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The map label for this gene is gltA [H]

Identifier: 150007721

GI number: 150007721

Start: 1252806

End: 1254152

Strand: Direct

Name: gltA [H]

Synonym: BDI_1076

Alternate gene names: 150007721

Gene position: 1252806-1254152 (Clockwise)

Preceding gene: 150007720

Following gene: 150007723

Centisome position: 26.04

GC content: 44.69

Gene sequence:

>1347_bases
ATGTTGAAGAAAGAATATTTAATTTACAAATTGTCCGAGGCTGCCAGAGAGGCTTGCAAGATTGACAACGAACTTTTCCC
GATGTATAATGTGAAACGTGGCCTTCGTAACGAGGATGGTAGCGGCGTGTTAGTAGGATTGACCCAAGTCGGTAATGTAG
TAGGATACGAACGCTTGCCAGAGGGCGGTCTTAAAGCGATCCCCGGTAAGTTATTCTATAGAGGTTACGACGTAGAGGAT
TTAGCGCATGATTTCATCAAGGAAAAACGGTTCGGTTTTGAGGAAGTGGCTTATTTATTACTTTCTGGTAAACTCCCCGA
TAAAGAGGAATTATCAGCCTTTAAAGAACTGTTGAACGATAATATGCCCTTGGAGCAAAAGACCAAGATGAATATTCTGG
ATCTGGAAGGACAGAACATCATGAATATATTGGCTCGTAGCGTATTGGAGATGTATACCTTCGACGCAAACCCGGACGAC
ACCTCCCGAGATAACTTAATGCGCCAATCTATTGAATTGATCTCTAAGTTCCCGACGATTATCGCTTATGCCTACAATAT
TTATCGTCATAGCACACAGGGGCGTTCTTTACACATCCGTCATCCGCACGAGAACTTATCGATCGCAGAAAATTTCCTTC
ACATGCTGAAACGTGATTTCACGGATCTGGACGCACGTACGTTGGATTTGCTCTTGGTATTGCAAGCAGAACATGGTGGT
GGTAATAACTCTACGTTCACGGTACGCGTCACTAGTTCTACGGGAACGGATACGTACTCATCTATCGCAGCTGGTATCGG
CTCATTGAAAGGCCCGTTGCACGGAGGTGCCAATATTCAGGTAGTAGATATGTTCCATCATTTGAAAGAGAATATCGCGG
ATTGGAAGAACGTGGACGAGATCGATACTTATTTCATGCGGATGCTTAACAAAGAGGCTTATAACAAGACAGGCTTGATT
TATGGTATCGGCCATGCGGTCTATACGATTTCCGATCCCCGTGCGGTTGTATTAAAGGAACTAGCTCGTGATCTGGCAAA
AGAGAAAGGTCGCTCTGAGGAATTCGCCTTCCTTGAGTTATTAGAGGAAAGAGCGATCGAATGTTTCGCCAAGCATAAAG
GAACTAAGAAAAGGGTTTCCTCGAACGTGGACTTCTATTCCGGATTCGTTTATGAGATGATCGGTTTGCCACAGGAAATC
TATACGCCTTTATTCGCCATGGCCCGAATCGTGGGTTGGACCGCTCACCGTATCGAGGAGTTGAACTTTGACGGAAAACG
CATCATCCGTCCGGCTTACAAGAACGTTTTGGACGATAGGGAATATATCTCAATCAACGAGCGATAA

Upstream 100 bases:

>100_bases
ATGACTTGGCTCGTTTTATGCCGAACGGCAAATCTCTCGGCACCAAAGAATTTGGTGATCGTATCATCTCTATTATCGAA
ACAATTAAATTAGTATAGTC

Downstream 100 bases:

>100_bases
CACTAAAAAAATCATAGTTATGTTTTCTTTCATTCATAGTTATAAGTTGAAGGATTCATAACTATGATTTTTTAGCATGC
TCAGGCTTATAATAAGATCC

Product: citrate synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 448; Mature: 448

Protein sequence:

>448_residues
MLKKEYLIYKLSEAAREACKIDNELFPMYNVKRGLRNEDGSGVLVGLTQVGNVVGYERLPEGGLKAIPGKLFYRGYDVED
LAHDFIKEKRFGFEEVAYLLLSGKLPDKEELSAFKELLNDNMPLEQKTKMNILDLEGQNIMNILARSVLEMYTFDANPDD
TSRDNLMRQSIELISKFPTIIAYAYNIYRHSTQGRSLHIRHPHENLSIAENFLHMLKRDFTDLDARTLDLLLVLQAEHGG
GNNSTFTVRVTSSTGTDTYSSIAAGIGSLKGPLHGGANIQVVDMFHHLKENIADWKNVDEIDTYFMRMLNKEAYNKTGLI
YGIGHAVYTISDPRAVVLKELARDLAKEKGRSEEFAFLELLEERAIECFAKHKGTKKRVSSNVDFYSGFVYEMIGLPQEI
YTPLFAMARIVGWTAHRIEELNFDGKRIIRPAYKNVLDDREYISINER

Sequences:

>Translated_448_residues
MLKKEYLIYKLSEAAREACKIDNELFPMYNVKRGLRNEDGSGVLVGLTQVGNVVGYERLPEGGLKAIPGKLFYRGYDVED
LAHDFIKEKRFGFEEVAYLLLSGKLPDKEELSAFKELLNDNMPLEQKTKMNILDLEGQNIMNILARSVLEMYTFDANPDD
TSRDNLMRQSIELISKFPTIIAYAYNIYRHSTQGRSLHIRHPHENLSIAENFLHMLKRDFTDLDARTLDLLLVLQAEHGG
GNNSTFTVRVTSSTGTDTYSSIAAGIGSLKGPLHGGANIQVVDMFHHLKENIADWKNVDEIDTYFMRMLNKEAYNKTGLI
YGIGHAVYTISDPRAVVLKELARDLAKEKGRSEEFAFLELLEERAIECFAKHKGTKKRVSSNVDFYSGFVYEMIGLPQEI
YTPLFAMARIVGWTAHRIEELNFDGKRIIRPAYKNVLDDREYISINER
>Mature_448_residues
MLKKEYLIYKLSEAAREACKIDNELFPMYNVKRGLRNEDGSGVLVGLTQVGNVVGYERLPEGGLKAIPGKLFYRGYDVED
LAHDFIKEKRFGFEEVAYLLLSGKLPDKEELSAFKELLNDNMPLEQKTKMNILDLEGQNIMNILARSVLEMYTFDANPDD
TSRDNLMRQSIELISKFPTIIAYAYNIYRHSTQGRSLHIRHPHENLSIAENFLHMLKRDFTDLDARTLDLLLVLQAEHGG
GNNSTFTVRVTSSTGTDTYSSIAAGIGSLKGPLHGGANIQVVDMFHHLKENIADWKNVDEIDTYFMRMLNKEAYNKTGLI
YGIGHAVYTISDPRAVVLKELARDLAKEKGRSEEFAFLELLEERAIECFAKHKGTKKRVSSNVDFYSGFVYEMIGLPQEI
YTPLFAMARIVGWTAHRIEELNFDGKRIIRPAYKNVLDDREYISINER

Specific function: Catalyzes The Synthesis Of 2-Methylcitrate From Propionyl-CoA And Oxaloacetate. Also Catalyzes The Condensation Of Oxaloacetate With Acetyl-CoA But With A Lower Specificity. [C]

COG id: COG0372

COG function: function code C; Citrate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the citrate synthase family [H]

Homologues:

Organism=Homo sapiens, GI38327625, Length=389, Percent_Identity=26.2210796915167, Blast_Score=92, Evalue=8e-19,
Organism=Escherichia coli, GI1786527, Length=398, Percent_Identity=33.6683417085427, Blast_Score=180, Evalue=2e-46,
Organism=Escherichia coli, GI1786939, Length=372, Percent_Identity=32.5268817204301, Blast_Score=161, Evalue=8e-41,
Organism=Caenorhabditis elegans, GI17555174, Length=432, Percent_Identity=25.9259259259259, Blast_Score=91, Evalue=9e-19,
Organism=Saccharomyces cerevisiae, GI6319850, Length=412, Percent_Identity=27.4271844660194, Blast_Score=113, Evalue=6e-26,
Organism=Saccharomyces cerevisiae, GI6324328, Length=247, Percent_Identity=31.9838056680162, Blast_Score=100, Evalue=7e-22,
Organism=Saccharomyces cerevisiae, GI6325257, Length=409, Percent_Identity=26.161369193154, Blast_Score=80, Evalue=4e-16,
Organism=Drosophila melanogaster, GI24640124, Length=343, Percent_Identity=26.8221574344023, Blast_Score=102, Evalue=7e-22,
Organism=Drosophila melanogaster, GI24640126, Length=343, Percent_Identity=26.8221574344023, Blast_Score=102, Evalue=7e-22,
Organism=Drosophila melanogaster, GI21356863, Length=425, Percent_Identity=25.6470588235294, Blast_Score=86, Evalue=5e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011278
- InterPro:   IPR016142
- InterPro:   IPR016143
- InterPro:   IPR002020
- InterPro:   IPR016141
- InterPro:   IPR019810 [H]

Pfam domain/function: PF00285 Citrate_synt [H]

EC number: =2.3.3.1 [H]

Molecular weight: Translated: 51101; Mature: 51101

Theoretical pI: Translated: 6.34; Mature: 6.34

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKKEYLIYKLSEAAREACKIDNELFPMYNVKRGLRNEDGSGVLVGLTQVGNVVGYERLP
CCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCCCCEEEEEHHHHCCHHHHHHCC
EGGLKAIPGKLFYRGYDVEDLAHDFIKEKRFGFEEVAYLLLSGKLPDKEELSAFKELLND
CCCCHHCCCHHEECCCCHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCHHHHHHHHHHHCC
NMPLEQKTKMNILDLEGQNIMNILARSVLEMYTFDANPDDTSRDNLMRQSIELISKFPTI
CCCCCHHCCCCEEECCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHH
IAYAYNIYRHSTQGRSLHIRHPHENLSIAENFLHMLKRDFTDLDARTLDLLLVLQAEHGG
HHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHCCCHHHEEEEEEEEECCCC
GNNSTFTVRVTSSTGTDTYSSIAAGIGSLKGPLHGGANIQVVDMFHHLKENIADWKNVDE
CCCCEEEEEEECCCCCHHHHHHHHHHHHCCCCCCCCCCEEHHHHHHHHHHHHHHHCCCHH
IDTYFMRMLNKEAYNKTGLIYGIGHAVYTISDPRAVVLKELARDLAKEKGRSEEFAFLEL
HHHHHHHHHHHHHHCCCCEEEEECCEEEEECCCHHHHHHHHHHHHHHHCCCCHHHHHHHH
LEERAIECFAKHKGTKKRVSSNVDFYSGFVYEMIGLPQEIYTPLFAMARIVGWTAHRIEE
HHHHHHHHHHHCCCHHHHHHCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
LNFDGKRIIRPAYKNVLDDREYISINER
CCCCCHHHHHHHHHHHCCCCCEEECCCC
>Mature Secondary Structure
MLKKEYLIYKLSEAAREACKIDNELFPMYNVKRGLRNEDGSGVLVGLTQVGNVVGYERLP
CCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCCCCEEEEEHHHHCCHHHHHHCC
EGGLKAIPGKLFYRGYDVEDLAHDFIKEKRFGFEEVAYLLLSGKLPDKEELSAFKELLND
CCCCHHCCCHHEECCCCHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCHHHHHHHHHHHCC
NMPLEQKTKMNILDLEGQNIMNILARSVLEMYTFDANPDDTSRDNLMRQSIELISKFPTI
CCCCCHHCCCCEEECCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHH
IAYAYNIYRHSTQGRSLHIRHPHENLSIAENFLHMLKRDFTDLDARTLDLLLVLQAEHGG
HHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHCCCHHHEEEEEEEEECCCC
GNNSTFTVRVTSSTGTDTYSSIAAGIGSLKGPLHGGANIQVVDMFHHLKENIADWKNVDE
CCCCEEEEEEECCCCCHHHHHHHHHHHHCCCCCCCCCCEEHHHHHHHHHHHHHHHCCCHH
IDTYFMRMLNKEAYNKTGLIYGIGHAVYTISDPRAVVLKELARDLAKEKGRSEEFAFLEL
HHHHHHHHHHHHHHCCCCEEEEECCEEEEECCCHHHHHHHHHHHHHHHCCCCHHHHHHHH
LEERAIECFAKHKGTKKRVSSNVDFYSGFVYEMIGLPQEIYTPLFAMARIVGWTAHRIEE
HHHHHHHHHHHCCCHHHHHHCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
LNFDGKRIIRPAYKNVLDDREYISINER
CCCCCHHHHHHHHHHHCCCCCEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231 [H]