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The map label for this gene is htpG [H]

Identifier: 150007331

GI number: 150007331

Start: 808518

End: 810572

Strand: Reverse

Name: htpG [H]

Synonym: BDI_0681

Alternate gene names: 150007331

Gene position: 810572-808518 (Counterclockwise)

Preceding gene: 150007332

Following gene: 150007329

Centisome position: 16.85

GC content: 45.4

Gene sequence:

>2055_bases
ATGAGCAGTAAACAAGGTAACATCGGAGTAACATCGGAAAACATCTTTCCGATTATCAAGAAGTTCTTATACAGTGATCA
CGAAATCTTCCTTCGTGAACTTGTTTCTAATGCGGTAGACGCTACCCAGAAGTTAAAAACGCTTTCTTCCGTAGGCGAGT
TTAAAGGCGAACTCGGTGATTTGACCGTACAGGTTAAGTTCGATGACAAAACGATCACGATCTCTGACCGGGGTATCGGT
ATGACAGCCGAGGAGATCGATAAGTACATCAACCAGATCGCTTTCTCCGGCGCCGAGGAGTTCGTTGAGAAATACAAGAA
CGACGCCGCTTCTATCATCGGTCACTTCGGTCTTGGTTTCTACTCCTCTTTCATGGTTTCCAAGAAAGTAGAGATCGTGA
CGAAATCGTACAAAGAAGGCGCTGTTCCCATGAAATGGAGCTGCGACGGTACACCGGAATACTCCTTGGAGGAAACGACG
AAAGAGGATCGTGGTACCGATATTATCCTGTATATAGACGACGAGAATAAAGATTTCTTGAACAAGGATAAGATCAATGG
CTTATTGACAAAATACTGCCGTTTCTTACCGGTTCCTATCGCATTCGGCAAGAAGCAAGAGTGGAAGGATGGCAAATATG
TAGATACGGACGAAGATAACGTAATCAACGACACCAAACCGGCATGGGTTCGCAAACCGGCCGATATGACCGACGAGGAT
TACAAGAAGTTCTATCGTGACTTATATCCTATGACGGATGAGCCGTTGTTCTGGATTCACTTGAACGTAGACTATCCGTT
CAACTTGACCGGTATCTTATATTTCCCTCGCATCAAGAGCAATATCGACTTGCATCGTAACAAGATCCAGTTATATTGCA
ACCAAGTATTCGTTACGGATTCCGTAGAGGGTATCGTTCCTGAGTTCTTGACATTATTGCATGGTGTATTGGATTCGCCG
GATATCCCGTTGAACGTATCCCGTTCCTATTTGCAAAGCGATCAGAACGTGAAGAAGATCTCCAACCACATCACGAAGAA
GGTGGCAGACCGCTTGGAAGAGATCTTCAAGAACGACCGCCCGCAGTTCGAGGAGAAATGGGATAGCTTGAAACTATTCA
TCCAATATGGTATGTTGACTGATGAGAAGTTCTACGACCGTGCGGTTAAGTTCGCCTTATTCAAGGACGTCGAAGGCAAA
TACTTCACTTTCGAGGAATACAAGAACTTAATCAAGGACAACCAGACAGACAAAGAGGGTAACTTAATCTATCTGTATAC
CACCAATAAAGACGAGCAATACAGCTATATACAAGCCGCAAAGGACAAAGGTTACAGCGTCTTGGAAATGGACGGACAAT
TGGATGTACACTTGATCGGACAATTGGAGCAGAAGTTCGAGAAGAGCCGCTTCGTTCGTGTGGATAGCGATACGATCGAT
AACCTGATCCGCAAGGAAGACTCGAATAAGGTAACCTTGAGCGAGGAGCAGAAAATGGCCATGCAGGAAGTATTCAAGAG
TCAGATGCCGAAATTGAACAAGACCGAGTTCTACGTAACATTCGAGGCATTGGGCGAAAACGCGAACCCTGTCATGTTGA
CACAAAGCGAGTATATGCGAAGAATGCGTGAGATGTCCGCTATGCAACCGGGTATGTCTTTCTATGGCGAGATGCCGGAT
AGCTTCAACTTCGTATTGAATACGGATCATCCGTTGATCAAGAAAGTATTAACTGAAGAGGAGCAAGCTTGCGACGAGAA
GTTAAAACCGATCCTTAGCGATATCAAAGGATGGGAGGCTCGTCAAGCCGACTTACGTGAGGCTCAAAGCAAAAAGAAAG
AAGATGAGATCACGGCGCAAGAGAAAGAGGATATGACCAACACCAACCATAAGCTGGATGAGCTTCGTGAGCAACGCAAC
CAAGTTCTCGCCGAGTACGCCGGTACGAACAAGACAGTTAGTCAGTTGATCGACCTTGCTTTGTTAGGAAACGGTATGCT
GAAGGGAGAGGCCTTAAGCCAATTCATCAAACGTAGCGTAGAACTGATCGGATAA

Upstream 100 bases:

>100_bases
ATTTTGGCATTCGTTTTGTATAGGAATAGGCGGATCTTGAGAATGATCAGGATCAGGAATACGCACAAAATAACAATAAA
AATAATAAGATATTCAGACT

Downstream 100 bases:

>100_bases
ACCAATCCTCACATATATAAAAAACCGTTCCTTCTCGGGGGAACGGTTTTTTTAGTTTCAGCCCACGACATCCTCGACCA
CTTTCCGCAACCTATCCAAG

Product: heat shock protein 90

Products: NA

Alternate protein names: Heat shock protein htpG; High temperature protein G [H]

Number of amino acids: Translated: 684; Mature: 683

Protein sequence:

>684_residues
MSSKQGNIGVTSENIFPIIKKFLYSDHEIFLRELVSNAVDATQKLKTLSSVGEFKGELGDLTVQVKFDDKTITISDRGIG
MTAEEIDKYINQIAFSGAEEFVEKYKNDAASIIGHFGLGFYSSFMVSKKVEIVTKSYKEGAVPMKWSCDGTPEYSLEETT
KEDRGTDIILYIDDENKDFLNKDKINGLLTKYCRFLPVPIAFGKKQEWKDGKYVDTDEDNVINDTKPAWVRKPADMTDED
YKKFYRDLYPMTDEPLFWIHLNVDYPFNLTGILYFPRIKSNIDLHRNKIQLYCNQVFVTDSVEGIVPEFLTLLHGVLDSP
DIPLNVSRSYLQSDQNVKKISNHITKKVADRLEEIFKNDRPQFEEKWDSLKLFIQYGMLTDEKFYDRAVKFALFKDVEGK
YFTFEEYKNLIKDNQTDKEGNLIYLYTTNKDEQYSYIQAAKDKGYSVLEMDGQLDVHLIGQLEQKFEKSRFVRVDSDTID
NLIRKEDSNKVTLSEEQKMAMQEVFKSQMPKLNKTEFYVTFEALGENANPVMLTQSEYMRRMREMSAMQPGMSFYGEMPD
SFNFVLNTDHPLIKKVLTEEEQACDEKLKPILSDIKGWEARQADLREAQSKKKEDEITAQEKEDMTNTNHKLDELREQRN
QVLAEYAGTNKTVSQLIDLALLGNGMLKGEALSQFIKRSVELIG

Sequences:

>Translated_684_residues
MSSKQGNIGVTSENIFPIIKKFLYSDHEIFLRELVSNAVDATQKLKTLSSVGEFKGELGDLTVQVKFDDKTITISDRGIG
MTAEEIDKYINQIAFSGAEEFVEKYKNDAASIIGHFGLGFYSSFMVSKKVEIVTKSYKEGAVPMKWSCDGTPEYSLEETT
KEDRGTDIILYIDDENKDFLNKDKINGLLTKYCRFLPVPIAFGKKQEWKDGKYVDTDEDNVINDTKPAWVRKPADMTDED
YKKFYRDLYPMTDEPLFWIHLNVDYPFNLTGILYFPRIKSNIDLHRNKIQLYCNQVFVTDSVEGIVPEFLTLLHGVLDSP
DIPLNVSRSYLQSDQNVKKISNHITKKVADRLEEIFKNDRPQFEEKWDSLKLFIQYGMLTDEKFYDRAVKFALFKDVEGK
YFTFEEYKNLIKDNQTDKEGNLIYLYTTNKDEQYSYIQAAKDKGYSVLEMDGQLDVHLIGQLEQKFEKSRFVRVDSDTID
NLIRKEDSNKVTLSEEQKMAMQEVFKSQMPKLNKTEFYVTFEALGENANPVMLTQSEYMRRMREMSAMQPGMSFYGEMPD
SFNFVLNTDHPLIKKVLTEEEQACDEKLKPILSDIKGWEARQADLREAQSKKKEDEITAQEKEDMTNTNHKLDELREQRN
QVLAEYAGTNKTVSQLIDLALLGNGMLKGEALSQFIKRSVELIG
>Mature_683_residues
SSKQGNIGVTSENIFPIIKKFLYSDHEIFLRELVSNAVDATQKLKTLSSVGEFKGELGDLTVQVKFDDKTITISDRGIGM
TAEEIDKYINQIAFSGAEEFVEKYKNDAASIIGHFGLGFYSSFMVSKKVEIVTKSYKEGAVPMKWSCDGTPEYSLEETTK
EDRGTDIILYIDDENKDFLNKDKINGLLTKYCRFLPVPIAFGKKQEWKDGKYVDTDEDNVINDTKPAWVRKPADMTDEDY
KKFYRDLYPMTDEPLFWIHLNVDYPFNLTGILYFPRIKSNIDLHRNKIQLYCNQVFVTDSVEGIVPEFLTLLHGVLDSPD
IPLNVSRSYLQSDQNVKKISNHITKKVADRLEEIFKNDRPQFEEKWDSLKLFIQYGMLTDEKFYDRAVKFALFKDVEGKY
FTFEEYKNLIKDNQTDKEGNLIYLYTTNKDEQYSYIQAAKDKGYSVLEMDGQLDVHLIGQLEQKFEKSRFVRVDSDTIDN
LIRKEDSNKVTLSEEQKMAMQEVFKSQMPKLNKTEFYVTFEALGENANPVMLTQSEYMRRMREMSAMQPGMSFYGEMPDS
FNFVLNTDHPLIKKVLTEEEQACDEKLKPILSDIKGWEARQADLREAQSKKKEDEITAQEKEDMTNTNHKLDELREQRNQ
VLAEYAGTNKTVSQLIDLALLGNGMLKGEALSQFIKRSVELIG

Specific function: Molecular chaperone. Has ATPase activity [H]

COG id: COG0326

COG function: function code O; Molecular chaperone, HSP90 family

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the heat shock protein 90 family [H]

Homologues:

Organism=Homo sapiens, GI155722983, Length=619, Percent_Identity=27.7867528271405, Blast_Score=225, Evalue=1e-58,
Organism=Homo sapiens, GI4507677, Length=649, Percent_Identity=27.5808936825886, Blast_Score=190, Evalue=5e-48,
Organism=Homo sapiens, GI20149594, Length=638, Percent_Identity=25.5485893416928, Blast_Score=184, Evalue=2e-46,
Organism=Homo sapiens, GI154146191, Length=378, Percent_Identity=25.3968253968254, Blast_Score=112, Evalue=1e-24,
Organism=Homo sapiens, GI153792590, Length=271, Percent_Identity=27.6752767527675, Blast_Score=111, Evalue=3e-24,
Organism=Escherichia coli, GI1786679, Length=591, Percent_Identity=31.3028764805415, Blast_Score=255, Evalue=6e-69,
Organism=Caenorhabditis elegans, GI17542208, Length=630, Percent_Identity=28.4126984126984, Blast_Score=209, Evalue=3e-54,
Organism=Caenorhabditis elegans, GI17559162, Length=614, Percent_Identity=27.3615635179153, Blast_Score=202, Evalue=5e-52,
Organism=Caenorhabditis elegans, GI115535205, Length=458, Percent_Identity=27.7292576419214, Blast_Score=197, Evalue=1e-50,
Organism=Caenorhabditis elegans, GI115535167, Length=396, Percent_Identity=29.040404040404, Blast_Score=193, Evalue=3e-49,
Organism=Saccharomyces cerevisiae, GI6323840, Length=517, Percent_Identity=27.6595744680851, Blast_Score=192, Evalue=1e-49,
Organism=Saccharomyces cerevisiae, GI6325016, Length=265, Percent_Identity=29.4339622641509, Blast_Score=120, Evalue=8e-28,
Organism=Drosophila melanogaster, GI24586016, Length=604, Percent_Identity=29.1390728476821, Blast_Score=245, Evalue=7e-65,
Organism=Drosophila melanogaster, GI21357739, Length=516, Percent_Identity=30.2325581395349, Blast_Score=218, Evalue=1e-56,
Organism=Drosophila melanogaster, GI17647529, Length=625, Percent_Identity=27.52, Blast_Score=212, Evalue=7e-55,

Paralogues:

None

Copy number: 640 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 2419 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR019805
- InterPro:   IPR001404
- InterPro:   IPR020575
- InterPro:   IPR020568 [H]

Pfam domain/function: PF02518 HATPase_c; PF00183 HSP90 [H]

EC number: NA

Molecular weight: Translated: 79090; Mature: 78958

Theoretical pI: Translated: 4.81; Mature: 4.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSKQGNIGVTSENIFPIIKKFLYSDHEIFLRELVSNAVDATQKLKTLSSVGEFKGELGD
CCCCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
LTVQVKFDDKTITISDRGIGMTAEEIDKYINQIAFSGAEEFVEKYKNDAASIIGHFGLGF
EEEEEEECCEEEEEECCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
YSSFMVSKKVEIVTKSYKEGAVPMKWSCDGTPEYSLEETTKEDRGTDIILYIDDENKDFL
HHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCCCCHHHHHHHCCCCEEEEEEECCCCCCC
NKDKINGLLTKYCRFLPVPIAFGKKQEWKDGKYVDTDEDNVINDTKPAWVRKPADMTDED
CHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHCCCCCCCCHHH
YKKFYRDLYPMTDEPLFWIHLNVDYPFNLTGILYFPRIKSNIDLHRNKIQLYCNQVFVTD
HHHHHHHHCCCCCCCEEEEEEEECCCCCCEEEEEECCCCCCCHHHHHHEEEEEEEEEEEC
SVEGIVPEFLTLLHGVLDSPDIPLNVSRSYLQSDQNVKKISNHITKKVADRLEEIFKNDR
CHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCC
PQFEEKWDSLKLFIQYGMLTDEKFYDRAVKFALFKDVEGKYFTFEEYKNLIKDNQTDKEG
CCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHCCCCCCCCC
NLIYLYTTNKDEQYSYIQAAKDKGYSVLEMDGQLDVHLIGQLEQKFEKSRFVRVDSDTID
CEEEEEECCCCCHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHCEEEECHHHHH
NLIRKEDSNKVTLSEEQKMAMQEVFKSQMPKLNKTEFYVTFEALGENANPVMLTQSEYMR
HHHHCCCCCCEEECHHHHHHHHHHHHHHCCCCCCCEEEEEHHHCCCCCCEEEEEHHHHHH
RMREMSAMQPGMSFYGEMPDSFNFVLNTDHPLIKKVLTEEEQACDEKLKPILSDIKGWEA
HHHHHHHHCCCHHHHCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCH
RQADLREAQSKKKEDEITAQEKEDMTNTNHKLDELREQRNQVLAEYAGTNKTVSQLIDLA
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
LLGNGMLKGEALSQFIKRSVELIG
HHCCCCCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SSKQGNIGVTSENIFPIIKKFLYSDHEIFLRELVSNAVDATQKLKTLSSVGEFKGELGD
CCCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
LTVQVKFDDKTITISDRGIGMTAEEIDKYINQIAFSGAEEFVEKYKNDAASIIGHFGLGF
EEEEEEECCEEEEEECCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
YSSFMVSKKVEIVTKSYKEGAVPMKWSCDGTPEYSLEETTKEDRGTDIILYIDDENKDFL
HHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCCCCHHHHHHHCCCCEEEEEEECCCCCCC
NKDKINGLLTKYCRFLPVPIAFGKKQEWKDGKYVDTDEDNVINDTKPAWVRKPADMTDED
CHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHCCCCCCCCHHH
YKKFYRDLYPMTDEPLFWIHLNVDYPFNLTGILYFPRIKSNIDLHRNKIQLYCNQVFVTD
HHHHHHHHCCCCCCCEEEEEEEECCCCCCEEEEEECCCCCCCHHHHHHEEEEEEEEEEEC
SVEGIVPEFLTLLHGVLDSPDIPLNVSRSYLQSDQNVKKISNHITKKVADRLEEIFKNDR
CHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCC
PQFEEKWDSLKLFIQYGMLTDEKFYDRAVKFALFKDVEGKYFTFEEYKNLIKDNQTDKEG
CCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHCCCCCCCCC
NLIYLYTTNKDEQYSYIQAAKDKGYSVLEMDGQLDVHLIGQLEQKFEKSRFVRVDSDTID
CEEEEEECCCCCHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHCEEEECHHHHH
NLIRKEDSNKVTLSEEQKMAMQEVFKSQMPKLNKTEFYVTFEALGENANPVMLTQSEYMR
HHHHCCCCCCEEECHHHHHHHHHHHHHHCCCCCCCEEEEEHHHCCCCCCEEEEEHHHHHH
RMREMSAMQPGMSFYGEMPDSFNFVLNTDHPLIKKVLTEEEQACDEKLKPILSDIKGWEA
HHHHHHHHCCCHHHHCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCH
RQADLREAQSKKKEDEITAQEKEDMTNTNHKLDELREQRNQVLAEYAGTNKTVSQLIDLA
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
LLGNGMLKGEALSQFIKRSVELIG
HHCCCCCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11807048 [H]