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The map label for this gene is trpE [H]

Identifier: 150007246

GI number: 150007246

Start: 690775

End: 692178

Strand: Reverse

Name: trpE [H]

Synonym: BDI_0591

Alternate gene names: 150007246

Gene position: 692178-690775 (Counterclockwise)

Preceding gene: 150007247

Following gene: 150007245

Centisome position: 14.39

GC content: 53.99

Gene sequence:

>1404_bases
ATGAATTATTCTTTCAAAACGATAAGCAAGAAGGTGATGGGCGACCTTCACACTCCCGTAAGCATCTATCTGAAAGTGCG
GGATATCTACCCGGAATCGGCCCTGTTGGAAAGCTCGGACTTCCACGGAAACGAGAATAGCCTTTCCTTTATAGCGCTCC
GCCCCTTGGCGAGCATCGGTATCAACAACGGGGAATGCACGGCTACCTTCCCGGACGAGACCCGTGAGGTTACCCCGCTC
ACCGAAGACTATAACGTACCCGAGGCGATGAACGCTTTTCTCGGCCGCTTCAAGGTGGAGGGAGCGGACAAGAAGGTCTG
CGGATTATTCGGCTACACGGCTTTCGATGCCGTCCGTTATTTCGAGAACATCCCGGTCATGGAAGTTCATCACGAGGAGA
ACGACGCCCCCGATATGCTATACATATTATATAAGTATATCCTTGTCTTCAATCATTTCAAGAACGAGTTGACCCTAGTG
GAGATGCTCCAAGAGGACGAGGCTAGCCGGCTGGAAGAAATCGAGACATTGATCGAGAACCGTAACTTCGCCTCCTATAA
CTTCCAGACAGCGGGTCCCGAGACCTCCCCGATCACCGGCGAGGAATACAAGGCGATGGTCCGCCAAGGCATCAAGCACT
GCCTCAGGGGAGATGTCTTCCAGATCGTATTGAGCCGTCGCTTCGAGCAACCGTTCAAGGGAGACGACTTCAAGGTGTAC
CGGGCTCTTCGCAGCATCAATCCCTCTCCTTATTTGTTCTACTTCGATTTCGGAGGTTTCCGTATCTTCGGCTCTTCCCC
CGAGACGCATTGCAAGGTAACGGGCAGACACGCCAGCATCGACCCGATCGCCGGGACCGCTTTCCGTACCGGTAATATCG
AGGTAGACAAACAACGTACCGAGGCCCTGCTAGCCGACCCCAAGGAGAACGCCGAGCACGTGATGCTGGTAGACCTCGCC
CGCAACGACCTAAGCCGGAACGCCCACGACGTGCAAGTGGATTTCTATAAGGAGGTACAATACTACAGCCACGTCATCCA
CCTCGTATCCCGTGTGAGCGGCGAGATCAACGCCGATAGCGACCCGGTAAAGACCTACGTCGATACCTTCCCCGCCGGCA
CGTTGAGCGGAGCCCCCAAAGTACGGGCCATGCAACTGATCACCGACATCGAGCATCATAACCGGGGTGCTTACGGCGGC
TGTATCGGCTTTATCGGTCTGGATGGTGATTTGAACCAAGCGATCACGATCCGTACCTTCGTCAGCCGTGGCAACGTACT
TTACTATCAGGCGGGAGCCGGGATCGTGGCTAAGAGCAACGATGAGCGTGAATTGCAAGAGGTAAACAATAAGCTGGGAG
CCTTGAAGAAGGCGATAGATCTAGCGGAGAAATTAATCAATTGA

Upstream 100 bases:

>100_bases
CCTTGGCCAAGGTAAACTTCAAGCCGGAAGAGGTGGTGGTACTGACTGTCTCGGGCCGTGGCGATAAAGATATGGACACT
TACATTAATTATAAATTATC

Downstream 100 bases:

>100_bases
TTATCCGGTTGTAGAGACGGGGCACGCCCCGTCTCTACAACAACAATATATATAAAATGAAGATATTATTATTTGATAAT
TACGATTCCTTCACCTACAA

Product: anthranilate synthase component I

Products: NA

Alternate protein names: Anthranilate synthase component I [H]

Number of amino acids: Translated: 467; Mature: 467

Protein sequence:

>467_residues
MNYSFKTISKKVMGDLHTPVSIYLKVRDIYPESALLESSDFHGNENSLSFIALRPLASIGINNGECTATFPDETREVTPL
TEDYNVPEAMNAFLGRFKVEGADKKVCGLFGYTAFDAVRYFENIPVMEVHHEENDAPDMLYILYKYILVFNHFKNELTLV
EMLQEDEASRLEEIETLIENRNFASYNFQTAGPETSPITGEEYKAMVRQGIKHCLRGDVFQIVLSRRFEQPFKGDDFKVY
RALRSINPSPYLFYFDFGGFRIFGSSPETHCKVTGRHASIDPIAGTAFRTGNIEVDKQRTEALLADPKENAEHVMLVDLA
RNDLSRNAHDVQVDFYKEVQYYSHVIHLVSRVSGEINADSDPVKTYVDTFPAGTLSGAPKVRAMQLITDIEHHNRGAYGG
CIGFIGLDGDLNQAITIRTFVSRGNVLYYQAGAGIVAKSNDERELQEVNNKLGALKKAIDLAEKLIN

Sequences:

>Translated_467_residues
MNYSFKTISKKVMGDLHTPVSIYLKVRDIYPESALLESSDFHGNENSLSFIALRPLASIGINNGECTATFPDETREVTPL
TEDYNVPEAMNAFLGRFKVEGADKKVCGLFGYTAFDAVRYFENIPVMEVHHEENDAPDMLYILYKYILVFNHFKNELTLV
EMLQEDEASRLEEIETLIENRNFASYNFQTAGPETSPITGEEYKAMVRQGIKHCLRGDVFQIVLSRRFEQPFKGDDFKVY
RALRSINPSPYLFYFDFGGFRIFGSSPETHCKVTGRHASIDPIAGTAFRTGNIEVDKQRTEALLADPKENAEHVMLVDLA
RNDLSRNAHDVQVDFYKEVQYYSHVIHLVSRVSGEINADSDPVKTYVDTFPAGTLSGAPKVRAMQLITDIEHHNRGAYGG
CIGFIGLDGDLNQAITIRTFVSRGNVLYYQAGAGIVAKSNDERELQEVNNKLGALKKAIDLAEKLIN
>Mature_467_residues
MNYSFKTISKKVMGDLHTPVSIYLKVRDIYPESALLESSDFHGNENSLSFIALRPLASIGINNGECTATFPDETREVTPL
TEDYNVPEAMNAFLGRFKVEGADKKVCGLFGYTAFDAVRYFENIPVMEVHHEENDAPDMLYILYKYILVFNHFKNELTLV
EMLQEDEASRLEEIETLIENRNFASYNFQTAGPETSPITGEEYKAMVRQGIKHCLRGDVFQIVLSRRFEQPFKGDDFKVY
RALRSINPSPYLFYFDFGGFRIFGSSPETHCKVTGRHASIDPIAGTAFRTGNIEVDKQRTEALLADPKENAEHVMLVDLA
RNDLSRNAHDVQVDFYKEVQYYSHVIHLVSRVSGEINADSDPVKTYVDTFPAGTLSGAPKVRAMQLITDIEHHNRGAYGG
CIGFIGLDGDLNQAITIRTFVSRGNVLYYQAGAGIVAKSNDERELQEVNNKLGALKKAIDLAEKLIN

Specific function: Tryptophan biosynthesis; first step. [C]

COG id: COG0147

COG function: function code EH; Anthranilate/para-aminobenzoate synthases component I

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1787518, Length=376, Percent_Identity=37.7659574468085, Blast_Score=205, Evalue=6e-54,
Organism=Escherichia coli, GI1788114, Length=356, Percent_Identity=30.3370786516854, Blast_Score=170, Evalue=1e-43,
Organism=Escherichia coli, GI1786809, Length=256, Percent_Identity=26.5625, Blast_Score=90, Evalue=4e-19,
Organism=Escherichia coli, GI87082077, Length=303, Percent_Identity=26.7326732673267, Blast_Score=87, Evalue=2e-18,
Organism=Saccharomyces cerevisiae, GI6320935, Length=481, Percent_Identity=35.3430353430353, Blast_Score=232, Evalue=9e-62,
Organism=Saccharomyces cerevisiae, GI6324361, Length=385, Percent_Identity=25.974025974026, Blast_Score=99, Evalue=2e-21,

Paralogues:

None

Copy number: 700 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005801
- InterPro:   IPR019999
- InterPro:   IPR006805
- InterPro:   IPR005256
- InterPro:   IPR015890 [H]

Pfam domain/function: PF04715 Anth_synt_I_N; PF00425 Chorismate_bind [H]

EC number: =4.1.3.27 [H]

Molecular weight: Translated: 52565; Mature: 52565

Theoretical pI: Translated: 5.25; Mature: 5.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNYSFKTISKKVMGDLHTPVSIYLKVRDIYPESALLESSDFHGNENSLSFIALRPLASIG
CCCCHHHHHHHHHHCCCCCEEEEEEEEECCCCHHHCCCCCCCCCCCCEEEEEECCHHHCC
INNGECTATFPDETREVTPLTEDYNVPEAMNAFLGRFKVEGADKKVCGLFGYTAFDAVRY
CCCCEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHCEEECCCCCCHHHHHHHHHHHHHHH
FENIPVMEVHHEENDAPDMLYILYKYILVFNHFKNELTLVEMLQEDEASRLEEIETLIEN
HHCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHC
RNFASYNFQTAGPETSPITGEEYKAMVRQGIKHCLRGDVFQIVLSRRFEQPFKGDDFKVY
CCCCEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCHHHHH
RALRSINPSPYLFYFDFGGFRIFGSSPETHCKVTGRHASIDPIAGTAFRTGNIEVDKQRT
HHHHHCCCCCEEEEEECCCEEEECCCCCCCEEEECCCCCCCCCCCCEEECCCEEECHHHH
EALLADPKENAEHVMLVDLARNDLSRNAHDVQVDFYKEVQYYSHVIHLVSRVSGEINADS
HHHHCCCCCCCCEEEEEEEHHHHHCCCCCEEEEHHHHHHHHHHHHHHHHHHHCCCCCCCC
DPVKTYVDTFPAGTLSGAPKVRAMQLITDIEHHNRGAYGGCIGFIGLDGDLNQAITIRTF
CHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCEEEEEEE
VSRGNVLYYQAGAGIVAKSNDERELQEVNNKLGALKKAIDLAEKLIN
ECCCCEEEEECCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNYSFKTISKKVMGDLHTPVSIYLKVRDIYPESALLESSDFHGNENSLSFIALRPLASIG
CCCCHHHHHHHHHHCCCCCEEEEEEEEECCCCHHHCCCCCCCCCCCCEEEEEECCHHHCC
INNGECTATFPDETREVTPLTEDYNVPEAMNAFLGRFKVEGADKKVCGLFGYTAFDAVRY
CCCCEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHCEEECCCCCCHHHHHHHHHHHHHHH
FENIPVMEVHHEENDAPDMLYILYKYILVFNHFKNELTLVEMLQEDEASRLEEIETLIEN
HHCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHC
RNFASYNFQTAGPETSPITGEEYKAMVRQGIKHCLRGDVFQIVLSRRFEQPFKGDDFKVY
CCCCEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCHHHHH
RALRSINPSPYLFYFDFGGFRIFGSSPETHCKVTGRHASIDPIAGTAFRTGNIEVDKQRT
HHHHHCCCCCEEEEEECCCEEEECCCCCCCEEEECCCCCCCCCCCCEEECCCEEECHHHH
EALLADPKENAEHVMLVDLARNDLSRNAHDVQVDFYKEVQYYSHVIHLVSRVSGEINADS
HHHHCCCCCCCCEEEEEEEHHHHHCCCCCEEEEHHHHHHHHHHHHHHHHHHHCCCCCCCC
DPVKTYVDTFPAGTLSGAPKVRAMQLITDIEHHNRGAYGGCIGFIGLDGDLNQAITIRTF
CHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCEEEEEEE
VSRGNVLYYQAGAGIVAKSNDERELQEVNNKLGALKKAIDLAEKLIN
ECCCCEEEEECCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2844259 [H]