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The map label for this gene is atpA

Identifier: 150006928

GI number: 150006928

Start: 292033

End: 293610

Strand: Reverse

Name: atpA

Synonym: BDI_0264

Alternate gene names: 150006928

Gene position: 293610-292033 (Counterclockwise)

Preceding gene: 150006929

Following gene: 150006927

Centisome position: 6.1

GC content: 53.74

Gene sequence:

>1578_bases
ATGACAGAACAGATAAAAGTGAGTGAAGTCTCCTCCATCCTGCGCCAGCAATTGGAAGGAATCCATACCAGCATCAAGCT
GGAAGAGGTCGGGACCGTATTGCAGGTGAGCGACGGCGTGGCCCGCATCTACGGGTTGGATAATGCGGAGGCGAACGAGT
TGCTTCAATTCGATAACGGGATGGAAGCAATCGTGATGAACTTGGAGGAAGATAATGTAGGCGCCGTCCTTTTAGGTCCG
ACCGACCAAATCAAGGAGGGCGACACCGTAAAACGCACGGGCCGTATCGCCTCTATCGATGTCAGCGAGGGGATGATCGG
GCGTGTGATCGATCCGTTGGGAAACCCGATCGACGGGAAAGGCGAGATCCTTGGCGAGACTTGCGAGATGCCGCTTGAGC
GCAAGGCTCCGGGCGTGATCTTCCGTCAGCCGGTAAACGAGCCTTTGCAAACCGGTATCAAGGCCGTAGACGCTATGATC
CCTATCGGGAGGGGGCAACGTGAGTTGATCATCGGCGACAGGCAGACGGGAAAGACCTCGATCGCTATCGATACCATCAT
CAACCAACGTAGCAACTACGAGGCAGGGAACCCGGTTTACTGTATTTACGTGGCGATCGGGCAAAAGGGTTCCACGGTAG
CGGCCTTGGTGAACACCTTGCAAGAGAAAGGAGCCATGGACTATACGATTGTCGTAAGCGCGACCGCCTCCGACCCGGCA
GCCATGCAATATTTCGCCCCGTTCGCCGGAGCGGCCATCGGAGAGTACTTCCGGGATAGCGGACGACACGCCTTGGTGGT
CTACGACGATCTGTCCAAACAGGCGGTCGCCTACCGTGAGGTTTCCTTGATCCTTCGCCGTCCTTCCGGACGTGAGGCGT
ACCCGGGTGATATCTTTTACCTGCACTCCCGCCTATTGGAACGTGCCGCCAAGATCATCAACCAGCCGGAGGTAGCCCGT
GAGATGAACGATCTCCCCGAAAGCATGAGAGACAAGGTGAAAGGCGGTGGCTCCTTGACCGCTTTACCGATCATCGAGAC
TCAGGCGGGAGACGTATCGGCTTATATCCCGACCAACGTGATCTCTATCACCGACGGACAGATATTCCTTGAGACCGATT
TATTCAACCAAGGGAACCGCCCAGCTATCAACGTCGGAATCTCTGTTTCCCGTGTAGGCGGTAACGCGCAATTAAAGGCG
ATGAAAAAGGTAGCGGGTACCTTGAAAATCGATCAGGCTCAGTTCCGTGAATTGGAATCATTTTCCAAGTTCGGGGGCGA
GATGGATGCCGTCACCGCTTTCACGATCGATAAAGGGCAGAAGAATACCCAGTTACTGATACAGCCTCAATATAGCCCGA
TGCCGGTGGAAGAGCAAATCTCGATCCTTTATTGCGGAACGCAAGGTCTGCTGAAAGAGGTTCCATTGGACAAGGTGCAT
GAGTTCGAGGCAAGGTTTTTGCAAGAGTTACGTACCTCTCACCAACGGGACGTACTGGATGTCTTAAAGACCGGCGTTAT
CAATGATGAGATACGAGGTATATTGGAAAAAACAGCGAAGGAGTTATGGGTTCATTGA

Upstream 100 bases:

>100_bases
CCGCCTACGCATCGGCAATTACCGGATAGACGCCAGCTATGCGACGCAACTACGGGATATCCGTACCGGGCTACTCGAAA
ACAGATAAAAAAGAAGAAGT

Downstream 100 bases:

>100_bases
AAGAAATAAAAGTCCGGATCGCCTCTATACGGAGCACGCAGAAGATCACCGCCGCCATGAAAATGGTATCGTCGGCCAAG
TTTCATCATGCCCAGACGCA

Product: F0F1 ATP synthase subunit alpha

Products: NA

Alternate protein names: ATP synthase F1 sector subunit alpha; F-ATPase subunit alpha

Number of amino acids: Translated: 525; Mature: 524

Protein sequence:

>525_residues
MTEQIKVSEVSSILRQQLEGIHTSIKLEEVGTVLQVSDGVARIYGLDNAEANELLQFDNGMEAIVMNLEEDNVGAVLLGP
TDQIKEGDTVKRTGRIASIDVSEGMIGRVIDPLGNPIDGKGEILGETCEMPLERKAPGVIFRQPVNEPLQTGIKAVDAMI
PIGRGQRELIIGDRQTGKTSIAIDTIINQRSNYEAGNPVYCIYVAIGQKGSTVAALVNTLQEKGAMDYTIVVSATASDPA
AMQYFAPFAGAAIGEYFRDSGRHALVVYDDLSKQAVAYREVSLILRRPSGREAYPGDIFYLHSRLLERAAKIINQPEVAR
EMNDLPESMRDKVKGGGSLTALPIIETQAGDVSAYIPTNVISITDGQIFLETDLFNQGNRPAINVGISVSRVGGNAQLKA
MKKVAGTLKIDQAQFRELESFSKFGGEMDAVTAFTIDKGQKNTQLLIQPQYSPMPVEEQISILYCGTQGLLKEVPLDKVH
EFEARFLQELRTSHQRDVLDVLKTGVINDEIRGILEKTAKELWVH

Sequences:

>Translated_525_residues
MTEQIKVSEVSSILRQQLEGIHTSIKLEEVGTVLQVSDGVARIYGLDNAEANELLQFDNGMEAIVMNLEEDNVGAVLLGP
TDQIKEGDTVKRTGRIASIDVSEGMIGRVIDPLGNPIDGKGEILGETCEMPLERKAPGVIFRQPVNEPLQTGIKAVDAMI
PIGRGQRELIIGDRQTGKTSIAIDTIINQRSNYEAGNPVYCIYVAIGQKGSTVAALVNTLQEKGAMDYTIVVSATASDPA
AMQYFAPFAGAAIGEYFRDSGRHALVVYDDLSKQAVAYREVSLILRRPSGREAYPGDIFYLHSRLLERAAKIINQPEVAR
EMNDLPESMRDKVKGGGSLTALPIIETQAGDVSAYIPTNVISITDGQIFLETDLFNQGNRPAINVGISVSRVGGNAQLKA
MKKVAGTLKIDQAQFRELESFSKFGGEMDAVTAFTIDKGQKNTQLLIQPQYSPMPVEEQISILYCGTQGLLKEVPLDKVH
EFEARFLQELRTSHQRDVLDVLKTGVINDEIRGILEKTAKELWVH
>Mature_524_residues
TEQIKVSEVSSILRQQLEGIHTSIKLEEVGTVLQVSDGVARIYGLDNAEANELLQFDNGMEAIVMNLEEDNVGAVLLGPT
DQIKEGDTVKRTGRIASIDVSEGMIGRVIDPLGNPIDGKGEILGETCEMPLERKAPGVIFRQPVNEPLQTGIKAVDAMIP
IGRGQRELIIGDRQTGKTSIAIDTIINQRSNYEAGNPVYCIYVAIGQKGSTVAALVNTLQEKGAMDYTIVVSATASDPAA
MQYFAPFAGAAIGEYFRDSGRHALVVYDDLSKQAVAYREVSLILRRPSGREAYPGDIFYLHSRLLERAAKIINQPEVARE
MNDLPESMRDKVKGGGSLTALPIIETQAGDVSAYIPTNVISITDGQIFLETDLFNQGNRPAINVGISVSRVGGNAQLKAM
KKVAGTLKIDQAQFRELESFSKFGGEMDAVTAFTIDKGQKNTQLLIQPQYSPMPVEEQISILYCGTQGLLKEVPLDKVHE
FEARFLQELRTSHQRDVLDVLKTGVINDEIRGILEKTAKELWVH

Specific function: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit

COG id: COG0056

COG function: function code C; F0F1-type ATP synthase, alpha subunit

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase alpha/beta chains family

Homologues:

Organism=Homo sapiens, GI50345984, Length=496, Percent_Identity=58.8709677419355, Blast_Score=584, Evalue=1e-167,
Organism=Homo sapiens, GI4757810, Length=496, Percent_Identity=58.8709677419355, Blast_Score=584, Evalue=1e-167,
Organism=Homo sapiens, GI19913428, Length=429, Percent_Identity=26.3403263403263, Blast_Score=105, Evalue=1e-22,
Organism=Homo sapiens, GI19913426, Length=428, Percent_Identity=25.9345794392523, Blast_Score=97, Evalue=3e-20,
Organism=Homo sapiens, GI32189394, Length=453, Percent_Identity=23.6203090507726, Blast_Score=85, Evalue=2e-16,
Organism=Homo sapiens, GI19913424, Length=274, Percent_Identity=27.7372262773723, Blast_Score=80, Evalue=4e-15,
Organism=Escherichia coli, GI1790172, Length=514, Percent_Identity=54.2801556420233, Blast_Score=534, Evalue=1e-153,
Organism=Escherichia coli, GI1790170, Length=436, Percent_Identity=24.3119266055046, Blast_Score=108, Evalue=9e-25,
Organism=Escherichia coli, GI1788251, Length=345, Percent_Identity=26.0869565217391, Blast_Score=91, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI71988063, Length=491, Percent_Identity=59.0631364562118, Blast_Score=588, Evalue=1e-168,
Organism=Caenorhabditis elegans, GI71988080, Length=491, Percent_Identity=59.0631364562118, Blast_Score=587, Evalue=1e-168,
Organism=Caenorhabditis elegans, GI71988074, Length=491, Percent_Identity=55.6008146639511, Blast_Score=537, Evalue=1e-153,
Organism=Caenorhabditis elegans, GI17570191, Length=423, Percent_Identity=26.241134751773, Blast_Score=100, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI17510931, Length=393, Percent_Identity=26.7175572519084, Blast_Score=100, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI71988068, Length=72, Percent_Identity=51.3888888888889, Blast_Score=83, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI25144756, Length=485, Percent_Identity=23.7113402061856, Blast_Score=81, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17509265, Length=50, Percent_Identity=66, Blast_Score=80, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17565854, Length=261, Percent_Identity=28.735632183908, Blast_Score=73, Evalue=4e-13,
Organism=Saccharomyces cerevisiae, GI6319370, Length=520, Percent_Identity=54.4230769230769, Blast_Score=572, Evalue=1e-164,
Organism=Saccharomyces cerevisiae, GI6319603, Length=336, Percent_Identity=27.9761904761905, Blast_Score=109, Evalue=1e-24,
Organism=Saccharomyces cerevisiae, GI6322581, Length=399, Percent_Identity=24.812030075188, Blast_Score=92, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24658560, Length=507, Percent_Identity=56.6074950690335, Blast_Score=582, Evalue=1e-166,
Organism=Drosophila melanogaster, GI281361666, Length=429, Percent_Identity=25.8741258741259, Blast_Score=103, Evalue=4e-22,
Organism=Drosophila melanogaster, GI24646341, Length=429, Percent_Identity=25.8741258741259, Blast_Score=103, Evalue=4e-22,
Organism=Drosophila melanogaster, GI17136796, Length=429, Percent_Identity=25.8741258741259, Blast_Score=103, Evalue=4e-22,
Organism=Drosophila melanogaster, GI24638766, Length=452, Percent_Identity=25, Blast_Score=85, Evalue=1e-16,
Organism=Drosophila melanogaster, GI28574560, Length=439, Percent_Identity=23.9179954441913, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24583988, Length=310, Percent_Identity=27.4193548387097, Blast_Score=78, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24583986, Length=310, Percent_Identity=27.4193548387097, Blast_Score=78, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24583984, Length=310, Percent_Identity=27.4193548387097, Blast_Score=78, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24583992, Length=310, Percent_Identity=27.4193548387097, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI20129479, Length=278, Percent_Identity=27.6978417266187, Blast_Score=75, Evalue=1e-13,

Paralogues:

None

Copy number: 9,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): ATPA_PARD8 (A6L8N5)

Other databases:

- EMBL:   CP000140
- RefSeq:   YP_001301671.1
- ProteinModelPortal:   A6L8N5
- SMR:   A6L8N5
- STRING:   A6L8N5
- GeneID:   5305419
- GenomeReviews:   CP000140_GR
- KEGG:   pdi:BDI_0264
- eggNOG:   COG0056
- HOGENOM:   HBG565875
- OMA:   EMALTLW
- ProtClustDB:   PRK09281
- BioCyc:   PDIS435591:BDI_0264-MONOMER
- HAMAP:   MF_01346
- InterPro:   IPR020003
- InterPro:   IPR000194
- InterPro:   IPR005294
- InterPro:   IPR017458
- InterPro:   IPR018118
- InterPro:   IPR000793
- InterPro:   IPR004100
- PANTHER:   PTHR15184:SF3
- TIGRFAMs:   TIGR00962

Pfam domain/function: PF00006 ATP-synt_ab; PF00306 ATP-synt_ab_C; PF02874 ATP-synt_ab_N; SSF47917 ATPase_a/b_C; SSF50615 ATPase_a/b_N

EC number: =3.6.3.14

Molecular weight: Translated: 57400; Mature: 57269

Theoretical pI: Translated: 4.76; Mature: 4.76

Prosite motif: PS00152 ATPASE_ALPHA_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEQIKVSEVSSILRQQLEGIHTSIKLEEVGTVLQVSDGVARIYGLDNAEANELLQFDNG
CCCCCCHHHHHHHHHHHHHHHHHEEEHHHHCCEEEECCCEEEEEECCCCCHHHHHHHCCC
MEAIVMNLEEDNVGAVLLGPTDQIKEGDTVKRTGRIASIDVSEGMIGRVIDPLGNPIDGK
CEEEEEEECCCCCCEEEECCCHHCCCCCCHHHCCCEEEEECCCCCHHHHHHHCCCCCCCC
GEILGETCEMPLERKAPGVIFRQPVNEPLQTGIKAVDAMIPIGRGQRELIIGDRQTGKTS
CCCCCHHHCCCCCCCCCCEEEECCCCHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCE
IAIDTIINQRSNYEAGNPVYCIYVAIGQKGSTVAALVNTLQEKGAMDYTIVVSATASDPA
EEHHHHHCCCCCCCCCCCEEEEEEEECCCCCHHHHHHHHHHHCCCCEEEEEEEECCCCCH
AMQYFAPFAGAAIGEYFRDSGRHALVVYDDLSKQAVAYREVSLILRRPSGREAYPGDIFY
HHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHEEHEEECCCCCCCCCCHHHH
LHSRLLERAAKIINQPEVAREMNDLPESMRDKVKGGGSLTALPIIETQAGDVSAYIPTNV
HHHHHHHHHHHHHCCCHHHHHHHHCHHHHHHHHCCCCCEEEEEEEEECCCCEEEECCCCE
ISITDGQIFLETDLFNQGNRPAINVGISVSRVGGNAQLKAMKKVAGTLKIDQAQFRELES
EEEECCEEEEEEECCCCCCCCEEEEEEEEEECCCCHHHHHHHHHHCCEEECHHHHHHHHH
FSKFGGEMDAVTAFTIDKGQKNTQLLIQPQYSPMPVEEQISILYCGTQGLLKEVPLDKVH
HHHCCCCCCEEEEEEECCCCCCCEEEEECCCCCCCHHHCEEEEEECCHHHHHHCCHHHHH
EFEARFLQELRTSHQRDVLDVLKTGVINDEIRGILEKTAKELWVH
HHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TEQIKVSEVSSILRQQLEGIHTSIKLEEVGTVLQVSDGVARIYGLDNAEANELLQFDNG
CCCCCHHHHHHHHHHHHHHHHHEEEHHHHCCEEEECCCEEEEEECCCCCHHHHHHHCCC
MEAIVMNLEEDNVGAVLLGPTDQIKEGDTVKRTGRIASIDVSEGMIGRVIDPLGNPIDGK
CEEEEEEECCCCCCEEEECCCHHCCCCCCHHHCCCEEEEECCCCCHHHHHHHCCCCCCCC
GEILGETCEMPLERKAPGVIFRQPVNEPLQTGIKAVDAMIPIGRGQRELIIGDRQTGKTS
CCCCCHHHCCCCCCCCCCEEEECCCCHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCE
IAIDTIINQRSNYEAGNPVYCIYVAIGQKGSTVAALVNTLQEKGAMDYTIVVSATASDPA
EEHHHHHCCCCCCCCCCCEEEEEEEECCCCCHHHHHHHHHHHCCCCEEEEEEEECCCCCH
AMQYFAPFAGAAIGEYFRDSGRHALVVYDDLSKQAVAYREVSLILRRPSGREAYPGDIFY
HHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHEEHEEECCCCCCCCCCHHHH
LHSRLLERAAKIINQPEVAREMNDLPESMRDKVKGGGSLTALPIIETQAGDVSAYIPTNV
HHHHHHHHHHHHHCCCHHHHHHHHCHHHHHHHHCCCCCEEEEEEEEECCCCEEEECCCCE
ISITDGQIFLETDLFNQGNRPAINVGISVSRVGGNAQLKAMKKVAGTLKIDQAQFRELES
EEEECCEEEEEEECCCCCCCCEEEEEEEEEECCCCHHHHHHHHHHCCEEECHHHHHHHHH
FSKFGGEMDAVTAFTIDKGQKNTQLLIQPQYSPMPVEEQISILYCGTQGLLKEVPLDKVH
HHHCCCCCCEEEEEEECCCCCCCEEEEECCCCCCCHHHCEEEEEECCHHHHHHCCHHHHH
EFEARFLQELRTSHQRDVLDVLKTGVINDEIRGILEKTAKELWVH
HHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA