| Definition | Parabacteroides distasonis ATCC 8503 chromosome, complete genome. |
|---|---|
| Accession | NC_009615 |
| Length | 4,811,379 |
Click here to switch to the map view.
The map label for this gene is pbpC [H]
Identifier: 150007579
GI number: 150007579
Start: 1074077
End: 1076623
Strand: Reverse
Name: pbpC [H]
Synonym: BDI_0932
Alternate gene names: 150007579
Gene position: 1076623-1074077 (Counterclockwise)
Preceding gene: 150007580
Following gene: 150007577
Centisome position: 22.38
GC content: 56.89
Gene sequence:
>2547_bases ATGAGGAGAGTGTCAATTGGTATGATTGAGGCAGTACTCCTTATAAAGTACCGCAATACTCAGCCGGACAGTACCGCAGT ACTTCTTAAGGAGTACCGCAGTACTTTGCGCACAGTACTACAGTACTTCCTACGGAGTACTGGCAGATGCCTCAGCCATC TATCCAAGTCGCTACTACCGAGGCCGGGACGAGTGCCATGGCGCCTCCTCGCATCCCTCTTGGGGATCGGCGTGACGGCG TGGTGTATCCTGTATGGCATCGTGCCCCGGCAATTATTTCCCGCCCCCTGCTCTACCTTATTATATTCGGCCGAGGGCGA GCTTTTAGGCGCACGTATCGCACCGGACGGGCAATGGCGTTTCCCGGCGGCGGATAGCTTGCCTGATAAATTCGTGGATT GCTTGCTCACGTATGAGGATAAACGGTTCTTTTACCATCCCGGTATAGACCCCGCCGCCATCTTCCGGGCGATCCGCTTG AACGGGAAAGCGGGGCGTGTGGTGAGCGGAGGAAGTACCTTGACCATGCAATTGGCACGCATAGCGAGAGGGAACCAAGA CCGGACCTTCTACGAGAAAACGATCGAGATGTGCTGGGCGCTCTTCCTGGAAACCACCTATAGCAAACAAGAGATACTGA ACCTCTATGCCTCGCACGCTCCCTTCGGGGGAAACGTAATCGGGCTGGAGACCGCCGCATGGCGTTATTTCGGGCGAAGC GCCTCCGAGCTATCGTGGGCCGAGAGCGCCACGCTCGCGGTTCTTCCCAACTCCCCCGCCTTGATCCACCCCGGGAGAAA CCGGAAACAACTGAAGGAGAAGCGGGATCGCCTGTTGGCTTCCCTTCAGAAGAAAGGCGTATTGGAGGAAACCGAATACG AGCTGGCCTGCATGGAGCCACTTCCCGAAGCCCCTCTCCCTTTACCTAATGATGCCCCTCACCTGTTAGAAAGACTGGCC GCAGAACAACCGGGGCAACGCATCCAAACCTCCGTCCGCCAAGCCCTGCAACGGCAGACACAGGCCCTCGTAAACCGTTA TGCCCGTGAATACAGTTCCAACCATATCCATAATCTGGCGGCGATCGTAGCGGACGTGGAGACCGGGGAGGTATTGGCCT ACGCCGGAAACGCTACCTATCCGGCCGACGAGCGGCGGGGGAACCAAGTGGACATCATCACCTCGCCCCGCAGCACGGGA AGCATCCTCAAGCCCTTCCTGTATGCCGGTATGCTGCACGACGGGCTGTTGCTCCCCTCTATGCTGGTATCGGACGTGCC CTTGAATATAAATGGCTTCTCCCCCCATAATTACAACAAGACATTCTACGGGGCGGTACCGGCCCATGTAGCCATCGAAC GCTCCTTGAACGTCCCCTTGGTACGAATGCTCTCCCGGTATAATACCGGACGCTTTATGTCTTTACTGAAATCGTGGGGA ATGACTACCTTACGTTTCTCCGAGGAACATTACGGGGCCTCCTTGATCTTGGGAGGGGCCGAGGGAACCTTATGGGATCT TTCCGGTATGTATGCCTCCATGTCTCGTGTGCTTAAACATTACCGTACTTACAACGGACGCTATAATCCGGCGGACATCC ATCCGCTGACTCCCTTTCCGGCGGAGAGGAAGGAACCCATCCGTTCCCTTACCGATAGCCGGCTCACCGATAAGGCTCTC CTTTCCTCCGCGGCCCTGTGGTACACGTTCGAGGCGATGTCCGCCCTGAACCGTCCCGAGGAAGAGGCCGACTGGCAACA ATTCGAGTCGATGAAGCGGATCGCATGGAAGACCGGGACGAGTTACGGGGGACGAGACGCTTGGGCGATCGGCACGACTC CCCGCTACGTCGTCGGCGTATGGGCCGGTAACGCTTCCGGCGAGGGCCGTCCAGGACTTACGGGTGTCGGCAACGCCGCC CCGGTCCTTTTCGATCTCTTTTCCCTATTGCCCGGTAGCGAATGGTTCGACCTGCCCTACGATGAGACGCTTCCCCTGGC GATCTGCCGGAACAGCGGACATAAAGCCTCGCCCTACTGCGAGCAAACGGACACCTTATACATGCCGCTGTCCGGCAATA ACACGGGGGTCTGCCCCTACCATAAGCTCGTACATCTATCGGCGGACGGACGGTACAGGGTCAATAGTTCCTGCGAGTCT GTCGACCGGATGATCAGCCGCCCGTGGTTCGTGCTTCCTCCCGCGCAGGAGTATTACTACCGCAACTATCACATCGATTA TATCCCGCTCCCTCCGGTAAAACCCGGCTGCGGGCAAGACCAGAACCGCCAGATCGAACTGATCTATCCCGAGCATAACG CCATTCTCTACCTTCCGAAAGGCTTCTCCGGAAAGTCCGAGAAATTTATCTTCAAGGCCGCCCACGCCCGCCGTGACGCT ACGATTTACTGGCATCTGGACGAAAGCTATCTGGGAGAGACCACCGATAATCACCAGATCAGTTGCTCCGTGAGCCAAGG AAAACATCTCCTTACCCTCATCGACAACGAGGGGAACCAGAAGAAAATACAATTCGAGGTCAAGTAA
Upstream 100 bases:
>100_bases CGGCGAAGGGGCGAATTTCCACTCTCACCTAAAGAGCAAAGGATCGTGCTAAACGCCTTGCGAAGAGTCGGAGTGACGGA AGAGCTAAGGTTCGATCATT
Downstream 100 bases:
>100_bases AGCATCCGTTAAGCCTTGACCTTGACCCAAACAGCCAATTTGCCTCCCTTGACAAGGAAACGGCCTTTCCCTTCCTCATC AATCGCCACGGTATCTTTTA
Product: bifunctional family GT51 beta-glycosyltransferase/PBP transpeptidase
Products: NA
Alternate protein names: PBP-1c; PBP1c; Penicillin-insensitive transglycosylase; Peptidoglycan TGase; Transpeptidase-like module [H]
Number of amino acids: Translated: 848; Mature: 848
Protein sequence:
>848_residues MRRVSIGMIEAVLLIKYRNTQPDSTAVLLKEYRSTLRTVLQYFLRSTGRCLSHLSKSLLPRPGRVPWRLLASLLGIGVTA WCILYGIVPRQLFPAPCSTLLYSAEGELLGARIAPDGQWRFPAADSLPDKFVDCLLTYEDKRFFYHPGIDPAAIFRAIRL NGKAGRVVSGGSTLTMQLARIARGNQDRTFYEKTIEMCWALFLETTYSKQEILNLYASHAPFGGNVIGLETAAWRYFGRS ASELSWAESATLAVLPNSPALIHPGRNRKQLKEKRDRLLASLQKKGVLEETEYELACMEPLPEAPLPLPNDAPHLLERLA AEQPGQRIQTSVRQALQRQTQALVNRYAREYSSNHIHNLAAIVADVETGEVLAYAGNATYPADERRGNQVDIITSPRSTG SILKPFLYAGMLHDGLLLPSMLVSDVPLNINGFSPHNYNKTFYGAVPAHVAIERSLNVPLVRMLSRYNTGRFMSLLKSWG MTTLRFSEEHYGASLILGGAEGTLWDLSGMYASMSRVLKHYRTYNGRYNPADIHPLTPFPAERKEPIRSLTDSRLTDKAL LSSAALWYTFEAMSALNRPEEEADWQQFESMKRIAWKTGTSYGGRDAWAIGTTPRYVVGVWAGNASGEGRPGLTGVGNAA PVLFDLFSLLPGSEWFDLPYDETLPLAICRNSGHKASPYCEQTDTLYMPLSGNNTGVCPYHKLVHLSADGRYRVNSSCES VDRMISRPWFVLPPAQEYYYRNYHIDYIPLPPVKPGCGQDQNRQIELIYPEHNAILYLPKGFSGKSEKFIFKAAHARRDA TIYWHLDESYLGETTDNHQISCSVSQGKHLLTLIDNEGNQKKIQFEVK
Sequences:
>Translated_848_residues MRRVSIGMIEAVLLIKYRNTQPDSTAVLLKEYRSTLRTVLQYFLRSTGRCLSHLSKSLLPRPGRVPWRLLASLLGIGVTA WCILYGIVPRQLFPAPCSTLLYSAEGELLGARIAPDGQWRFPAADSLPDKFVDCLLTYEDKRFFYHPGIDPAAIFRAIRL NGKAGRVVSGGSTLTMQLARIARGNQDRTFYEKTIEMCWALFLETTYSKQEILNLYASHAPFGGNVIGLETAAWRYFGRS ASELSWAESATLAVLPNSPALIHPGRNRKQLKEKRDRLLASLQKKGVLEETEYELACMEPLPEAPLPLPNDAPHLLERLA AEQPGQRIQTSVRQALQRQTQALVNRYAREYSSNHIHNLAAIVADVETGEVLAYAGNATYPADERRGNQVDIITSPRSTG SILKPFLYAGMLHDGLLLPSMLVSDVPLNINGFSPHNYNKTFYGAVPAHVAIERSLNVPLVRMLSRYNTGRFMSLLKSWG MTTLRFSEEHYGASLILGGAEGTLWDLSGMYASMSRVLKHYRTYNGRYNPADIHPLTPFPAERKEPIRSLTDSRLTDKAL LSSAALWYTFEAMSALNRPEEEADWQQFESMKRIAWKTGTSYGGRDAWAIGTTPRYVVGVWAGNASGEGRPGLTGVGNAA PVLFDLFSLLPGSEWFDLPYDETLPLAICRNSGHKASPYCEQTDTLYMPLSGNNTGVCPYHKLVHLSADGRYRVNSSCES VDRMISRPWFVLPPAQEYYYRNYHIDYIPLPPVKPGCGQDQNRQIELIYPEHNAILYLPKGFSGKSEKFIFKAAHARRDA TIYWHLDESYLGETTDNHQISCSVSQGKHLLTLIDNEGNQKKIQFEVK >Mature_848_residues MRRVSIGMIEAVLLIKYRNTQPDSTAVLLKEYRSTLRTVLQYFLRSTGRCLSHLSKSLLPRPGRVPWRLLASLLGIGVTA WCILYGIVPRQLFPAPCSTLLYSAEGELLGARIAPDGQWRFPAADSLPDKFVDCLLTYEDKRFFYHPGIDPAAIFRAIRL NGKAGRVVSGGSTLTMQLARIARGNQDRTFYEKTIEMCWALFLETTYSKQEILNLYASHAPFGGNVIGLETAAWRYFGRS ASELSWAESATLAVLPNSPALIHPGRNRKQLKEKRDRLLASLQKKGVLEETEYELACMEPLPEAPLPLPNDAPHLLERLA AEQPGQRIQTSVRQALQRQTQALVNRYAREYSSNHIHNLAAIVADVETGEVLAYAGNATYPADERRGNQVDIITSPRSTG SILKPFLYAGMLHDGLLLPSMLVSDVPLNINGFSPHNYNKTFYGAVPAHVAIERSLNVPLVRMLSRYNTGRFMSLLKSWG MTTLRFSEEHYGASLILGGAEGTLWDLSGMYASMSRVLKHYRTYNGRYNPADIHPLTPFPAERKEPIRSLTDSRLTDKAL LSSAALWYTFEAMSALNRPEEEADWQQFESMKRIAWKTGTSYGGRDAWAIGTTPRYVVGVWAGNASGEGRPGLTGVGNAA PVLFDLFSLLPGSEWFDLPYDETLPLAICRNSGHKASPYCEQTDTLYMPLSGNNTGVCPYHKLVHLSADGRYRVNSSCES VDRMISRPWFVLPPAQEYYYRNYHIDYIPLPPVKPGCGQDQNRQIELIYPEHNAILYLPKGFSGKSEKFIFKAAHARRDA TIYWHLDESYLGETTDNHQISCSVSQGKHLLTLIDNEGNQKKIQFEVK
Specific function: Cell wall formation. The enzyme has a penicillin- insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a transpeptidase C-terminal domain which may not be functional [H]
COG id: COG4953
COG function: function code M; Membrane carboxypeptidase/penicillin-binding protein PbpC
Gene ontology:
Cell location: Cell inner membrane; Single-pass type II membrane protein [H]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: In the C-terminal section; belongs to the transpeptidase family [H]
Homologues:
Organism=Escherichia coli, GI1788867, Length=757, Percent_Identity=29.9867899603699, Blast_Score=303, Evalue=3e-83, Organism=Escherichia coli, GI87082258, Length=270, Percent_Identity=30.3703703703704, Blast_Score=115, Evalue=1e-26, Organism=Escherichia coli, GI1786343, Length=547, Percent_Identity=25.9597806215722, Blast_Score=111, Evalue=2e-25, Organism=Escherichia coli, GI1789601, Length=125, Percent_Identity=38.4, Blast_Score=78, Evalue=2e-15,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR012338 - InterPro: IPR001264 - InterPro: IPR011815 - InterPro: IPR009647 - InterPro: IPR001460 [H]
Pfam domain/function: PF06832 BiPBP_C; PF00912 Transgly; PF00905 Transpeptidase [H]
EC number: 2.4.2.-
Molecular weight: Translated: 95100; Mature: 95100
Theoretical pI: Translated: 8.73; Mature: 8.73
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.4 %Cys (Translated Protein) 1.9 %Met (Translated Protein) 3.3 %Cys+Met (Translated Protein) 1.4 %Cys (Mature Protein) 1.9 %Met (Mature Protein) 3.3 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MRRVSIGMIEAVLLIKYRNTQPDSTAVLLKEYRSTLRTVLQYFLRSTGRCLSHLSKSLLP CCCCHHHHHEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC RPGRVPWRLLASLLGIGVTAWCILYGIVPRQLFPAPCSTLLYSAEGELLGARIAPDGQWR CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHEECCCCCEEEEEECCCCCCC FPAADSLPDKFVDCLLTYEDKRFFYHPGIDPAAIFRAIRLNGKAGRVVSGGSTLTMQLAR CCCCCCCHHHHHHHHHEECCCEEEECCCCCHHHHHHHHHCCCCCCCEEECCCHHHHHHHH IARGNQDRTFYEKTIEMCWALFLETTYSKQEILNLYASHAPFGGNVIGLETAAWRYFGRS HHCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCEEECCHHHHHHHCCC ASELSWAESATLAVLPNSPALIHPGRNRKQLKEKRDRLLASLQKKGVLEETEYELACMEP CCCCCCCCCCEEEEECCCCEEECCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCEEECCC LPEAPLPLPNDAPHLLERLAAEQPGQRIQTSVRQALQRQTQALVNRYAREYSSNHIHNLA CCCCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH AIVADVETGEVLAYAGNATYPADERRGNQVDIITSPRSTGSILKPFLYAGMLHDGLLLPS HHHEECCCCCEEEEECCCCCCCHHCCCCEEEEEECCCCCCHHHHHHHHHHHHHCCHHHHH MLVSDVPLNINGFSPHNYNKTFYGAVPAHVAIERSLNVPLVRMLSRYNTGRFMSLLKSWG HHHHCCCCCCCCCCCCCCCCEEECCCCCCEEECCCCCCHHHHHHHHCCCHHHHHHHHHCC MTTLRFSEEHYGASLILGGAEGTLWDLSGMYASMSRVLKHYRTYNGRYNPADIHPLTPFP CEEEEECCCCCCCEEEEECCCCCEEEHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCC AERKEPIRSLTDSRLTDKALLSSAALWYTFEAMSALNRPEEEADWQQFESMKRIAWKTGT CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCC SYGGRDAWAIGTTPRYVVGVWAGNASGEGRPGLTGVGNAAPVLFDLFSLLPGSEWFDLPY CCCCCCEEEECCCCCEEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCC DETLPLAICRNSGHKASPYCEQTDTLYMPLSGNNTGVCPYHKLVHLSADGRYRVNSSCES CCCCCEEEECCCCCCCCCCCCCCCEEEEEECCCCCCCCCCEEEEEECCCCCEEECCHHHH VDRMISRPWFVLPPAQEYYYRNYHIDYIPLPPVKPGCGQDQNRQIELIYPEHNAILYLPK HHHHHHCCEEEECCHHHHHEECEEEEEEECCCCCCCCCCCCCCEEEEEECCCCEEEEECC GFSGKSEKFIFKAAHARRDATIYWHLDESYLGETTDNHQISCSVSQGKHLLTLIDNEGNQ CCCCCCCEEEEEEHHCCCCCEEEEEECHHHCCCCCCCCEEEEEECCCCEEEEEEECCCCC KKIQFEVK EEEEEEEC >Mature Secondary Structure MRRVSIGMIEAVLLIKYRNTQPDSTAVLLKEYRSTLRTVLQYFLRSTGRCLSHLSKSLLP CCCCHHHHHEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC RPGRVPWRLLASLLGIGVTAWCILYGIVPRQLFPAPCSTLLYSAEGELLGARIAPDGQWR CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHEECCCCCEEEEEECCCCCCC FPAADSLPDKFVDCLLTYEDKRFFYHPGIDPAAIFRAIRLNGKAGRVVSGGSTLTMQLAR CCCCCCCHHHHHHHHHEECCCEEEECCCCCHHHHHHHHHCCCCCCCEEECCCHHHHHHHH IARGNQDRTFYEKTIEMCWALFLETTYSKQEILNLYASHAPFGGNVIGLETAAWRYFGRS HHCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCEEECCHHHHHHHCCC ASELSWAESATLAVLPNSPALIHPGRNRKQLKEKRDRLLASLQKKGVLEETEYELACMEP CCCCCCCCCCEEEEECCCCEEECCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCEEECCC LPEAPLPLPNDAPHLLERLAAEQPGQRIQTSVRQALQRQTQALVNRYAREYSSNHIHNLA CCCCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH AIVADVETGEVLAYAGNATYPADERRGNQVDIITSPRSTGSILKPFLYAGMLHDGLLLPS HHHEECCCCCEEEEECCCCCCCHHCCCCEEEEEECCCCCCHHHHHHHHHHHHHCCHHHHH MLVSDVPLNINGFSPHNYNKTFYGAVPAHVAIERSLNVPLVRMLSRYNTGRFMSLLKSWG HHHHCCCCCCCCCCCCCCCCEEECCCCCCEEECCCCCCHHHHHHHHCCCHHHHHHHHHCC MTTLRFSEEHYGASLILGGAEGTLWDLSGMYASMSRVLKHYRTYNGRYNPADIHPLTPFP CEEEEECCCCCCCEEEEECCCCCEEEHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCC AERKEPIRSLTDSRLTDKALLSSAALWYTFEAMSALNRPEEEADWQQFESMKRIAWKTGT CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCC SYGGRDAWAIGTTPRYVVGVWAGNASGEGRPGLTGVGNAAPVLFDLFSLLPGSEWFDLPY CCCCCCEEEECCCCCEEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCC DETLPLAICRNSGHKASPYCEQTDTLYMPLSGNNTGVCPYHKLVHLSADGRYRVNSSCES CCCCCEEEECCCCCCCCCCCCCCCEEEEEECCCCCCCCCCEEEEEECCCCCEEECCHHHH VDRMISRPWFVLPPAQEYYYRNYHIDYIPLPPVKPGCGQDQNRQIELIYPEHNAILYLPK HHHHHHCCEEEECCHHHHHEECEEEEEEECCCCCCCCCCCCCCEEEEEECCCCEEEEECC GFSGKSEKFIFKAAHARRDATIYWHLDESYLGETTDNHQISCSVSQGKHLLTLIDNEGNQ CCCCCCCEEEEEEHHCCCCCEEEEEECHHHCCCCCCCCEEEEEECCCCEEEEEEECCCCC KKIQFEVK EEEEEEEC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 6.0
TargetDB status: NA
Availability: NA
References: 10542235; 9205837; 9278503; 9841666 [H]