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The map label for this gene is emrK [H]

Identifier: 150007333

GI number: 150007333

Start: 812344

End: 813414

Strand: Reverse

Name: emrK [H]

Synonym: BDI_0683

Alternate gene names: 150007333

Gene position: 813414-812344 (Counterclockwise)

Preceding gene: 150007334

Following gene: 150007332

Centisome position: 16.91

GC content: 48.37

Gene sequence:

>1071_bases
ATGGCAAACGAATTAAAAGAGAAACATCAAAGACTAAAGAAAGTAAGGACACGGAATATAGTATTAAACTCCATATGTAT
CCTTTTAGCCGGTTCCGGCATTTGGTGGACAGCCAATTATTTCTGGCGTTACATCAATTATGAGGTGACAAACGATGCCT
TTGTGGACCAATATATCGCCCCACTAAATATACGTGCCTCCGGCTACATAAAAGAGGTCCGTTTCAAGGAACACCAGTAC
GTTCACCAAGGGGACACACTTCTCATACTGGACGATCGGGAATATCGGATCAAGTTAAAAGAGGCAGAGGCCGCGTTGAT
CGATGCCCAAGGATCACAAGACGTACTTCGTTCCGGTATCGAGACCTCCCATACGAACATCGCCGTACAAGACGCCAACA
TCGCCGAAGCTAAAGCCAAGCTTTGGCAACTGGAACAGGATTATCACCGATTTGAGCGGCTGCTGAAAGAAGAATCGGTC
CCCGAGCAACAATACGAGCAATCCAAAGCCGCTTTCGAGGCGGCGCAAGCCCGATATCAGGCGTTGGTGGAACAAAAGAA
AGCCGCTTTCTCCCAATTCACCGAAACCAGCAAGAAGACAACAGGAGCCGAGGCGGCGATCTTACGAAAAGAAGCGGATC
TGGATTTAGCGAGGTTAAACCTTTCCTATACCGTTATAACCGCCCCTTACGACGGTCATGTAGGCAGACGGACCTTAGAG
CCCGGACAATACGTGCAAGCCGGACAAACGATATCCTACCTCGTACGAGATAAAGACAAATGGATCACGGCCAATTACAA
GGAGACCCAGATCCCCCACATCTATATCGGGCAAAAAGTACGTATCAAGGTAGACGCGTTGCCGGGAAAGATATTCAACG
GGGAGGTAACCGCAATCTCCGACGCCACAGGCTCCAAATACTCATTGGTCCCGACCGACAATTCCGCCGGAAACTTCGTC
AAGGTACAACAACGTATCCCGGTACGGATAGACTTGGAAAATCTATCGCAAGAAGATACGCAATACTTAAGAGCAGGCAT
GATGGTTGAAACAGAAGCCTTACGCAAATGA

Upstream 100 bases:

>100_bases
CAACGCGGAGCTACAGCTCACGAATGCCCGTACCCACGTGATTTACACTTACTATCAACTACAGAAGGCTTGCGGCCGTC
TCTAAAAAGAAACAACGACT

Downstream 100 bases:

>100_bases
TCACGATGAAAGAGCTTGGGGCACCGATCCGCCAATGGGTGCCGGACTGGTTAGGATTGATTTGCATCTTCATCGTTATC
CTTCCGGTTACGATGCTAAA

Product: putative multidrug resistance protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 356; Mature: 355

Protein sequence:

>356_residues
MANELKEKHQRLKKVRTRNIVLNSICILLAGSGIWWTANYFWRYINYEVTNDAFVDQYIAPLNIRASGYIKEVRFKEHQY
VHQGDTLLILDDREYRIKLKEAEAALIDAQGSQDVLRSGIETSHTNIAVQDANIAEAKAKLWQLEQDYHRFERLLKEESV
PEQQYEQSKAAFEAAQARYQALVEQKKAAFSQFTETSKKTTGAEAAILRKEADLDLARLNLSYTVITAPYDGHVGRRTLE
PGQYVQAGQTISYLVRDKDKWITANYKETQIPHIYIGQKVRIKVDALPGKIFNGEVTAISDATGSKYSLVPTDNSAGNFV
KVQQRIPVRIDLENLSQEDTQYLRAGMMVETEALRK

Sequences:

>Translated_356_residues
MANELKEKHQRLKKVRTRNIVLNSICILLAGSGIWWTANYFWRYINYEVTNDAFVDQYIAPLNIRASGYIKEVRFKEHQY
VHQGDTLLILDDREYRIKLKEAEAALIDAQGSQDVLRSGIETSHTNIAVQDANIAEAKAKLWQLEQDYHRFERLLKEESV
PEQQYEQSKAAFEAAQARYQALVEQKKAAFSQFTETSKKTTGAEAAILRKEADLDLARLNLSYTVITAPYDGHVGRRTLE
PGQYVQAGQTISYLVRDKDKWITANYKETQIPHIYIGQKVRIKVDALPGKIFNGEVTAISDATGSKYSLVPTDNSAGNFV
KVQQRIPVRIDLENLSQEDTQYLRAGMMVETEALRK
>Mature_355_residues
ANELKEKHQRLKKVRTRNIVLNSICILLAGSGIWWTANYFWRYINYEVTNDAFVDQYIAPLNIRASGYIKEVRFKEHQYV
HQGDTLLILDDREYRIKLKEAEAALIDAQGSQDVLRSGIETSHTNIAVQDANIAEAKAKLWQLEQDYHRFERLLKEESVP
EQQYEQSKAAFEAAQARYQALVEQKKAAFSQFTETSKKTTGAEAAILRKEADLDLARLNLSYTVITAPYDGHVGRRTLEP
GQYVQAGQTISYLVRDKDKWITANYKETQIPHIYIGQKVRIKVDALPGKIFNGEVTAISDATGSKYSLVPTDNSAGNFVK
VQQRIPVRIDLENLSQEDTQYLRAGMMVETEALRK

Specific function: Unknown

COG id: COG1566

COG function: function code V; Multidrug resistance efflux pump

Gene ontology:

Cell location: Cell inner membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI1788711, Length=293, Percent_Identity=32.7645051194539, Blast_Score=139, Evalue=4e-34,
Organism=Escherichia coli, GI1789041, Length=337, Percent_Identity=29.673590504451, Blast_Score=130, Evalue=1e-31,
Organism=Escherichia coli, GI1790519, Length=314, Percent_Identity=28.0254777070064, Blast_Score=115, Evalue=3e-27,
Organism=Escherichia coli, GI1790024, Length=272, Percent_Identity=24.2647058823529, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI1790012, Length=252, Percent_Identity=24.6031746031746, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI1787013, Length=246, Percent_Identity=25.609756097561, Blast_Score=62, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005694
- InterPro:   IPR006143 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 40651; Mature: 40520

Theoretical pI: Translated: 8.31; Mature: 8.31

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
0.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MANELKEKHQRLKKVRTRNIVLNSICILLAGSGIWWTANYFWRYINYEVTNDAFVDQYIA
CCHHHHHHHHHHHHHHHHHHHHHHEEEHEECCCCEEEHEEEEEEEEEEECCCHHHHHHHC
PLNIRASGYIKEVRFKEHQYVHQGDTLLILDDREYRIKLKEAEAALIDAQGSQDVLRSGI
CEEEECCCHHHHHHHHHHHHEECCCEEEEECCCCEEEEEEECCEEEEECCCCHHHHHCCC
ETSHTNIAVQDANIAEAKAKLWQLEQDYHRFERLLKEESVPEQQYEQSKAAFEAAQARYQ
CCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
ALVEQKKAAFSQFTETSKKTTGAEAAILRKEADLDLARLNLSYTVITAPYDGHVGRRTLE
HHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCEEEEEEEEEEEEECCCCCCCCCCCCC
PGQYVQAGQTISYLVRDKDKWITANYKETQIPHIYIGQKVRIKVDALPGKIFNGEVTAIS
CCCHHHCCCCEEEEEECCCCEEECCCCCCCCCEEEECCEEEEEEECCCCEEECCEEEEEE
DATGSKYSLVPTDNSAGNFVKVQQRIPVRIDLENLSQEDTQYLRAGMMVETEALRK
CCCCCEEEEEECCCCCCCEEEEEECCCEEEEHHHCCHHHHHHHHHCCEEEHHHHCC
>Mature Secondary Structure 
ANELKEKHQRLKKVRTRNIVLNSICILLAGSGIWWTANYFWRYINYEVTNDAFVDQYIA
CHHHHHHHHHHHHHHHHHHHHHHEEEHEECCCCEEEHEEEEEEEEEEECCCHHHHHHHC
PLNIRASGYIKEVRFKEHQYVHQGDTLLILDDREYRIKLKEAEAALIDAQGSQDVLRSGI
CEEEECCCHHHHHHHHHHHHEECCCEEEEECCCCEEEEEEECCEEEEECCCCHHHHHCCC
ETSHTNIAVQDANIAEAKAKLWQLEQDYHRFERLLKEESVPEQQYEQSKAAFEAAQARYQ
CCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
ALVEQKKAAFSQFTETSKKTTGAEAAILRKEADLDLARLNLSYTVITAPYDGHVGRRTLE
HHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCEEEEEEEEEEEEECCCCCCCCCCCCC
PGQYVQAGQTISYLVRDKDKWITANYKETQIPHIYIGQKVRIKVDALPGKIFNGEVTAIS
CCCHHHCCCCEEEEEECCCCEEECCCCCCCCCEEEECCEEEEEEECCCCEEECCEEEEEE
DATGSKYSLVPTDNSAGNFVKVQQRIPVRIDLENLSQEDTQYLRAGMMVETEALRK
CCCCCEEEEEECCCCCCCEEEEEECCCEEEEHHHCCHHHHHHHHHCCEEEHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9205837; 9278503 [H]