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The map label for this gene is phoR [H]

Identifier: 150007456

GI number: 150007456

Start: 952790

End: 954559

Strand: Reverse

Name: phoR [H]

Synonym: BDI_0807

Alternate gene names: 150007456

Gene position: 954559-952790 (Counterclockwise)

Preceding gene: 150007457

Following gene: 150007455

Centisome position: 19.84

GC content: 41.13

Gene sequence:

>1770_bases
ATGGTAAAGATAGATGGTGAGAAAAGACACCGGATACCGTTTAGCCAACGGCTTTTCTGGTCGGTCTTTTTTATGTTCTT
GGGCTTTACGGTCTGTTTCCTGCTATTCCAATATCAGCGGGAAAGGGAGTTCGCGCAAGAAAAGTTGAACAATGTGTTGA
GTAACTATAATTACCAATTATTCCGCAAATGCCAACAAAGTACGGACATCAACAAGACCGTAATAAGTTTCATGGACGAC
ATCCCTCAAAAGGATTTGCGGGTAACCATTATAGATCCGTCCGGCGACGTATTATTTGATAATAGCGGGACGGATGAGTT
CAATAATCATAACGATCGAAGCGAGGTACGCAAAGCCCGATTATATAATGAAGGGTTCGCTATCCGTTCCTCGGAATCTA
CGGGAAAAAGGTATTTCTATTCGGCATCGAATATAGGAGGTTATATTTACCGCTCAGCCCTGCCCTATGATCCATATGTA
AGAGGGATATTGACGGTAAACAAGGACTTCATTTATTTCATGGCATTGATGACCTTGATTTTCTTCTTTGTCCTTTCCCG
TTTTACTTTCAGCATAGGTAAAACGATATCCAAACTAAGGGATTTCGCCTTAAACGTAGAGAAAGATCGAATGCCTGCGG
TCGATTATGTTTTCCCGAATGATGAACTAGGTGATATCTCACAGAATATCGTAACCTTATACCATCGGCAGCAGAAAGCG
AAAAACGAGTTATCCATGGAACGGGAAAAGCTTATCAAACATTTCCAATATTCCAAGGAAGGATTCGCTATGTTTACGAG
TGAAGGGCGGGAGATTCTTTCTAACATCCTATTCATTCAATTCATAAATGTCATATCCGACACCCAGATCCACCAAGTGG
AAGACGTTACTGATATAGCCGAATTAGAACCAATCCGTACCTTCTTGAATAAGAATATCCGGAATCTGAATCGGAAAAAG
AAAGTATTAAGAGAGTCCGTGACTATTGACAAGAACGGTAAAATATTCTTGATCGAATGTATTTTATTCCTCGATAATAG
TTATGAGATCTCTATTAATGATATATCCCGTCAAGAAGAAGAAAGCCGGATGAAACGACAGCTTACGCAGAACGTCTCTC
ACGAGCTGAAAACACCGGTCAGCAGCATTCAAGGGTATTTGGAAACAATCCTATCCAACCCAGATTTGAGTCCGGACAAA
CGTCAATTTTTCTTGGAACGTTGTTATTCCCAAAGTACCCGCCTTACAGGATTATTACGAGATATTTCCGTATTAAACAG
ACTTGACGAGGCATCCGAGATGTTCGACCTCACGGAAGTAAATATCACGAAGCTTATCGCCGAGATACAAAAAGAATGCT
CCCAAGATATGGAAGAAAAACACATCACGTCGGAAATTATCCTCCCGGGAGATCCGACCGTGTTCGGGAATAACTCCCTA
CTCTATTCCATATTCCGGAATCTATATGACAACGCGATCGCTTATGCGGGAGAAAACATAAAGATTACCGTCAACTGCTA
TAAAGAAGATCCTAAATATTATTACTTTAGCTTCTCCGATAATGGAGTGGGTATCCCGGAAGAACATATCAATCGCATAT
TCGAGCGCTTCTACCGGGTAGACAAGGGACGCAGTCGTAAGATCGGAGGAACCGGATTAGGATTATCTATCGTTAAAAAC
GGGGTTAATTTTCATAAAGGACAAATATCGGCGAAGAGCAGTCCGGGAAAAGGGGTTACTTTTTTCTTCACTTTGAAAAA
GAAACTATAA

Upstream 100 bases:

>100_bases
CATCACCCGGTTACGTAAGAAAATAGGTCCTTATGGAAAGAACATCGTAACTCGCTTAGGTTTCGGTTATTGTTTTGAAT
GCTAATATTGTCGCTGAATC

Downstream 100 bases:

>100_bases
GGCAGACCTCGAAAATTCCATAACATACGCTTGATATTTAATATTAAAATGTATTTTTGTATTGAACATCATACAATATC
ATGAGAAATACCTATTTAGT

Product: two-component system sensor histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 589; Mature: 589

Protein sequence:

>589_residues
MVKIDGEKRHRIPFSQRLFWSVFFMFLGFTVCFLLFQYQREREFAQEKLNNVLSNYNYQLFRKCQQSTDINKTVISFMDD
IPQKDLRVTIIDPSGDVLFDNSGTDEFNNHNDRSEVRKARLYNEGFAIRSSESTGKRYFYSASNIGGYIYRSALPYDPYV
RGILTVNKDFIYFMALMTLIFFFVLSRFTFSIGKTISKLRDFALNVEKDRMPAVDYVFPNDELGDISQNIVTLYHRQQKA
KNELSMEREKLIKHFQYSKEGFAMFTSEGREILSNILFIQFINVISDTQIHQVEDVTDIAELEPIRTFLNKNIRNLNRKK
KVLRESVTIDKNGKIFLIECILFLDNSYEISINDISRQEEESRMKRQLTQNVSHELKTPVSSIQGYLETILSNPDLSPDK
RQFFLERCYSQSTRLTGLLRDISVLNRLDEASEMFDLTEVNITKLIAEIQKECSQDMEEKHITSEIILPGDPTVFGNNSL
LYSIFRNLYDNAIAYAGENIKITVNCYKEDPKYYYFSFSDNGVGIPEEHINRIFERFYRVDKGRSRKIGGTGLGLSIVKN
GVNFHKGQISAKSSPGKGVTFFFTLKKKL

Sequences:

>Translated_589_residues
MVKIDGEKRHRIPFSQRLFWSVFFMFLGFTVCFLLFQYQREREFAQEKLNNVLSNYNYQLFRKCQQSTDINKTVISFMDD
IPQKDLRVTIIDPSGDVLFDNSGTDEFNNHNDRSEVRKARLYNEGFAIRSSESTGKRYFYSASNIGGYIYRSALPYDPYV
RGILTVNKDFIYFMALMTLIFFFVLSRFTFSIGKTISKLRDFALNVEKDRMPAVDYVFPNDELGDISQNIVTLYHRQQKA
KNELSMEREKLIKHFQYSKEGFAMFTSEGREILSNILFIQFINVISDTQIHQVEDVTDIAELEPIRTFLNKNIRNLNRKK
KVLRESVTIDKNGKIFLIECILFLDNSYEISINDISRQEEESRMKRQLTQNVSHELKTPVSSIQGYLETILSNPDLSPDK
RQFFLERCYSQSTRLTGLLRDISVLNRLDEASEMFDLTEVNITKLIAEIQKECSQDMEEKHITSEIILPGDPTVFGNNSL
LYSIFRNLYDNAIAYAGENIKITVNCYKEDPKYYYFSFSDNGVGIPEEHINRIFERFYRVDKGRSRKIGGTGLGLSIVKN
GVNFHKGQISAKSSPGKGVTFFFTLKKKL
>Mature_589_residues
MVKIDGEKRHRIPFSQRLFWSVFFMFLGFTVCFLLFQYQREREFAQEKLNNVLSNYNYQLFRKCQQSTDINKTVISFMDD
IPQKDLRVTIIDPSGDVLFDNSGTDEFNNHNDRSEVRKARLYNEGFAIRSSESTGKRYFYSASNIGGYIYRSALPYDPYV
RGILTVNKDFIYFMALMTLIFFFVLSRFTFSIGKTISKLRDFALNVEKDRMPAVDYVFPNDELGDISQNIVTLYHRQQKA
KNELSMEREKLIKHFQYSKEGFAMFTSEGREILSNILFIQFINVISDTQIHQVEDVTDIAELEPIRTFLNKNIRNLNRKK
KVLRESVTIDKNGKIFLIECILFLDNSYEISINDISRQEEESRMKRQLTQNVSHELKTPVSSIQGYLETILSNPDLSPDK
RQFFLERCYSQSTRLTGLLRDISVLNRLDEASEMFDLTEVNITKLIAEIQKECSQDMEEKHITSEIILPGDPTVFGNNSL
LYSIFRNLYDNAIAYAGENIKITVNCYKEDPKYYYFSFSDNGVGIPEEHINRIFERFYRVDKGRSRKIGGTGLGLSIVKN
GVNFHKGQISAKSSPGKGVTFFFTLKKKL

Specific function: Member of the two-component regulatory system phoP/phoR involved in the alkaline phosphatase genes regulation. PhoR may function as a membrane-associated protein kinase that phosphorylates phoP in response to environmental signals [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1786600, Length=257, Percent_Identity=33.852140077821, Blast_Score=150, Evalue=3e-37,
Organism=Escherichia coli, GI1788393, Length=230, Percent_Identity=30, Blast_Score=114, Evalue=2e-26,
Organism=Escherichia coli, GI1790346, Length=222, Percent_Identity=28.8288288288288, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI48994928, Length=230, Percent_Identity=26.9565217391304, Blast_Score=96, Evalue=5e-21,
Organism=Escherichia coli, GI1789149, Length=234, Percent_Identity=29.0598290598291, Blast_Score=93, Evalue=4e-20,
Organism=Escherichia coli, GI1790861, Length=221, Percent_Identity=28.0542986425339, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI1788713, Length=237, Percent_Identity=27.8481012658228, Blast_Score=89, Evalue=8e-19,
Organism=Escherichia coli, GI1786783, Length=246, Percent_Identity=28.4552845528455, Blast_Score=86, Evalue=5e-18,
Organism=Escherichia coli, GI145693157, Length=398, Percent_Identity=24.6231155778894, Blast_Score=79, Evalue=9e-16,
Organism=Escherichia coli, GI1790436, Length=253, Percent_Identity=28.8537549407115, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI1786912, Length=247, Percent_Identity=29.1497975708502, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI1790551, Length=228, Percent_Identity=28.0701754385965, Blast_Score=78, Evalue=2e-15,
Organism=Escherichia coli, GI87082128, Length=223, Percent_Identity=26.0089686098655, Blast_Score=76, Evalue=5e-15,
Organism=Escherichia coli, GI1787894, Length=220, Percent_Identity=26.3636363636364, Blast_Score=72, Evalue=8e-14,
Organism=Escherichia coli, GI1789403, Length=205, Percent_Identity=30.2439024390244, Blast_Score=69, Evalue=7e-13,
Organism=Escherichia coli, GI1788549, Length=246, Percent_Identity=24.390243902439, Blast_Score=69, Evalue=1e-12,
Organism=Escherichia coli, GI1788279, Length=201, Percent_Identity=26.3681592039801, Blast_Score=63, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 68553; Mature: 68553

Theoretical pI: Translated: 8.47; Mature: 8.47

Prosite motif: PS50109 HIS_KIN ; PS00139 THIOL_PROTEASE_CYS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVKIDGEKRHRIPFSQRLFWSVFFMFLGFTVCFLLFQYQREREFAQEKLNNVLSNYNYQL
CEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
FRKCQQSTDINKTVISFMDDIPQKDLRVTIIDPSGDVLFDNSGTDEFNNHNDRSEVRKAR
HHHHHHCCCHHHHHHHHHHCCCCCCCEEEEECCCCCEEECCCCCCCCCCCCCHHHHHHHH
LYNEGFAIRSSESTGKRYFYSASNIGGYIYRSALPYDPYVRGILTVNKDFIYFMALMTLI
HHCCCCEEECCCCCCCEEEEECCCCCCHHEECCCCCCHHHHHHEEECHHHHHHHHHHHHH
FFFVLSRFTFSIGKTISKLRDFALNVEKDRMPAVDYVFPNDELGDISQNIVTLYHRQQKA
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHH
KNELSMEREKLIKHFQYSKEGFAMFTSEGREILSNILFIQFINVISDTQIHQVEDVTDIA
HHHHHHHHHHHHHHHHCCCCCCEEEHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
ELEPIRTFLNKNIRNLNRKKKVLRESVTIDKNGKIFLIECILFLDNSYEISINDISRQEE
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEHHHCCCCEEEEHHHHHHHH
ESRMKRQLTQNVSHELKTPVSSIQGYLETILSNPDLSPDKRQFFLERCYSQSTRLTGLLR
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCHHHHHHHHH
DISVLNRLDEASEMFDLTEVNITKLIAEIQKECSQDMEEKHITSEIILPGDPTVFGNNSL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCEECCCHH
LYSIFRNLYDNAIAYAGENIKITVNCYKEDPKYYYFSFSDNGVGIPEEHINRIFERFYRV
HHHHHHHHHHHHHHCCCCCEEEEEEEEECCCCEEEEEECCCCCCCCHHHHHHHHHHHHHH
DKGRSRKIGGTGLGLSIVKNGVNFHKGQISAKSSPGKGVTFFFTLKKKL
CCCCCCCCCCCCCHHHHHHCCCCCCCCEEECCCCCCCCEEEEEEEECCC
>Mature Secondary Structure
MVKIDGEKRHRIPFSQRLFWSVFFMFLGFTVCFLLFQYQREREFAQEKLNNVLSNYNYQL
CEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
FRKCQQSTDINKTVISFMDDIPQKDLRVTIIDPSGDVLFDNSGTDEFNNHNDRSEVRKAR
HHHHHHCCCHHHHHHHHHHCCCCCCCEEEEECCCCCEEECCCCCCCCCCCCCHHHHHHHH
LYNEGFAIRSSESTGKRYFYSASNIGGYIYRSALPYDPYVRGILTVNKDFIYFMALMTLI
HHCCCCEEECCCCCCCEEEEECCCCCCHHEECCCCCCHHHHHHEEECHHHHHHHHHHHHH
FFFVLSRFTFSIGKTISKLRDFALNVEKDRMPAVDYVFPNDELGDISQNIVTLYHRQQKA
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHH
KNELSMEREKLIKHFQYSKEGFAMFTSEGREILSNILFIQFINVISDTQIHQVEDVTDIA
HHHHHHHHHHHHHHHHCCCCCCEEEHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
ELEPIRTFLNKNIRNLNRKKKVLRESVTIDKNGKIFLIECILFLDNSYEISINDISRQEE
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEHHHCCCCEEEEHHHHHHHH
ESRMKRQLTQNVSHELKTPVSSIQGYLETILSNPDLSPDKRQFFLERCYSQSTRLTGLLR
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCHHHHHHHHH
DISVLNRLDEASEMFDLTEVNITKLIAEIQKECSQDMEEKHITSEIILPGDPTVFGNNSL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCEECCCHH
LYSIFRNLYDNAIAYAGENIKITVNCYKEDPKYYYFSFSDNGVGIPEEHINRIFERFYRV
HHHHHHHHHHHHHHCCCCCEEEEEEEEECCCCEEEEEECCCCCCCCHHHHHHHHHHHHHH
DKGRSRKIGGTGLGLSIVKNGVNFHKGQISAKSSPGKGVTFFFTLKKKL
CCCCCCCCCCCCCHHHHHHCCCCCCCCEEECCCCCCCCEEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 3142862; 9387221; 9384377 [H]