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The map label for this gene is yfnA [H]

Identifier: 150007724

GI number: 150007724

Start: 1255170

End: 1256828

Strand: Reverse

Name: yfnA [H]

Synonym: BDI_1079

Alternate gene names: 150007724

Gene position: 1256828-1255170 (Counterclockwise)

Preceding gene: 150007726

Following gene: 150007722

Centisome position: 26.12

GC content: 48.7

Gene sequence:

>1659_bases
ATGGGTTTATTTATTAAGAAGCCTTTAGCGGATTTGATGACCGAGGCAAATGATTCGGGCAGTAAATCGCTGAAGCGTAT
CCTTGGCCCGTGGAGTTTGATTGCCTTAGGTGTCGGTGTTATTATCGGTGCCGGATTGTTCTCCATTACGGGTGCGGTGG
CCGCCGGGTATACGGGGCCTGCCATTACTTTATCTTTCGCTATCGCCGCCTTGGGCTGTTGTTTCGCCGGGTTATGTTAC
GCCGAGTTCGCATCCATGATCCCGGTGGCAGGTAGCGCATATACCTACTCGTATGCCACGATGGGTGAGTTGGTCGCTTG
GATTATCGGTTGGGATTTGGTGCTCGAGTACTGCGTGGCCGCTACGACCGTTAGCATAAGTTGGAGTCGGTATTTGGTCG
TTTTTCTGGAAGGATTCGGAGTACATTTACCGCAAGCCTTGACAGCTTGCCCTTGGGATGGCGGTATCGTGAATATCCCG
GCTTTCGTGATCGTGGTGTTAATGAGTATCTTGTTGATACGAGGAACGGAAGGCAGTTCTATCTTTAATGGGATCATCGT
ATTCTTGAAAGTCTCCGTAGTCTTGGTGTTCGTAGTCTTGGGATGGAAATATATCCGTATGGAGAATTATACGCCTTATA
TCCCCACTAATACAGGGACTCTAGGCGAGTTCGGATTTTCCGGTATCCTACGAGGGGCGGCTATCGTATTCTTTGCTTTC
CTCGGTTTCGACGCTGTAAGTACGGCAGCGCAGGAAACCAAGAACCCGAAACGGGATATGCCGATCGGGATCTTGATGTC
ATTGGTGGTTTGTACTATATTATATATGCTGTTTGCCCACGTGATGACCGGAGTCGTACATTACTCCGCTTTTGCTGGCC
AGAATGGAATCGCTCCTGTGGCAATAGCTATCGATCATATGGGACAAATGGATGCTTCTGGTGTGATTCGTCCGGATTAC
CCTTGGATGAATCGGGCGATCGTAATAGCTATTTTACTGGGGTATTGCTCGGTTATCATGGTAACGTTATTAGGACAGAG
CCGTGTATTCTTGAGTATGAGCCGGGATGGGCTGCTCCCTCCCCTATTTTCCCATATCCATGAGAAATTCCGCACGCCGG
CACGAAGTAATTTCCTGTTTATGTTATTGGTCGGTACATTGGCTGCTTTCGTTCCGGCGAGCGTAGCGGGCGAGATGTGT
AGTATCGGGACTTTGTTCGCTTTTACGCTAGTTTGCGCCGGGGTATTGATTGTCCGTAAGACAATGCCGGACGCTCCCCG
GTCTTTCAAGACCCCGTTGGTTCCGTTCGTGCCTATCGCCGGTATCATAACTTGTCTGGTGATGATGCTTTTTCTCCCGG
CTGATACATGGATTCGTTTGGTATTATGGATGTTAATCGGTCTGGATATATATGTCTGCTATGGAATCAAACATAGCAAA
CTGGAACATATGCAGAAACATCGCTCGGGACAGACCACATTGGATATGATCGGTATTACCCTATCCGTGCTTTGCGTGAT
TACGGGGCTTTGGCACCAGCAAACCGTGGGATGGGGCGAGAGCAAAGTCTTATTGATTATCTCATTCGTATTCGCTTTTA
CGCATCTAGCTTTCTATCTTTACAGACTCGGGAAGCAGTTTACGAGCCTTACCCGTTAG

Upstream 100 bases:

>100_bases
TTTATTTTCTTGTTTGTTTCTGTCCTTGCTTTTACTTTTCGGCAAACATAATAAAAATTCCTACCTTTGCGCCCAATTAC
TAATTTTTTAATCTATACAG

Downstream 100 bases:

>100_bases
CGATTCAGCACGATTATGTCTCGATGGCTCACGCGACTAGTCCCGATGGTCAACGCCATTAGTGGTGAAGGCTTATGCGA
GTAGTCGCGTTGACCTTCAC

Product: cationic amino acid transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 552; Mature: 551

Protein sequence:

>552_residues
MGLFIKKPLADLMTEANDSGSKSLKRILGPWSLIALGVGVIIGAGLFSITGAVAAGYTGPAITLSFAIAALGCCFAGLCY
AEFASMIPVAGSAYTYSYATMGELVAWIIGWDLVLEYCVAATTVSISWSRYLVVFLEGFGVHLPQALTACPWDGGIVNIP
AFVIVVLMSILLIRGTEGSSIFNGIIVFLKVSVVLVFVVLGWKYIRMENYTPYIPTNTGTLGEFGFSGILRGAAIVFFAF
LGFDAVSTAAQETKNPKRDMPIGILMSLVVCTILYMLFAHVMTGVVHYSAFAGQNGIAPVAIAIDHMGQMDASGVIRPDY
PWMNRAIVIAILLGYCSVIMVTLLGQSRVFLSMSRDGLLPPLFSHIHEKFRTPARSNFLFMLLVGTLAAFVPASVAGEMC
SIGTLFAFTLVCAGVLIVRKTMPDAPRSFKTPLVPFVPIAGIITCLVMMLFLPADTWIRLVLWMLIGLDIYVCYGIKHSK
LEHMQKHRSGQTTLDMIGITLSVLCVITGLWHQQTVGWGESKVLLIISFVFAFTHLAFYLYRLGKQFTSLTR

Sequences:

>Translated_552_residues
MGLFIKKPLADLMTEANDSGSKSLKRILGPWSLIALGVGVIIGAGLFSITGAVAAGYTGPAITLSFAIAALGCCFAGLCY
AEFASMIPVAGSAYTYSYATMGELVAWIIGWDLVLEYCVAATTVSISWSRYLVVFLEGFGVHLPQALTACPWDGGIVNIP
AFVIVVLMSILLIRGTEGSSIFNGIIVFLKVSVVLVFVVLGWKYIRMENYTPYIPTNTGTLGEFGFSGILRGAAIVFFAF
LGFDAVSTAAQETKNPKRDMPIGILMSLVVCTILYMLFAHVMTGVVHYSAFAGQNGIAPVAIAIDHMGQMDASGVIRPDY
PWMNRAIVIAILLGYCSVIMVTLLGQSRVFLSMSRDGLLPPLFSHIHEKFRTPARSNFLFMLLVGTLAAFVPASVAGEMC
SIGTLFAFTLVCAGVLIVRKTMPDAPRSFKTPLVPFVPIAGIITCLVMMLFLPADTWIRLVLWMLIGLDIYVCYGIKHSK
LEHMQKHRSGQTTLDMIGITLSVLCVITGLWHQQTVGWGESKVLLIISFVFAFTHLAFYLYRLGKQFTSLTR
>Mature_551_residues
GLFIKKPLADLMTEANDSGSKSLKRILGPWSLIALGVGVIIGAGLFSITGAVAAGYTGPAITLSFAIAALGCCFAGLCYA
EFASMIPVAGSAYTYSYATMGELVAWIIGWDLVLEYCVAATTVSISWSRYLVVFLEGFGVHLPQALTACPWDGGIVNIPA
FVIVVLMSILLIRGTEGSSIFNGIIVFLKVSVVLVFVVLGWKYIRMENYTPYIPTNTGTLGEFGFSGILRGAAIVFFAFL
GFDAVSTAAQETKNPKRDMPIGILMSLVVCTILYMLFAHVMTGVVHYSAFAGQNGIAPVAIAIDHMGQMDASGVIRPDYP
WMNRAIVIAILLGYCSVIMVTLLGQSRVFLSMSRDGLLPPLFSHIHEKFRTPARSNFLFMLLVGTLAAFVPASVAGEMCS
IGTLFAFTLVCAGVLIVRKTMPDAPRSFKTPLVPFVPIAGIITCLVMMLFLPADTWIRLVLWMLIGLDIYVCYGIKHSKL
EHMQKHRSGQTTLDMIGITLSVLCVITGLWHQQTVGWGESKVLLIISFVFAFTHLAFYLYRLGKQFTSLTR

Specific function: Probable Amino-Acid Or Metabolite Transport Protein. [C]

COG id: COG0531

COG function: function code E; Amino acid transporters

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amino acid-polyamine-organocation (APC) superfamily [H]

Homologues:

Organism=Homo sapiens, GI4507047, Length=444, Percent_Identity=32.6576576576577, Blast_Score=191, Evalue=1e-48,
Organism=Homo sapiens, GI114326544, Length=428, Percent_Identity=32.0093457943925, Blast_Score=186, Evalue=5e-47,
Organism=Homo sapiens, GI114326550, Length=428, Percent_Identity=32.0093457943925, Blast_Score=186, Evalue=5e-47,
Organism=Homo sapiens, GI258614003, Length=428, Percent_Identity=32.9439252336449, Blast_Score=183, Evalue=4e-46,
Organism=Homo sapiens, GI258614005, Length=428, Percent_Identity=32.9439252336449, Blast_Score=183, Evalue=4e-46,
Organism=Homo sapiens, GI110347453, Length=420, Percent_Identity=31.6666666666667, Blast_Score=180, Evalue=3e-45,
Organism=Homo sapiens, GI258645169, Length=428, Percent_Identity=32.2429906542056, Blast_Score=180, Evalue=3e-45,
Organism=Homo sapiens, GI181337167, Length=417, Percent_Identity=32.1342925659472, Blast_Score=168, Evalue=1e-41,
Organism=Homo sapiens, GI186910308, Length=446, Percent_Identity=23.542600896861, Blast_Score=86, Evalue=1e-16,
Organism=Homo sapiens, GI186910306, Length=446, Percent_Identity=23.542600896861, Blast_Score=86, Evalue=1e-16,
Organism=Homo sapiens, GI186910304, Length=446, Percent_Identity=23.542600896861, Blast_Score=86, Evalue=1e-16,
Organism=Homo sapiens, GI115648063, Length=445, Percent_Identity=23.3707865168539, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI115648022, Length=445, Percent_Identity=23.3707865168539, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI71979932, Length=452, Percent_Identity=23.2300884955752, Blast_Score=79, Evalue=8e-15,
Organism=Homo sapiens, GI7657683, Length=393, Percent_Identity=24.4274809160305, Blast_Score=78, Evalue=2e-14,
Organism=Homo sapiens, GI187423910, Length=494, Percent_Identity=21.8623481781377, Blast_Score=73, Evalue=7e-13,
Organism=Homo sapiens, GI7657591, Length=494, Percent_Identity=21.8623481781377, Blast_Score=73, Evalue=7e-13,
Organism=Homo sapiens, GI33286428, Length=436, Percent_Identity=24.0825688073394, Blast_Score=68, Evalue=3e-11,
Organism=Escherichia coli, GI87081869, Length=477, Percent_Identity=24.5283018867925, Blast_Score=98, Evalue=2e-21,
Organism=Escherichia coli, GI87082250, Length=372, Percent_Identity=26.8817204301075, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI87082023, Length=470, Percent_Identity=22.7659574468085, Blast_Score=84, Evalue=3e-17,
Organism=Escherichia coli, GI87081708, Length=482, Percent_Identity=24.4813278008299, Blast_Score=76, Evalue=6e-15,
Organism=Escherichia coli, GI1788480, Length=468, Percent_Identity=20.7264957264957, Blast_Score=64, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17532491, Length=401, Percent_Identity=31.4214463840399, Blast_Score=199, Evalue=3e-51,
Organism=Caenorhabditis elegans, GI17531343, Length=511, Percent_Identity=29.5499021526419, Blast_Score=178, Evalue=5e-45,
Organism=Caenorhabditis elegans, GI17533459, Length=420, Percent_Identity=28.0952380952381, Blast_Score=157, Evalue=1e-38,
Organism=Caenorhabditis elegans, GI17540018, Length=487, Percent_Identity=26.0780287474333, Blast_Score=93, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI17568033, Length=490, Percent_Identity=25.1020408163265, Blast_Score=88, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI71993915, Length=427, Percent_Identity=22.248243559719, Blast_Score=82, Evalue=7e-16,
Organism=Caenorhabditis elegans, GI32566699, Length=439, Percent_Identity=23.4624145785877, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI71995388, Length=425, Percent_Identity=21.1764705882353, Blast_Score=73, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI71995382, Length=425, Percent_Identity=21.1764705882353, Blast_Score=73, Evalue=4e-13,
Organism=Drosophila melanogaster, GI221512776, Length=435, Percent_Identity=34.2528735632184, Blast_Score=239, Evalue=4e-63,
Organism=Drosophila melanogaster, GI24666159, Length=435, Percent_Identity=34.2528735632184, Blast_Score=239, Evalue=5e-63,
Organism=Drosophila melanogaster, GI24668806, Length=440, Percent_Identity=31.1363636363636, Blast_Score=208, Evalue=9e-54,
Organism=Drosophila melanogaster, GI21356285, Length=440, Percent_Identity=31.1363636363636, Blast_Score=208, Evalue=9e-54,
Organism=Drosophila melanogaster, GI24668802, Length=440, Percent_Identity=31.1363636363636, Blast_Score=208, Evalue=9e-54,
Organism=Drosophila melanogaster, GI24667468, Length=426, Percent_Identity=30.9859154929577, Blast_Score=204, Evalue=1e-52,
Organism=Drosophila melanogaster, GI281366235, Length=414, Percent_Identity=32.6086956521739, Blast_Score=176, Evalue=3e-44,
Organism=Drosophila melanogaster, GI116007820, Length=414, Percent_Identity=32.6086956521739, Blast_Score=176, Evalue=3e-44,
Organism=Drosophila melanogaster, GI116007818, Length=413, Percent_Identity=32.6876513317191, Blast_Score=174, Evalue=1e-43,
Organism=Drosophila melanogaster, GI85725152, Length=413, Percent_Identity=32.6876513317191, Blast_Score=174, Evalue=1e-43,
Organism=Drosophila melanogaster, GI161077963, Length=427, Percent_Identity=30.9133489461358, Blast_Score=151, Evalue=1e-36,
Organism=Drosophila melanogaster, GI21357367, Length=446, Percent_Identity=25.1121076233184, Blast_Score=89, Evalue=6e-18,
Organism=Drosophila melanogaster, GI221331183, Length=452, Percent_Identity=23.4513274336283, Blast_Score=83, Evalue=6e-16,
Organism=Drosophila melanogaster, GI17647653, Length=452, Percent_Identity=23.4513274336283, Blast_Score=83, Evalue=6e-16,
Organism=Drosophila melanogaster, GI24664379, Length=452, Percent_Identity=23.4513274336283, Blast_Score=83, Evalue=6e-16,
Organism=Drosophila melanogaster, GI24641993, Length=456, Percent_Identity=23.4649122807018, Blast_Score=69, Evalue=7e-12,
Organism=Drosophila melanogaster, GI24641995, Length=456, Percent_Identity=23.4649122807018, Blast_Score=69, Evalue=8e-12,
Organism=Drosophila melanogaster, GI24651635, Length=472, Percent_Identity=23.5169491525424, Blast_Score=67, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24651633, Length=472, Percent_Identity=23.5169491525424, Blast_Score=67, Evalue=3e-11,
Organism=Drosophila melanogaster, GI45550968, Length=436, Percent_Identity=22.4770642201835, Blast_Score=67, Evalue=4e-11,
Organism=Drosophila melanogaster, GI19921172, Length=436, Percent_Identity=22.4770642201835, Blast_Score=67, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004841
- InterPro:   IPR002293
- InterPro:   IPR015606 [H]

Pfam domain/function: PF00324 AA_permease [H]

EC number: NA

Molecular weight: Translated: 59916; Mature: 59785

Theoretical pI: Translated: 8.52; Mature: 8.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
6.3 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
6.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHCCC
>Mature Secondary Structure 
GLFIKKPLADLMTEANDSGSKSLKRILGPWSLIALGVGVIIGAGLFSITGAVAAGYTGP
CCCHHCHHHHHHHCCCCCHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCH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HHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9141694; 9384377 [H]