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The map label for this gene is trpB

Identifier: 150007247

GI number: 150007247

Start: 692175

End: 693359

Strand: Reverse

Name: trpB

Synonym: BDI_0592

Alternate gene names: 150007247

Gene position: 693359-692175 (Counterclockwise)

Preceding gene: 150007250

Following gene: 150007246

Centisome position: 14.41

GC content: 53.08

Gene sequence:

>1185_bases
ATGAAAACGTATCAAGTTGACAAGAATGGTTACTATGGTGAGTTCGGCGGGGCCTATGTTCCCGAGATCCTTCATCAATG
CGTGGAAAATTTACAGAATACCTATCTGCAAGTGTTGGAGAGCGATAGCTTCAAGGAAAAGTTCGATCAGTTATTGCGTG
ATTATGTAGGCCGCCCCTCCCCTCTTTACTTGGCCAAACGGTTGAGCGAGAAATACGGATGTAAGATCTATTTGAAACGG
GAAGACTTGAACCATACCGGAGCACATAAGATCAACAATACGATCGGCCAGATCCTCCTAGCCCGCCGCATGGGGAAGAG
CCGTATCATCGCCGAGACGGGTGCCGGACAGCATGGAGTGGCTACGGCTACGGTATGTGCCTTGATGAATATGGAATGTA
TCGTTTATATGGGGAAGACAGACGTGGAACGCCAACATGCCAACGTACAGAAGATGGAAATGCTGGGAGCTACCGTCGTG
CCCGTGACCTCGGGAAACATGACCTTGAAAGACGCCACGAACGAGGCGATCCGTGACTGGTGCTGTCATCCTTCGGATAC
GTATTATATTATCGGTTCTACGGTAGGCCCCCATCCTTATCCGGATATGGTAGCCCGGCTGCAATCCGTTATCAGCGAGG
AGATCAAGAAGCAACTGCTGGAGAAGGAAGGAAGGGATCACCCGGATTACCTGATCGCCTGCGTAGGCGGGGGAAGTAAC
GCCGCCGGTACGATCTATCATTTCGTGGACGACGAGCGGGTGAAGATCGTATTGGCCGAGGCCGGCGGCAAGGGCATCCA
CTCCGGCATGAGCGCCGCCACGATCCAATTGGGTAAAGAGGGCATCATCCACGGGGCACGTACCTTGGTCATGCAGAACG
AGGACGGACAGATCGAGGAACCTTATTCTGTTTCCGCCGGCTTGGATTACCCGGGCATCGGCCCGATCCACGCGAACCTC
TCCGTAAAGCACCGTGCGCAAATCCTAGCGGTTGATGATGACGAGGCGTTGGAGGCCGCTTTCGAGTTGACCCGTCTGGA
AGGAATCATCCCGGCCTTGGAAAGCGCCCATGCCTTGGGAGCCTTGGCCAAGGTAAACTTCAAGCCGGAAGAGGTGGTGG
TACTGACTGTCTCGGGCCGTGGCGATAAAGATATGGACACTTACATTAATTATAAATTATCATGA

Upstream 100 bases:

>100_bases
AAACACTACATAAAGATATAAAGAGGTCTGTCGCACTTGCGGCAGGCCTCTTTTCTTTTTATGGCAAATTCAAAAGGAAA
ATAACTAAAATAGATAAAAG

Downstream 100 bases:

>100_bases
ATTATTCTTTCAAAACGATAAGCAAGAAGGTGATGGGCGACCTTCACACTCCCGTAAGCATCTATCTGAAAGTGCGGGAT
ATCTACCCGGAATCGGCCCT

Product: tryptophan synthase subunit beta

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 394; Mature: 394

Protein sequence:

>394_residues
MKTYQVDKNGYYGEFGGAYVPEILHQCVENLQNTYLQVLESDSFKEKFDQLLRDYVGRPSPLYLAKRLSEKYGCKIYLKR
EDLNHTGAHKINNTIGQILLARRMGKSRIIAETGAGQHGVATATVCALMNMECIVYMGKTDVERQHANVQKMEMLGATVV
PVTSGNMTLKDATNEAIRDWCCHPSDTYYIIGSTVGPHPYPDMVARLQSVISEEIKKQLLEKEGRDHPDYLIACVGGGSN
AAGTIYHFVDDERVKIVLAEAGGKGIHSGMSAATIQLGKEGIIHGARTLVMQNEDGQIEEPYSVSAGLDYPGIGPIHANL
SVKHRAQILAVDDDEALEAAFELTRLEGIIPALESAHALGALAKVNFKPEEVVVLTVSGRGDKDMDTYINYKLS

Sequences:

>Translated_394_residues
MKTYQVDKNGYYGEFGGAYVPEILHQCVENLQNTYLQVLESDSFKEKFDQLLRDYVGRPSPLYLAKRLSEKYGCKIYLKR
EDLNHTGAHKINNTIGQILLARRMGKSRIIAETGAGQHGVATATVCALMNMECIVYMGKTDVERQHANVQKMEMLGATVV
PVTSGNMTLKDATNEAIRDWCCHPSDTYYIIGSTVGPHPYPDMVARLQSVISEEIKKQLLEKEGRDHPDYLIACVGGGSN
AAGTIYHFVDDERVKIVLAEAGGKGIHSGMSAATIQLGKEGIIHGARTLVMQNEDGQIEEPYSVSAGLDYPGIGPIHANL
SVKHRAQILAVDDDEALEAAFELTRLEGIIPALESAHALGALAKVNFKPEEVVVLTVSGRGDKDMDTYINYKLS
>Mature_394_residues
MKTYQVDKNGYYGEFGGAYVPEILHQCVENLQNTYLQVLESDSFKEKFDQLLRDYVGRPSPLYLAKRLSEKYGCKIYLKR
EDLNHTGAHKINNTIGQILLARRMGKSRIIAETGAGQHGVATATVCALMNMECIVYMGKTDVERQHANVQKMEMLGATVV
PVTSGNMTLKDATNEAIRDWCCHPSDTYYIIGSTVGPHPYPDMVARLQSVISEEIKKQLLEKEGRDHPDYLIACVGGGSN
AAGTIYHFVDDERVKIVLAEAGGKGIHSGMSAATIQLGKEGIIHGARTLVMQNEDGQIEEPYSVSAGLDYPGIGPIHANL
SVKHRAQILAVDDDEALEAAFELTRLEGIIPALESAHALGALAKVNFKPEEVVVLTVSGRGDKDMDTYINYKLS

Specific function: The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine

COG id: COG0133

COG function: function code E; Tryptophan synthase beta chain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the trpB family

Homologues:

Organism=Escherichia coli, GI1787515, Length=382, Percent_Identity=50.261780104712, Blast_Score=388, Evalue=1e-109,
Organism=Saccharomyces cerevisiae, GI6321412, Length=380, Percent_Identity=50.7894736842105, Blast_Score=389, Evalue=1e-109,

Paralogues:

None

Copy number: 360 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 5,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): TRPB_PARD8 (A6L9K4)

Other databases:

- EMBL:   CP000140
- RefSeq:   YP_001301990.1
- ProteinModelPortal:   A6L9K4
- SMR:   A6L9K4
- STRING:   A6L9K4
- GeneID:   5305747
- GenomeReviews:   CP000140_GR
- KEGG:   pdi:BDI_0592
- eggNOG:   COG0133
- HOGENOM:   HBG303148
- OMA:   LKREDLC
- ProtClustDB:   PRK04346
- BioCyc:   PDIS435591:BDI_0592-MONOMER
- HAMAP:   MF_00133
- InterPro:   IPR001926
- InterPro:   IPR006653
- InterPro:   IPR006654
- InterPro:   IPR023026
- TIGRFAMs:   TIGR00263

Pfam domain/function: PF00291 PALP; SSF53686 PyrdxlP-dep_enz_bsu

EC number: =4.2.1.20

Molecular weight: Translated: 43231; Mature: 43231

Theoretical pI: Translated: 6.02; Mature: 6.02

Prosite motif: PS00168 TRP_SYNTHASE_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTYQVDKNGYYGEFGGAYVPEILHQCVENLQNTYLQVLESDSFKEKFDQLLRDYVGRPS
CCCEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCC
PLYLAKRLSEKYGCKIYLKREDLNHTGAHKINNTIGQILLARRMGKSRIIAETGAGQHGV
HHHHHHHHHHHCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCH
ATATVCALMNMECIVYMGKTDVERQHANVQKMEMLGATVVPVTSGNMTLKDATNEAIRDW
HHHHHHHHHCCEEEEEECCCCCHHHHCCHHHHHHHCCEEEEEECCCEEEECCCHHHHHHH
CCHPSDTYYIIGSTVGPHPYPDMVARLQSVISEEIKKQLLEKEGRDHPDYLIACVGGGSN
CCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCC
AAGTIYHFVDDERVKIVLAEAGGKGIHSGMSAATIQLGKEGIIHGARTLVMQNEDGQIEE
CCCEEEEEECCCEEEEEEEECCCCCCCCCCCHHEEECCCCCHHCCEEEEEEECCCCCCCC
PYSVSAGLDYPGIGPIHANLSVKHRAQILAVDDDEALEAAFELTRLEGIIPALESAHALG
CCCCCCCCCCCCCCCEECCCEEEECEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALAKVNFKPEEVVVLTVSGRGDKDMDTYINYKLS
HHHCCCCCCCEEEEEEECCCCCCCCHHEEEEEEC
>Mature Secondary Structure
MKTYQVDKNGYYGEFGGAYVPEILHQCVENLQNTYLQVLESDSFKEKFDQLLRDYVGRPS
CCCEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCC
PLYLAKRLSEKYGCKIYLKREDLNHTGAHKINNTIGQILLARRMGKSRIIAETGAGQHGV
HHHHHHHHHHHCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCH
ATATVCALMNMECIVYMGKTDVERQHANVQKMEMLGATVVPVTSGNMTLKDATNEAIRDW
HHHHHHHHHCCEEEEEECCCCCHHHHCCHHHHHHHCCEEEEEECCCEEEECCCHHHHHHH
CCHPSDTYYIIGSTVGPHPYPDMVARLQSVISEEIKKQLLEKEGRDHPDYLIACVGGGSN
CCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCC
AAGTIYHFVDDERVKIVLAEAGGKGIHSGMSAATIQLGKEGIIHGARTLVMQNEDGQIEE
CCCEEEEEECCCEEEEEEEECCCCCCCCCCCHHEEECCCCCHHCCEEEEEEECCCCCCCC
PYSVSAGLDYPGIGPIHANLSVKHRAQILAVDDDEALEAAFELTRLEGIIPALESAHALG
CCCCCCCCCCCCCCCEECCCEEEECEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALAKVNFKPEEVVVLTVSGRGDKDMDTYINYKLS
HHHCCCCCCCEEEEEEECCCCCCCCHHEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA