRTASGVKGMTLDEDNTDEVVGMICIKDKEKETVLV CCEEEEECCCCCEEEEEHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEEEEECCCCCEEEE VSEQGYGKRSSIEDYRITNRGGKGVKTINITEKTGKLVAIKNVTDENDLMIINKSGIAIR EECCCCCCCCCCCCEEEECCCCCCEEEEEEECCCCCEEEEECCCCCCCEEEEECCCCEEE MKVADLNVIGRATQGVRLINLEKRNDEIASVCKVLSESEEEIAEQKAEQEARQENEGREF EEEECEEEECCCCCCEEEEEEECCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCC SENQASLGTDVDLPESEEDNEQNDNEEITE CCCHHCCCCCCCCCCCCCCCCCCCCCCCCC >Mature Secondary Structure MVDQDRIIKINIEEEMKSAYIDYSMSVIVSRALPDVRDGFKPVHRRILFGMNELGNTSDK CCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCHHHHCCCCCC PYKKSARIVGEVLGKYHPHGDSSVYFAMVRMAQTWSMRYPLVDGQGNFGSVDGDSPAAMR CHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCEECCCCCCCCCCCCCCHHHH YTEARLSKLAEEMLRDIDKDTVDFQLNFDDTLKEPTVLPTRVPNLLVNGGSGIAVGMATN HHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCCCCCEEEECCCEEEEEEECC MPTHNLSEVLDGCIAYIDAKGDIEVEGLMQYIKAPDFPTGATIYGYAGVKDAFETGRGRI CCCCCHHHHHHHHHEEECCCCCEEHHHHHHHHHCCCCCCCCEEEECCCCHHHHHCCCCEE ILRGKAEIEVENNHEKIIITEIPYLVNKAELIKYIADLVNEKRIDGISNVNDESDRSGMR EEECCEEEEEECCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCE IVVDVKRDANSSVVLNKLYKLTALQSSFSVNNIALVNGRPRLLNLKDLIKAFVEHRHEVV EEEEECCCCCCHHHHHHHHHHHHHHCCCCCCCEEEECCCCCEECHHHHHHHHHHHHHHEE IRRTKYELRKAEERAHILEGLIIASDNIDEVIAIIKSSKSPQEAIERLIERFSLSELQAR HHHHHHHHHHHHHHHHHHHCEEEECCCHHHHHHHHHCCCCHHHHHHHHHHHHCHHHHHHH AIVEMRLRQLTGLEQDKLRAEYEEIEKLIAYLNEILENEDLCMKVIKDELLEIKDKFGDE HHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCC RKTDIVYASEELNPEDFYADDEMIITVSHMGYIKRTPLSEFRAQGRGGVGAKGSETRDED CCCEEEEECCCCCHHHCCCCCCEEEEEECCCCEECCCHHHHHHCCCCCCCCCCCCCCCHH FVEYIYPASMHATLLFFTAKGKCYWLKVFEIPEGAKNAKGRAIQNLLNIEPDDKVQAFIR HHHHHCCCCCEEEEEEEEECCCEEEEEEEECCCCCCCCCCHHHHHHHCCCCCHHHHHHHH VKKLTTDTEFINSHYLLFCTKKGVIKKTLLEAYSRPRQNGVNAITLREDDGLIQVCMTNG HHHHCCCHHHHCCCEEEEEECCCHHHHHHHHHHCCHHHCCCCEEEEECCCCEEEEEEECC NNEVIIANRNGRAIRFHESAVRVMGRTASGVKGMTLDEDNTDEVVGMICIKDKEKETVLV CCEEEEECCCCCEEEEEHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEEEEECCCCCEEEE VSEQGYGKRSSIEDYRITNRGGKGVKTINITEKTGKLVAIKNVTDENDLMIINKSGIAIR EECCCCCCCCCCCCEEEECCCCCCEEEEEEECCCCCEEEEECCCCCCCEEEEECCCCEEE MKVADLNVIGRATQGVRLINLEKRNDEIASVCKVLSESEEEIAEQKAEQEARQENEGREF EEEECEEEECCCCCCEEEEEEECCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCC SENQASLGTDVDLPESEEDNEQNDNEEITE CCCHHCCCCCCCCCCCCCCCCCCCCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 10427704; 11058132 [H]