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The map label for this gene is arlR [H]

Identifier: 150007457

GI number: 150007457

Start: 954575

End: 955261

Strand: Reverse

Name: arlR [H]

Synonym: BDI_0808

Alternate gene names: 150007457

Gene position: 955261-954575 (Counterclockwise)

Preceding gene: 150007458

Following gene: 150007456

Centisome position: 19.85

GC content: 42.5

Gene sequence:

>687_bases
ATGGCAACAACTCGTATTCTTGTAGTGGATGATGAAGAGGATTTGTGTGAGATCCTTAAATTCAACTTAGAAATAGAAGG
TTATGAAGTAGATACCGCCTATAGTGCGGAAGAGGCATTGAAAAAGGATCTGACCGTTTACAATTTATTATTGTTGGATG
TCATGATGGGAGAAATCTCCGGTTTCAAGATGGCACGTATCCTGCGACAAGATGAGAAGACGGCCAATACCCCTATCATC
TTCCTCACGGCCAAAGATACGGAGAACGATATGCTCACAGGGTTCAATCTCGGGGCGGACGACTATATCTCCAAGCCTTT
CTCCATCCGCCAAGTGATAGCGCGTGTTAAGGCCGTACTAAGAAGAACTTCCGAGAAATCAAAAGAAAAAGAGATTGAGA
AACTCGAGTATGAGACATTAGCTCTTGATACGAAACGCATCAAGGCTACGGTAGACGGGGTGGAAGTTCCATTGACCAAA
AAAGAGTTTGAGATACTAAAACTTCTATTGGAAAATAAAGGGAACGTCTTCTCCAGAGAGGAAATACTGTCTCGCATCTG
GAAAGACGAGGTATATGTTCTAGACCGTACCATCGATGTCAACATCACCCGGTTACGTAAGAAAATAGGTCCTTATGGAA
AGAACATCGTAACTCGCTTAGGTTTCGGTTATTGTTTTGAATGCTAA

Upstream 100 bases:

>100_bases
TATTTCATTTCTCCGAAATAAGAATATCCGTTCTTTGCCAAAAATAATTATATTTGTATATGGAGAGCCGTAAGGCACTC
TTTTAAAAACAGAACAGCTT

Downstream 100 bases:

>100_bases
TATTGTCGCTGAATCATGGTAAAGATAGATGGTGAGAAAAGACACCGGATACCGTTTAGCCAACGGCTTTTCTGGTCGGT
CTTTTTTATGTTCTTGGGCT

Product: two-component system response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 228; Mature: 227

Protein sequence:

>228_residues
MATTRILVVDDEEDLCEILKFNLEIEGYEVDTAYSAEEALKKDLTVYNLLLLDVMMGEISGFKMARILRQDEKTANTPII
FLTAKDTENDMLTGFNLGADDYISKPFSIRQVIARVKAVLRRTSEKSKEKEIEKLEYETLALDTKRIKATVDGVEVPLTK
KEFEILKLLLENKGNVFSREEILSRIWKDEVYVLDRTIDVNITRLRKKIGPYGKNIVTRLGFGYCFEC

Sequences:

>Translated_228_residues
MATTRILVVDDEEDLCEILKFNLEIEGYEVDTAYSAEEALKKDLTVYNLLLLDVMMGEISGFKMARILRQDEKTANTPII
FLTAKDTENDMLTGFNLGADDYISKPFSIRQVIARVKAVLRRTSEKSKEKEIEKLEYETLALDTKRIKATVDGVEVPLTK
KEFEILKLLLENKGNVFSREEILSRIWKDEVYVLDRTIDVNITRLRKKIGPYGKNIVTRLGFGYCFEC
>Mature_227_residues
ATTRILVVDDEEDLCEILKFNLEIEGYEVDTAYSAEEALKKDLTVYNLLLLDVMMGEISGFKMARILRQDEKTANTPIIF
LTAKDTENDMLTGFNLGADDYISKPFSIRQVIARVKAVLRRTSEKSKEKEIEKLEYETLALDTKRIKATVDGVEVPLTKK
EFEILKLLLENKGNVFSREEILSRIWKDEVYVLDRTIDVNITRLRKKIGPYGKNIVTRLGFGYCFEC

Specific function: Member of the two-component regulatory system ArlS/ArlR involved in the regulation of adhesion, autolysis, multidrug resistance and virulence [H]

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786599, Length=227, Percent_Identity=37.8854625550661, Blast_Score=147, Evalue=5e-37,
Organism=Escherichia coli, GI2367329, Length=210, Percent_Identity=39.5238095238095, Blast_Score=137, Evalue=4e-34,
Organism=Escherichia coli, GI1788394, Length=209, Percent_Identity=38.2775119617225, Blast_Score=130, Evalue=9e-32,
Organism=Escherichia coli, GI1790860, Length=232, Percent_Identity=34.051724137931, Blast_Score=129, Evalue=1e-31,
Organism=Escherichia coli, GI87082012, Length=228, Percent_Identity=32.8947368421053, Blast_Score=122, Evalue=3e-29,
Organism=Escherichia coli, GI1789809, Length=232, Percent_Identity=34.051724137931, Blast_Score=119, Evalue=2e-28,
Organism=Escherichia coli, GI1786784, Length=229, Percent_Identity=34.4978165938865, Blast_Score=116, Evalue=1e-27,
Organism=Escherichia coli, GI1790863, Length=236, Percent_Identity=34.3220338983051, Blast_Score=114, Evalue=7e-27,
Organism=Escherichia coli, GI1787375, Length=227, Percent_Identity=30.8370044052863, Blast_Score=109, Evalue=2e-25,
Organism=Escherichia coli, GI1790552, Length=227, Percent_Identity=33.4801762114537, Blast_Score=108, Evalue=3e-25,
Organism=Escherichia coli, GI1789402, Length=225, Percent_Identity=32, Blast_Score=107, Evalue=8e-25,
Organism=Escherichia coli, GI1786911, Length=227, Percent_Identity=30.3964757709251, Blast_Score=106, Evalue=2e-24,
Organism=Escherichia coli, GI1787229, Length=226, Percent_Identity=30.0884955752212, Blast_Score=92, Evalue=3e-20,
Organism=Escherichia coli, GI145693140, Length=192, Percent_Identity=29.1666666666667, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1788550, Length=136, Percent_Identity=30.8823529411765, Blast_Score=62, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 26235; Mature: 26104

Theoretical pI: Translated: 4.89; Mature: 4.89

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATTRILVVDDEEDLCEILKFNLEIEGYEVDTAYSAEEALKKDLTVYNLLLLDVMMGEIS
CCCEEEEEEECCHHHHHHHHHCCEEECEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHC
GFKMARILRQDEKTANTPIIFLTAKDTENDMLTGFNLGADDYISKPFSIRQVIARVKAVL
HHHHHHHHHHCCCCCCCCEEEEEECCCCCCEEEECCCCCHHHHCCCHHHHHHHHHHHHHH
RRTSEKSKEKEIEKLEYETLALDTKRIKATVDGVEVPLTKKEFEILKLLLENKGNVFSRE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCEECCCCHHHHHHHHHHHHCCCCCCCHH
EILSRIWKDEVYVLDRTIDVNITRLRKKIGPYGKNIVTRLGFGYCFEC
HHHHHHHCCCEEEEEEEECCHHHHHHHHHCCCCHHHHHHHCCCEEECC
>Mature Secondary Structure 
ATTRILVVDDEEDLCEILKFNLEIEGYEVDTAYSAEEALKKDLTVYNLLLLDVMMGEIS
CCEEEEEEECCHHHHHHHHHCCEEECEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHC
GFKMARILRQDEKTANTPIIFLTAKDTENDMLTGFNLGADDYISKPFSIRQVIARVKAVL
HHHHHHHHHHCCCCCCCCEEEEEECCCCCCEEEECCCCCHHHHCCCHHHHHHHHHHHHHH
RRTSEKSKEKEIEKLEYETLALDTKRIKATVDGVEVPLTKKEFEILKLLLENKGNVFSRE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCEECCCCHHHHHHHHHHHHCCCCCCCHH
EILSRIWKDEVYVLDRTIDVNITRLRKKIGPYGKNIVTRLGFGYCFEC
HHHHHHHCCCEEEEEEEECCHHHHHHHHHCCCCHHHHHHHCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA