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The map label for this gene is malL [H]

Identifier: 150007577

GI number: 150007577

Start: 1070748

End: 1072514

Strand: Reverse

Name: malL [H]

Synonym: BDI_0930

Alternate gene names: 150007577

Gene position: 1072514-1070748 (Counterclockwise)

Preceding gene: 150007579

Following gene: 150007576

Centisome position: 22.29

GC content: 46.86

Gene sequence:

>1767_bases
ATGGATTCAAAGCATGTTACAGAGAGTACGTCCGGTCAAGAGGACATTCAAAAGACTTGGTGGAAAGAAGCGATTATATA
TCAAATCTATCCCCGTAGCTTTCAAGACAGCGATGGCGACGGAATCGGTGACTTAAACGGTATTACCTCCCGCCTGGATT
ATATACAAAGCTTGGGTGTGGATATCATCTGGTTAAACCCGATCTTTCTCTCTCCCAACGATGATAATGGCTACGACATC
AGCGACTATCGGGAAATCATGCGGGAATTCGGTACGATGGAAGATTTCGACCGCCTCCTGAAAGAGATTCATAAACGGGA
GATGCGACTGGTACTGGACTTGGTAGTAAACCATACCAGCGACGAGCATCCTTGGTTCGAGGAAGCCCGTAAATCCAGAC
ATAATCCCTATTATAATTATTACCATTGGTGGCCGGCCGAGAAAGGTGAGCCTCCCTTGCGCCTCAGCTATTTCGACGAG
GAAGGCAACGCTTGGATGTATAACAAGCCAACCGACTCGTATTACCTGCATTATTTCTCCCGGAAACAACCCGACTTAAA
TTGGGAGAACCCGGAGGTACGCCAAGAGATTTTCGATATGATGCGCTTCTGGTTCGATAAAGGGATAGACGGTTTTCGCA
TGGATTCTATCTCTCTTATCGCCAAAGATCCCTCATTCCCTCTCATAGATTCCAAGAAATATCCGGATATCTTTTCTTTC
TATGCCAAAGAGCCTCGCCTACACCTCTATCTTCACGAGATGAATCGGCAGGTATTAAGCAAATACGATTGTATGAGTGT
TGGAGAAGGTTCGGCCGTGATGGTAGATGATGTCGCTAAATTTGTCGATCCGGCCCGGGAAGAGTTGAATATGCTTTATC
ATTTCGACGCCGCCCGCATCCGGAATACAACCCTACCGGACAATCCGGAATCCGGTATAGACTATAGCTTGATCGCCCTA
AAGAAGATGTTTACGGAATGGGATAAGGCGGTAGATAAGGGTTGGCCCTCGATCTACTTGGGTAATCATGACCAGCCCCG
TATGGTCAGTCGCTTTGGTAGCGATAAGGATGAGTTCAGGGCCTTGTCCGCCAAGATGCTTATTACTTTTCTGCTTACGA
TGAAAGGAACGCCTTATTGGTTCGCCGGGGACGAGATAGGTATGCGTAACATTCGGTTCGACCGTATCGAGAATTATAAC
GATATCGATACGATCAACCGCTATAAGAAAGCGAAAGCAGAGGGTAAAGATCCGCAGGCGGTATTGGACGAACAGAAAGA
GACCGGACGAGACAACGCCCGCACTCCTTTCCAATGGGATCGCTCGCCGGAAGCGGGATTTACGGCAGGAACCCCTTGGT
TAAAGGTAAATCCAGATTATACTTGGATAAACGTAACGGACGAAGAAAAAGATCCGACCTCCATACTTAATTATTTTAAG
AAAGTAGTCAGCTTCCGTAAGGAGAATCCGAGTTTGATTTATGGCAGTTATCATTTGCTGGATGCGGAGAATCCCCAATC
CTATACCTTCTTACGCAAGACTGGGGCCGACACTTATCTGATTATGCTCAATTTCTCCCCCAAGGCGGCAATCTCCACTC
CGGGGATAGATATGAGTAACGCACACGTCCTATTGGACAATTACGGGGCCCGAAGTCATATGGCGCCTCAAAAAGATATC
ACGCTCCGTCCTTTCGAAGCGATTGTCTTTCAATTGAACCATCCCGTCTATGAATCCTTCATAGATTCGCTAGATCTTTT
GGAATGA

Upstream 100 bases:

>100_bases
TCTTCTATTTGTTGATAAAACAACACTTCTCAAGCGTCATAAGTTGCTGAAACTAACCACCACCTCCTTTTGTTATAGTA
AAAAACTAAAGAATAATAAG

Downstream 100 bases:

>100_bases
TTCGTTAAAAAGAGGTACAAAGCGCAACTAAAGACTTTTAGGATGTGTTTAAATACAAAGCATCAGAACTTTTTAATAAA
ATATAAAACTATTCGTTATG

Product: glycoside hydrolase family alpha-glucosidase

Products: NA

Alternate protein names: Dextrin 6-alpha-D-glucanohydrolase; Oligosaccharide alpha-1,6-glucosidase; Sucrase-isomaltase; Isomaltase [H]

Number of amino acids: Translated: 588; Mature: 588

Protein sequence:

>588_residues
MDSKHVTESTSGQEDIQKTWWKEAIIYQIYPRSFQDSDGDGIGDLNGITSRLDYIQSLGVDIIWLNPIFLSPNDDNGYDI
SDYREIMREFGTMEDFDRLLKEIHKREMRLVLDLVVNHTSDEHPWFEEARKSRHNPYYNYYHWWPAEKGEPPLRLSYFDE
EGNAWMYNKPTDSYYLHYFSRKQPDLNWENPEVRQEIFDMMRFWFDKGIDGFRMDSISLIAKDPSFPLIDSKKYPDIFSF
YAKEPRLHLYLHEMNRQVLSKYDCMSVGEGSAVMVDDVAKFVDPAREELNMLYHFDAARIRNTTLPDNPESGIDYSLIAL
KKMFTEWDKAVDKGWPSIYLGNHDQPRMVSRFGSDKDEFRALSAKMLITFLLTMKGTPYWFAGDEIGMRNIRFDRIENYN
DIDTINRYKKAKAEGKDPQAVLDEQKETGRDNARTPFQWDRSPEAGFTAGTPWLKVNPDYTWINVTDEEKDPTSILNYFK
KVVSFRKENPSLIYGSYHLLDAENPQSYTFLRKTGADTYLIMLNFSPKAAISTPGIDMSNAHVLLDNYGARSHMAPQKDI
TLRPFEAIVFQLNHPVYESFIDSLDLLE

Sequences:

>Translated_588_residues
MDSKHVTESTSGQEDIQKTWWKEAIIYQIYPRSFQDSDGDGIGDLNGITSRLDYIQSLGVDIIWLNPIFLSPNDDNGYDI
SDYREIMREFGTMEDFDRLLKEIHKREMRLVLDLVVNHTSDEHPWFEEARKSRHNPYYNYYHWWPAEKGEPPLRLSYFDE
EGNAWMYNKPTDSYYLHYFSRKQPDLNWENPEVRQEIFDMMRFWFDKGIDGFRMDSISLIAKDPSFPLIDSKKYPDIFSF
YAKEPRLHLYLHEMNRQVLSKYDCMSVGEGSAVMVDDVAKFVDPAREELNMLYHFDAARIRNTTLPDNPESGIDYSLIAL
KKMFTEWDKAVDKGWPSIYLGNHDQPRMVSRFGSDKDEFRALSAKMLITFLLTMKGTPYWFAGDEIGMRNIRFDRIENYN
DIDTINRYKKAKAEGKDPQAVLDEQKETGRDNARTPFQWDRSPEAGFTAGTPWLKVNPDYTWINVTDEEKDPTSILNYFK
KVVSFRKENPSLIYGSYHLLDAENPQSYTFLRKTGADTYLIMLNFSPKAAISTPGIDMSNAHVLLDNYGARSHMAPQKDI
TLRPFEAIVFQLNHPVYESFIDSLDLLE
>Mature_588_residues
MDSKHVTESTSGQEDIQKTWWKEAIIYQIYPRSFQDSDGDGIGDLNGITSRLDYIQSLGVDIIWLNPIFLSPNDDNGYDI
SDYREIMREFGTMEDFDRLLKEIHKREMRLVLDLVVNHTSDEHPWFEEARKSRHNPYYNYYHWWPAEKGEPPLRLSYFDE
EGNAWMYNKPTDSYYLHYFSRKQPDLNWENPEVRQEIFDMMRFWFDKGIDGFRMDSISLIAKDPSFPLIDSKKYPDIFSF
YAKEPRLHLYLHEMNRQVLSKYDCMSVGEGSAVMVDDVAKFVDPAREELNMLYHFDAARIRNTTLPDNPESGIDYSLIAL
KKMFTEWDKAVDKGWPSIYLGNHDQPRMVSRFGSDKDEFRALSAKMLITFLLTMKGTPYWFAGDEIGMRNIRFDRIENYN
DIDTINRYKKAKAEGKDPQAVLDEQKETGRDNARTPFQWDRSPEAGFTAGTPWLKVNPDYTWINVTDEEKDPTSILNYFK
KVVSFRKENPSLIYGSYHLLDAENPQSYTFLRKTGADTYLIMLNFSPKAAISTPGIDMSNAHVLLDNYGARSHMAPQKDI
TLRPFEAIVFQLNHPVYESFIDSLDLLE

Specific function: Unknown

COG id: COG0366

COG function: function code G; Glycosidases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 13 family [H]

Homologues:

Organism=Homo sapiens, GI187423904, Length=575, Percent_Identity=28.3478260869565, Blast_Score=233, Evalue=3e-61,
Organism=Homo sapiens, GI61744477, Length=127, Percent_Identity=33.0708661417323, Blast_Score=73, Evalue=9e-13,
Organism=Homo sapiens, GI61744475, Length=127, Percent_Identity=33.0708661417323, Blast_Score=73, Evalue=1e-12,
Organism=Homo sapiens, GI65506891, Length=127, Percent_Identity=33.0708661417323, Blast_Score=72, Evalue=1e-12,
Organism=Homo sapiens, GI61744479, Length=127, Percent_Identity=33.0708661417323, Blast_Score=72, Evalue=1e-12,
Organism=Homo sapiens, GI61744481, Length=127, Percent_Identity=33.0708661417323, Blast_Score=72, Evalue=1e-12,
Organism=Homo sapiens, GI61744483, Length=127, Percent_Identity=33.0708661417323, Blast_Score=72, Evalue=2e-12,
Organism=Escherichia coli, GI1790687, Length=558, Percent_Identity=39.426523297491, Blast_Score=419, Evalue=1e-118,
Organism=Escherichia coli, GI1786604, Length=544, Percent_Identity=22.6102941176471, Blast_Score=90, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI25147709, Length=587, Percent_Identity=25.0425894378194, Blast_Score=147, Evalue=2e-35,
Organism=Caenorhabditis elegans, GI32565753, Length=233, Percent_Identity=31.7596566523605, Blast_Score=130, Evalue=2e-30,
Organism=Saccharomyces cerevisiae, GI6324416, Length=589, Percent_Identity=36.6723259762309, Blast_Score=346, Evalue=5e-96,
Organism=Saccharomyces cerevisiae, GI6322245, Length=584, Percent_Identity=36.6438356164384, Blast_Score=346, Evalue=7e-96,
Organism=Saccharomyces cerevisiae, GI6322241, Length=589, Percent_Identity=36.6723259762309, Blast_Score=345, Evalue=8e-96,
Organism=Saccharomyces cerevisiae, GI6322021, Length=589, Percent_Identity=36.6723259762309, Blast_Score=345, Evalue=8e-96,
Organism=Saccharomyces cerevisiae, GI6321726, Length=596, Percent_Identity=35.0671140939597, Blast_Score=345, Evalue=1e-95,
Organism=Saccharomyces cerevisiae, GI6321731, Length=577, Percent_Identity=34.8353552859619, Blast_Score=320, Evalue=4e-88,
Organism=Saccharomyces cerevisiae, GI6319776, Length=577, Percent_Identity=34.8353552859619, Blast_Score=319, Evalue=7e-88,
Organism=Drosophila melanogaster, GI221330053, Length=612, Percent_Identity=31.6993464052288, Blast_Score=271, Evalue=1e-72,
Organism=Drosophila melanogaster, GI24586599, Length=611, Percent_Identity=32.4058919803601, Blast_Score=260, Evalue=2e-69,
Organism=Drosophila melanogaster, GI24583745, Length=589, Percent_Identity=32.597623089983, Blast_Score=258, Evalue=6e-69,
Organism=Drosophila melanogaster, GI24586593, Length=509, Percent_Identity=34.1846758349705, Blast_Score=256, Evalue=3e-68,
Organism=Drosophila melanogaster, GI24586591, Length=540, Percent_Identity=34.0740740740741, Blast_Score=253, Evalue=3e-67,
Organism=Drosophila melanogaster, GI24586587, Length=601, Percent_Identity=30.7820299500832, Blast_Score=252, Evalue=5e-67,
Organism=Drosophila melanogaster, GI45549022, Length=544, Percent_Identity=33.8235294117647, Blast_Score=251, Evalue=1e-66,
Organism=Drosophila melanogaster, GI24583747, Length=490, Percent_Identity=34.2857142857143, Blast_Score=249, Evalue=3e-66,
Organism=Drosophila melanogaster, GI24583749, Length=490, Percent_Identity=34.2857142857143, Blast_Score=249, Evalue=4e-66,
Organism=Drosophila melanogaster, GI24586589, Length=534, Percent_Identity=33.1460674157303, Blast_Score=246, Evalue=3e-65,
Organism=Drosophila melanogaster, GI24586597, Length=550, Percent_Identity=31.6363636363636, Blast_Score=237, Evalue=2e-62,
Organism=Drosophila melanogaster, GI281360393, Length=485, Percent_Identity=30.7216494845361, Blast_Score=181, Evalue=1e-45,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013780
- InterPro:   IPR006047
- InterPro:   IPR006589
- InterPro:   IPR017853
- InterPro:   IPR013781 [H]

Pfam domain/function: PF00128 Alpha-amylase [H]

EC number: =3.2.1.10 [H]

Molecular weight: Translated: 68861; Mature: 68861

Theoretical pI: Translated: 4.86; Mature: 4.86

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDSKHVTESTSGQEDIQKTWWKEAIIYQIYPRSFQDSDGDGIGDLNGITSRLDYIQSLGV
CCCCCCCCCCCCHHHHHHHHHHHEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHCCC
DIIWLNPIFLSPNDDNGYDISDYREIMREFGTMEDFDRLLKEIHKREMRLVLDLVVNHTS
EEEEECEEEECCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCC
DEHPWFEEARKSRHNPYYNYYHWWPAEKGEPPLRLSYFDEEGNAWMYNKPTDSYYLHYFS
CCCCHHHHHHHHCCCCCCCEEEEECCCCCCCCEEEEEEECCCCEEEECCCCCCEEEEEEC
RKQPDLNWENPEVRQEIFDMMRFWFDKGIDGFRMDSISLIAKDPSFPLIDSKKYPDIFSF
CCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEECCEEEEECCCCCCCCCCCCCCHHHHH
YAKEPRLHLYLHEMNRQVLSKYDCMSVGEGSAVMVDDVAKFVDPAREELNMLYHFDAARI
HCCCCCEEEHHHHHHHHHHHHHCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHEECHHHH
RNTTLPDNPESGIDYSLIALKKMFTEWDKAVDKGWPSIYLGNHDQPRMVSRFGSDKDEFR
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHCCCCHHHHH
ALSAKMLITFLLTMKGTPYWFAGDEIGMRNIRFDRIENYNDIDTINRYKKAKAEGKDPQA
HHHHHHHHHHHHHHCCCCEEECCCCCCCCCCCHHHCCCCCCHHHHHHHHHHHCCCCCHHH
VLDEQKETGRDNARTPFQWDRSPEAGFTAGTPWLKVNPDYTWINVTDEEKDPTSILNYFK
HHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCEEEEEECCCCCCHHHHHHHHH
KVVSFRKENPSLIYGSYHLLDAENPQSYTFLRKTGADTYLIMLNFSPKAAISTPGIDMSN
HHHHHHCCCCCEEEEEEEEEECCCCCCEEEEEECCCCEEEEEEECCCCCCCCCCCCCCCC
AHVLLDNYGARSHMAPQKDITLRPFEAIVFQLNHPVYESFIDSLDLLE
CEEEEECCCCCCCCCCCCCCEECCHHHHHHHCCCHHHHHHHHHHHCCC
>Mature Secondary Structure
MDSKHVTESTSGQEDIQKTWWKEAIIYQIYPRSFQDSDGDGIGDLNGITSRLDYIQSLGV
CCCCCCCCCCCCHHHHHHHHHHHEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHCCC
DIIWLNPIFLSPNDDNGYDISDYREIMREFGTMEDFDRLLKEIHKREMRLVLDLVVNHTS
EEEEECEEEECCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCC
DEHPWFEEARKSRHNPYYNYYHWWPAEKGEPPLRLSYFDEEGNAWMYNKPTDSYYLHYFS
CCCCHHHHHHHHCCCCCCCEEEEECCCCCCCCEEEEEEECCCCEEEECCCCCCEEEEEEC
RKQPDLNWENPEVRQEIFDMMRFWFDKGIDGFRMDSISLIAKDPSFPLIDSKKYPDIFSF
CCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEECCEEEEECCCCCCCCCCCCCCHHHHH
YAKEPRLHLYLHEMNRQVLSKYDCMSVGEGSAVMVDDVAKFVDPAREELNMLYHFDAARI
HCCCCCEEEHHHHHHHHHHHHHCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHEECHHHH
RNTTLPDNPESGIDYSLIALKKMFTEWDKAVDKGWPSIYLGNHDQPRMVSRFGSDKDEFR
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHCCCCHHHHH
ALSAKMLITFLLTMKGTPYWFAGDEIGMRNIRFDRIENYNDIDTINRYKKAKAEGKDPQA
HHHHHHHHHHHHHHCCCCEEECCCCCCCCCCCHHHCCCCCCHHHHHHHHHHHCCCCCHHH
VLDEQKETGRDNARTPFQWDRSPEAGFTAGTPWLKVNPDYTWINVTDEEKDPTSILNYFK
HHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCEEEEEECCCCCCHHHHHHHHH
KVVSFRKENPSLIYGSYHLLDAENPQSYTFLRKTGADTYLIMLNFSPKAAISTPGIDMSN
HHHHHHCCCCCEEEEEEEEEECCCCCCEEEEEECCCCEEEEEEECCCCCCCCCCCCCCCC
AHVLLDNYGARSHMAPQKDITLRPFEAIVFQLNHPVYESFIDSLDLLE
CEEEEECCCCCCCCCCCCCCEECCHHHHHHHCCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1761534 [H]