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The map label for this gene is mtaD [H]

Identifier: 150007729

GI number: 150007729

Start: 1260793

End: 1262049

Strand: Direct

Name: mtaD [H]

Synonym: BDI_1084

Alternate gene names: 150007729

Gene position: 1260793-1262049 (Clockwise)

Preceding gene: 150007728

Following gene: 150007730

Centisome position: 26.2

GC content: 47.33

Gene sequence:

>1257_bases
ATGAGTATATTAATAAAGAATGTCCTGTTTAACGATAAAACGATTGATATCTATATCGAAGGAAAAGAGATCAAGCAAAT
AGGAGCGGGGCTGTCCTTTCCTGCCGATAAGATACTGGATGGTAGCCGTAAAGCCGTCATTCCCGGTTTCGTGAACGCTC
ATACGCATGCTGCCATGACTTTGTTCCGCGGCTTTGGCGATGATATGCCGCTTATGCCGTGGCTTGAGCAAAAGATCTGG
CCGAATGAGGCGAAAATGACCCGTGAGGATGTATATTGGGGAGCGAAATTAGCGTGTTTGGAAATGATAAAAAGTGGCAC
GACCACTTTCTTCGACATGTATCAACGCCCTCGTGTCACGGCCGATGTGACGGAAGAGATGGGATTGCGAGGTATCATAG
CCGGCGTTTGCTTCGATGGTTTTGATAAAGAAGAGGCGGAGAAATGCAAACGCCATAACGAACGACTGATCCAAGATGTG
GATAACTACAGCAAACGGGTTCGCTTCTCGATCGGGCCACACGCTATCTATACCGTTTCCGGTGAGCTTCTGAAATGGGC
GCATCAGTTCGCCATGGAACACCAAATCCCTATCCATCTGCATCTGGCAGAGACAGAGGGGGAAGTGAAAGACTCTCTCG
ATAGATTCGGACTCACTCCCGTACGTTATTTATATGAGTTAGGTGTGCTTTCTCCACGTTTGATCATCGCTCATGGAATT
TACATCGATGATGACGAGCTTCGTATGTTGGCCGATCACGAGGTGAAAGTCGTACATAACCCGGCCTCAAACATGAAACT
GGCTTCCGGCATGCATTTTAAGTTCAAGGAAATGCGCCAATTGGGTATTACCGTGGGATTGGGAACGGACGGTTGTTCCT
CTTCCAATAACTTGGATATGATCGAGGCGATGAAGCTGGCTTCCCTGTTAGGAAAAGCTTGGCGAAAGGATCCCGAAGCC
TTGACCGCAAATGAGATGCTGCAAGCCGCTACTGCGGAAGGAGCCGTTATGTTCGGTTTAAAAGCCGGGCAGATCAAGGA
AGGGTATTTAGCCGATCTATGTTTGATAGATCTCAACACCCCCGCTTTTACCCCAAACTTCAATTTCGTCTCAAATCTTG
TATACGCCGCCAACGGCAGTTGCGTGGATACCGTTATCTGTGATGGTAAAATATTGATGGAGAATAAGAAGGTACCGGGA
GAGGACGAGATTATGGAGAAAGCGGCAGAGATAGCTTATAACTTGATGAAACGTTAA

Upstream 100 bases:

>100_bases
CGATCCATTCGCCCAACGAGAGTCAGGAGTTGGATATCTTCTTCAAGGGAATCGAGTCGGTAGCGGAATTCTACCGTTTA
TATAAATAAGAAGGAAGAAG

Downstream 100 bases:

>100_bases
ATTGATTAAATATGGAAATGATTAAAACCGAACAATATCGGGAAGCGGCCGCCTATTTAGCTAGCCGGATCGAAGGTAAC
CCGGAGACCGCCATTATCCT

Product: chlorohydrolase family protein

Products: NA

Alternate protein names: MTA/SAH deaminase [H]

Number of amino acids: Translated: 418; Mature: 417

Protein sequence:

>418_residues
MSILIKNVLFNDKTIDIYIEGKEIKQIGAGLSFPADKILDGSRKAVIPGFVNAHTHAAMTLFRGFGDDMPLMPWLEQKIW
PNEAKMTREDVYWGAKLACLEMIKSGTTTFFDMYQRPRVTADVTEEMGLRGIIAGVCFDGFDKEEAEKCKRHNERLIQDV
DNYSKRVRFSIGPHAIYTVSGELLKWAHQFAMEHQIPIHLHLAETEGEVKDSLDRFGLTPVRYLYELGVLSPRLIIAHGI
YIDDDELRMLADHEVKVVHNPASNMKLASGMHFKFKEMRQLGITVGLGTDGCSSSNNLDMIEAMKLASLLGKAWRKDPEA
LTANEMLQAATAEGAVMFGLKAGQIKEGYLADLCLIDLNTPAFTPNFNFVSNLVYAANGSCVDTVICDGKILMENKKVPG
EDEIMEKAAEIAYNLMKR

Sequences:

>Translated_418_residues
MSILIKNVLFNDKTIDIYIEGKEIKQIGAGLSFPADKILDGSRKAVIPGFVNAHTHAAMTLFRGFGDDMPLMPWLEQKIW
PNEAKMTREDVYWGAKLACLEMIKSGTTTFFDMYQRPRVTADVTEEMGLRGIIAGVCFDGFDKEEAEKCKRHNERLIQDV
DNYSKRVRFSIGPHAIYTVSGELLKWAHQFAMEHQIPIHLHLAETEGEVKDSLDRFGLTPVRYLYELGVLSPRLIIAHGI
YIDDDELRMLADHEVKVVHNPASNMKLASGMHFKFKEMRQLGITVGLGTDGCSSSNNLDMIEAMKLASLLGKAWRKDPEA
LTANEMLQAATAEGAVMFGLKAGQIKEGYLADLCLIDLNTPAFTPNFNFVSNLVYAANGSCVDTVICDGKILMENKKVPG
EDEIMEKAAEIAYNLMKR
>Mature_417_residues
SILIKNVLFNDKTIDIYIEGKEIKQIGAGLSFPADKILDGSRKAVIPGFVNAHTHAAMTLFRGFGDDMPLMPWLEQKIWP
NEAKMTREDVYWGAKLACLEMIKSGTTTFFDMYQRPRVTADVTEEMGLRGIIAGVCFDGFDKEEAEKCKRHNERLIQDVD
NYSKRVRFSIGPHAIYTVSGELLKWAHQFAMEHQIPIHLHLAETEGEVKDSLDRFGLTPVRYLYELGVLSPRLIIAHGIY
IDDDELRMLADHEVKVVHNPASNMKLASGMHFKFKEMRQLGITVGLGTDGCSSSNNLDMIEAMKLASLLGKAWRKDPEAL
TANEMLQAATAEGAVMFGLKAGQIKEGYLADLCLIDLNTPAFTPNFNFVSNLVYAANGSCVDTVICDGKILMENKKVPGE
DEIMEKAAEIAYNLMKR

Specific function: Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine [H]

COG id: COG0402

COG function: function code FR; Cytosine deaminase and related metal-dependent hydrolases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the MTA/SAH deaminase family [H]

Homologues:

Organism=Homo sapiens, GI4758426, Length=332, Percent_Identity=27.710843373494, Blast_Score=107, Evalue=2e-23,
Organism=Escherichia coli, GI87082177, Length=431, Percent_Identity=26.4501160092807, Blast_Score=129, Evalue=5e-31,
Organism=Escherichia coli, GI1789249, Length=373, Percent_Identity=26.2734584450402, Blast_Score=87, Evalue=3e-18,
Organism=Saccharomyces cerevisiae, GI6319963, Length=340, Percent_Identity=26.1764705882353, Blast_Score=89, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24643849, Length=272, Percent_Identity=29.7794117647059, Blast_Score=100, Evalue=2e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006680
- InterPro:   IPR011059 [H]

Pfam domain/function: PF01979 Amidohydro_1 [H]

EC number: =3.5.4.28 [H]

Molecular weight: Translated: 46718; Mature: 46586

Theoretical pI: Translated: 5.79; Mature: 5.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
4.8 %Met     (Translated Protein)
6.5 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
4.6 %Met     (Mature Protein)
6.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSILIKNVLFNDKTIDIYIEGKEIKQIGAGLSFPADKILDGSRKAVIPGFVNAHTHAAMT
CCEEEEEHHCCCCEEEEEECCHHHHHHCCCCCCCHHHHCCCCCCEECCCHHCHHHHHHHH
LFRGFGDDMPLMPWLEQKIWPNEAKMTREDVYWGAKLACLEMIKSGTTTFFDMYQRPRVT
HHHHCCCCCCCCHHHHHHCCCCHHHHHHHHHHCCHHHHHHHHHHCCCHHHHHHHHCCCCC
ADVTEEMGLRGIIAGVCFDGFDKEEAEKCKRHNERLIQDVDNYSKRVRFSIGPHAIYTVS
CHHHHHCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCEEEEEC
GELLKWAHQFAMEHQIPIHLHLAETEGEVKDSLDRFGLTPVRYLYELGVLSPRLIIAHGI
HHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHCCCHHHHHHHHCCCCCCEEEEECC
YIDDDELRMLADHEVKVVHNPASNMKLASGMHFKFKEMRQLGITVGLGTDGCSSSNNLDM
EECCCCCEEEECCCEEEEECCCCCCEECCCCCHHHHHHHHCCCEEEECCCCCCCCCCCHH
IEAMKLASLLGKAWRKDPEALTANEMLQAATAEGAVMFGLKAGQIKEGYLADLCLIDLNT
HHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCEEEEECCCCCCCCCCEEEEEEEECCC
PAFTPNFNFVSNLVYAANGSCVDTVICDGKILMENKKVPGEDEIMEKAAEIAYNLMKR
CCCCCCHHHHHHHHEECCCCEEEEEEECCEEEEECCCCCCHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SILIKNVLFNDKTIDIYIEGKEIKQIGAGLSFPADKILDGSRKAVIPGFVNAHTHAAMT
CEEEEEHHCCCCEEEEEECCHHHHHHCCCCCCCHHHHCCCCCCEECCCHHCHHHHHHHH
LFRGFGDDMPLMPWLEQKIWPNEAKMTREDVYWGAKLACLEMIKSGTTTFFDMYQRPRVT
HHHHCCCCCCCCHHHHHHCCCCHHHHHHHHHHCCHHHHHHHHHHCCCHHHHHHHHCCCCC
ADVTEEMGLRGIIAGVCFDGFDKEEAEKCKRHNERLIQDVDNYSKRVRFSIGPHAIYTVS
CHHHHHCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCEEEEEC
GELLKWAHQFAMEHQIPIHLHLAETEGEVKDSLDRFGLTPVRYLYELGVLSPRLIIAHGI
HHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHCCCHHHHHHHHCCCCCCEEEEECC
YIDDDELRMLADHEVKVVHNPASNMKLASGMHFKFKEMRQLGITVGLGTDGCSSSNNLDM
EECCCCCEEEECCCEEEEECCCCCCEECCCCCHHHHHHHHCCCEEEECCCCCCCCCCCHH
IEAMKLASLLGKAWRKDPEALTANEMLQAATAEGAVMFGLKAGQIKEGYLADLCLIDLNT
HHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCEEEEECCCCCCCCCCEEEEEEEECCC
PAFTPNFNFVSNLVYAANGSCVDTVICDGKILMENKKVPGEDEIMEKAAEIAYNLMKR
CCCCCCHHHHHHHHEECCCCEEEEEEECCEEEEECCCCCCHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA