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The map label for this gene is gpsA [H]

Identifier: 150006818

GI number: 150006818

Start: 159659

End: 160654

Strand: Reverse

Name: gpsA [H]

Synonym: BDI_0149

Alternate gene names: 150006818

Gene position: 160654-159659 (Counterclockwise)

Preceding gene: 150006819

Following gene: 150006817

Centisome position: 3.34

GC content: 46.29

Gene sequence:

>996_bases
ATGGATTTGCCCGGAAAAATCGCGATAATGGGAGGTGGTAGCTGGGCTACCGCCTTAGCCAAGATCGTACTTTCAACTCA
AGATAGTATCAACTGGTACATGCGTAGGCCCGATCGTATCGAGGAGTTCAAGCAGTTGGGACACAATCCGTGTTACCTCA
CCGCCGTGAAATTCGACACGAACAAGATAAACTTCTATTCCAATATCAACCAAGCGATCAAGGACTCGGATACCTTGATC
TTCGCTACGCCTTCCCCTTTCTTGAAACAACATTTGAAGAAGGTGAAGACCTCTTTGAAAGATAAGTTTATCATCTCGGC
GATCAAGGGTATCGTACCGGATGAGAATATGTTGATTACGGATTACTTCGCGGAGTATTACAAGGTTCCAACAGAAAATA
TAGCAGTTATCGGTGGTCCCTGTCATGCGGAAGAGATCGCTCTGGAACGGCTCTCGTACATTACGTTGGCTTGTTCTGAC
ATCGAGAAGGTCCGTACGATATCCCCCGTTTTCAAGAATCAATACTTAAAGAATTCCTTCTGTAAGGATGTGACCGGTAT
CGAATACGCCGCCGTACTGAAGAACGTGTACGCTATCGCCGCCGGTATTTGCCATGGAATGAAATATGGCGATAACTTCC
AAGCCGTATTTATCTCGAACGCTATTGAGGAGATGCGTAATTTCGTGGACGCCGTACACGGGCTGGAGCGGGATATCACC
GACTCCGTCTACCTTGGCGATTTGCTGGTTACCGCTTATTCCCGGTTCAGCCGTAACCGTACTTTCGGAACCATGATCGG
TAAAGGATATTCCGTGAAGACAGCGCAGCTGGAGATGGAAATGATCGCCGAGGGATATTATGGAACCAAGTGTATGCGTG
AGATCAACGAGAAATATAAAGTGAACATGCCGATACTGGACGCTGTTTATGATATATTGTACGAGAAGAAATCGCCGACA
ACGGTCATTCGTCAATTAACGGAAACGTTTAAATAA

Upstream 100 bases:

>100_bases
TTGCGAGCTTAATAAAAAATATAAGTTAGAACTGCAAAATCCTACGGTCCAAGAAATAGAAGCTTGGATAGCCAATGTAG
GAGAATAAAAGCGTGATACG

Downstream 100 bases:

>100_bases
AATAGCATATGAAAAACATCAGTTTAAACATCGACAAGGCTCTGGGCACTGTCTCCAAGGAACAGGTTTACGCTCAAGAG
GCCAAGGCAATGGAATGTAT

Product: glycerol-3-phosphate dehydrogenase

Products: NA

Alternate protein names: NAD(P)H-dependent glycerol-3-phosphate dehydrogenase [H]

Number of amino acids: Translated: 331; Mature: 331

Protein sequence:

>331_residues
MDLPGKIAIMGGGSWATALAKIVLSTQDSINWYMRRPDRIEEFKQLGHNPCYLTAVKFDTNKINFYSNINQAIKDSDTLI
FATPSPFLKQHLKKVKTSLKDKFIISAIKGIVPDENMLITDYFAEYYKVPTENIAVIGGPCHAEEIALERLSYITLACSD
IEKVRTISPVFKNQYLKNSFCKDVTGIEYAAVLKNVYAIAAGICHGMKYGDNFQAVFISNAIEEMRNFVDAVHGLERDIT
DSVYLGDLLVTAYSRFSRNRTFGTMIGKGYSVKTAQLEMEMIAEGYYGTKCMREINEKYKVNMPILDAVYDILYEKKSPT
TVIRQLTETFK

Sequences:

>Translated_331_residues
MDLPGKIAIMGGGSWATALAKIVLSTQDSINWYMRRPDRIEEFKQLGHNPCYLTAVKFDTNKINFYSNINQAIKDSDTLI
FATPSPFLKQHLKKVKTSLKDKFIISAIKGIVPDENMLITDYFAEYYKVPTENIAVIGGPCHAEEIALERLSYITLACSD
IEKVRTISPVFKNQYLKNSFCKDVTGIEYAAVLKNVYAIAAGICHGMKYGDNFQAVFISNAIEEMRNFVDAVHGLERDIT
DSVYLGDLLVTAYSRFSRNRTFGTMIGKGYSVKTAQLEMEMIAEGYYGTKCMREINEKYKVNMPILDAVYDILYEKKSPT
TVIRQLTETFK
>Mature_331_residues
MDLPGKIAIMGGGSWATALAKIVLSTQDSINWYMRRPDRIEEFKQLGHNPCYLTAVKFDTNKINFYSNINQAIKDSDTLI
FATPSPFLKQHLKKVKTSLKDKFIISAIKGIVPDENMLITDYFAEYYKVPTENIAVIGGPCHAEEIALERLSYITLACSD
IEKVRTISPVFKNQYLKNSFCKDVTGIEYAAVLKNVYAIAAGICHGMKYGDNFQAVFISNAIEEMRNFVDAVHGLERDIT
DSVYLGDLLVTAYSRFSRNRTFGTMIGKGYSVKTAQLEMEMIAEGYYGTKCMREINEKYKVNMPILDAVYDILYEKKSPT
TVIRQLTETFK

Specific function: De novo phospholipid biosynthesis; glycerol-3 phosphate formation. [C]

COG id: COG0240

COG function: function code C; Glycerol-3-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI33695088, Length=337, Percent_Identity=28.1899109792285, Blast_Score=105, Evalue=4e-23,
Organism=Homo sapiens, GI24307999, Length=339, Percent_Identity=25.9587020648968, Blast_Score=96, Evalue=4e-20,
Organism=Escherichia coli, GI1790037, Length=319, Percent_Identity=28.2131661442006, Blast_Score=139, Evalue=2e-34,
Organism=Caenorhabditis elegans, GI32564399, Length=349, Percent_Identity=24.6418338108883, Blast_Score=83, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI32564403, Length=358, Percent_Identity=24.5810055865922, Blast_Score=81, Evalue=8e-16,
Organism=Caenorhabditis elegans, GI193210136, Length=358, Percent_Identity=24.5810055865922, Blast_Score=81, Evalue=8e-16,
Organism=Saccharomyces cerevisiae, GI6324513, Length=346, Percent_Identity=23.4104046242775, Blast_Score=74, Evalue=4e-14,
Organism=Drosophila melanogaster, GI17136202, Length=341, Percent_Identity=26.3929618768328, Blast_Score=93, Evalue=2e-19,
Organism=Drosophila melanogaster, GI17136204, Length=341, Percent_Identity=26.3929618768328, Blast_Score=93, Evalue=3e-19,
Organism=Drosophila melanogaster, GI17136200, Length=341, Percent_Identity=26.3929618768328, Blast_Score=93, Evalue=3e-19,
Organism=Drosophila melanogaster, GI22026922, Length=274, Percent_Identity=27.007299270073, Blast_Score=78, Evalue=1e-14,
Organism=Drosophila melanogaster, GI45551945, Length=346, Percent_Identity=22.2543352601156, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI281362270, Length=284, Percent_Identity=22.887323943662, Blast_Score=73, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24648969, Length=308, Percent_Identity=22.0779220779221, Blast_Score=65, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008927
- InterPro:   IPR013328
- InterPro:   IPR006168
- InterPro:   IPR006109
- InterPro:   IPR011128
- InterPro:   IPR016040 [H]

Pfam domain/function: PF07479 NAD_Gly3P_dh_C; PF01210 NAD_Gly3P_dh_N [H]

EC number: =1.1.1.94 [H]

Molecular weight: Translated: 37456; Mature: 37456

Theoretical pI: Translated: 8.08; Mature: 8.08

Prosite motif: PS00957 NAD_G3PDH

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLPGKIAIMGGGSWATALAKIVLSTQDSINWYMRRPDRIEEFKQLGHNPCYLTAVKFDT
CCCCCEEEEEECCHHHHHHHHHHHHCCCHHHHHHCCCHHHHHHHHCCCCCEEEEEEEECC
NKINFYSNINQAIKDSDTLIFATPSPFLKQHLKKVKTSLKDKFIISAIKGIVPDENMLIT
CEEEHHHHHHHHHCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEHH
DYFAEYYKVPTENIAVIGGPCHAEEIALERLSYITLACSDIEKVRTISPVFKNQYLKNSF
HHHHHHHCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
CKDVTGIEYAAVLKNVYAIAAGICHGMKYGDNFQAVFISNAIEEMRNFVDAVHGLERDIT
HHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHCC
DSVYLGDLLVTAYSRFSRNRTFGTMIGKGYSVKTAQLEMEMIAEGYYGTKCMREINEKYK
CHHHHHHHHHHHHHHHHCCCCHHHHHCCCCEEEHHHHHHHHHHCCCCHHHHHHHHHHHHE
VNMPILDAVYDILYEKKSPTTVIRQLTETFK
ECCCHHHHHHHHHHCCCCHHHHHHHHHHHCC
>Mature Secondary Structure
MDLPGKIAIMGGGSWATALAKIVLSTQDSINWYMRRPDRIEEFKQLGHNPCYLTAVKFDT
CCCCCEEEEEECCHHHHHHHHHHHHCCCHHHHHHCCCHHHHHHHHCCCCCEEEEEEEECC
NKINFYSNINQAIKDSDTLIFATPSPFLKQHLKKVKTSLKDKFIISAIKGIVPDENMLIT
CEEEHHHHHHHHHCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEHH
DYFAEYYKVPTENIAVIGGPCHAEEIALERLSYITLACSDIEKVRTISPVFKNQYLKNSF
HHHHHHHCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
CKDVTGIEYAAVLKNVYAIAAGICHGMKYGDNFQAVFISNAIEEMRNFVDAVHGLERDIT
HHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHCC
DSVYLGDLLVTAYSRFSRNRTFGTMIGKGYSVKTAQLEMEMIAEGYYGTKCMREINEKYK
CHHHHHHHHHHHHHHHHCCCCHHHHHCCCCEEEHHHHHHHHHHCCCCHHHHHHHHHHHHE
VNMPILDAVYDILYEKKSPTTVIRQLTETFK
ECCCHHHHHHHHHHCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA